PL356404A1 - Pochodne dibenzo[b,f]azepiny oraz ich otrzymywanie - Google Patents

Pochodne dibenzo[b,f]azepiny oraz ich otrzymywanie

Info

Publication number: PL356404A1
Authority: PL; Poland
Prior art keywords: dibenzo; azepine; intermediates; azepine intermediates
Prior art date: 2000-02-07

Application number

PL01356404A

Other languages

English (en)

Other versions

PL214039B1 (pl

Inventor

Peter Funfschilling

Daniel Kaufmann

Olivier Lohse

Ulrich Beutler

Werner Zaugg

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-07

Filing date

2001-02-07

Publication date

2004-06-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9885081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL356404(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-02-07 Application filed by Novartis Ag filed Critical Novartis Ag

2004-06-28 Publication of PL356404A1 publication Critical patent/PL356404A1/pl

2013-06-28 Publication of PL214039B1 publication Critical patent/PL214039B1/pl

Links

XYOVOXDWRFGKEX-UHFFFAOYSA-N azepine Chemical compound N1C=CC=CC=C1 XYOVOXDWRFGKEX-UHFFFAOYSA-N 0.000 title 1
UZVGSSNIUNSOFA-UHFFFAOYSA-N dibenzofuran-1-carboxylic acid Chemical compound O1C2=CC=CC=C2C2=C1C=CC=C2C(=O)O UZVGSSNIUNSOFA-UHFFFAOYSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Epoxy Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

PL356404A 2000-02-07 2001-02-07 Sposób wytwarzania zwiazku pochodnego dibenzo[b,f]azepiny PL214039B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0002740.9A GB0002740D0 (en)	2000-02-07	2000-02-07	Organic compounds
PCT/EP2001/001330 WO2001056992A2 (en)	2000-02-07	2001-02-07	Dibenzo (b,f) azepine intermediates

Publications (2)

Publication Number	Publication Date
PL356404A1 true PL356404A1 (pl)	2004-06-28
PL214039B1 PL214039B1 (pl)	2013-06-28

Family

ID=9885081

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL356404A PL214039B1 (pl)	2000-02-07	2001-02-07	Sposób wytwarzania zwiazku pochodnego dibenzo[b,f]azepiny
PL392476A PL217225B1 (pl)	2000-02-07	2001-02-07	Związki pochodne dibenzo[b, f]azepiny oraz sposoby ich otrzymywania

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL392476A PL217225B1 (pl)	2000-02-07	2001-02-07	Związki pochodne dibenzo[b, f]azepiny oraz sposoby ich otrzymywania

Country Status (33)

