PL3501534T3 - Kompozycje szczepionkowe zawierające zmutowane białko wiążące czynnik h - Google Patents

Kompozycje szczepionkowe zawierające zmutowane białko wiążące czynnik h

Info

Publication number
PL3501534T3
PL3501534T3 PL18209661.0T PL18209661T PL3501534T3 PL 3501534 T3 PL3501534 T3 PL 3501534T3 PL 18209661 T PL18209661 T PL 18209661T PL 3501534 T3 PL3501534 T3 PL 3501534T3
Authority
PL
Poland
Prior art keywords
binding protein
vaccine compositions
mutated factor
mutated
factor
Prior art date
Application number
PL18209661.0T
Other languages
English (en)
Inventor
Rachel Exley
Christoph Tang
Susan M. Lea
Original Assignee
Ip2Ipo Innovations Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ip2Ipo Innovations Limited filed Critical Ip2Ipo Innovations Limited
Publication of PL3501534T3 publication Critical patent/PL3501534T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL18209661.0T 2008-10-25 2009-10-26 Kompozycje szczepionkowe zawierające zmutowane białko wiążące czynnik h PL3501534T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0819633.9A GB0819633D0 (en) 2008-10-25 2008-10-25 Composition

Publications (1)

Publication Number Publication Date
PL3501534T3 true PL3501534T3 (pl) 2024-04-02

Family

ID=40133849

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18209661.0T PL3501534T3 (pl) 2008-10-25 2009-10-26 Kompozycje szczepionkowe zawierające zmutowane białko wiążące czynnik h

Country Status (23)

Country Link
US (1) US20120052092A1 (pl)
EP (2) EP3501534B1 (pl)
JP (2) JP5676458B2 (pl)
KR (3) KR20110092282A (pl)
CN (2) CN105412920A (pl)
AU (1) AU2009306114B2 (pl)
BR (1) BRPI0919926A2 (pl)
CA (1) CA2741619A1 (pl)
CO (1) CO6382140A2 (pl)
DK (1) DK3501534T5 (pl)
ES (1) ES2970878T3 (pl)
FI (1) FI3501534T3 (pl)
GB (1) GB0819633D0 (pl)
HR (1) HRP20240226T1 (pl)
HU (1) HUE065348T2 (pl)
LT (1) LT3501534T (pl)
MX (1) MX2011004322A (pl)
NZ (2) NZ592444A (pl)
PL (1) PL3501534T3 (pl)
PT (1) PT3501534T (pl)
RU (1) RU2559528C2 (pl)
SI (1) SI3501534T1 (pl)
WO (1) WO2010046715A1 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2261345A3 (en) 1998-05-01 2012-01-11 Novartis Vaccines and Diagnostics, Inc. Neisseria meningitidis antigens and compositions
PT2270173E (pt) 1999-05-19 2016-03-28 Glaxosmithkline Biologicals Sa Composições de neisseria de combinação
PT2275552E (pt) 1999-10-29 2015-12-07 Glaxosmithkline Biolog Sa Péptidos antigénicos de neisseria
EP1261723B1 (en) 2000-02-28 2008-02-27 Novartis Vaccines and Diagnostics S.r.l. Hybrid expression of neisserial proteins
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
HUE047780T2 (hu) 2002-10-11 2020-05-28 Glaxosmithkline Biologicals Sa Polipeptid vakcinák hipervirulens meningokokkusz vonalak elleni széles-spektrumú védelemre
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
BRPI0907843A2 (pt) 2008-02-21 2015-08-04 Novartis Ag Polipeptídeos de fhbp menigocócicos
WO2009114485A2 (en) 2008-03-10 2009-09-17 Children's Hospital & Research Center At Oakland Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
CN104548082A (zh) 2009-03-24 2015-04-29 诺华股份有限公司 为脑膜炎球菌因子h结合蛋白添加佐剂
CA2759400A1 (en) 2009-04-30 2010-11-04 Children's Hospital & Research Center At Oakland Chimeric factor h binding proteins (fhbp) and methods of use
US20130022633A1 (en) * 2009-10-27 2013-01-24 University Of Florence MENINGOCOCCAL fHBP POLYPEPTIDES
CA2792683A1 (en) * 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Neisserial fhbp vaccine composition
EP2552942B1 (en) * 2010-03-30 2017-12-27 Children's Hospital & Research Center at Oakland Factor h binding proteins (fhbp) with altered properties and methods of use thereof
CA2803239A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
AU2013214105A1 (en) 2012-02-02 2014-07-24 Novartis Ag Promoters for increased protein expression in meningococcus
EP2861247B1 (en) 2012-06-14 2020-12-09 GlaxoSmithKline Biologicals SA Vaccines for serogroup x meningococcus
EP2877492A1 (en) 2012-07-27 2015-06-03 Institut National de la Santé et de la Recherche Médicale (INSERM) Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
WO2014140562A1 (en) * 2013-03-14 2014-09-18 Isis Innovation Limited Immunogenic composition to neisseria
BR112016002150A2 (pt) 2013-08-02 2017-09-12 Children´S Hospital & Res Center At Oakland proteínas de ligação de fator h de ocorrência natural (fhbp) e métodos de uso das mesmas
KR102779223B1 (ko) 2014-02-28 2025-03-07 글락소스미스클라인 바이오로지칼즈 에스.에이. 변형된 수막구균 fhbp 폴리펩티드
CA2955802C (en) 2014-07-23 2023-10-31 Children's Hospital & Research Center At Oakland Factor h binding protein variants and methods of use thereof
KR102709811B1 (ko) * 2014-08-20 2024-09-24 스티흐팅 산퀸 불드포르지닝 인자 h 강화 항체 및 그의 용도
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
CA3123887A1 (en) 2018-12-21 2020-06-25 Griffith University Compositions, methods and uses for eliciting an immune response
JP2022541757A (ja) * 2019-07-08 2022-09-27 クラポード バイオ，インコーポレイテッド リポオリゴ糖組成物およびワクチンの製造および使用方法
CN114828886B (zh) 2019-07-17 2025-04-18 双子治疗分公司 因子h增强抗体及其用途
KR20230147075A (ko) 2021-02-19 2023-10-20 사노피 파스퇴르 인크 수막구균 b 재조합 백신
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US5476784A (en) * 1993-04-06 1995-12-19 Rice; Peter A. Gonococcal anti-idiotypic antibodies and methods and compositions using them
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
CN1867354A (zh) * 2003-04-16 2006-11-22 惠氏控股有限公司 预防和治疗脑膜炎球菌疾病的新颖免疫原性组合物
ES2616294T3 (es) * 2005-01-27 2017-06-12 Children's Hospital & Research Center At Oakland Vacunas de vesículas basadas en GNA1870 para protección de amplio espectro contra enfermedades provocadas por Neisseria meningitidis
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
WO2008001224A2 (en) * 2006-06-29 2008-01-03 Novartis Ag Polypeptides from neisseria meningitidis
JP2013502918A (ja) * 2009-08-27 2013-01-31 ノバルティス アーゲー 髄膜炎菌ｆＨＢＰ配列を含むハイブリッドポリペプチド
EP2552942B1 (en) * 2010-03-30 2017-12-27 Children's Hospital & Research Center at Oakland Factor h binding proteins (fhbp) with altered properties and methods of use thereof

