PL340500A1 - Combination of active ingredients, in particular of tetrahydropyridines and acetylocholinesterases inhibiting agents, useful in treatment of senile dementia of alzheimer type - Google Patents

Combination of active ingredients, in particular of tetrahydropyridines and acetylocholinesterases inhibiting agents, useful in treatment of senile dementia of alzheimer type

Info

Publication number
PL340500A1
PL340500A1 PL98340500A PL34050098A PL340500A1 PL 340500 A1 PL340500 A1 PL 340500A1 PL 98340500 A PL98340500 A PL 98340500A PL 34050098 A PL34050098 A PL 34050098A PL 340500 A1 PL340500 A1 PL 340500A1
Authority
PL
Poland
Prior art keywords
acetylocholinesterases
tetrahydropyridines
useful
treatment
combination
Prior art date
Application number
PL98340500A
Other versions
PL194597B1 (en
Inventor
Jean-Pierre Maffrand
Philippe Soubrie
Jean-Paul Terranova
Original Assignee
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9714324A external-priority patent/FR2771006B1/en
Priority claimed from FR9714322A external-priority patent/FR2771007B1/en
Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo
Publication of PL340500A1 publication Critical patent/PL340500A1/en
Publication of PL194597B1 publication Critical patent/PL194597B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL98340500A 1997-11-14 1998-11-09 Combination of active ingredients, in particular of tetrahydropyridines and acetylocholinesterases inhibiting agents, useful in treatment of senile dementia of alzheimer type PL194597B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9714324A FR2771006B1 (en) 1997-11-14 1997-11-14 COMBINATION OF ACTIVE INGREDIENTS FOR THE TREATMENT OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
FR9714322A FR2771007B1 (en) 1997-11-14 1997-11-14 COMBINATION OF ACTIVE INGREDIENTS FOR THE TREATMENT OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
PCT/FR1998/002384 WO1999025363A1 (en) 1997-11-14 1998-11-09 Combination of active principles, in particular of tetrahydropyridins and acetylcholinesterase inhibiting agents, for treating senile dementia such as alzheimer dementia

Publications (2)

Publication Number Publication Date
PL340500A1 true PL340500A1 (en) 2001-02-12
PL194597B1 PL194597B1 (en) 2007-06-29

Family

ID=26233932

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98340500A PL194597B1 (en) 1997-11-14 1998-11-09 Combination of active ingredients, in particular of tetrahydropyridines and acetylocholinesterases inhibiting agents, useful in treatment of senile dementia of alzheimer type

Country Status (27)

