PL358912A1 - Sposób fermentacyjnego wytwarzania L-aminokwasów przez wzmocnienie genu gnd - Google Patents
Sposób fermentacyjnego wytwarzania L-aminokwasów przez wzmocnienie genu gndInfo
- Publication number
- PL358912A1 PL358912A1 PL00358912A PL35891200A PL358912A1 PL 358912 A1 PL358912 A1 PL 358912A1 PL 00358912 A PL00358912 A PL 00358912A PL 35891200 A PL35891200 A PL 35891200A PL 358912 A1 PL358912 A1 PL 358912A1
- Authority
- PL
- Poland
- Prior art keywords
- amino acid
- amino acids
- amplification
- bacteria
- fermentative preparation
- Prior art date
Links
- 150000008575 L-amino acids Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 230000003321 amplification Effects 0.000 title 1
- 101150014950 gnd gene Proteins 0.000 title 1
- 238000003199 nucleic acid amplification method Methods 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108020001657 6-phosphogluconate dehydrogenase Proteins 0.000 abstract 1
- 102000004567 6-phosphogluconate dehydrogenase Human genes 0.000 abstract 1
- 241000186031 Corynebacteriaceae Species 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- 229930182844 L-isoleucine Natural products 0.000 abstract 1
- 108010042687 Pyruvate Oxidase Proteins 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 abstract 1
- 229960002898 threonine Drugs 0.000 abstract 1
- 229960004799 tryptophan Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53126500A | 2000-03-20 | 2000-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL358912A1 true PL358912A1 (pl) | 2004-08-23 |
Family
ID=24116938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL00358912A PL358912A1 (pl) | 2000-03-20 | 2000-07-05 | Sposób fermentacyjnego wytwarzania L-aminokwasów przez wzmocnienie genu gnd |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20030119154A1 (pl) |
| EP (1) | EP1179076B9 (pl) |
| KR (1) | KR100826815B1 (pl) |
| CN (1) | CN1350586A (pl) |
| AT (1) | ATE292687T1 (pl) |
| AU (1) | AU6431600A (pl) |
| BR (1) | BR0010817A (pl) |
| CA (1) | CA2374265A1 (pl) |
| DE (1) | DE60019280T2 (pl) |
| ES (1) | ES2240135T3 (pl) |
| MX (1) | MXPA01011643A (pl) |
| PL (1) | PL358912A1 (pl) |
| SK (1) | SK16542001A3 (pl) |
| WO (1) | WO2001071012A1 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002215910A1 (en) * | 2000-11-04 | 2002-05-15 | Degussa Ag | Process for the fermentative preparation of l-amino acids using strains of the enterobacteriaceae family |
| US20030017554A1 (en) * | 2000-11-15 | 2003-01-23 | Mechthild Rieping | Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family |
| DE10210527A1 (de) | 2002-03-09 | 2003-09-18 | Degussa | Allele des aceA-Gens aus coryneformen Bakterien |
| EP1748062B1 (en) * | 2004-05-20 | 2012-06-13 | Ajinomoto Co., Inc. | Succinic acid-producing bacterium and process for producing succinic acid |
| DE102005032426A1 (de) | 2004-12-18 | 2006-06-22 | Degussa Ag | Allele des gnd-Gens aus coryneformen Bakterien |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| KR101335853B1 (ko) | 2011-12-01 | 2013-12-02 | 씨제이제일제당 (주) | L-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 l-아미노산 및 리보플라빈을 생산하는 방법 |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN105602966B (zh) * | 2016-01-08 | 2019-03-15 | 广西大学 | 一种编码6-磷酸葡萄糖酸脱氢酶的基因及其应用 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN114729339B (zh) * | 2021-01-29 | 2023-01-03 | Cj第一制糖株式会社 | 新真菌硫酮还原酶变体及使用其生产l-赖氨酸的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2165546B (en) * | 1984-08-21 | 1989-05-17 | Asahi Chemical Ind | A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom |
| GB2223754B (en) * | 1988-09-12 | 1992-07-22 | Degussa | Dna encoding phosphoenolpyruvate carboxylase |
| DE3943117A1 (de) * | 1989-12-27 | 1991-07-04 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna |
| DE4027453A1 (de) * | 1990-08-30 | 1992-03-05 | Degussa | Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren |
| CA2175042C (en) * | 1993-10-28 | 2002-05-28 | Hiroyuki Kojima | Method for production of substances using microorganisms with an increased productivity for nadph |
| JPH09224662A (ja) * | 1996-02-23 | 1997-09-02 | Mitsubishi Chem Corp | 6−ホスホグルコン酸デヒドロゲナーゼおよびそれをコードするdna |
| DE60030400T2 (de) * | 1999-07-09 | 2007-09-13 | Degussa Gmbh | Für den opac-gen kodierende nukleotidsequenzen |
| EP1208205B1 (en) * | 1999-07-23 | 2006-09-27 | Archer-Daniels-Midland Company | Methods for producing l-amino acids by increasing cellular nadph |
-
2000
- 2000-07-05 AU AU64316/00A patent/AU6431600A/en not_active Abandoned
- 2000-07-05 CA CA002374265A patent/CA2374265A1/en not_active Abandoned
- 2000-07-05 EP EP00951336A patent/EP1179076B9/en not_active Expired - Lifetime
- 2000-07-05 SK SK1654-2001A patent/SK16542001A3/sk unknown
- 2000-07-05 ES ES00951336T patent/ES2240135T3/es not_active Expired - Lifetime
- 2000-07-05 WO PCT/EP2000/006299 patent/WO2001071012A1/en not_active Ceased
- 2000-07-05 CN CN00807548A patent/CN1350586A/zh active Pending
- 2000-07-05 AT AT00951336T patent/ATE292687T1/de not_active IP Right Cessation
- 2000-07-05 KR KR1020017014821A patent/KR100826815B1/ko not_active Expired - Fee Related
- 2000-07-05 DE DE60019280T patent/DE60019280T2/de not_active Expired - Lifetime
- 2000-07-05 BR BR0010817-0A patent/BR0010817A/pt not_active Application Discontinuation
- 2000-07-05 PL PL00358912A patent/PL358912A1/pl not_active Application Discontinuation
- 2000-07-05 MX MXPA01011643A patent/MXPA01011643A/es unknown
-
2002
- 2002-02-20 US US10/078,167 patent/US20030119154A1/en not_active Abandoned
-
2003
- 2003-10-17 US US10/686,736 patent/US20040063181A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1179076B1 (en) | 2005-04-06 |
| DE60019280D1 (de) | 2005-05-12 |
| US20040063181A1 (en) | 2004-04-01 |
| KR20010113832A (ko) | 2001-12-28 |
| ES2240135T3 (es) | 2005-10-16 |
| MXPA01011643A (es) | 2003-02-27 |
| EP1179076B9 (en) | 2005-11-30 |
| AU6431600A (en) | 2001-10-03 |
| DE60019280T2 (de) | 2006-05-11 |
| CA2374265A1 (en) | 2001-09-27 |
| ATE292687T1 (de) | 2005-04-15 |
| EP1179076A1 (en) | 2002-02-13 |
| CN1350586A (zh) | 2002-05-22 |
| US20030119154A1 (en) | 2003-06-26 |
| SK16542001A3 (sk) | 2002-07-02 |
| WO2001071012A1 (en) | 2001-09-27 |
| KR100826815B1 (ko) | 2008-05-02 |
| BR0010817A (pt) | 2002-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |