PL3387898T3 - Identyfikacja i monitorowanie immunoglobulin monoklonalnych na podstawie masy cząsteczkowej - Google Patents

Identyfikacja i monitorowanie immunoglobulin monoklonalnych na podstawie masy cząsteczkowej

Info

Publication number
PL3387898T3
PL3387898T3 PL18174068T PL18174068T PL3387898T3 PL 3387898 T3 PL3387898 T3 PL 3387898T3 PL 18174068 T PL18174068 T PL 18174068T PL 18174068 T PL18174068 T PL 18174068T PL 3387898 T3 PL3387898 T3 PL 3387898T3
Authority
PL
Poland
Prior art keywords
identification
monitoring
molecular weight
monoclonal immunoglobulins
immunoglobulins based
Prior art date
Application number
PL18174068T
Other languages
English (en)
Inventor
David R. Barnidge
David L. Murray
Original Assignee
Mayo Foundation For Medical Education And Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation For Medical Education And Research filed Critical Mayo Foundation For Medical Education And Research
Publication of PL3387898T3 publication Critical patent/PL3387898T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/6857—Antibody fragments
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL18174068T 2013-03-15 2014-03-10 Identyfikacja i monitorowanie immunoglobulin monoklonalnych na podstawie masy cząsteczkowej PL3387898T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361792944P 2013-03-15 2013-03-15
EP18174068.9A EP3387898B1 (en) 2013-03-15 2014-03-10 Identification and monitoring of monoclonal immunoglobulins by molecular mass
PCT/US2014/022475 WO2014150170A1 (en) 2013-03-15 2014-03-10 Identification and monitoring of monoclonal immunoglobulins by molecular mass
EP14770418.3A EP2966985B1 (en) 2013-03-15 2014-03-10 Identification and monitoring of monoclonal immunoglobulins by molecular mass

Publications (1)

Publication Number Publication Date
PL3387898T3 true PL3387898T3 (pl) 2020-10-19

Family

ID=51580707

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18174068T PL3387898T3 (pl) 2013-03-15 2014-03-10 Identyfikacja i monitorowanie immunoglobulin monoklonalnych na podstawie masy cząsteczkowej

Country Status (7)

Country Link
US (1) US12546782B2 (pl)
EP (3) EP3729958B1 (pl)
DK (2) DK3729958T3 (pl)
ES (3) ES2802805T3 (pl)
PL (1) PL3387898T3 (pl)
PT (1) PT3387898T (pl)
WO (1) WO2014150170A1 (pl)

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EP3353200A4 (en) * 2015-09-24 2019-06-26 Mayo Foundation for Medical Education and Research IDENTIFICATION OF FREE LIGHT CHAINS FROM IMMOBILIZED LOBULIN BY MASS SPECTROMETRY
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EP3682249A4 (en) 2017-09-13 2021-08-25 Mayo Foundation for Medical Education and Research IDENTIFICATION AND MONITORING OF ACID HYDROLYSIS PRODUCTS FROM IMMUNOGLOBULIN HEAVY CHAINS
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PT3387898T (pt) 2020-06-17
US12546782B2 (en) 2026-02-10
WO2014150170A1 (en) 2014-09-25
US20160041184A1 (en) 2016-02-11
ES2802805T3 (es) 2021-01-21
EP3387898B1 (en) 2020-05-13
DK3729958T3 (da) 2023-08-07
EP3729958B1 (en) 2023-05-03
EP2966985A1 (en) 2016-01-20
EP2966985B1 (en) 2018-09-19
ES2951899T3 (es) 2023-10-25
EP3729958A1 (en) 2020-10-28
EP3387898A1 (en) 2018-10-17
EP2966985A4 (en) 2017-03-15
DK3387898T3 (da) 2020-08-03
ES2702183T3 (es) 2019-02-27

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