PL343435A1 - Glycine transport inhibitors - Google Patents

Glycine transport inhibitors

Info

Publication number: PL343435A1
Authority: PL; Poland
Prior art keywords: transport inhibitors; glycine transport; glycine; inhibitors; transport
Prior art date: 1998-03-06

Application number

PL99343435A

Inventor

Walter Herman Maria Lou Luyten

Frans Eduard Janssens

Ludo Edmond Josephine Kennis

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-06

Filing date

1999-02-26

Publication date

2001-08-13

1999-02-26 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2001-08-13 Publication of PL343435A1 publication Critical patent/PL343435A1/en

Links

DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 title 2
239000004471 Glycine Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

PL99343435A 1998-03-06 1999-02-26 Glycine transport inhibitors PL343435A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98200701		1998-03-06
PCT/EP1999/001309 WO1999044596A2 (en)	1998-03-06	1999-02-26	Glycine transport inhibitors

Publications (1)

Publication Number	Publication Date
PL343435A1 true PL343435A1 (en)	2001-08-13

Family

ID=8233444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL99343435A PL343435A1 (en)	1998-03-06	1999-02-26	Glycine transport inhibitors

Country Status (17)

Country	Link
EP (1)	EP1059922A2 (en)
JP (1)	JP2002505277A (en)
KR (1)	KR20010032968A (en)
CN (1)	CN1292698A (en)
AU (1)	AU3408999A (en)
BG (1)	BG104685A (en)
BR (1)	BR9907951A (en)
CA (1)	CA2322164A1 (en)
EE (1)	EE200000482A (en)
HR (1)	HRP20000523A2 (en)
HU (1)	HUP0101048A2 (en)
IL (1)	IL138228A0 (en)
NO (1)	NO20004431L (en)
PL (1)	PL343435A1 (en)
SK (1)	SK13082000A3 (en)
TR (1)	TR200002567T2 (en)
WO (1)	WO1999044596A2 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1400519B1 (en) *	1999-06-28	2007-03-07	Janssen Pharmaceutica N.V.	Respiratory syncytial virus replication inhibitors
UA73749C2 (en) *	1999-11-01	2005-09-15		Diarylenines
WO2001081308A2 (en) *	2000-04-20	2001-11-01	Nps Allelix Corp.	Aminopiperidines for use as glyt-1 inhibitors
DE10040016A1 (en) *	2000-08-16	2002-02-28	Boehringer Ingelheim Pharma	Novel beta-amyloid inhibitors, process for their preparation and their use as pharmaceuticals
CA2422198A1 (en)	2000-09-08	2002-03-14	Gliatech, Inc.	Substituted hydrazine derivatives
US6946474B2 (en)	2000-09-14	2005-09-20	Merck & Co., Inc.	Nitrogen-containing compounds and their use as glycine transport inhibitors
AR032653A1 (en)	2001-02-09	2003-11-19	Telik Inc	HYPERCYCLIC INHIBITORS OF THE GLICINE TRANSPORTER 2 PHARMACEUTICAL COMPOSITIONS, USE AND METHODS.
US7030150B2 (en)	2001-05-11	2006-04-18	Trimeris, Inc.	Benzimidazole compounds and antiviral uses thereof
ATE374610T1 (en) *	2003-09-09	2007-10-15	Hoffmann La Roche	1-(2-AMINO-BENZOYL)-PIPERAZINE DERIVATIVES AS GLYCINE ABSORPTION INHIBITORS FOR THE TREATMENT OF PSYCHOSIS
AU2004269892B2 (en)	2003-09-09	2010-03-11	F. Hoffmann-La Roche Ag	1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses
WO2005058885A2 (en) *	2003-12-18	2005-06-30	Glaxo Group Limited	Piperidine derivatives and their use as glycine transporter inhibitors
