PL349217A1 - Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group - Google Patents
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groupInfo
- Publication number
- PL349217A1 PL349217A1 PL99349217A PL34921799A PL349217A1 PL 349217 A1 PL349217 A1 PL 349217A1 PL 99349217 A PL99349217 A PL 99349217A PL 34921799 A PL34921799 A PL 34921799A PL 349217 A1 PL349217 A1 PL 349217A1
- Authority
- PL
- Poland
- Prior art keywords
- herpes viruses
- heterocyclic carboxamide
- phenylenediamine group
- thiourea inhibitors
- inhibitors
- Prior art date
Links
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical group NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 title 1
- -1 Heterocyclic carboxamide Chemical class 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 241001529453 unidentified herpesvirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20855998A | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/028842 WO2000034258A2 (en) | 1998-12-09 | 1999-12-06 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL349217A1 true PL349217A1 (en) | 2002-07-01 |
Family
ID=22775044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL99349217A PL349217A1 (en) | 1998-12-09 | 1999-12-06 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1144397A3 (id) |
| JP (1) | JP2002531554A (id) |
| CN (1) | CN1348446A (id) |
| AU (1) | AU1934700A (id) |
| BG (1) | BG105581A (id) |
| BR (1) | BR9916046A (id) |
| CA (1) | CA2350767A1 (id) |
| CZ (1) | CZ20011956A3 (id) |
| EA (1) | EA200100631A1 (id) |
| HU (1) | HUP0200232A2 (id) |
| ID (1) | ID30158A (id) |
| IL (1) | IL143182A0 (id) |
| NO (1) | NO20012832L (id) |
| PL (1) | PL349217A1 (id) |
| SK (1) | SK7682001A3 (id) |
| TR (1) | TR200101664T2 (id) |
| WO (1) | WO2000034258A2 (id) |
| ZA (1) | ZA200104377B (id) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6166028A (en) * | 1998-12-09 | 2000-12-26 | American Home Products Corporation | Diaminopuridine-containing thiourea inhibitors of herpes viruses |
| US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
| WO2001064642A2 (en) | 2000-02-29 | 2001-09-07 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| US7220768B2 (en) * | 2003-02-11 | 2007-05-22 | Wyeth Holdings Corp. | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus |
| EP2077995B1 (en) | 2006-11-02 | 2012-02-08 | Millennium Pharmaceuticals, Inc. | Methods of synthesizing pharmaceutical salts of a factor xa inhibitor |
| EP2914592B1 (en) | 2012-11-03 | 2017-10-11 | Boehringer Ingelheim International GmbH | Inhibitors of cytomegalovirus |
| US9284310B2 (en) | 2012-11-03 | 2016-03-15 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| CN110565100B (zh) * | 2019-07-12 | 2021-05-07 | 西北工业大学 | 一种二茂钴阳离子基缓蚀剂及制备方法和使用方法 |
| WO2023011574A1 (zh) | 2021-08-05 | 2023-02-09 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和用途 |
| EP4433479A1 (en) | 2021-11-19 | 2024-09-25 | Basf Se | Bicyclic compounds for the control of invertebrate pests |
| CN115433093A (zh) * | 2022-09-26 | 2022-12-06 | 无锡双启科技有限公司 | 一种3-氯-4-三氟甲基苯胺的制备方法 |
| CN115710190A (zh) * | 2022-11-16 | 2023-02-24 | 常州佳德医药科技有限公司 | 4-甲氧基-2-氨基-n,n-二甲基苯胺、制备方法及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69811062T2 (de) * | 1997-04-10 | 2003-07-17 | Pharmacia & Upjohn Co., Kalamazoo | Polyaromatische antivirale zusammensetzungen |
-
1999
- 1999-12-06 ID IDW00200101231A patent/ID30158A/id unknown
- 1999-12-06 IL IL14318299A patent/IL143182A0/xx unknown
- 1999-12-06 AU AU19347/00A patent/AU1934700A/en not_active Abandoned
- 1999-12-06 CA CA002350767A patent/CA2350767A1/en not_active Abandoned
- 1999-12-06 CN CN99815997A patent/CN1348446A/zh active Pending
- 1999-12-06 EA EA200100631A patent/EA200100631A1/ru unknown
- 1999-12-06 HU HU0200232A patent/HUP0200232A2/hu unknown
- 1999-12-06 WO PCT/US1999/028842 patent/WO2000034258A2/en not_active Ceased
- 1999-12-06 EP EP99963023A patent/EP1144397A3/en not_active Withdrawn
- 1999-12-06 SK SK768-2001A patent/SK7682001A3/sk unknown
- 1999-12-06 PL PL99349217A patent/PL349217A1/xx not_active Application Discontinuation
- 1999-12-06 CZ CZ20011956A patent/CZ20011956A3/cs unknown
- 1999-12-06 BR BR9916046-3A patent/BR9916046A/pt not_active Application Discontinuation
- 1999-12-06 TR TR2001/01664T patent/TR200101664T2/xx unknown
- 1999-12-06 JP JP2000586705A patent/JP2002531554A/ja active Pending
-
2001
- 2001-05-28 ZA ZA200104377A patent/ZA200104377B/en unknown
- 2001-06-08 BG BG105581A patent/BG105581A/xx unknown
- 2001-06-08 NO NO20012832A patent/NO20012832L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0200232A2 (hu) | 2002-05-29 |
| EP1144397A3 (en) | 2002-09-11 |
| SK7682001A3 (en) | 2002-07-02 |
| CA2350767A1 (en) | 2000-06-15 |
| WO2000034258A2 (en) | 2000-06-15 |
| NO20012832D0 (no) | 2001-06-08 |
| ZA200104377B (en) | 2002-12-20 |
| IL143182A0 (en) | 2002-04-21 |
| JP2002531554A (ja) | 2002-09-24 |
| CN1348446A (zh) | 2002-05-08 |
| BR9916046A (pt) | 2001-10-02 |
| EP1144397A2 (en) | 2001-10-17 |
| ID30158A (id) | 2001-11-08 |
| WO2000034258A3 (en) | 2001-11-29 |
| CZ20011956A3 (cs) | 2001-10-17 |
| AU1934700A (en) | 2000-06-26 |
| TR200101664T2 (tr) | 2002-03-21 |
| BG105581A (en) | 2001-12-31 |
| NO20012832L (no) | 2001-08-07 |
| EA200100631A1 (ru) | 2002-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |