PL3400025T3 - Stosowanie gwajakolu w zapobieganiu i leczeniu choroby spichrzeniowej glikogenu - Google Patents

Stosowanie gwajakolu w zapobieganiu i leczeniu choroby spichrzeniowej glikogenu

Info

Publication number
PL3400025T3
PL3400025T3 PL17736394.2T PL17736394T PL3400025T3 PL 3400025 T3 PL3400025 T3 PL 3400025T3 PL 17736394 T PL17736394 T PL 17736394T PL 3400025 T3 PL3400025 T3 PL 3400025T3
Authority
PL
Poland
Prior art keywords
guaiacol
prevention
treatment
storage disease
glycogen storage
Prior art date
Application number
PL17736394.2T
Other languages
English (en)
Inventor
Hasan Orhan AKMAN
Salvatore Dimauro
Or KAKHLON
Weil Miguel
Original Assignee
The Trustees Of Columbia University In The City Of New York
Hadasit Medical Research Services And Development Ltd.
Ramot At Tel-Aviv University Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Trustees Of Columbia University In The City Of New York, Hadasit Medical Research Services And Development Ltd., Ramot At Tel-Aviv University Ltd. filed Critical The Trustees Of Columbia University In The City Of New York
Publication of PL3400025T3 publication Critical patent/PL3400025T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/035Animal model for multifactorial diseases
    • A01K2267/0362Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/48Reserve carbohydrates, e.g. glycogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL17736394.2T 2016-01-06 2017-01-06 Stosowanie gwajakolu w zapobieganiu i leczeniu choroby spichrzeniowej glikogenu PL3400025T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662275471P 2016-01-06 2016-01-06
PCT/US2017/012455 WO2017120420A1 (en) 2016-01-06 2017-01-06 The use of guaiacol for the prevention and treatment of glycogen storage disease

Publications (1)

Publication Number Publication Date
PL3400025T3 true PL3400025T3 (pl) 2024-06-24

Family

ID=59274197

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17736394.2T PL3400025T3 (pl) 2016-01-06 2017-01-06 Stosowanie gwajakolu w zapobieganiu i leczeniu choroby spichrzeniowej glikogenu

Country Status (7)

Country Link
US (1) US10933031B2 (pl)
EP (1) EP3400025B1 (pl)
ES (1) ES2979171T3 (pl)
HU (1) HUE066497T2 (pl)
IL (1) IL260450B (pl)
PL (1) PL3400025T3 (pl)
WO (1) WO2017120420A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4497474A3 (en) * 2018-10-17 2025-04-23 Imbria Pharmaceuticals, Inc. Methods of treating rheumatic diseases using trimetazidine-based compounds
US11712432B2 (en) * 2018-12-20 2023-08-01 University Of Kentucky Research Foundation Method of treating cancer with an elevated glycogen content
US20230173037A1 (en) * 2020-03-09 2023-06-08 University Of Kentucky Research Foundation Manipulating Glycogen in Alzheimer’s Disease, Epilepsy, Traumatic Brain Injury, and ALS as a Treatment
CN120919090B (zh) * 2025-10-16 2025-12-23 山东第一医科大学附属省立医院(山东省立医院) 愈创木酚或其衍生物在制备预防或治疗代谢综合征药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06199695A (ja) 1992-03-06 1994-07-19 Yunie:Kk 糖尿病改善治療剤
GB0308952D0 (en) 2003-04-17 2003-05-28 St Georges Entpr Ltd Method
EP1684737A4 (en) 2003-11-07 2009-11-11 Oaky Natural Co Ltd PHARMACEUTICAL COMPOSITION WITH GUAIACOL DERIVATIVES AND SYRINGOL DERIVATIVES EXTRACTED FROM NATURAL VEGETABLE VINEGAR
CA2680063A1 (en) * 2007-02-23 2008-08-28 University Of Florida Research Foundation, Inc. Compositions and methods for treating glycogen storage diseases
EP2155197A4 (en) 2007-03-09 2011-10-12 Link Medicine Corp TREATMENT OF LYSOSOMAL STORAGE DISEASES
US8679478B2 (en) 2010-10-04 2014-03-25 Duke University Methods of lysosomal storage disease therapy
WO2016090001A1 (en) 2014-12-02 2016-06-09 The Trustees Of Columbia University In The City Of New York Deep intronic mutation found adult polyglucosan body disease and uses thereof
WO2016161086A1 (en) 2015-03-31 2016-10-06 Duke University Methods and compositions for treating glycogen storage diseases using agents that mimic or elevate cyclic amp

Also Published As

Publication number Publication date
ES2979171T3 (es) 2024-09-24
IL260450B (en) 2022-06-01
EP3400025B1 (en) 2024-03-13
US20190015355A1 (en) 2019-01-17
WO2017120420A1 (en) 2017-07-13
EP3400025A1 (en) 2018-11-14
US10933031B2 (en) 2021-03-02
EP3400025A4 (en) 2019-12-11
HUE066497T2 (hu) 2024-08-28
EP3400025C0 (en) 2024-03-13

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