PL363237A1 - Podstawione cukrem 2-azetydynony użyteczne jako środki hipocholesterolemiczne - Google Patents

Podstawione cukrem 2-azetydynony użyteczne jako środki hipocholesterolemiczne

Info

Publication number: PL363237A1
Authority: PL; Poland
Prior art keywords: sugar; substituted; cholesterol; hypocholesterolemic agents; azetidinones useful
Prior art date: 2000-12-20

Application number

PL01363237A

Other languages

English (en)

Other versions

PL208242B1 (pl

Inventor

Anima Ghosal

Shumel Zbaida

Swapan K. Chowdhury

Robert M. Jannucci

Wenqing Feng

Kevin B. Alton

James E. Patrick

Harry R. Davis

Original Assignee

Schering Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-20

Filing date

2001-12-17

Publication date

2004-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22973953&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL363237(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-12-17 Application filed by Schering Corporation filed Critical Schering Corporation

2004-11-15 Publication of PL363237A1 publication Critical patent/PL363237A1/pl

2011-04-29 Publication of PL208242B1 publication Critical patent/PL208242B1/pl

Links

MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 title abstract 3
239000003529 anticholesteremic agent Substances 0.000 title abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 4
235000012000 cholesterol Nutrition 0.000 abstract 2
201000001320 Atherosclerosis Diseases 0.000 abstract 1
229940127226 anticholesterol agent Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL363237A 2000-12-20 2001-12-17 Pochodna 2-azetydynonu, zawierająca ją farmaceutyczna kompozycja i zastosowanie tej pochodnej, oraz farmaceutyczna kompozycja zawierająca kombinację tej pochodnej i zastosowanie takiej kombinacji PL208242B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US25687500P	2000-12-20	2000-12-20
PCT/US2001/049127 WO2002050090A1 (en)	2000-12-20	2001-12-17	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents

Publications (2)

Publication Number	Publication Date
PL363237A1 true PL363237A1 (pl)	2004-11-15
PL208242B1 PL208242B1 (pl)	2011-04-29

Family

ID=22973953

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL363237A PL208242B1 (pl)	2000-12-20	2001-12-17	Pochodna 2-azetydynonu, zawierająca ją farmaceutyczna kompozycja i zastosowanie tej pochodnej, oraz farmaceutyczna kompozycja zawierająca kombinację tej pochodnej i zastosowanie takiej kombinacji

Country Status (34)

