PL3619300T3 - Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże - Google Patents

Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże

Info

Publication number
PL3619300T3
PL3619300T3 PL18794845.0T PL18794845T PL3619300T3 PL 3619300 T3 PL3619300 T3 PL 3619300T3 PL 18794845 T PL18794845 T PL 18794845T PL 3619300 T3 PL3619300 T3 PL 3619300T3
Authority
PL
Poland
Prior art keywords
genetically modified
yeasts
trehalase
expressing
fermentation processes
Prior art date
Application number
PL18794845.0T
Other languages
English (en)
Inventor
Peter Alan Jauert
Gregory Michael POYNTER
Brian J. Rush
Original Assignee
Cargill, Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cargill, Incorporated filed Critical Cargill, Incorporated
Publication of PL3619300T3 publication Critical patent/PL3619300T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01028—Alpha,alpha-trehalase (3.2.1.28)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/72—Candida
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/87—Saccharomyces lactis ; Kluyveromyces lactis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL18794845.0T 2017-05-04 2018-05-04 Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże PL3619300T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762501288P 2017-05-04 2017-05-04
US201862636716P 2018-02-28 2018-02-28
US201862648679P 2018-03-27 2018-03-27
PCT/US2018/031110 WO2018204798A1 (en) 2017-05-04 2018-05-04 Genetically modified trehalase-expressing yeasts and fermentation processes using such genetically modified yeasts

Publications (1)

Publication Number Publication Date
PL3619300T3 true PL3619300T3 (pl) 2024-04-02

Family

ID=64016775

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18794845.0T PL3619300T3 (pl) 2017-05-04 2018-05-04 Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże

Country Status (9)

Country Link
US (2) US11041218B2 (pl)
EP (1) EP3619300B1 (pl)
CN (1) CN110582567B (pl)
BR (1) BR112019023085A2 (pl)
CA (1) CA3062324A1 (pl)
ES (1) ES2972654T3 (pl)
HU (1) HUE065734T2 (pl)
PL (1) PL3619300T3 (pl)
WO (1) WO2018204798A1 (pl)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3619300T3 (pl) * 2017-05-04 2024-04-02 Cargill, Incorporated Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże
CN111971379B (zh) * 2018-02-28 2025-03-25 嘉吉公司 葡糖淀粉酶工程化酵母和发酵方法
CN112166188B (zh) * 2018-03-27 2024-07-02 嘉吉有限公司 用于使用经工程化的酵母产生乙醇的方法
WO2020057476A1 (zh) * 2018-09-17 2020-03-26 南京百斯杰生物工程有限公司 海藻糖酶在发酵生产中的应用
BR112021009161A2 (pt) * 2018-11-13 2021-08-31 Lallemand Hungary Liquidity Management Llc. Expressão combinada de enzimas de produção de trealose e degradação de trealose
CN109439599B (zh) * 2018-12-25 2020-04-10 江南大学 一株海藻糖酶生产菌及其应用
PY2079066A (es) 2019-11-29 2022-05-26 Danstar Ferment Ag Proceso para desplazar una enzima exógena
CA3163108A1 (en) 2019-11-29 2021-06-03 Lallemand Hungary Liquidity Management Llc Yeast expressing heterologous glucoamylase
CA3161930A1 (en) 2019-12-17 2021-06-24 Eric R. Moellering Recombinant algae having high lipid productivity
US20210348145A1 (en) * 2020-05-11 2021-11-11 Lallemand Hungary Liquidity Management Llc Recombinant yeast host cell expressing an hydrolase
CN114716520B (zh) * 2020-12-22 2022-09-27 中国科学院天津工业生物技术研究所 一种库德里阿兹威毕赤酵母三羧酸转运蛋白及其编码基因与应用
CN114410612B (zh) * 2022-01-21 2025-03-07 中国科学院南海海洋研究所 一种密码子优化的玉足海参海藻糖酶基因及其应用
CA3264118A1 (en) 2022-08-17 2024-02-22 Cargill, Incorporated GENETICALLY MODIFIED YEAST AND FERMENTATION PROCESS FOR ETHANOL PRODUCTION
CN115820714B (zh) * 2022-12-15 2025-03-25 浙江大学杭州国际科创中心 一种提高多聚半乳糖醛酸酶分泌的基因工程菌及其构建方法和应用
CN116814662A (zh) * 2023-08-30 2023-09-29 威海市世代海洋生物科技股份有限公司 一种重组海藻糖酶及其应用
WO2025096364A2 (en) * 2023-10-30 2025-05-08 Cargill, Incorporated Compositions and methods for reducing trehalose during the production of xylitol
WO2025230692A1 (en) * 2024-05-01 2025-11-06 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of xylitol
WO2026049933A1 (en) 2024-08-29 2026-03-05 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of ethanol