Country	Link
US (1)	US7112673B2 (pl)
EP (2)	EP1265868B1 (pl)
JP (1)	JP4859322B2 (pl)
KR (5)	KR100931753B1 (pl)
CN (2)	CN1244563C (pl)
AR (2)	AR029442A1 (pl)
AT (2)	ATE505459T1 (pl)
AU (1)	AU767724B2 (pl)
BR (1)	BR0107922A (pl)
CA (3)	CA2639210C (pl)
CO (1)	CO5271705A1 (pl)
CY (1)	CY1111567T1 (pl)
CZ (1)	CZ301572B6 (pl)
DE (2)	DE60138271D1 (pl)
DK (1)	DK2067772T3 (pl)
ES (2)	ES2324900T3 (pl)
GB (1)	GB0002740D0 (pl)
HU (1)	HU229420B1 (pl)
IL (3)	IL150613A0 (pl)
MX (1)	MXPA02007629A (pl)
MY (1)	MY136474A (pl)
NO (1)	NO324949B1 (pl)
NZ (1)	NZ520329A (pl)
PE (1)	PE20011078A1 (pl)
PL (2)	PL214039B1 (pl)
PT (2)	PT2067772E (pl)
RU (1)	RU2303591C2 (pl)
SI (1)	SI2067772T1 (pl)
SK (1)	SK287217B6 (pl)
TR (1)	TR200201655T2 (pl)
TW (1)	TWI284638B (pl)
WO (1)	WO2001056992A2 (pl)
ZA (1)	ZA200206219B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6670472B2 (en)	2001-10-09	2003-12-30	Max India Limited	Process for the preparation of 10-methoxycarbamazepine
EP1302464A1 (en) *	2001-10-09	2003-04-16	Max India Limited	Process for preparation of 10-methoxycarbamazepine
CA2486560A1 (en)	2002-06-14	2003-12-24	Taro Pharmaceuticals U.S.A., Inc.	Method of preparing a 5h-dibenz[b,f]azepine-5-carboxamide
ITMI20040452A1 (it)	2004-03-09	2004-06-09	Clariant Lsm Italia Spa	Processo per la preparazione di oxcarbazepina
AP2007004244A0 (en)	2005-05-10	2007-12-31	Intermune Inc	Method of modulating stress-activated protein kinase system
ES2396051T3 (es) *	2006-04-26	2013-02-18	Supernus Pharmaceuticals, Inc.	Preparaciones de liberación controlada de oxcarbazepina que tienen perfil de liberación sigmoidal
US20090082335A1 (en) *	2007-09-26	2009-03-26	Protia, Llc	Deuterium-enriched oxcarbazepine
EP2296653B1 (en)	2008-06-03	2016-01-27	Intermune, Inc.	Compounds and methods for treating inflammatory and fibrotic disorders
IN2015DN02296A (pl)	2012-09-26	2015-08-21	Ranbaxy Lab Ltd
AR092742A1 (es)	2012-10-02	2015-04-29	Intermune Inc	Piridinonas antifibroticas
US11465978B2 (en)	2013-09-11	2022-10-11	The Administrators Of The Tulane Educational Fund	Anthranilic amides and the use thereof
RU2692485C2 (ru)	2014-04-02	2019-06-25	Интермьюн, Инк.	Противофиброзные пиридиноны

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4847374A (en) *	1987-01-27	1989-07-11	Ciba-Geigy Corporation	Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
DE4305502A1 (de) *	1993-02-23	1994-08-25	Basf Ag	Ortho-substituierte 2-Methoxyiminophenylessigsäuremethylamide
IT1272897B (it) *	1995-01-13	1997-07-01	I F C Iniziative Finanziaarie	Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
US6355680B1 (en) *	1996-02-20	2002-03-12	Exocell, Inc.	Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283594B1 (it)	1996-04-12	1998-04-22	Trifarma Srl	Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale
ATE344791T1 (de) *	1997-07-01	2006-11-15	Warner Lambert Co	2-(4-brom or 4-iod phenylamino)benzoesäurederivate und ihre anwendung als mek-inhibitoren
US6048856A (en)	1997-12-17	2000-04-11	Novo Nordisk A/S	Heterocyclic compounds