Country	Link
US (1)	US20020137690A1 (pl)
EP (1)	EP1347987B1 (pl)
JP (2)	JP4351842B2 (pl)
KR (1)	KR100883461B1 (pl)
CN (1)	CN100475829C (pl)
AR (1)	AR035611A1 (pl)
AT (2)	ATE279425T1 (pl)
AU (2)	AU2002231049B2 (pl)
BR (1)	BR0116212A (pl)
CA (1)	CA2432798C (pl)
CY (1)	CY1106912T1 (pl)
CZ (1)	CZ302193B6 (pl)
DE (2)	DE60106489T2 (pl)
DK (2)	DK1347987T3 (pl)
EC (1)	ECSP034659A (pl)
ES (2)	ES2287826T3 (pl)
GE (1)	GEP20053548B (pl)
HU (1)	HUP0302269A3 (pl)
IL (1)	IL155771A0 (pl)
MA (1)	MA26975A1 (pl)
MX (1)	MXPA03005671A (pl)
MY (1)	MY129148A (pl)
NO (2)	NO326981B1 (pl)
NZ (1)	NZ525722A (pl)
PE (1)	PE20020718A1 (pl)
PL (1)	PL208242B1 (pl)
PT (2)	PT1347987E (pl)
RU (1)	RU2297422C2 (pl)
SI (2)	SI1593670T1 (pl)
SK (1)	SK286703B6 (pl)
TR (1)	TR200402758T4 (pl)
TW (1)	TWI316942B (pl)
WO (1)	WO2002050090A1 (pl)
ZA (1)	ZA200303694B (pl)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
KR20070120617A (ko)	2001-01-26	2007-12-24	쉐링 코포레이션	치환된 아제티딘온 화합물을 포함하는 약제학적 조성물
IL156445A0 (en)	2001-01-26	2004-01-04	Schering Corp	Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
BRPI0208384B1 (pt)	2001-03-28	2016-05-31	Merck Sharp & Dohme	síntese enantiosseletiva de compostos intermediários de azetidinona
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
EP1429756B1 (en)	2001-09-21	2006-11-22	Schering Corporation	Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
AR040588A1 (es) *	2002-07-26	2005-04-13	Schering Corp	Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
CA2504916A1 (en)	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US7459442B2 (en)	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
DE602004018617D1 (de)	2003-03-07	2009-02-05	Schering Corp	Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
WO2004081002A1 (en)	2003-03-07	2004-09-23	Schering Corporation	Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
WO2004081004A1 (en)	2003-03-07	2004-09-23	Schering Corporation	Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
JP2005015434A (ja) *	2003-06-27	2005-01-20	Kotobuki Seiyaku Kk	血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤
EP1522541A1 (en) *	2003-10-07	2005-04-13	Lipideon Biotechnology AG	Novel hypocholesterolemic compounds
EP1918000A2 (en)	2003-11-05	2008-05-07	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
GB0329778D0 (en) *	2003-12-23	2004-01-28	Astrazeneca Ab	Chemical compounds
ATE485267T1 (de)	2003-12-23	2010-11-15	Astrazeneca Ab	Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung
JP2007516287A (ja)	2003-12-23	2007-06-21	メルク　エンド　カムパニー　インコーポレーテッド	抗高コレステロール血症化合物
EP1807070A1 (en) *	2004-09-29	2007-07-18	Schering Corporation	Combinations of substituted azetidinones and cb1 antagonists
US7737155B2 (en)	2005-05-17	2010-06-15	Schering Corporation	Nitrogen-containing heterocyclic compounds and methods of use thereof
AR054482A1 (es) *	2005-06-22	2007-06-27	Astrazeneca Ab	Derivados de azetidinona para el tratamiento de hiperlipidemias
SA06270191B1 (ar) *	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
WO2007103453A1 (en) *	2006-03-06	2007-09-13	Teva Pharmaceutical Industries Ltd.	Ezetimibe compositions
AR060623A1 (es)	2006-04-27	2008-07-02	Astrazeneca Ab	Compuestos derivados de 2-azetidinona y un metodo de preparacion
EP2064222B1 (en) *	2007-04-02	2014-05-07	Theracos, Inc.	Benzylic glycoside derivatives and methods of use
US20110245209A1 (en)	2008-12-16	2011-10-06	Schering Corporation	Pyridopyrimidine derivatives and methods of use thereof
US20110243940A1 (en)	2008-12-16	2011-10-06	Schering Corporation	Bicyclic pyranone derivatives and methods of use thereof
ES2487540T3 (es) *	2009-02-11	2014-08-21	Dow Agrosciences Llc	Composiciones plaguicidas
WO2010100255A1 (en)	2009-03-06	2010-09-10	Lipideon Biotechnology Ag	Pharmaceutical hypocholesterolemic compositions
EP2414529A2 (en)	2009-04-01	2012-02-08	Matrix Laboratories Ltd	Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN101993403B (zh)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	氮杂环丁酮类化合物及医药应用
KR101102749B1 (ko) *	2009-11-30	2012-01-05	최길용	곱셈 학습기
KR20150079373A (ko)	2013-12-30	2015-07-08	한미약품 주식회사	에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제
CN105055404B (zh) *	2015-08-19	2017-07-18	四川大学	Hmgcs2抑制剂在制备治疗可卡因成瘾的药物中的用途

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LT3595B (en) *	1993-01-21	1995-12-27	Schering Corp	Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5627176A (en) *	1994-03-25	1997-05-06	Schering Corporation	Substituted azetidinone compounds useful as hypocholesterolemic agents
US5633246A (en) *	1994-11-18	1997-05-27	Schering Corporation	Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
PT877750E (pt) *	1995-10-31	2002-09-30	Schering Corp	2-azetidinonas substituidas por acucar uteis como agentes hipocolesterolemiantes
US5756470A (en) *	1996-10-29	1998-05-26	Schering Corporation	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
AUPQ342599A0 (en) *	1999-10-14	1999-11-04	University Of Melbourne, The	Conjugates and uses thereof