Country Link
EP (1) EP1030671A1 (en)
JP (1) JP2001523642A (en)
KR (1) KR100599350B1 (en)
CN (1) CN1243540C (en)
AU (1) AU743228B2 (en)
BG (1) BG64819B1 (en)
BR (1) BR9814035A (en)
CA (1) CA2309966A1 (en)
CO (1) CO4980891A1 (en)
DZ (1) DZ2649A1 (en)
EA (1) EA003255B1 (en)
EE (1) EE04235B1 (en)
HU (1) HUP0100098A3 (en)
ID (1) ID24933A (en)
IL (2) IL136122A0 (en)
IS (1) IS5482A (en)
MY (1) MY120461A (en)
NO (1) NO20002450L (en)
NZ (1) NZ504420A (en)
OA (1) OA11464A (en)
PL (1) PL194597B1 (en)
SA (1) SA98190747B1 (en)
SK (1) SK286040B6 (en)
TR (1) TR200001262T2 (en)
TW (1) TW585766B (en)
UY (1) UY25247A1 (en)
WO (1) WO1999025363A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1514542T1 (en) 2002-06-14 2012-06-29 Toyama Chemical Co Ltd Medicinal composition comprising Tacrine or Donepezil for improving brain function.
ES2327914T3 (en) * 2002-08-07 2009-11-05 Novartis Ag METHOD FOR FORECASTING THE SENSITIVITY OF RAVASTIGMINE TREATMENT BASED ON THE APOE GENOTYPE OF PACINTES WITH DEMENTIA.
CN1520818A (en) * 2003-02-09 2004-08-18 ɽ����Ҷ��Ȼҩ���о��������޹�˾ Cholinesterase inhibitor pharmaceutical composition for treating senile dementia
JP2008525313A (en) 2004-12-27 2008-07-17 エーザイ・アール・アンド・ディー・マネジメント株式会社 Anti-dementia drug stabilization method
DK3099296T3 (en) 2014-01-31 2019-04-15 Cognition Therapeutics Inc ISO-INDOLINE DERIVATIVES, COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE
EP3634394B1 (en) * 2017-05-15 2025-12-24 Cognition Therapeutics, Inc. Compositions for treating neurodegenerative diseases
WO2019182319A1 (en) * 2018-03-20 2019-09-26 (주)인벤티지랩 Method for preparing pharmaceutical composition for preventing or treating cognitive disorder-associated diseases, and pharmaceutical composition for preventing or treating cognitive disorder-associated diseases, prepared by preparation method
KR102224917B1 (en) 2018-03-20 2021-03-09 (주)인벤티지랩 Production methods of preventing or treating cognitive impairment-related disease and preventing or treating cognitive impairment-related disease producing thereto
CN109265391B (en) * 2018-11-13 2021-11-19 枣庄学院 Biphenyl polysubstituted 1,2,5, 6-tetrahydropyridine compound and synthetic method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2662355B1 (en) * 1990-05-22 1994-11-10 Sanofi Sa USE OF 1- [2- (2-NAPHTYL) ETHYL] -4- (3-TRIFLUOROMETHYLPHENYL) -1,2,3,6-TETRAHYDROPYRIDINE FOR THE PREPARATION OF MEDICINES FOR THE TREATMENT OF BRAIN AND NEURAL DISORDERS.
US5453428A (en) * 1991-02-14 1995-09-26 The Mount Sinai School Of Medicine Of The City Of New York Method and composition for the treatment of apathy-amotivation syndrome
PT813416E (en) * 1995-03-06 2005-10-31 Interneuron Pharma REDUCING VOLUME OF FUNGUS USING CITICOLIN
FR2736053B1 (en) * 1995-06-28 1997-09-19 Sanofi Sa NEWS 1-PHENYLALKYL-1,2,3,6-TETRAHYDROPYRIDINES

Also Published As

Publication number Publication date
IL136122A0 (en) 2001-05-20
PL194597B1 (en) 2007-06-29
AU743228B2 (en) 2002-01-24
HUP0100098A2 (en) 2001-07-30
EE200000290A (en) 2001-06-15
WO1999025363A1 (en) 1999-05-27
IS5482A (en) 2000-05-09
OA11464A (en) 2003-11-18
HUP0100098A3 (en) 2001-12-28
CN1285742A (en) 2001-02-28
JP2001523642A (en) 2001-11-27
SK286040B6 (en) 2008-01-07
EE04235B1 (en) 2004-02-16
KR20010032099A (en) 2001-04-16
TR200001262T2 (en) 2001-01-22
AU1160999A (en) 1999-06-07
NZ504420A (en) 2003-08-29
SK7112000A3 (en) 2000-10-09
CN1243540C (en) 2006-03-01
KR100599350B1 (en) 2006-07-12
SA98190747B1 (en) 2006-11-04
UY25247A1 (en) 2001-05-31
IL136122A (en) 2006-07-05
MY120461A (en) 2005-10-31
CA2309966A1 (en) 1999-05-27
TW585766B (en) 2004-05-01
BR9814035A (en) 2000-09-26
EA003255B1 (en) 2003-02-27
NO20002450D0 (en) 2000-05-11
CO4980891A1 (en) 2000-11-27
BG64819B1 (en) 2006-05-31
DZ2649A1 (en) 2004-12-28
EA200000412A1 (en) 2000-12-25
BG104428A (en) 2001-08-31
EP1030671A1 (en) 2000-08-30
ID24933A (en) 2000-08-31
NO20002450L (en) 2000-07-14

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20081109