PL3415516T3 - Hapteny rysperydonu i paliperydonu - Google Patents

Hapteny rysperydonu i paliperydonu

Info

Publication number
PL3415516T3
PL3415516T3 PL18171270T PL18171270T PL3415516T3 PL 3415516 T3 PL3415516 T3 PL 3415516T3 PL 18171270 T PL18171270 T PL 18171270T PL 18171270 T PL18171270 T PL 18171270T PL 3415516 T3 PL3415516 T3 PL 3415516T3
Authority
PL
Poland
Prior art keywords
paliperidone
risperidone
haptens
Prior art date
Application number
PL18171270T
Other languages
English (en)
Inventor
Pieter Rik HASPESLAGH
Maarten VLIEGEN
Eric Hryhorenko
Thomas R. DECORY
Banumathi Sankaran
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PL3415516T3 publication Critical patent/PL3415516T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/77Ovalbumin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL18171270T 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu PL3415516T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261691469P 2012-08-21 2012-08-21
EP13753972.2A EP2888263B1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone
PCT/US2013/055729 WO2014031601A1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone
EP18171270.4A EP3415516B1 (en) 2012-08-21 2013-08-20 Haptens of risperidone and paliperidone

Publications (1)

Publication Number Publication Date
PL3415516T3 true PL3415516T3 (pl) 2022-03-28

Family

ID=49083786

Family Applications (2)

Application Number Title Priority Date Filing Date
PL13753972T PL2888263T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu
PL18171270T PL3415516T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL13753972T PL2888263T3 (pl) 2012-08-21 2013-08-20 Hapteny rysperydonu i paliperydonu

Country Status (11)

Country Link
US (1) US9012648B2 (pl)
EP (2) EP2888263B1 (pl)
JP (2) JP6131500B2 (pl)
CN (2) CN107082778A (pl)
AU (1) AU2013305936B2 (pl)
CA (1) CA2882560C (pl)
ES (2) ES2904838T3 (pl)
PL (2) PL2888263T3 (pl)
PT (2) PT3415516T (pl)
TR (1) TR201809424T4 (pl)
WO (1) WO2014031601A1 (pl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3321254T3 (pl) 2012-08-21 2021-01-11 Janssen Pharmaceutica Nv Hapteny arypiprazolu i ich zastosowanie w testach immunologicznych
CN110054694B (zh) 2012-08-21 2024-02-20 詹森药业有限公司 阿立哌唑半抗原的抗体及其用途
PL3333195T3 (pl) 2012-08-21 2021-02-22 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
PL3663317T3 (pl) 2012-08-21 2023-06-05 Janssen Pharmaceutica Nv Przeciwciała skierowane przeciwko haptenom kwetiapinowym i ich zastosowanie
JP6216926B2 (ja) 2012-08-21 2017-10-25 ヤンセン ファーマシューティカ エヌ.ベー. オランザピンに対する抗体及びその使用
AU2013305879B2 (en) 2012-08-21 2017-10-12 Saladax Biomedical Inc. Antibodies to aripiprazole and use thereof
US20140057303A1 (en) 2012-08-21 2014-02-27 Janssen Pharmaceutica Nv Antibodies to Olanzapine Haptens and Use Thereof
EP2888263B1 (en) * 2012-08-21 2018-05-09 Janssen Pharmaceutica NV Haptens of risperidone and paliperidone
HK1211958A1 (en) 2012-08-21 2016-06-03 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone and use thereof
PT3462173T (pt) * 2012-08-21 2021-04-28 Janssen Pharmaceutica Nv Anticorpos contra risperidona e utilização dos mesmos
WO2014031645A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc Antibodies to risperidone haptens and use thereof
CA2882489A1 (en) 2012-08-21 2014-02-27 Ortho-Clinical Diagnostics, Inc. Antibodies to paliperidone haptens and use thereof
AU2016372069A1 (en) * 2015-12-17 2018-06-07 Saladax Biomedical Inc. Antibodies to risperidone and use thereof
WO2017106508A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
CN107137715B (zh) * 2017-04-26 2019-02-19 石家庄蒎格医药科技有限公司 一种帕利哌酮聚乙二醇缀合前药及制备
CN110938072A (zh) * 2019-10-30 2020-03-31 杭州博拓生物科技股份有限公司 一种利培酮人工抗原及其制备方法
CN112608310B (zh) * 2020-12-17 2022-03-29 北京丹大生物技术有限公司 一种利培酮和9-羟基利培酮半抗原、抗原和抗体以及其应用
CN114685470B (zh) * 2020-12-25 2023-08-18 长沙博源医疗科技有限公司 一种利培酮关键基团衍生物、免疫原、抗利培酮特异性抗体及其制备方法与应用
CN116003404B (zh) * 2022-12-14 2024-10-01 杭州同舟生物技术有限公司 一种利培酮人工半抗原、人工抗原及其制备方法和应用

