PL355470A1 - Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawanialeku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego - Google Patents

Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawanialeku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego

Info

Publication number: PL355470A1
Authority: PL; Poland
Prior art keywords: expected; place; application; active substance; equipment designed
Prior art date: 2002-08-13

Application number

PL02355470A

Other languages

English (en)

Other versions

PL205811B1 (pl

Inventor

Andrzej Lipkowski

Daniel Carr

Iwona Bonney

Dariusz Kosson

Aleksandra Misicka-Kęsik

Original Assignee

Andrzej Lipkowski

Daniel Carr

Iwona Bonney

Dariusz Kosson

Aleksandra Misicka-Kęsik

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-13

Filing date

2002-08-13

Publication date

2004-02-23

2002-08-13 Application filed by Andrzej Lipkowski, Daniel Carr, Iwona Bonney, Dariusz Kosson, Aleksandra Misicka-Kęsik filed Critical Andrzej Lipkowski

2002-08-13 Priority to PL355470A priority Critical patent/PL205811B1/pl

2003-08-07 Priority to PT03754322T priority patent/PT1529057E/pt

2003-08-07 Priority to PCT/PL2003/000077 priority patent/WO2004014943A2/en

2003-08-07 Priority to EP03754322A priority patent/EP1529057B1/en

2003-08-07 Priority to ES03754322T priority patent/ES2306885T3/es

2003-08-07 Priority to AT03754322T priority patent/ATE395354T1/de

2003-08-07 Priority to AU2003272160A priority patent/AU2003272160A1/en

2003-08-07 Priority to SI200331288T priority patent/SI1529057T1/sl

2003-08-07 Priority to DE60320999T priority patent/DE60320999D1/de

2003-08-07 Priority to DK03754322T priority patent/DK1529057T3/da

2003-08-07 Priority to US10/524,343 priority patent/US8084429B2/en

2004-02-23 Publication of PL355470A1 publication Critical patent/PL355470A1/pl

2008-08-13 Priority to CY20081100862T priority patent/CY1110890T1/el

2010-05-31 Publication of PL205811B1 publication Critical patent/PL205811B1/pl

Links

101500007657 Crotalus durissus terrificus Crotoxin chain gamma Proteins 0.000 title 1
239000013543 active substance Substances 0.000 title 1
239000003814 drug Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
125000000980 1H-indol-3-ylmethyl group Chemical group [H]C1=C([H])C([H])=C2N([H])C([H])=C(C([H])([H])[*])C2=C1[H] 0.000 abstract 1
DCXYFEDJOCDNAF-UWTATZPHSA-N D-Asparagine Chemical group OC(=O)[C@H](N)CC(N)=O DCXYFEDJOCDNAF-UWTATZPHSA-N 0.000 abstract 1
MTCFGRXMJLQNBG-UWTATZPHSA-N D-Serine Chemical group OC[C@@H](N)C(O)=O MTCFGRXMJLQNBG-UWTATZPHSA-N 0.000 abstract 1
229930195711 D-Serine Chemical group 0.000 abstract 1
125000000030 D-alanine group Chemical group [H]N([H])[C@](C([H])([H])[H])(C(=O)[*])[H] 0.000 abstract 1
QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 abstract 1
229930182846 D-asparagine Chemical group 0.000 abstract 1
125000003643 D-glutamine group Chemical group [H]N([H])[C@@]([H])(C(=O)[*])C([H])([H])C([H])([H])C(N([H])[H])=O 0.000 abstract 1
ROHFNLRQFUQHCH-RXMQYKEDSA-N D-leucine Chemical group CC(C)C[C@@H](N)C(O)=O ROHFNLRQFUQHCH-RXMQYKEDSA-N 0.000 abstract 1
229930182819 D-leucine Chemical group 0.000 abstract 1
FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical group CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 1
229930182818 D-methionine Chemical group 0.000 abstract 1
AYFVYJQAPQTCCC-STHAYSLISA-N D-threonine Chemical group C[C@H](O)[C@@H](N)C(O)=O AYFVYJQAPQTCCC-STHAYSLISA-N 0.000 abstract 1
229930182822 D-threonine Chemical group 0.000 abstract 1
239000000203 mixture Chemical group 0.000 abstract 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-QMMMGPOBSA-N phenylalanine group Chemical group N[C@@H](CC1=CC=CC=C1)C(=O)O COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Gastroenterology & Hepatology (AREA)
Animal Behavior & Ethology (AREA)
Zoology (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Neurology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

PL355470A 2002-08-13 2002-08-13 Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawania leku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego PL205811B1 (pl)

Priority Applications (12)

Application Number	Priority Date	Filing Date	Title
PL355470A PL205811B1 (pl)	2002-08-13	2002-08-13	Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawania leku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego
AT03754322T ATE395354T1 (de)	2002-08-13	2003-08-07	Derivate von biphalin und deren verwendung als analgetika
PCT/PL2003/000077 WO2004014943A2 (en)	2002-08-13	2003-08-07	Biphalin derivates and their analgesic applications
EP03754322A EP1529057B1 (en)	2002-08-13	2003-08-07	Biphalin derivatives and their analgesic applications
ES03754322T ES2306885T3 (es)	2002-08-13	2003-08-07	Derivados de bifalina y sus aplicaciones analgesicas.
PT03754322T PT1529057E (pt)	2002-08-13	2003-08-07	Derivados da bifalina e suas aplicações analgésicas
AU2003272160A AU2003272160A1 (en)	2002-08-13	2003-08-07	Biphalin derivates and their analgesic applications
SI200331288T SI1529057T1 (sl)	2002-08-13	2003-08-07	Derivati bifalina in analgetska uporaba le-teh
DE60320999T DE60320999D1 (de)	2002-08-13	2003-08-07	Derivate von biphalin und deren verwendung als analgetika
DK03754322T DK1529057T3 (da)	2002-08-13	2003-08-07	Derivat af biphalin og anvendelse heraf som analgetikum
US10/524,343 US8084429B2 (en)	2002-08-13	2003-08-07	Compounds and their analgesic applications
CY20081100862T CY1110890T1 (el)	2002-08-13	2008-08-13	Παραγωγα διφαλινης και οι αναλγητικες τους εφαρμογες

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PL355470A PL205811B1 (pl)	2002-08-13	2002-08-13	Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawania leku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego

Publications (2)

Publication Number	Publication Date
PL355470A1 true PL355470A1 (pl)	2004-02-23
PL205811B1 PL205811B1 (pl)	2010-05-31

Family

ID=31713224

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL355470A PL205811B1 (pl)	2002-08-13	2002-08-13	Zastosowanie peptydów o działaniu analgetycznym jako substancji czynnej w urządzeniach do podawania leku bezpośrednio do miejsca ich spodziewanego działania przeciwbólowego

Country Status (12)

Country	Link
US (1)	US8084429B2 (pl)
EP (1)	EP1529057B1 (pl)
AT (1)	ATE395354T1 (pl)
AU (1)	AU2003272160A1 (pl)
CY (1)	CY1110890T1 (pl)
DE (1)	DE60320999D1 (pl)
DK (1)	DK1529057T3 (pl)
ES (1)	ES2306885T3 (pl)
PL (1)	PL205811B1 (pl)
PT (1)	PT1529057E (pl)
SI (1)	SI1529057T1 (pl)
WO (1)	WO2004014943A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8026218B2 (en) *	2006-04-26	2011-09-27	The University Of Arizona	Bifunctional analgesic compounds for opioid receptor agonists and neurokinin-1 receptor antagonists
PL381925A1 (pl) *	2007-03-07	2008-09-15	Andrzej W. Lipkowski	Zastosowanie peptydu i przeciwbólowy środek farmaceutyczny
PL208164B1 (pl) *	2007-09-24	2011-03-31	Inst Medycyny Doświadczalnej I Klinicznej Pan Im M Mossakowskiego	Nowe peptydowe kompleksy platyny, sposób ich otrzymywania, kompozycja farmaceutyczna i zastosowanie
EP2350118B1 (en)	2008-09-19	2016-03-30	Nektar Therapeutics	Carbohydrate-based drug delivery polymers and conjugates thereof
DK2384334T3 (da) *	2008-12-31	2013-06-03	Action For Dev Of Resarch Sp Z O O	Fremgangsmåde til fremstilling af et hidtil ukendt opioidt peptid
WO2015127451A1 (en)	2014-02-24	2015-08-27	The Arizona Board Of Regents On Behalf Of The University Of Arizona	Multivalent/multifunctional ligands with agonist activities at opioid receptors and antagonist activities at nk1 receptor for relief of pain
PL422093A1 (pl) *	2017-07-03	2019-01-14	Uniwersytet Warszawski	Nowe peptydomimetyki hybrydowe do zastosowań w bólu neuropatycznym

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2032226A1 (en) *	1989-12-18	1991-06-19	Mark G. Bock	Benzodiazepine analogs
US5356902A (en) *	1992-11-06	1994-10-18	Eli Lilly And Company	Decahydroisoquinoline compounds as excitatory amino acid receptor antagonists
GB9426102D0 (en) *	1994-12-23	1995-02-22	Merck Sharp & Dohme	Pharmacuetical compositions

2002
- 2002-08-13 PL PL355470A patent/PL205811B1/pl unknown
2003
- 2003-08-07 DK DK03754322T patent/DK1529057T3/da active
- 2003-08-07 ES ES03754322T patent/ES2306885T3/es not_active Expired - Lifetime
- 2003-08-07 PT PT03754322T patent/PT1529057E/pt unknown
- 2003-08-07 AT AT03754322T patent/ATE395354T1/de active
- 2003-08-07 SI SI200331288T patent/SI1529057T1/sl unknown
- 2003-08-07 AU AU2003272160A patent/AU2003272160A1/en not_active Abandoned
- 2003-08-07 EP EP03754322A patent/EP1529057B1/en not_active Expired - Lifetime
- 2003-08-07 DE DE60320999T patent/DE60320999D1/de not_active Expired - Lifetime
- 2003-08-07 WO PCT/PL2003/000077 patent/WO2004014943A2/en not_active Ceased
- 2003-08-07 US US10/524,343 patent/US8084429B2/en not_active Expired - Fee Related
2008
- 2008-08-13 CY CY20081100862T patent/CY1110890T1/el unknown

Also Published As

Publication number	Publication date
DE60320999D1 (de)	2008-06-26
SI1529057T1 (sl)	2008-10-31
PT1529057E (pt)	2008-08-26
ATE395354T1 (de)	2008-05-15
AU2003272160A1 (en)	2004-02-25
US20060241053A1 (en)	2006-10-26
EP1529057B1 (en)	2008-05-14
EP1529057A2 (en)	2005-05-11
WO2004014943A2 (en)	2004-02-19
US8084429B2 (en)	2011-12-27
PL205811B1 (pl)	2010-05-31
DK1529057T3 (da)	2008-09-08
CY1110890T1 (el)	2015-06-10
ES2306885T3 (es)	2008-11-16
AU2003272160A8 (en)	2004-02-25
WO2004014943A3 (en)	2004-04-29

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