TW200630337A (en)	2004-10-14	2006-09-01	Euro Celtique Sa	Piperidinyl compounds and the use thereof
RU2395502C2 (en) *	2004-12-09	2010-07-27	Ф.Хоффманн-Ля Рош Аг	Phenyl-piperazine methanone derivatives
DE602005019465D1 (en)	2004-12-15	2010-04-01	Hoffmann La Roche	BI- AND TRICYCLIC SUBSTITUTED PHENYL-METHANONE AS INHIBITORS OF GLYCIN-I (GLYT-1) TRANSPORTERS FOR THE TREATMENT OF ALZHEIMER DISEASE
GB0428233D0 (en) *	2004-12-23	2005-01-26	Glaxo Group Ltd	Compounds
PE20061156A1 (en)	2004-12-23	2006-12-16	Glaxo Group Ltd	BENZAMIDE DERIVATIVES AS INHIBITING AGENTS OF THE GLYCINE TRANSPORTER
US7485637B2 (en)	2005-01-04	2009-02-03	Hoffmann-La Roche Inc.	Benzoyl-tetrahydropiperidine derivatives
CA2593453A1 (en) *	2005-01-06	2006-07-13	F. Hoffmann-La Roche Ag	Sulfanyl substituted phenyl methanones as glycine transporter 1 (glyt-1) inhibitors for the treatment of neurological and neuropsychiatric disorders
AU2005324024B2 (en) *	2005-01-07	2011-02-17	F. Hoffmann-La Roche Ag	[4-(Heteroaryl) piperazin-1-yl]-(2,5-substituted -phenyl)methanone derivatives as glycine transporter 1 (GlyT-1) inhibitors for the treatment of neurological and neuropsychiatric disorders
JP2008527016A (en)	2005-01-18	2008-07-24	エフ．ホフマン−ラロシュアーゲー	2,5-Disubstituted phenylmethanone derivatives as glycine transporter 1 (GlyT-1) inhibitors for the treatment of neurological and neuropsychiatric diseases
KR100915472B1 (en)	2005-01-26	2009-09-03	에프. 호프만-라 로슈 아게	Phenyl methanone derivatives and their use as glycine transporter 1 inhibitors
UA91536C2 (en) *	2005-02-07	2010-08-10	Ф. Хоффманн-Ля Рош Аг	Heterocyclic substituted phenyl methanones as inhibitors of the glycine transporter 1
CN100341871C (en) *	2005-06-03	2007-10-10	复旦大学	Organic sulfur compound containing piperidine structure, its preparation and use
US8247442B2 (en)	2006-03-29	2012-08-21	Purdue Pharma L.P.	Benzenesulfonamide compounds and their use
TW200812963A (en)	2006-04-13	2008-03-16	Euro Celtique Sa	Benzenesulfonamide compounds and the use thereof
TW200815353A (en)	2006-04-13	2008-04-01	Euro Celtique Sa	Benzenesulfonamide compounds and their use
PT2079485E (en) *	2006-11-01	2012-08-13	Purdue Pharma Lp	Phenylpropionamide compounds and the use thereof
FR2910320B1 (en) *	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	EMULSION COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
FR2910321B1 (en)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	CREAM GEL COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
US8399486B2 (en)	2007-04-09	2013-03-19	Purdue Pharma L.P.	Benzenesulfonyl compounds and the use thereof
US8765736B2 (en)	2007-09-28	2014-07-01	Purdue Pharma L.P.	Benzenesulfonamide compounds and the use thereof
WO2009075857A2 (en) *	2007-12-12	2009-06-18	Amgen Inc.	Glycine transporter-1 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1140119A (en) *	1978-04-03	1983-01-25	Joseph Torremans	N-heterocyclyl-4-piperidinamines
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
AU1041599A (en) *	1997-11-13	1999-06-07	Jose Luis Castro Pineiro	Therapeutic uses of triazolo-pyridazine derivatives