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US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
AU668159B2 (en) 1992-05-29 1996-04-26 Lilly Industries Limited Pharmaceutical compounds
US6034078A (en) 1992-05-29 2000-03-07 Eli Lilly And Company Limited Thienobenzodiazepine compounds
US5395933A (en) 1992-08-07 1995-03-07 Eastman Kodak Company Carbamazepine hapten analogues
US6958156B2 (en) 2000-12-15 2005-10-25 Vyrex Corporation Isoflavone derivatives
WO2003082877A1 (en) 2002-03-28 2003-10-09 Eli Lilly And Company Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
DK1546134T3 (da) 2002-08-05 2007-09-10 Lilly Co Eli Piperazinsubstituerede arylbenzodiazepiner
WO2005028458A1 (en) 2003-09-23 2005-03-31 Fermion Oy Preparation of quetiapine
TW200616604A (en) 2004-08-26 2006-06-01 Nicholas Piramal India Ltd Nitric oxide releasing prodrugs containing bio-cleavable linker
JP5249748B2 (ja) * 2005-04-25 2013-07-31 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 無菌3−[2−[4−(6−フルオロ−1,2−ベンズイソオキサゾール−3−イル)−1−ピペリジニル]エチル]−6,7,8,9−テトラヒドロ−9−ヒドロキシ−2−メチル−4H−ピリド[1,2−a]ピリミジン−4−オンパルミチン酸エステルの製造
CN101245065B (zh) * 2007-02-14 2010-05-19 江苏恩华药业股份有限公司 制备苯并异噁唑衍生物的方法及其中间体
CA2699062A1 (en) 2007-09-27 2009-04-02 Novartis Ag Drug monitoring assay
US20100069356A1 (en) 2008-09-17 2010-03-18 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
AU2009305203B2 (en) 2008-10-14 2013-03-07 Entasis Therapeutics Limited Fused, spirocyclic heteroaromatic compounds for the treatment of bacterial infections
EP2194048A1 (en) 2008-12-02 2010-06-09 Dirk Sartor Nitrate esters for the treatment of vascular and metabolic diseases
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US20110166156A1 (en) * 2010-01-07 2011-07-07 Alkermes, Inc. Prodrugs for the Treatment of Schizophrenia and Bipolar Disease
WO2011112657A1 (en) 2010-03-11 2011-09-15 Kempharm, Inc. Fatty acid conjugates of quetiapine, process for making and using the same
US8088594B2 (en) * 2010-03-16 2012-01-03 Saladax Biomedical Inc. Risperidone immunoassay
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
US8623324B2 (en) 2010-07-21 2014-01-07 Aat Bioquest Inc. Luminescent dyes with a water-soluble intramolecular bridge and their biological conjugates
WO2013088255A1 (en) 2011-12-15 2013-06-20 Alkermes Pharma Ireland Limited Prodrugs of secondary amine compounds
EP2888263B1 (en) * 2012-08-21 2018-05-09 Janssen Pharmaceutica NV Haptens of risperidone and paliperidone

Also Published As

Publication number Publication date
PT3415516T (pt) 2022-01-28
CN104755479A (zh) 2015-07-01
ES2669565T3 (es) 2018-05-28
TR201809424T4 (tr) 2018-07-23
CN107082778A (zh) 2017-08-22
EP2888263B1 (en) 2018-05-09
JP6131500B2 (ja) 2017-05-24
JP2017149731A (ja) 2017-08-31
JP2015526470A (ja) 2015-09-10
HK1211930A1 (en) 2016-06-03
AU2013305936A1 (en) 2015-03-05
US20140155585A1 (en) 2014-06-05
AU2013305936B2 (en) 2017-08-03
WO2014031601A1 (en) 2014-02-27
JP6667472B2 (ja) 2020-03-18
US9012648B2 (en) 2015-04-21
EP3415516A1 (en) 2018-12-19
PL2888263T3 (pl) 2018-10-31
CA2882560C (en) 2020-10-27
EP3415516B1 (en) 2021-12-15
CA2882560A1 (en) 2014-02-27
EP2888263A1 (en) 2015-07-01
CN104755479B (zh) 2016-11-09
ES2904838T3 (es) 2022-04-06
PT2888263T (pt) 2018-07-30

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