2001
- 2001-12-17 AT AT01991315T patent/ATE279425T1/de active
- 2001-12-17 AT AT05004699T patent/ATE369334T1/de active
- 2001-12-17 DE DE60106489T patent/DE60106489T2/de not_active Expired - Lifetime
- 2001-12-17 IL IL15577101A patent/IL155771A0/xx not_active IP Right Cessation
- 2001-12-17 PT PT01991315T patent/PT1347987E/pt unknown
- 2001-12-17 ES ES05004699T patent/ES2287826T3/es not_active Expired - Lifetime
- 2001-12-17 TR TR2004/02758T patent/TR200402758T4/xx unknown
- 2001-12-17 CA CA002432798A patent/CA2432798C/en not_active Expired - Fee Related
- 2001-12-17 PT PT05004699T patent/PT1593670E/pt unknown
- 2001-12-17 RU RU2003122520/04A patent/RU2297422C2/ru not_active IP Right Cessation
- 2001-12-17 CN CNB01821133XA patent/CN100475829C/zh not_active Expired - Fee Related
- 2001-12-17 EP EP01991315A patent/EP1347987B1/en not_active Expired - Lifetime
- 2001-12-17 HU HU0302269A patent/HUP0302269A3/hu unknown
- 2001-12-17 DE DE60129863T patent/DE60129863T2/de not_active Expired - Lifetime
- 2001-12-17 AR ARP010105837A patent/AR035611A1/es not_active Application Discontinuation
- 2001-12-17 MX MXPA03005671A patent/MXPA03005671A/es active IP Right Grant
- 2001-12-17 AU AU2002231049A patent/AU2002231049B2/en not_active Ceased
- 2001-12-17 WO PCT/US2001/049127 patent/WO2002050090A1/en not_active Ceased
- 2001-12-17 AU AU3104902A patent/AU3104902A/xx active Pending
- 2001-12-17 BR BR0116212-8A patent/BR0116212A/pt active Search and Examination
- 2001-12-17 SI SI200130760T patent/SI1593670T1/sl unknown
- 2001-12-17 PE PE2001001260A patent/PE20020718A1/es not_active Application Discontinuation
- 2001-12-17 SI SI200130228T patent/SI1347987T1/xx unknown
- 2001-12-17 NZ NZ525722A patent/NZ525722A/en not_active IP Right Cessation
- 2001-12-17 ES ES01991315T patent/ES2230385T3/es not_active Expired - Lifetime
- 2001-12-17 CZ CZ20031674A patent/CZ302193B6/cs not_active IP Right Cessation
- 2001-12-17 US US10/023,295 patent/US20020137690A1/en not_active Abandoned
- 2001-12-17 SK SK770-2003A patent/SK286703B6/sk not_active IP Right Cessation
- 2001-12-17 DK DK01991315T patent/DK1347987T3/da active
- 2001-12-17 PL PL363237A patent/PL208242B1/pl not_active IP Right Cessation
- 2001-12-17 KR KR1020037007778A patent/KR100883461B1/ko not_active Expired - Fee Related
- 2001-12-17 DK DK05004699T patent/DK1593670T3/da active
- 2001-12-17 JP JP2002551983A patent/JP4351842B2/ja not_active Expired - Fee Related
- 2001-12-18 TW TW090131349A patent/TWI316942B/zh not_active IP Right Cessation
- 2001-12-19 MY MYPI20015742A patent/MY129148A/en unknown
2003
- 2003-05-13 ZA ZA200303694A patent/ZA200303694B/en unknown
- 2003-06-19 MA MA27205A patent/MA26975A1/fr unknown
- 2003-06-19 EC EC2003004659A patent/ECSP034659A/es unknown
- 2003-06-19 NO NO20032806A patent/NO326981B1/no not_active IP Right Cessation
2004
- 2004-11-19 GE GEAP8505A patent/GEP20053548B/en unknown
2007
- 2007-10-08 CY CY20071101279T patent/CY1106912T1/el unknown
2008
- 2008-08-29 NO NO20083737A patent/NO20083737L/no not_active Application Discontinuation
2009
- 2009-03-25 JP JP2009075266A patent/JP2009132745A/ja active Pending

