PL354991A1 - Sodium 2-(4,6-dimethyl-pyrimidin-2-yloxy)-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate and use thereof as endothelin antagonist - Google Patents

Sodium 2-(4,6-dimethyl-pyrimidin-2-yloxy)-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate and use thereof as endothelin antagonist

Info

Publication number: PL354991A1
Authority: PL; Poland
Prior art keywords: diphenylpropionate; dimethoxyphenyl; yloxy; pyrimidin; ethoxy
Prior art date: 1999-10-26

Application number

PL00354991A

Other languages

Polish (pl)

Inventor

Rolf Jansen

Original Assignee

Basf Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-26

Filing date

2000-10-17

Publication date

2004-03-22

2000-10-17 Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft

2004-03-22 Publication of PL354991A1 publication Critical patent/PL354991A1/en

Links

239000002308 endothelin receptor antagonist Substances 0.000 title 1
HTRPIHRNVLLBGC-UHFFFAOYSA-M sodium;3-[2-(3,4-dimethoxyphenyl)ethoxy]-2-(4,6-dimethylpyrimidin-2-yl)oxy-3,3-diphenylpropanoate Chemical compound [Na+].C1=C(OC)C(OC)=CC=C1CCOC(C=1C=CC=CC=1)(C=1C=CC=CC=1)C(C([O-])=O)OC1=NC(C)=CC(C)=N1 HTRPIHRNVLLBGC-UHFFFAOYSA-M 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Nanotechnology (AREA)
Physics & Mathematics (AREA)
Biomedical Technology (AREA)
Optics & Photonics (AREA)
Pulmonology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL00354991A 1999-10-26 2000-10-17 Sodium 2-(4,6-dimethyl-pyrimidin-2-yloxy)-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate and use thereof as endothelin antagonist PL354991A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19951617A DE19951617A1 (en)	1999-10-26	1999-10-26	Preparations of active pharmaceutical ingredients

Publications (1)

Publication Number	Publication Date
PL354991A1 true PL354991A1 (en)	2004-03-22

Family

ID=7926968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00354991A PL354991A1 (en)	1999-10-26	2000-10-17	Sodium 2-(4,6-dimethyl-pyrimidin-2-yloxy)-3-(2-(3,4-dimethoxyphenyl)ethoxy)-3,3-diphenylpropionate and use thereof as endothelin antagonist

Country Status (7)

Country	Link
EP (1)	EP1223960A2 (en)
JP (1)	JP2004500343A (en)
CN (1)	CN1384753A (en)
CA (1)	CA2388614A1 (en)
DE (1)	DE19951617A1 (en)
PL (1)	PL354991A1 (en)
WO (1)	WO2001030372A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7255877B2 (en)	1996-08-22	2007-08-14	Jagotec Ag	Fenofibrate microparticles
US6465016B2 (en) *	1996-08-22	2002-10-15	Research Triangle Pharmaceuticals	Cyclosporiine particles
US6979456B1 (en)	1998-04-01	2005-12-27	Jagotec Ag	Anticancer compositions
DE69912441T2 (en)	1998-08-19	2004-08-19	Skyepharma Canada Inc., Verdun	INJECTABLE AQUEOUS PROPOFOL DISPERSIONS
AR033711A1 (en) *	2001-05-09	2004-01-07	Novartis Ag	PHARMACEUTICAL COMPOSITIONS
DE102005026755A1 (en) *	2005-06-09	2006-12-14	Basf Ag	Production of solid solutions of sparingly soluble active ingredients by short-term overheating and rapid drying

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0816053B2 (en) *	1986-12-04	1996-02-21	大正製薬株式会社	Method of manufacturing patch
JPH0436237A (en) *	1990-06-01	1992-02-06	Taiho Yakuhin Kogyo Kk	Composite antitumor preparation
ES2085656T3 (en) *	1991-12-05	1996-06-01	Alfatec Pharma Gmbh	PERORAL ADMINISTRATION FOR PEPTIDIC MEDICINES, IN PARTICULAR INSULIN.
GB9325445D0 (en) *	1993-12-13	1994-02-16	Cortecs Ltd	Pharmaceutical formulations
JP4189044B2 (en) *	1997-07-01	2008-12-03	大正製薬株式会社	Multiple unit type sustained release tablets

1999
- 1999-10-26 DE DE19951617A patent/DE19951617A1/en not_active Withdrawn
2000
- 2000-10-17 WO PCT/EP2000/010205 patent/WO2001030372A2/en not_active Ceased
- 2000-10-17 JP JP2001532789A patent/JP2004500343A/en not_active Withdrawn
- 2000-10-17 CN CN00814940A patent/CN1384753A/en active Pending
- 2000-10-17 PL PL00354991A patent/PL354991A1/en unknown
- 2000-10-17 CA CA002388614A patent/CA2388614A1/en not_active Abandoned
- 2000-10-17 EP EP00972786A patent/EP1223960A2/en not_active Withdrawn

Also Published As

Publication number	Publication date
EP1223960A2 (en)	2002-07-24
JP2004500343A (en)	2004-01-08
CN1384753A (en)	2002-12-11
CA2388614A1 (en)	2001-05-03
WO2001030372A3 (en)	2001-11-01
DE19951617A1 (en)	2001-05-03
WO2001030372A2 (en)	2001-05-03

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