1999
- 1999-02-26 TR TR2000/02567T patent/TR200002567T2/en unknown
- 1999-02-26 WO PCT/EP1999/001309 patent/WO1999044596A2/en not_active Ceased
- 1999-02-26 AU AU34089/99A patent/AU3408999A/en not_active Abandoned
- 1999-02-26 HR HR20000523A patent/HRP20000523A2/en not_active Application Discontinuation
- 1999-02-26 EE EEP200000482A patent/EE200000482A/en unknown
- 1999-02-26 PL PL99343435A patent/PL343435A1/en not_active Application Discontinuation
- 1999-02-26 CN CN998036471A patent/CN1292698A/en active Pending
- 1999-02-26 KR KR1020007006315A patent/KR20010032968A/en not_active Withdrawn
- 1999-02-26 HU HU0101048A patent/HUP0101048A2/en unknown
- 1999-02-26 IL IL13822899A patent/IL138228A0/en unknown
- 1999-02-26 SK SK1308-2000A patent/SK13082000A3/en unknown
- 1999-02-26 BR BR9907951-8A patent/BR9907951A/en not_active Application Discontinuation
- 1999-02-26 JP JP2000534198A patent/JP2002505277A/en not_active Withdrawn
- 1999-02-26 EP EP99915541A patent/EP1059922A2/en not_active Withdrawn
- 1999-02-26 CA CA002322164A patent/CA2322164A1/en not_active Abandoned
2000
- 2000-08-11 BG BG104685A patent/BG104685A/en unknown
- 2000-09-05 NO NO20004431A patent/NO20004431L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU3408999A (en)	1999-09-20
WO1999044596A3 (en)	2000-02-17
BR9907951A (en)	2001-01-30
HUP0101048A2 (en)	2001-10-28
BG104685A (en)	2001-04-30
NO20004431D0 (en)	2000-09-05
TR200002567T2 (en)	2000-11-21
WO1999044596A2 (en)	1999-09-10
EE200000482A (en)	2002-02-15
SK13082000A3 (en)	2001-03-12
EP1059922A2 (en)	2000-12-20
NO20004431L (en)	2000-10-30
CN1292698A (en)	2001-04-25
IL138228A0 (en)	2001-10-31
HRP20000523A2 (en)	2001-02-28
KR20010032968A (en)	2001-04-25
JP2002505277A (en)	2002-02-19
CA2322164A1 (en)	1999-09-10

Legal Events

Date	Code	Title	Description
2007-07-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
IL138228A0 (en)	2001-10-31	Glycine transport inhibitors
IL138227A0 (en)	2001-10-31	Glycine transport inhibitors
GB2333747B (en)	2002-05-22	Transport system
ZA98376B (en)	1998-07-23	Sulfamide-metalloprotease inhibitors
GB2321641B (en)	2001-04-04	Sulfamide-metalloprotease inhibitors
PL331338A1 (en)	1999-07-05	Thiosulphonamidic metaloprotease inhibitors
PL342516A1 (en)	2001-06-18	Phospholipase a2 inhibitors
GB9917793D0 (en)	1999-09-29	Peptide transport
IL147697A0 (en)	2002-08-14	Phosphate transport inhibitors
ZA983762B (en)	1998-11-06	Protease inhibitors
EP1067894A4 (en)	2004-09-08	Protease inhibitors
IL152587A0 (en)	2003-05-29	Phosphate transport inhibitors
EP1079821A4 (en)	2001-08-29	Protease inhibitors
AU2030999A (en)	1999-07-26	Glycine transport inhibitors
AU7131698A (en)	1999-11-08	Polyamine transport inhibitors
GB9825854D0 (en)	1999-01-20	Peptide
GB9814952D0 (en)	1998-09-09	Transport device
AU1998899A (en)	2000-06-26	Polyamine transport inhibitors
AU2599099A (en)	1999-08-30	Tricyclic compounds as glycine transport inhibitors
GB9803553D0 (en)	1998-04-15	Transporting devices
HK1031833A (en)	2001-06-29	Glycine transport inhibitors
HK1031879A (en)	2001-06-29	Glycine transport inhibitors
GB9717117D0 (en)	1997-10-22	Transport device
GB2341818B (en)	2001-09-19	Disc transport system
GB9821864D0 (en)	1998-12-02	Transport