Also Published As

Publication number Publication date
FI3501534T3 (fi) 2024-02-09
EP3501534B1 (en) 2023-11-29
BRPI0919926A2 (pt) 2016-02-16
KR20110092282A (ko) 2011-08-17
MX2011004322A (es) 2011-06-16
CN102245202A (zh) 2011-11-16
JP2015063558A (ja) 2015-04-09
EP2355845B1 (en) 2018-12-05
HUE065348T2 (hu) 2024-05-28
HRP20240226T1 (hr) 2024-05-10
LT3501534T (lt) 2024-03-12
KR20190011836A (ko) 2019-02-07
EP2355845A1 (en) 2011-08-17
CO6382140A2 (es) 2012-02-15
SI3501534T1 (sl) 2024-03-29
EP3501534A1 (en) 2019-06-26
CA2741619A1 (en) 2010-04-29
ES2970878T3 (es) 2024-05-31
KR20170000390A (ko) 2017-01-02
JP6076326B2 (ja) 2017-02-08
DK3501534T5 (da) 2024-09-02
AU2009306114A1 (en) 2010-04-29
JP2012506411A (ja) 2012-03-15
JP5676458B2 (ja) 2015-02-25
NZ592444A (en) 2012-11-30
RU2559528C2 (ru) 2015-08-10
PT3501534T (pt) 2024-02-07
CN105412920A (zh) 2016-03-23
US20120052092A1 (en) 2012-03-01
WO2010046715A1 (en) 2010-04-29
RU2011120706A (ru) 2012-11-27
GB0819633D0 (en) 2008-12-03
DK3501534T3 (da) 2024-02-05
NZ601538A (en) 2014-01-31
AU2009306114B2 (en) 2015-10-01

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