Also Published As

Publication number	Publication date
US20020137690A1 (en)	2002-09-26
MY129148A (en)	2007-03-30
NO326981B1 (no)	2009-03-30
PT1593670E (pt)	2007-11-08
PE20020718A1 (es)	2002-08-09
JP2004516299A (ja)	2004-06-03
NO20083737L (no)	2003-08-19
RU2297422C2 (ru)	2007-04-20
WO2002050090A1 (en)	2002-06-27
ES2230385T3 (es)	2005-05-01
CN1483039A (zh)	2004-03-17
HK1056735A1 (en)	2004-02-27
CN100475829C (zh)	2009-04-08
HUP0302269A2 (hu)	2003-10-28
CA2432798A1 (en)	2002-06-27
ES2287826T3 (es)	2007-12-16
DK1347987T3 (da)	2005-01-31
KR100883461B1 (ko)	2009-02-16
CZ302193B6 (cs)	2010-12-08
RU2003122520A (ru)	2005-02-27
IL155771A0 (en)	2003-12-23
ATE369334T1 (de)	2007-08-15
SK286703B6 (sk)	2009-03-05
HUP0302269A3 (en)	2009-08-28
EP1347987B1 (en)	2004-10-13
GEP20053548B (en)	2005-06-27
ZA200303694B (en)	2004-08-13
CA2432798C (en)	2007-02-27
CY1106912T1 (el)	2012-09-26
PT1347987E (pt)	2005-01-31
PL208242B1 (pl)	2011-04-29
HK1084945A1 (en)	2006-08-11
JP4351842B2 (ja)	2009-10-28
SI1347987T1 (en)	2005-02-28
TR200402758T4 (tr)	2004-11-22
MXPA03005671A (es)	2003-10-06
AU2002231049B2 (en)	2006-07-20
DE60106489T2 (de)	2005-10-13
NO20032806D0 (no)	2003-06-19
EP1347987A1 (en)	2003-10-01
JP2009132745A (ja)	2009-06-18
AU3104902A (en)	2002-07-01
MA26975A1 (fr)	2004-12-20
KR20030063414A (ko)	2003-07-28
TWI316942B (en)	2009-11-11
SI1593670T1 (sl)	2007-12-31
NZ525722A (en)	2004-11-26
DE60106489D1 (de)	2004-11-18
ECSP034659A (es)	2003-07-25
BR0116212A (pt)	2003-12-30
WO2002050090A8 (en)	2004-04-15
CZ20031674A3 (cs)	2003-10-15
DK1593670T3 (da)	2007-11-05
DE60129863T2 (de)	2008-04-30
DE60129863D1 (de)	2007-09-20
SK7702003A3 (en)	2003-10-07
NO20032806L (no)	2003-08-19
AR035611A1 (es)	2004-06-16
ATE279425T1 (de)	2004-10-15

Legal Events

Date	Code	Title	Description
2015-02-27	LAPS	Decisions on the lapse of the protection rights	Effective date: 20131217

Publication	Publication Date	Title
MXPA03005671A (es)	2003-10-06	2-azetidinonas sustituidas con azucares utiles como agentes hipocolesterolemicos.
MY114803A (en)	2003-01-31	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
TWI320406B (en)	2010-02-11	Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
WO2001081310A8 (en)	2002-02-07	1-aroyl-piperidinyl benzamidines
MXPA04002167A (es)	2004-06-29	Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
PH12012501351A1 (en)	2014-10-13	Synthesis of eporthilones, intermediates thereto, analogues and uses thereof
YU65802A (sh)	2005-11-28	Derivati azetidina, njihovo dobivanje i farmaceutske smeše koje ih sadrže
BR0208384A (pt)	2004-06-15	Sìntese enantiosseletiva de compostos intermediários de azetidinona
EP1499590B8 (en)	2006-08-02	Piperidine derivatives as potassium channel blockers
MXPA05009503A (es)	2005-10-18	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
TW200509949A (en)	2005-03-16	Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents
TNSN04255A1 (en)	2007-03-12	Ring-substituted diphenyl azetidinones, method for the production thereof, medicaments containing said compounds, and use thereof.
WO2002042271A3 (en)	2002-11-21	Biphenylcarboxamides useful as lipid lowering agents
MXPA02010320A (es)	2004-09-06	Un derivado piridin-1-oxido, y procedimiento para su transformacion en compuestos farmaceuticamente efectivos.
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