PL360850A1 - Zastosowanie egzogennego szczepu bakterii kwasu mlekowego w zwalczaniu chorób wywoływanych przez bakterie Actinomyces naeslundii - Google Patents

Zastosowanie egzogennego szczepu bakterii kwasu mlekowego w zwalczaniu chorób wywoływanych przez bakterie Actinomyces naeslundii

Info

Publication number
PL360850A1
PL360850A1 PL36085001A PL36085001A PL360850A1 PL 360850 A1 PL360850 A1 PL 360850A1 PL 36085001 A PL36085001 A PL 36085001A PL 36085001 A PL36085001 A PL 36085001A PL 360850 A1 PL360850 A1 PL 360850A1
Authority
PL
Poland
Prior art keywords
bacteria strain
lactic bacteria
actinomyces naeslundii
strain against
exogenous
Prior art date
Application number
PL36085001A
Other languages
English (en)
Other versions
PL202576B1 (pl
Inventor
Elena-Maria Comelli
Bernhard Guggenheim
Jean-Richard Neeser
Francesca Stingele
Original Assignee
Societe Des Produits Nestle S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Des Produits Nestle S.A. filed Critical Societe Des Produits Nestle S.A.
Publication of PL360850A1 publication Critical patent/PL360850A1/pl
Publication of PL202576B1 publication Critical patent/PL202576B1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G4/123Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1236Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt using Leuconostoc, Pediococcus or Streptococcus sp. other than Streptococcus Thermophilus; Artificial sour buttermilk in general
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/123Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
    • A23C9/1238Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt using specific L. bulgaricus or S. thermophilus microorganisms; using entrapped or encapsulated yoghurt bacteria; Physical or chemical treatment of L. bulgaricus or S. thermophilus cultures; Fermentation only with L. bulgaricus or only with S. thermophilus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K40/00Shaping or working-up of animal feeding-stuffs
    • A23K40/30Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C2220/00Biochemical treatment
    • A23C2220/20Treatment with microorganisms
    • A23C2220/206Slime forming bacteria; Exopolysaccharide or thickener producing bacteria, ropy cultures, so-called filant strains
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2400/00Lactic or propionic acid bacteria
    • A23V2400/21Streptococcus, lactococcus
    • A23V2400/249Thermophilus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/885Streptococcus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL360850A 2000-06-02 2001-05-30 Zastosowanie szczepu bakterii kwasu mlekowego i zawierająca go kompozycja PL202576B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00201948A EP1159951A1 (en) 2000-06-02 2000-06-02 Use of exogenous lactic bacteria strain against Actinomyces naeslundii-related diseases
PCT/EP2001/006268 WO2001091711A1 (en) 2000-06-02 2001-05-30 Use of exogenous lactic bacteria strain against actinomyces naeslundii related diseases

Publications (2)

Publication Number Publication Date
PL360850A1 true PL360850A1 (pl) 2004-09-20
PL202576B1 PL202576B1 (pl) 2009-07-31

Family

ID=8171588

Family Applications (1)

Application Number Title Priority Date Filing Date
PL360850A PL202576B1 (pl) 2000-06-02 2001-05-30 Zastosowanie szczepu bakterii kwasu mlekowego i zawierająca go kompozycja

Country Status (25)