2000
- 2000-02-07 GB GBGB0002740.9A patent/GB0002740D0/en not_active Ceased
2001
- 2001-02-05 PE PE2001000121A patent/PE20011078A1/es not_active Application Discontinuation
- 2001-02-05 AR ARP010100515A patent/AR029442A1/es not_active Application Discontinuation
- 2001-02-06 MY MYPI20010513A patent/MY136474A/en unknown
- 2001-02-06 CO CO01008602A patent/CO5271705A1/es active IP Right Grant
- 2001-02-07 JP JP2001556842A patent/JP4859322B2/ja not_active Expired - Lifetime
- 2001-02-07 KR KR1020077029687A patent/KR100931753B1/ko not_active Expired - Fee Related
- 2001-02-07 ES ES01915203T patent/ES2324900T3/es not_active Expired - Lifetime
- 2001-02-07 CZ CZ20022676A patent/CZ301572B6/cs not_active IP Right Cessation
- 2001-02-07 DE DE60138271T patent/DE60138271D1/de not_active Expired - Lifetime
- 2001-02-07 CA CA2639210A patent/CA2639210C/en not_active Expired - Fee Related
- 2001-02-07 PT PT09153375T patent/PT2067772E/pt unknown
- 2001-02-07 KR KR1020107000738A patent/KR101216285B1/ko not_active Expired - Fee Related
- 2001-02-07 ES ES09153375T patent/ES2363490T3/es not_active Expired - Lifetime
- 2001-02-07 WO PCT/EP2001/001330 patent/WO2001056992A2/en not_active Ceased
- 2001-02-07 BR BR0107922-0A patent/BR0107922A/pt not_active Application Discontinuation
- 2001-02-07 IL IL15061301A patent/IL150613A0/xx unknown
- 2001-02-07 AU AU42373/01A patent/AU767724B2/en not_active Ceased
- 2001-02-07 EP EP01915203A patent/EP1265868B1/en not_active Expired - Lifetime
- 2001-02-07 KR KR1020097019039A patent/KR100966209B1/ko not_active Expired - Fee Related
- 2001-02-07 DE DE60144456T patent/DE60144456D1/de not_active Expired - Lifetime
- 2001-02-07 MX MXPA02007629A patent/MXPA02007629A/es active IP Right Grant
- 2001-02-07 SK SK1126-2002A patent/SK287217B6/sk not_active IP Right Cessation
- 2001-02-07 PL PL356404A patent/PL214039B1/pl unknown
- 2001-02-07 CN CNB018035302A patent/CN1244563C/zh not_active Expired - Lifetime
- 2001-02-07 US US10/182,980 patent/US7112673B2/en not_active Expired - Lifetime
- 2001-02-07 TR TR2002/01655T patent/TR200201655T2/xx unknown
- 2001-02-07 NZ NZ520329A patent/NZ520329A/en not_active IP Right Cessation
- 2001-02-07 EP EP09153375A patent/EP2067772B1/en not_active Expired - Lifetime
- 2001-02-07 KR KR1020087027467A patent/KR20080103608A/ko not_active Ceased
- 2001-02-07 AT AT09153375T patent/ATE505459T1/de active
- 2001-02-07 CA CA002395601A patent/CA2395601C/en not_active Expired - Fee Related
- 2001-02-07 CN CNB2005100853024A patent/CN100455572C/zh not_active Expired - Lifetime
- 2001-02-07 CA CA2724295A patent/CA2724295C/en not_active Expired - Fee Related
- 2001-02-07 PL PL392476A patent/PL217225B1/pl unknown
- 2001-02-07 SI SI200130996T patent/SI2067772T1/sl unknown
- 2001-02-07 HU HU0300243A patent/HU229420B1/hu unknown
- 2001-02-07 DK DK09153375.2T patent/DK2067772T3/da active
- 2001-02-07 KR KR1020027010123A patent/KR20020071033A/ko not_active Ceased
- 2001-02-07 PT PT01915203T patent/PT1265868E/pt unknown
- 2001-02-07 RU RU2002123334/04A patent/RU2303591C2/ru not_active IP Right Cessation
- 2001-02-07 AT AT01915203T patent/ATE427938T1/de active
- 2001-02-09 TW TW090102908A patent/TWI284638B/zh not_active IP Right Cessation
2002
- 2002-07-04 IL IL150613A patent/IL150613A/en not_active IP Right Cessation
- 2002-07-26 NO NO20023575A patent/NO324949B1/no not_active IP Right Cessation
- 2002-08-05 ZA ZA200206219A patent/ZA200206219B/en unknown
2007
- 2007-12-17 IL IL188183A patent/IL188183A/en not_active IP Right Cessation
2010
- 2010-12-01 AR ARP100104442A patent/AR079237A2/es unknown
2011
- 2011-06-16 CY CY20111100572T patent/CY1111567T1/el unknown

