BRPI0409459A - novas composições imunogênicas para a prevenção e tratamento de doença meningocócica - Google Patents
novas composições imunogênicas para a prevenção e tratamento de doença meningocócicaInfo
- Publication number
- BRPI0409459A BRPI0409459A BRPI0409459-0A BRPI0409459A BRPI0409459A BR PI0409459 A BRPI0409459 A BR PI0409459A BR PI0409459 A BRPI0409459 A BR PI0409459A BR PI0409459 A BRPI0409459 A BR PI0409459A
- Authority
- BR
- Brazil
- Prior art keywords
- immunogenic compositions
- prevention
- treatment
- immunogenic
- meningococcal disease
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 208000037941 meningococcal disease Diseases 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000034762 Meningococcal Infections Diseases 0.000 abstract 1
- 241000588653 Neisseria Species 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Cell Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"NOVAS COMPOSIçõES IMUNOGêNICAS PARA A PREVENçãO E TRATAMENTO DE DOENçA MENINGOCóCICA". A presente invenção se refere a proteínas de Neisseria ORF2086, proteínas imunogênicas de reação cruzada que podem ser isoladas de cepas nesserial ou preparadas recombinantemente, incluindo porções imunogênicas destas, equivalentes biológicos destas, anticorpos que se ligam imunoespecificamente às precedentes e seqüências de ácido nucléico que codificam cada uma das precedentes, bem como ao uso das mesmas em composições imunogênicas que são efetivas contra infecção por Neisseria meningitidis de grupo de soro B.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46316103P | 2003-04-16 | 2003-04-16 | |
| PCT/US2004/011901 WO2004094596A2 (en) | 2003-04-16 | 2004-04-16 | Novel immunogenic compositions for the prevention and treatment of meningococcal disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0409459A true BRPI0409459A (pt) | 2006-05-02 |
Family
ID=33310752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0409459-0A BRPI0409459A (pt) | 2003-04-16 | 2004-04-16 | novas composições imunogênicas para a prevenção e tratamento de doença meningocócica |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20070253964A1 (pt) |
| EP (1) | EP1618185A4 (pt) |
| JP (1) | JP2006525330A (pt) |
| KR (1) | KR20060019515A (pt) |
| CN (1) | CN1867354A (pt) |
| AU (2) | AU2004233012A1 (pt) |
| BR (1) | BRPI0409459A (pt) |
| CA (1) | CA2522751A1 (pt) |
| CO (1) | CO5700785A2 (pt) |
| MX (1) | MXPA05011110A (pt) |
| WO (1) | WO2004094596A2 (pt) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2261338A3 (en) | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| NZ515935A (en) | 1999-05-19 | 2004-01-30 | Chiron S | Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis |
| JP2004508801A (ja) | 1999-10-29 | 2004-03-25 | カイロン ソチエタ ア レスポンサビリタ リミタータ | ナイセリア抗原性ペプチド |
| NZ521531A (en) | 2000-02-28 | 2005-12-23 | Chiron S | Heterologous expression of neisserial proteins |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
| EP3311836A1 (en) | 2005-04-08 | 2018-04-25 | Wyeth LLC | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| EP1943269A2 (en) * | 2005-10-14 | 2008-07-16 | Intercell AG | Neisseria meningitidis antigens |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| TW200806315A (en) | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
| SG174013A1 (en) | 2006-07-27 | 2011-09-29 | Wyeth Corp | High-cell density fed-batch fermentation process for producing recombinant protein |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| CN102356089B (zh) | 2008-02-21 | 2014-02-19 | 诺华股份有限公司 | 脑膜炎球菌fHBP多肽 |
| GB0819633D0 (en) * | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
| EP2411048B1 (en) | 2009-03-24 | 2020-05-06 | GlaxoSmithKline Biologicals SA | Adjuvanting meningococcal factor h binding protein |
| CN102596240B (zh) | 2009-08-27 | 2015-02-04 | 诺华股份有限公司 | 包括脑膜炎球菌fHBP序列的杂交多肽 |
| CA2779816A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
| CA2792687A1 (en) * | 2010-03-10 | 2011-09-15 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
| AU2011252844B2 (en) * | 2010-05-14 | 2014-07-03 | Baxalta GmbH | Chimeric OspA genes, proteins, and methods of use thereof |
| PL2575870T3 (pl) | 2010-06-04 | 2017-05-31 | Wyeth Llc | Preparaty szczepionek |
| AU2011268507B2 (en) | 2010-06-25 | 2014-08-14 | Novartis Ag | Combinations of meningococcal factor H binding proteins |
| CN107913396B (zh) | 2010-08-23 | 2022-03-08 | 惠氏有限责任公司 | 脑膜炎萘瑟氏菌rLP2086抗原的稳定制剂 |
| AU2011300409B2 (en) * | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
| JP2015505309A (ja) | 2011-12-29 | 2015-02-19 | ノバルティス アーゲー | 髄膜炎菌h因子結合タンパク質のアジュバントされた組み合わせ |
| MY198910A (en) * | 2012-03-09 | 2023-10-02 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| AU2013276083B2 (en) | 2012-06-14 | 2018-04-05 | Institut Pasteur | Vaccines for serogroup X meningococcus |
| WO2014016152A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| WO2014136064A2 (en) * | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| KR20160127104A (ko) | 2014-02-28 | 2016-11-02 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 변형된 수막구균 fhbp 폴리펩티드 |
