PL356769A1 - Nowe związki heterocykliczne oraz ich sole i ich zastosowanie medyczne - Google Patents

Nowe związki heterocykliczne oraz ich sole i ich zastosowanie medyczne

Info

Publication number
PL356769A1
PL356769A1 PL00356769A PL35676900A PL356769A1 PL 356769 A1 PL356769 A1 PL 356769A1 PL 00356769 A PL00356769 A PL 00356769A PL 35676900 A PL35676900 A PL 35676900A PL 356769 A1 PL356769 A1 PL 356769A1
Authority
PL
Poland
Prior art keywords
salts
same
heterocyclic compounds
medicinal use
novel heterocyclic
Prior art date
Application number
PL00356769A
Other languages
English (en)
Inventor
Hiroshi Matsui
Hideo Kobayashi
Satoru Azukizawa
Masayasu Kasai
Akihisa Yoshimi
Hiroaki Shirahase
Original Assignee
Kyoto Pharmaceutical Industries, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Pharmaceutical Industries, Ltd. filed Critical Kyoto Pharmaceutical Industries, Ltd.
Publication of PL356769A1 publication Critical patent/PL356769A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL00356769A 1999-12-03 2000-11-29 Nowe związki heterocykliczne oraz ich sole i ich zastosowanie medyczne PL356769A1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP34554399 1999-12-03
JP2000295108 2000-09-27
PCT/JP2000/008464 WO2001040192A1 (en) 1999-12-03 2000-11-29 Novel heterocyclic compounds and salts thereof and medicinal use of the same

Publications (1)

Publication Number Publication Date
PL356769A1 true PL356769A1 (pl) 2004-07-12

Family

ID=26578048

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00356769A PL356769A1 (pl) 1999-12-03 2000-11-29 Nowe związki heterocykliczne oraz ich sole i ich zastosowanie medyczne

Country Status (20)

Country Link
US (1) US6589963B2 (pl)
EP (1) EP1236719A4 (pl)
KR (1) KR100716525B1 (pl)
CN (1) CN1215059C (pl)
AR (1) AR033349A1 (pl)
AU (1) AU782631C (pl)
BR (1) BR0016064A (pl)
CA (1) CA2393265A1 (pl)
CO (1) CO5440230A1 (pl)
CZ (1) CZ20021911A3 (pl)
HU (1) HUP0203431A3 (pl)
IL (2) IL149883A0 (pl)
MX (1) MXPA02005528A (pl)
NO (1) NO323922B1 (pl)
NZ (1) NZ519592A (pl)
PL (1) PL356769A1 (pl)
RU (1) RU2256661C2 (pl)
TW (1) TWI286549B (pl)
WO (1) WO2001040192A1 (pl)
YU (1) YU50302A (pl)