Also Published As

Publication number	Publication date
PL392476A1 (pl)	2010-11-22
PT1265868E (pt)	2009-07-15
TWI284638B (en)	2007-08-01
CN1394204A (zh)	2003-01-29
DK2067772T3 (da)	2011-07-18
ZA200206219B (en)	2003-04-04
KR20090102882A (ko)	2009-09-30
CN1244563C (zh)	2006-03-08
AU767724B2 (en)	2003-11-20
KR100931753B1 (ko)	2009-12-14
GB0002740D0 (en)	2000-03-29
HK1052501A1 (en)	2003-09-19
CA2395601C (en)	2010-01-05
KR20100018069A (ko)	2010-02-16
HUP0300243A3 (en)	2005-07-28
NO324949B1 (no)	2008-01-14
SK287217B6 (sk)	2010-03-08
CY1111567T1 (el)	2015-10-07
EP2067772A2 (en)	2009-06-10
EP1265868A2 (en)	2002-12-18
AR029442A1 (es)	2003-06-25
BR0107922A (pt)	2002-10-22
CZ301572B6 (cs)	2010-04-21
HU229420B1 (en)	2013-12-30
NZ520329A (en)	2003-11-28
IL150613A (en)	2010-05-17
HUP0300243A2 (hu)	2003-06-28
AU4237301A (en)	2001-08-14
PT2067772E (pt)	2011-07-13
KR101216285B1 (ko)	2012-12-28
IL188183A (en)	2011-02-28
EP1265868B1 (en)	2009-04-08
KR20080003016A (ko)	2008-01-04
EP2067772B1 (en)	2011-04-13
IL150613A0 (en)	2003-02-12
KR20080103608A (ko)	2008-11-27
NO20023575D0 (no)	2002-07-26
CZ20022676A3 (cs)	2002-11-13
DE60144456D1 (de)	2011-05-26
NO20023575L (no)	2002-07-26
US7112673B2 (en)	2006-09-26
US20030032800A1 (en)	2003-02-13
CA2639210A1 (en)	2001-08-09
AR079237A2 (es)	2012-01-04
MY136474A (en)	2008-10-31
PL217225B1 (pl)	2014-06-30
ATE427938T1 (de)	2009-04-15
KR100966209B1 (ko)	2010-06-25
MXPA02007629A (es)	2002-12-13
CA2724295A1 (en)	2001-08-09
ATE505459T1 (de)	2011-04-15
CO5271705A1 (es)	2003-04-30
JP2003521536A (ja)	2003-07-15
CA2724295C (en)	2011-07-26
RU2002123334A (ru)	2004-01-10
CA2639210C (en)	2011-05-03
SK11262002A3 (sk)	2003-02-04
CN100455572C (zh)	2009-01-28
PL214039B1 (pl)	2013-06-28
WO2001056992A2 (en)	2001-08-09
CN1721409A (zh)	2006-01-18
RU2303591C2 (ru)	2007-07-27
PE20011078A1 (es)	2001-11-16
KR20020071033A (ko)	2002-09-11
CA2395601A1 (en)	2001-08-09
EP2067772A3 (en)	2009-08-19
DE60138271D1 (de)	2009-05-20
ES2363490T3 (es)	2011-08-05
TR200201655T2 (tr)	2002-11-21
ES2324900T3 (es)	2009-08-19
WO2001056992A3 (en)	2002-01-24
JP4859322B2 (ja)	2012-01-25
SI2067772T1 (sl)	2011-08-31

Publication	Publication Date	Title
MXPA03004292A (es)	2004-02-12	Compuesto de lactama.
GB0107619D0 (en)	2001-05-16	Inket Printer
AU143419S (en)	2001-04-06	Printer
ZA200205479B (en)	2003-12-31	Novel biarylcarboxamides.
AU143418S (en)	2001-04-06	Printer
GB2364915B (en)	2004-02-04	Hyperpharyngeal tube
AU143417S (en)	2001-04-06	Printer
EP1344142A4 (en)	2005-10-26	REMOTE PRINTING
EP1338426A4 (en)	2005-08-17	PRINTER
GB2358986B (en)	2004-03-10	Simple supplementary service protocol
IL150613A0 (en)	2003-02-12	Dibenzo (b,f) azepine intermediates
MXPA03001991A (es)	2003-06-24	Novedosas arilalcano-sulfonamidas.
GB0108230D0 (en)	2001-05-23	Printer
GB0011917D0 (en)	2000-07-05	Printing
AU4831301A (en)	2001-08-27	Gm-negative ehv-mutants
GB2363887B (en)	2004-02-11	Mailer-postal service interfaces
GB0018864D0 (en)	2000-09-20	Traffic mediator
AU145684S (en)	2001-10-25	Ring
MXPA03001773A (es)	2003-06-04	Tienopirimidinas.
GB0007229D0 (en)	2000-05-17	Novel catalysts
TW419954U (en)	2001-01-21	Dual changing type shoe-pad
MX231964B (es)	2005-11-09	Poliamidas.
CA90477S (en)	2000-09-29	Fork
CA89803S (en)	2000-06-30	Fork
AU145568S (en)	2001-10-10	Tube