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4546082A (en) 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
JPH11243944A (ja) * 1998-03-04 1999-09-14 Natl Food Res Inst 製パン用乾燥耐性実用パン酵母
JP2002505875A (ja) * 1998-03-11 2002-02-26 ノバルティス アクチエンゲゼルシャフト 植物中トレハロース生合成遺伝子の発現
CN1292824C (zh) 2004-04-30 2007-01-03 中国科学院大连化学物理研究所 一种选择吸收降低催化裂化干气中丙烯的方法
WO2015065978A1 (en) 2013-10-28 2015-05-07 Danisco Us Inc. Trehalase in fermentations
CN106687576B (zh) * 2014-03-28 2021-10-29 丹尼斯科美国公司 用于提高乙醇生产的改变的宿主细胞途径
WO2015195934A2 (en) * 2014-06-18 2015-12-23 Cargill, Incorporated Method for fermenting sugars using genetically engineered yeast
EP3253779A1 (en) 2015-02-06 2017-12-13 Cargill, Incorporated Modified glucoamylase enzymes and yeast strains having enhanced bioproduct production
EP3274461A1 (en) 2015-03-27 2018-01-31 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
US10676727B2 (en) * 2015-06-18 2020-06-09 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
CN108474010A (zh) 2015-11-06 2018-08-31 拉勒曼德匈牙利流动性管理有限责任公司 限制发酵中酵母产生的海藻糖
BR112018011902A2 (pt) 2015-12-17 2018-12-04 Cargill Inc método de fermentação, levedura geneticamente modificada, construto de ácido nucleico, vetor, célula hospedeira, meio de fermentação e utilização da levedura geneticamente modificada
WO2018027131A1 (en) 2016-08-05 2018-02-08 Cargill, Incorporated Leader-modified glucoamylase polypeptides and engineered yeast strains having enhanced bioproduct production
CN109906270A (zh) 2016-09-16 2019-06-18 嘉吉公司 经遗传修饰的乳酸消耗酵母以及使用此类经遗传修饰的酵母的发酵工艺
PL3619300T3 (pl) * 2017-05-04 2024-04-02 Cargill, Incorporated Genetycznie zmodyfikowane drożdże wykazujące ekspresję trehalazy i procesy fermentacji wykorzystujące takie genetycznie zmodyfikowane drożdże

Also Published As

Publication number Publication date
CA3062324A1 (en) 2018-11-08
CN110582567A (zh) 2019-12-17
US20210301275A1 (en) 2021-09-30
ES2972654T3 (es) 2024-06-13
CN110582567B (zh) 2024-03-08
US20200063221A1 (en) 2020-02-27
BR112019023085A2 (pt) 2020-06-09
US11802266B2 (en) 2023-10-31
WO2018204798A1 (en) 2018-11-08
HUE065734T2 (hu) 2024-06-28
EP3619300A1 (en) 2020-03-11
US11041218B2 (en) 2021-06-22
EP3619300B1 (en) 2023-11-08
EP3619300A4 (en) 2021-08-18

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