Country Link
US (2) US20030170184A1 (pl)
EP (2) EP1159951A1 (pl)
JP (1) JP2003534362A (pl)
KR (1) KR20030031490A (pl)
CN (1) CN1279890C (pl)
AR (1) AR028672A1 (pl)
AT (1) ATE343932T1 (pl)
AU (2) AU2001272449B2 (pl)
BR (1) BR0111371A (pl)
CA (1) CA2410591A1 (pl)
DE (1) DE60124255T2 (pl)
ES (1) ES2275697T3 (pl)
HU (1) HUP0301271A2 (pl)
IL (1) IL153127A0 (pl)
IN (1) IN2002CH01972A (pl)
MX (2) MXPA01001038A (pl)
MY (1) MY142363A (pl)
NZ (1) NZ522911A (pl)
PE (1) PE20011328A1 (pl)
PH (1) PH12001001365B1 (pl)
PL (1) PL202576B1 (pl)
PT (1) PT1296636E (pl)
UY (1) UY26748A1 (pl)
WO (1) WO2001091711A1 (pl)
ZA (1) ZA200210308B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1287745A1 (en) 2001-08-24 2003-03-05 The Procter & Gamble Company Chewable compositions with probiotic agents
US8038990B2 (en) * 2005-06-01 2011-10-18 The Ohio State University Compositions and methods for the prevention and removal of biofilms on inert and biological surfaces
CN102245191A (zh) * 2008-12-16 2011-11-16 雀巢产品技术援助有限公司 用于改善口腔健康的组合物和方法
CN103687604A (zh) 2011-03-01 2014-03-26 群体创新有限责任公司 用于治疗与致病生物膜相关之病症的材料和方法
PL3049073T3 (pl) * 2013-09-24 2021-10-25 The Regents Of The University Of Michigan Kompozycje i sposoby destabilizowania, modyfikowania i rozpraszania biofilmów
CN104546941B (zh) * 2014-09-30 2019-01-08 深圳华大基因科技有限公司 内氏放线菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
KR20180016507A (ko) 2015-06-08 2018-02-14 시에이치알. 한센 에이/에스 프로바이오틱 박테리아가 함유된 글리세린-기재 구미 캔디 및 발포 캔디 제품
US11464717B2 (en) 2017-02-10 2022-10-11 Evonik Operations Gmbh Oral care composition containing at least one biosurfactant and fluoride
CN121379862A (zh) * 2025-12-23 2026-01-23 卡士乳业(深圳)有限公司 一种含ct-02菌株的抗感染益生菌剂及其制备方法和应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135739A (en) * 1983-02-15 1992-08-04 Kitasato Kenkyusho Non-cariogenic composition and drink
JPS59220191A (ja) 1983-04-07 1984-12-11 Kitasato Inst:The 非う蝕性組成物および飲料
US4839281A (en) 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
CH671879A5 (pl) 1987-02-26 1989-10-13 Nestle Sa
JPH0421633A (ja) 1990-05-17 1992-01-24 Saikon Medics:Kk 生体下口腔内有用微生物叢の維持管理法および維持管理組成物
FR2672494A1 (fr) 1991-02-13 1992-08-14 Madinier Isabelle Ferments prophylactiques favorisant la prevention de la carie dentaire.
DE4117782C2 (de) 1991-05-28 1997-07-17 Diagnostikforschung Inst Nanokristalline magnetische Eisenoxid-Partikel, Verfahren zu ihrer Herstellung sowie diagnostische und/oder therapeutische Mittel
JPH054927A (ja) 1991-06-28 1993-01-14 Aizo Matsushiro 乳酸菌含有組成物及びその製造方法
EP0768375B2 (fr) 1992-07-06 2002-06-12 Societe Des Produits Nestle S.A. Bactérie lactique
GB9224598D0 (en) 1992-11-24 1993-01-13 Smithkline Beecham Plc Novel compositions
CH684773A5 (fr) 1992-12-28 1994-12-30 Nestle Sa Composition alimentaire anti-cariogène.
CO4560537A1 (es) 1992-12-28 1998-02-10 Nestle Sa Composicion lactea y procedimiento de preparacion
US5368845A (en) 1993-01-07 1994-11-29 Colgate Palmolive Company Oral composition
US5358858A (en) 1994-03-17 1994-10-25 National Science Council Process for preparing phycoerythrin from bangia atropurpurea and porphyra angusta
DK0699689T3 (da) * 1994-08-19 2000-05-08 Nestle Sa Forgrenet polysaccharid, mikroorganisme, der producerer dette, samt præparater indeholdende disse
WO1996007329A1 (en) * 1994-09-09 1996-03-14 University Of Maryland Bacteriophage-encoded enzymes for the treatment and prevention of dental caries and periodontal diseases
JP3101173B2 (ja) 1995-03-22 2000-10-23 雪印乳業株式会社 フローズンヨーグルトの製造法
PT748591E (pt) 1995-06-16 2002-04-29 Nestle Sa Caseinas micelares fluoradas
PT759469E (pt) 1995-08-07 2003-08-29 Nestle Sa Bacteriocina
JP3356599B2 (ja) 1995-09-22 2002-12-16 雪印乳業株式会社 低酸度型フローズンヨーグルトの製造法
KR19990024297A (ko) * 1997-08-07 1999-04-06 오종석 인체 구강내 치태형성을 억제하는 신규한 유산균
CN1240372C (zh) * 1998-08-12 2006-02-08 雀巢制品公司 掺入口腔微生物区系的外源性乳酸菌
DE10034647C1 (de) * 2000-07-14 2002-04-04 3M Espe Ag Verfahren zur Durchführung einer Speichelanalyse

