PL3368683T3 - Sposób ilościowego oznaczania pd-l1 - Google Patents

Sposób ilościowego oznaczania pd-l1

Info

Publication number
PL3368683T3
PL3368683T3 PL15795217T PL15795217T PL3368683T3 PL 3368683 T3 PL3368683 T3 PL 3368683T3 PL 15795217 T PL15795217 T PL 15795217T PL 15795217 T PL15795217 T PL 15795217T PL 3368683 T3 PL3368683 T3 PL 3368683T3
Authority
PL
Poland
Prior art keywords
quantification
Prior art date
Application number
PL15795217T
Other languages
English (en)
Inventor
Evrykleia LIANIDOU
Areti STRATI
Original Assignee
Pharmassist Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmassist Ltd filed Critical Pharmassist Ltd
Publication of PL3368683T3 publication Critical patent/PL3368683T3/pl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Liquid Crystal Substances (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
PL15795217T 2015-10-27 2015-10-27 Sposób ilościowego oznaczania pd-l1 PL3368683T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15795217.7A EP3368683B1 (en) 2015-10-27 2015-10-27 Method for the quantification of pd-l1
PCT/GR2015/000054 WO2017072539A1 (en) 2015-10-27 2015-10-27 Method for the quantification of pd-l1 expression

Publications (1)

Publication Number Publication Date
PL3368683T3 true PL3368683T3 (pl) 2020-07-27

Family

ID=54548209

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15795217T PL3368683T3 (pl) 2015-10-27 2015-10-27 Sposób ilościowego oznaczania pd-l1

Country Status (14)

Country Link
US (2) US20190085401A1 (pl)
EP (1) EP3368683B1 (pl)
CY (1) CY1122871T1 (pl)
DK (1) DK3368683T3 (pl)
ES (1) ES2779309T3 (pl)
HR (1) HRP20200487T1 (pl)
HU (1) HUE048265T2 (pl)
LT (1) LT3368683T (pl)
PL (1) PL3368683T3 (pl)
PT (1) PT3368683T (pl)
RS (1) RS60075B1 (pl)
SI (1) SI3368683T1 (pl)
SM (1) SMT202000159T1 (pl)
WO (1) WO2017072539A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11726089B2 (en) 2016-09-06 2023-08-15 Incelldx, Inc. Methods of assaying neoplastic and neoplasia-related cells and uses thereof
US12298309B2 (en) 2016-09-06 2025-05-13 Incelldx, Inc. Methods of assaying neoplastic and neoplasia-related cells and uses thereof
MX2019002578A (es) 2016-09-06 2019-09-18 Incelldx Inc Métodos de detección de la expresión del ligando 1 de muerte programada por célula y usos de los mismos.
CN107460239A (zh) * 2017-07-23 2017-12-12 嘉兴允英医学检验有限公司 一种用于pd‑l1表达水平检测的试剂盒
CN111433372B (zh) * 2017-10-19 2024-01-26 生物辐射实验室股份有限公司 具有光致发光的非常规和/或反向变化的数字扩增试验
CN108507992A (zh) * 2018-04-09 2018-09-07 苏州大学附属第医院 循环肿瘤细胞表面标志分子pd-l1的检测方法
EP3837354A4 (en) * 2018-08-16 2022-06-01 Musc Foundation for Research Development RECOMBINANT MYXOMA VIRUSES AND THEIR APPLICATIONS
WO2020092589A1 (en) * 2018-10-31 2020-05-07 Nantomics, Llc Immune checkpoint therapeutic methods
CN109576350B (zh) * 2019-01-18 2021-01-29 深圳恒特基因有限公司 一种dna与rna同时定量的试剂盒、方法及质控方法
CN109628596A (zh) * 2019-01-18 2019-04-16 臻悦生物科技江苏有限公司 Rna水平检测pd-1和pd-l1表达量的试剂盒及方法
WO2020214606A1 (en) * 2019-04-15 2020-10-22 The Medical College Of Wisconsin, Inc. Recombinant pd-l1 peptides and methods of use
CA3148731A1 (en) * 2019-09-24 2021-04-01 Qiagen Gmbh Multimodal analysis of stabilized cell-containing bodily fluid samples
EP4060346A4 (en) * 2020-02-18 2023-12-13 Innobation Bio Co., Ltd. COMPANION DIAGNOSTIC BIOMARKER COMPOSITION AND COMPANION DIAGNOSTIC KIT CONTAINING SAME
CN111521796A (zh) * 2020-04-21 2020-08-11 山东第一医科大学(山东省医学科学院) 一种检测肾癌患者外周血循环肿瘤细胞pd-l1表达的免疫荧光试剂盒及检测方法
WO2022040350A1 (en) * 2020-08-19 2022-02-24 Ohio State Innovation Foundation Highly sensitive platform to characterize extracellular vesicular biomarkers for cancer immunotherapy
CN112462072B (zh) * 2020-09-24 2022-06-03 浙江大学 一种tmub1蛋白在制备肿瘤免疫抑制分子检测剂中的应用
CN112725418A (zh) * 2021-01-25 2021-04-30 深圳乐土生物科技有限公司 基于游离rna检测pd-l1表达量的方法及其试剂盒
KR20230125672A (ko) * 2022-02-21 2023-08-29 사회복지법인 삼성생명공익재단 암 환자에 대한 면역관문억제제의 반응성 예측용 조성물
CN115961033A (zh) * 2022-10-19 2023-04-14 深圳海普洛斯医学检验实验室 一种cd274基因检测的探针引物组合、试剂盒及检测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6797813B2 (en) * 1996-09-23 2004-09-28 Schering Corporation AK155 antibodies and binding fragments thereof
AU2006304883A1 (en) 2005-10-21 2007-04-26 Genenews Inc. Method and apparatus for correlating levels of biomarker products with disease
GB201021149D0 (en) 2010-12-14 2011-01-26 Georg August Uni Gottingen Stiftung Offentlichen Rechts Use of a skin explant assay for mRNA expression analysis for the identification of new genes and drug targets associated with graft versus host disease
US20150071910A1 (en) 2013-03-15 2015-03-12 Genentech, Inc. Biomarkers and methods of treating pd-1 and pd-l1 related conditions
KR20250091304A (ko) * 2013-03-15 2025-06-20 제넨테크, 인크. Pd-1 및 pd-l1 관련 상태를 치료하기 위한 바이오마커 및 방법
TW201614237A (en) * 2014-09-05 2016-04-16 Medimmune Ltd Markers for identifying patients responsive to anti-PD-L1 antibody therapy

Also Published As

Publication number Publication date
ES2779309T3 (es) 2020-08-14
SMT202000159T1 (it) 2020-05-08
EP3368683B1 (en) 2020-01-15
EP3368683A1 (en) 2018-09-05
RS60075B1 (sr) 2020-05-29
HRP20200487T1 (hr) 2020-09-04
US12270081B2 (en) 2025-04-08
WO2017072539A1 (en) 2017-05-04
US20220073995A1 (en) 2022-03-10
PT3368683T (pt) 2020-04-06
SI3368683T1 (sl) 2020-07-31
CY1122871T1 (el) 2021-05-05
US20190085401A1 (en) 2019-03-21
LT3368683T (lt) 2020-04-10
HUE048265T2 (hu) 2020-08-28
DK3368683T3 (da) 2020-03-30

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