PL358811A1 - Wysokouporządkowane struktury oparte o kwasy nukleinowe - Google Patents

Wysokouporządkowane struktury oparte o kwasy nukleinowe

Info

Publication number
PL358811A1
PL358811A1 PL00358811A PL35881100A PL358811A1 PL 358811 A1 PL358811 A1 PL 358811A1 PL 00358811 A PL00358811 A PL 00358811A PL 35881100 A PL35881100 A PL 35881100A PL 358811 A1 PL358811 A1 PL 358811A1
Authority
PL
Poland
Prior art keywords
nucleic acid
high order
acid based
based structures
order nucleic
Prior art date
Application number
PL00358811A
Other languages
English (en)
Inventor
Frank J. Carr
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9926810.4A external-priority patent/GB9926810D0/en
Priority claimed from GB0011126A external-priority patent/GB0011126D0/en
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL358811A1 publication Critical patent/PL358811A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
    • C12N2310/151—Nucleic acids forming more than 2 strands, e.g. TFOs more than 3 strands, e.g. tetrads, H-DNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/52—Physical structure branched

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL00358811A 1999-11-13 2000-11-13 Wysokouporządkowane struktury oparte o kwasy nukleinowe PL358811A1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9926810.4A GB9926810D0 (en) 1999-11-13 1999-11-13 High order nucleic acid-based structures
GB0011126A GB0011126D0 (en) 2000-05-10 2000-05-10 High order nucleic acid-based structures
PCT/EP2000/011197 WO2001036624A1 (en) 1999-11-13 2000-11-13 High order nucleic acid based structures

Publications (1)

Publication Number Publication Date
PL358811A1 true PL358811A1 (pl) 2004-08-23

Family

ID=26244234

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00358811A PL358811A1 (pl) 1999-11-13 2000-11-13 Wysokouporządkowane struktury oparte o kwasy nukleinowe

Country Status (16)

Country Link
EP (1) EP1228201A1 (pl)
JP (1) JP2003522524A (pl)
KR (1) KR20020059727A (pl)
CN (1) CN1390253A (pl)
AU (1) AU782880B2 (pl)
BR (1) BR0015484A (pl)
CA (1) CA2391084A1 (pl)
CZ (1) CZ20021472A3 (pl)
HK (1) HK1052529A1 (pl)
HU (1) HUP0203914A2 (pl)
MX (1) MXPA02004727A (pl)
NO (1) NO20022231D0 (pl)
PL (1) PL358811A1 (pl)
RU (1) RU2002113755A (pl)
SK (1) SK6042002A3 (pl)
WO (1) WO2001036624A1 (pl)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
EP1411770A4 (en) 2001-07-05 2006-05-10 Chiron Corp POLYNUCLEOTIDES CODING FOR ANTIGENIC C-TYPE HIV POLYPEPTIDES, POLYPEPTIDES AND THEIR USE
JP2014525921A (ja) * 2011-08-05 2014-10-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 核酸ナノテクノロジー及びマイクロテクノロジーに関する組成物及び方法
WO2014018675A1 (en) 2012-07-24 2014-01-30 President And Fellows Of Harvard College Self-assembly of nucleic acid nanostructures
WO2014074597A1 (en) 2012-11-06 2014-05-15 President And Fellows Of Harvard College Compositions and methods relating to complex nucleic acid nanostructures
WO2015070080A2 (en) * 2013-11-08 2015-05-14 Dana-Farber Cancer Institute, Inc. Nucleic acid nanostructures for in vivo agent delivery
JP2017523594A (ja) 2014-05-22 2017-08-17 プレジデント アンド フェローズ オブ ハーバード カレッジ スケーラブルな核酸をベースにしたナノファブリケーション
EP3426598B1 (en) 2016-03-11 2021-07-28 Children's Medical Center Corporation Nucleic acid nanoswitch catenanes
EP3494124B1 (en) 2016-08-02 2022-03-09 President and Fellows of Harvard College Crisscross cooperative self-assembly
CN110711254B (zh) * 2018-07-12 2022-07-26 百药智达（北京）纳米生物技术有限公司 核酸纳米颗粒及包含其的药物组合物
TWI743518B (zh) * 2018-07-12 2021-10-21 大陸商百藥智達（北京）納米生物技術有限公司 核酸奈米顆粒、包含其的藥物組合物、含阿霉素的藥物及其製備方法
CN110960534B (zh) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 含五氟尿嘧啶的药物、其制备方法、药物组合物及其应用
CN110960536B (zh) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 含阿司匹林的药物、其制备方法、药物组合物及应用
CN110960530B (zh) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 含他克林的药物、其制备方法、药物组合物及其应用
CN110960542B (zh) * 2018-09-30 2022-07-26 百药智达（北京）纳米生物技术有限公司 含吡柔比星的药物、其制备方法、药物组合物及其应用
CN110960690B (zh) * 2018-09-30 2022-07-22 百药智达（北京）纳米生物技术有限公司 含表柔比星的药物、其制备方法、药物组合物及其应用
CN111053765B (zh) * 2018-10-16 2022-07-26 百药智达（北京）纳米生物技术有限公司 含紫杉醇的药物、其制备方法、药物组合物及应用
CN111068065B (zh) * 2018-10-22 2022-07-26 百药智达（北京）纳米生物技术有限公司 含奥沙利铂的药物、其制备方法、药物组合物及其应用
CN111084887B (zh) * 2018-10-23 2022-07-22 百药智达（北京）纳米生物技术有限公司 含黄酮的药物、其制备方法、药物组合物及应用
CN111096965B (zh) * 2018-10-29 2022-07-26 百药智达（北京）纳米生物技术有限公司 含双氢青蒿素的药物、其制备方法、药物组合物及其应用
US12268748B2 (en) 2019-04-10 2025-04-08 President And Fellows Of Harvard College Nucleic acid nanostructures crosslinked with oligolysine
WO2020247724A1 (en) 2019-06-07 2020-12-10 Dana-Farber Cancer Institute, Inc. Dna nanostructure-based vaccines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151631A1 (en) * 1983-08-03 1985-08-21 The Research Foundation Of State University Of New York Nucleic acid branched junctions with precisely defined migrational mobility
US5386020A (en) * 1991-01-10 1995-01-31 New York University Multiply connected, three-dimensional nucleic acid structures
US5278051A (en) * 1991-12-12 1994-01-11 New York University Construction of geometrical objects from polynucleotides
US6072044A (en) * 1996-04-26 2000-06-06 New York University Nanoconstructions of geometrical objects and lattices from antiparallel nucleic acid double crossover molecules

Also Published As

Publication number Publication date
KR20020059727A (ko) 2002-07-13
SK6042002A3 (en) 2002-12-03
WO2001036624A1 (en) 2001-05-25
CN1390253A (zh) 2003-01-08
BR0015484A (pt) 2002-07-02
AU782880B2 (en) 2005-09-08
EP1228201A1 (en) 2002-08-07
HUP0203914A2 (en) 2003-03-28
MXPA02004727A (es) 2002-08-30
AU2000101A (en) 2001-05-30
CZ20021472A3 (cs) 2002-07-17
RU2002113755A (ru) 2004-01-10
HK1052529A1 (zh) 2003-09-19
NO20022231L (no) 2002-05-10
JP2003522524A (ja) 2003-07-29
CA2391084A1 (en) 2001-05-25
NO20022231D0 (no) 2002-05-10

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)