| WO2016132294A1 (en) * | 2015-02-19 | 2016-08-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| AU2018215585B2 (en) | 2017-01-31 | 2022-03-17 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| WO2021059181A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| GB202016604D0 (en) * | 2020-10-20 | 2020-12-02 | Univ Of Oxford | Compositions and methods for inducing an immune response |
| CN113372571A (zh) * | 2021-07-05 | 2021-09-10 | 云南紫辰集团生物科技有限公司 | 黄腐酸钾干粉的生产工艺 |
| CN114295845B (zh) * | 2021-12-01 | 2024-07-19 | 柏荣诊断产品(上海)有限公司 | 一种高特异性透散射一体法降钙素原胶乳比浊检测试剂盒 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US466829A (en) * | 1892-01-12 | Carpet-stretcher | ||
| US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4554101A (en) * | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| US4650764A (en) * | 1983-04-12 | 1987-03-17 | Wisconsin Alumni Research Foundation | Helper cell |
| US4797368A (en) * | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
| US4666829A (en) * | 1985-05-15 | 1987-05-19 | University Of California | Polypeptide marker for Alzheimer's disease and its use for diagnosis |
| US5139941A (en) * | 1985-10-31 | 1992-08-18 | University Of Florida Research Foundation, Inc. | AAV transduction vectors |
| US4861719A (en) * | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
| US4980289A (en) * | 1987-04-27 | 1990-12-25 | Wisconsin Alumni Research Foundation | Promoter deficient retroviral vector |
| US5124263A (en) * | 1989-01-12 | 1992-06-23 | Wisconsin Alumni Research Foundation | Recombination resistant retroviral helper cell and products produced thereby |
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) * | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5264618A (en) * | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| JPH07502646A (ja) * | 1991-10-21 | 1995-03-23 | メディミューン,インコーポレーテッド | リポタンパク質の分泌シグナルをコード化するdnaを含む細菌発現ベクター |
| FR2708622B1 (fr) * | 1993-08-02 | 1997-04-18 | Raymond Hamers | Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides. |
| US5739118A (en) * | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| DE19723095C2 (de) * | 1997-06-02 | 2001-08-23 | Siemens Ag | Bildrekonstruktionsverfahren für einen Computertomographen |
| EP1053329B1 (en) * | 1998-02-03 | 2009-10-07 | Centers for Disease Control & Prevention | RECOMBINANT LIPIDATED PsaA PROTEIN, METHODS OF PREPARATION AND USE |
| EP2261338A3 (en) * | 1998-05-01 | 2012-01-04 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| PT1117435E (pt) * | 1998-09-30 | 2008-02-21 | Us Gov Univ Health Sciences | Holotoxina da cólera mutante como adjuvante |
| US20070020622A1 (en) * | 2001-09-14 | 2007-01-25 | Invitrogen Corporation | DNA Polymerases and mutants thereof |
| MX339524B (es) * | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0227346D0 (en) * | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
-
2004
- 2004-04-16 BR BRPI0409459-0A patent/BRPI0409459A/pt not_active IP Right Cessation
- 2004-04-16 CN CNA2004800163535A patent/CN1867354A/zh active Pending
- 2004-04-16 MX MXPA05011110A patent/MXPA05011110A/es not_active Application Discontinuation
- 2004-04-16 KR KR1020057019725A patent/KR20060019515A/ko not_active Ceased
- 2004-04-16 CA CA002522751A patent/CA2522751A1/en not_active Abandoned
- 2004-04-16 WO PCT/US2004/011901 patent/WO2004094596A2/en not_active Ceased
- 2004-04-16 AU AU2004233012A patent/AU2004233012A1/en not_active Abandoned
- 2004-04-16 US US10/553,670 patent/US20070253964A1/en not_active Abandoned
- 2004-04-16 EP EP04759967A patent/EP1618185A4/en not_active Withdrawn
- 2004-04-16 JP JP2006513095A patent/JP2006525330A/ja active Pending
-
2005
- 2005-11-16 CO CO05116231A patent/CO5700785A2/es not_active Application Discontinuation
-
2006
- 2006-12-14 US US11/638,520 patent/US20070082007A1/en not_active Abandoned
- 2006-12-14 US US11/638,443 patent/US20070082006A1/en not_active Abandoned
- 2006-12-14 US US11/638,401 patent/US20070082866A1/en not_active Abandoned
-
2008
- 2008-06-16 US US12/214,043 patent/US20090202593A1/en not_active Abandoned
-
2010
- 2010-03-10 AU AU2010200892A patent/AU2010200892A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20070253964A1 (en) | 2007-11-01 |
| US20070082006A1 (en) | 2007-04-12 |
| EP1618185A4 (en) | 2009-05-27 |
| KR20060019515A (ko) | 2006-03-03 |
| CA2522751A1 (en) | 2004-11-04 |
| CO5700785A2 (es) | 2006-11-30 |
| AU2004233012A1 (en) | 2004-11-04 |
| CN1867354A (zh) | 2006-11-22 |
| EP1618185A2 (en) | 2006-01-25 |
| AU2010200892A1 (en) | 2010-04-01 |
| JP2006525330A (ja) | 2006-11-09 |
| WO2004094596A2 (en) | 2004-11-04 |
| US20090202593A1 (en) | 2009-08-13 |
| US20070082866A1 (en) | 2007-04-12 |
| US20070082007A1 (en) | 2007-04-12 |
| MXPA05011110A (es) | 2006-01-24 |
| WO2004094596A8 (en) | 2006-06-15 |
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