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US6455734B1 (en) * 2000-08-09 2002-09-24 Magnesium Diagnostics, Inc. Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
EP1911462A3 (en) 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
HU230253B1 (hu) 2001-01-26 2015-11-30 Merck Sharp & Dohme Corp Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
DK1355644T3 (da) 2001-01-26 2006-10-23 Schering Corp Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
JP4279136B2 (ja) 2001-05-29 2009-06-17 京都薬品工業株式会社 新規複素環化合物およびその医薬用途
PL367676A1 (pl) * 2001-05-29 2005-03-07 Kyoto Pharmaceutical Industries, Ltd. Nowe pochodne heterocykliczne i ich zastosowanie w medycynie
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング　コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
WO2003059907A1 (en) * 2002-01-17 2003-07-24 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
DE10222034A1 (de) * 2002-05-17 2003-11-27 Bayer Ag Tetrahydroisochinolin-Derivate
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
PA8594401A1 (es) * 2003-02-21 2004-09-16 Pfizer Acidos carboxilicos de heteroarilo condensado como agonista del ppar
JP4589919B2 (ja) 2003-03-07 2010-12-01 シェーリング コーポレイション 高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング　コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
CA2517571C (en) 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CN1300115C (zh) * 2004-03-26 2007-02-14 厦门大学 一种合成1，2，3，4－四氢异喹啉衍生物的方法
CA2585172C (en) 2004-10-29 2014-08-12 Kalypsys, Inc. Sulfonyl-substituted bicyclic compounds as modulators of ppar
AU2006277742B2 (en) * 2005-08-08 2010-08-26 Pfizer Inc. Salts and polymorphs of a VEGF-R inhibitor
WO2007030559A2 (en) * 2005-09-07 2007-03-15 Plexxikon, Inc. 1, 3-disubstituted indole derivatives for use as ppar modulators
US7790745B2 (en) 2005-10-21 2010-09-07 Bristol-Myers Squibb Company Tetrahydroisoquinoline LXR Modulators
HUE040020T2 (hu) * 2005-10-25 2019-02-28 Kalypsys Inc PPAR modulátorok sói és eljárások metabolikus betegségek kezelésére
EP1790646A1 (fr) * 2005-11-24 2007-05-30 Sanofi-Aventis Derives de Isoquinoline et Benzo[h]Isoquinoline, leur preparation et leur utilisation en thérapeutique en tant qu'antagonistes du recepteur de l'histamine H3.
WO2008091863A1 (en) 2007-01-23 2008-07-31 Kalypsys, Inc. Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis
US20080186971A1 (en) * 2007-02-02 2008-08-07 Tarari, Inc. Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic
WO2009019598A2 (en) * 2007-08-03 2009-02-12 Dr. Reddy's Laboratories Ltd. Inhalation therapy for respiratory disorders
EA018225B1 (ru) * 2008-03-07 2013-06-28 Транстек Фарма, Инк. Соединения оксадиазоантрацена для лечения диабета
AR080375A1 (es) 2010-03-05 2012-04-04 Sanofi Aventis Procedimiento para la preparacion de 2-(cicloheximetil)-n-{2-[(2s)-1-metilpirrolidin-2-il] etil}-1,2,3,4-tetrahidroisoquinolina- 7-sulfonamida
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
WO2012033195A1 (ja) * 2010-09-10 2012-03-15 京都薬品工業株式会社 複素環化合物
CN102807526B (zh) * 2011-06-21 2015-12-02 寿光富康制药有限公司 组蛋白去乙酰化酶抑制剂ZYJ-D08a及其差向异构体的制备方法与应用
CN102702098A (zh) * 2012-05-24 2012-10-03 盛世泰科生物医药技术(苏州)有限公司 6-甲氧基-1,2,3,4四氢喹啉-5羧酸甲酯的合成
AR101196A1 (es) * 2014-07-16 2016-11-30 Gruenenthal Gmbh Compuestos de pirimidina sustituidos
US20240041899A1 (en) * 2020-12-18 2024-02-08 Aska Pharmaceutical Co., Ltd. Solid preparation

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JPS6051189A (ja) 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
AR240698A1 (es) 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales
EP0842925A1 (en) 1987-09-04 1998-05-20 Beecham Group Plc Substituted thiazolidinedione derivatives
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
CA2259487A1 (en) * 1996-07-01 1998-01-08 Margaret Mary Faul Hypoglycemic and hypolipidemic compounds
CA2259431A1 (en) * 1996-07-01 1998-01-08 Eli Lilly And Company Hypoglycemic and hypolipidemic compounds

Also Published As

Publication number Publication date
AU1649501A (en) 2001-06-12
YU50302A (sh) 2006-01-16
KR20020058079A (ko) 2002-07-12
KR100716525B1 (ko) 2007-05-10
NO20022600D0 (no) 2002-05-31
WO2001040192A1 (en) 2001-06-07
NO20022600L (no) 2002-08-05
NZ519592A (en) 2003-11-28
CZ20021911A3 (cs) 2002-10-16
HUP0203431A3 (en) 2003-11-28
AU782631C (en) 2006-08-17
IL149883A (en) 2007-03-08
US20030027836A1 (en) 2003-02-06
MXPA02005528A (es) 2002-09-02
CO5440230A1 (es) 2004-09-30
BR0016064A (pt) 2004-07-27
CN1215059C (zh) 2005-08-17
AU782631B2 (en) 2005-08-18
CN1402712A (zh) 2003-03-12
IL149883A0 (en) 2002-11-10
EP1236719A1 (en) 2002-09-04
AR033349A1 (es) 2003-12-17
HK1053657A1 (en) 2003-10-31
HUP0203431A2 (hu) 2003-02-28
US6589963B2 (en) 2003-07-08
CA2393265A1 (en) 2001-06-07
RU2256661C2 (ru) 2005-07-20
TWI286549B (en) 2007-09-11
EP1236719A4 (en) 2003-06-25
NO323922B1 (no) 2007-07-23

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)