Also Published As

Publication number Publication date
MY142363A (en) 2010-11-30
AU7244901A (en) 2001-12-11
HUP0301271A2 (hu) 2003-08-28
PH12001001365B1 (en) 2009-02-24
ES2275697T3 (es) 2007-06-16
US20030170184A1 (en) 2003-09-11
ATE343932T1 (de) 2006-11-15
US7491386B2 (en) 2009-02-17
WO2001091711A1 (en) 2001-12-06
CN1279890C (zh) 2006-10-18
EP1296636A1 (en) 2003-04-02
EP1159951A1 (en) 2001-12-05
NZ522911A (en) 2003-08-29
DE60124255T2 (de) 2007-06-06
IL153127A0 (en) 2003-06-24
CN1444469A (zh) 2003-09-24
MX243373B (es) 2007-01-19
CA2410591A1 (en) 2001-12-06
MXPA02011973A (es) 2003-04-22
ZA200210308B (en) 2004-03-19
AU2001272449B2 (en) 2005-10-06
JP2003534362A (ja) 2003-11-18
MXPA01001038A (es) 2001-06-01
BR0111371A (pt) 2003-05-20
PT1296636E (pt) 2007-02-28
EP1296636B1 (en) 2006-11-02
UY26748A1 (es) 2001-11-30
DE60124255D1 (de) 2006-12-14
PL202576B1 (pl) 2009-07-31
US20050074416A1 (en) 2005-04-07
KR20030031490A (ko) 2003-04-21
IN2002CH01972A (pl) 2005-02-11
PE20011328A1 (es) 2002-01-23
AR028672A1 (es) 2003-05-21

Similar Documents

Publication Publication Date Title
AR020169A1 (es) Uso de una bacteria lactica para la preparacion de composiciones orales, las composiciones para la salud de la boca que contienen dicha bacteria lactica yel metodo para seleccionar bacterias lacticas de aplicacion en dicho uso
WO2003043517A3 (en) Dentifrice compositions
TW200637587A (en) Anti-caries oral care composition with xylitol
AU580102B2 (en) Oral hygiene composition
WO2002078644A8 (en) Use of ozone for the treatment of dental and oral conditions
GEP20002228B (en) Antibacterial Mouthwash
MXPA03003486A (es) Empleo del aceite de oliva en la elaboracion de un producto para higiene oral para la eliminacion o reduccion de la placa bacteriana y/o bacterias presentes en la cavidad bucal.
BR0318706A (pt) composição herbárea para cuidados oro-dentais e processo para preparar a mesma
WO2006045056A3 (en) Flavonoid composition for treating oral diseases
PT1441688E (pt) Composições sólidas orais antitártaro e antiplaca
MX243373B (es) Uso de una cepa de bacterias lacticas exogenas contra enfermedades relacionadas con actinomyces naeslundii.
AU7032698A (en) Agents for the promotion of oral hygiene and oral health
Premchind et al. Role of biofilm and its effects in orthodontic treatment
DE60206476D1 (de) Remineralisierendes zahnpflegemittel
DE69008350D1 (de) Hygienische zahnzusammensetzung zur verminderung periodontaler krankheiten.
SE0003907D0 (sv) Komposition för eliminering av tandsten ur munnen
DE69519040D1 (de) Zusammensetzung zur hygiene,prophylaxe und behandlung der mundhöhle
EP0519983A4 (en) Use of ketorolac for treatment of periodontal disease
RU2006122208A (ru) Применение остеопонтина в стоматологических композициях
AU2003278199A1 (en) Oral antimicrobial composition and use thereof in the treatment of dental plaque and gingivitis
MY125752A (en) Caries-preventive dentifrice composition
Maiti Denture Sealants in Minimizing Risk of Caries Lesions
TH55264A3 (th) การรวมแลคติกแบคทีเรียจากภายนอกเข้ากับไมโครฟลอราในช่องปาก
Chang et al. CHANCE IN CONCENTRATION OF SALIVARY STREPTOCOCCUS MUTANS FOLLOWING THE APPLICATION OF VARNISH CONTAINING CHLORHEXIDINE IN ORTHODONTIC PATIENTS
Bercy Dental plaque, gingival and periodontal diseases

Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20100530