PL363237A1 - Podstawione cukrem 2-azetydynony użyteczne jako środki hipocholesterolemiczne - Google Patents

Podstawione cukrem 2-azetydynony użyteczne jako środki hipocholesterolemiczne

Info

Publication number: PL363237A1
Authority: PL; Poland
Prior art keywords: sugar; substituted; cholesterol; hypocholesterolemic agents; azetidinones useful
Prior art date: 2000-12-20

Application number

PL01363237A

Other languages

English (en)

Other versions

PL208242B1 (pl

Inventor

Anima Ghosal

Shumel Zbaida

Swapan K. Chowdhury

Robert M. Jannucci

Wenqing Feng

Kevin B. Alton

James E. Patrick

Harry R. Davis

Original Assignee

Schering Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-20

Filing date

2001-12-17

Publication date

2004-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22973953&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL363237(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-12-17 Application filed by Schering Corporation filed Critical Schering Corporation

2004-11-15 Publication of PL363237A1 publication Critical patent/PL363237A1/pl

2011-04-29 Publication of PL208242B1 publication Critical patent/PL208242B1/pl

Links

MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical class O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 title abstract 3
239000003529 anticholesteremic agent Substances 0.000 title abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 4
235000012000 cholesterol Nutrition 0.000 abstract 2
201000001320 Atherosclerosis Diseases 0.000 abstract 1
229940127226 anticholesterol agent Drugs 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

PL363237A 2000-12-20 2001-12-17 Pochodna 2-azetydynonu, zawierająca ją farmaceutyczna kompozycja i zastosowanie tej pochodnej, oraz farmaceutyczna kompozycja zawierająca kombinację tej pochodnej i zastosowanie takiej kombinacji PL208242B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US25687500P	2000-12-20	2000-12-20
PCT/US2001/049127 WO2002050090A1 (en)	2000-12-20	2001-12-17	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents

Publications (2)

Publication Number	Publication Date
PL363237A1 true PL363237A1 (pl)	2004-11-15
PL208242B1 PL208242B1 (pl)	2011-04-29

Family

ID=22973953

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL363237A PL208242B1 (pl)	2000-12-20	2001-12-17	Pochodna 2-azetydynonu, zawierająca ją farmaceutyczna kompozycja i zastosowanie tej pochodnej, oraz farmaceutyczna kompozycja zawierająca kombinację tej pochodnej i zastosowanie takiej kombinacji

Country Status (34)

Country	Link
US (1)	US20020137690A1 (pl)
EP (1)	EP1347987B1 (pl)
JP (2)	JP4351842B2 (pl)
KR (1)	KR100883461B1 (pl)
CN (1)	CN100475829C (pl)
AR (1)	AR035611A1 (pl)
AT (2)	ATE369334T1 (pl)
AU (2)	AU2002231049B2 (pl)
BR (1)	BR0116212A (pl)
CA (1)	CA2432798C (pl)
CY (1)	CY1106912T1 (pl)
CZ (1)	CZ302193B6 (pl)
DE (2)	DE60129863T2 (pl)
DK (2)	DK1347987T3 (pl)
EC (1)	ECSP034659A (pl)
ES (2)	ES2287826T3 (pl)
GE (1)	GEP20053548B (pl)
HU (1)	HUP0302269A3 (pl)
IL (1)	IL155771A0 (pl)
MA (1)	MA26975A1 (pl)
MX (1)	MXPA03005671A (pl)
MY (1)	MY129148A (pl)
NO (2)	NO326981B1 (pl)
NZ (1)	NZ525722A (pl)
PE (1)	PE20020718A1 (pl)
PL (1)	PL208242B1 (pl)
PT (2)	PT1593670E (pl)
RU (1)	RU2297422C2 (pl)
SI (2)	SI1593670T1 (pl)
SK (1)	SK286703B6 (pl)
TR (1)	TR200402758T4 (pl)
TW (1)	TWI316942B (pl)
WO (1)	WO2002050090A1 (pl)
ZA (1)	ZA200303694B (pl)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
HU230253B1 (hu)	2001-01-26	2015-11-30	Merck Sharp & Dohme Corp	Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DK1355644T3 (da)	2001-01-26	2006-10-23	Schering Corp	Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
DK1373230T3 (da)	2001-03-28	2005-11-07	Schering Corp	Enantiselektiv syntese af azetidinon mellemprodukter
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja)	2001-09-21	2005-02-10	シェーリング　コーポレイション	ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
GB0215579D0 (en) *	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
AR040588A1 (es) *	2002-07-26	2005-04-13	Schering Corp	Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
WO2004043457A1 (en)	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
JP4589919B2 (ja)	2003-03-07	2010-12-01	シェーリングコーポレイション	高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
CA2517571C (en)	2003-03-07	2011-07-05	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja)	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
US7459442B2 (en)	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2005015434A (ja) *	2003-06-27	2005-01-20	Kotobuki Seiyaku Kk	血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤
EP1522541A1 (en) *	2003-10-07	2005-04-13	Lipideon Biotechnology AG	Novel hypocholesterolemic compounds
EP1918000A2 (en)	2003-11-05	2008-05-07	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
AU2004308332B2 (en)	2003-12-23	2008-04-10	Merck Sharp & Dohme Corp.	Anti-hypercholesterolemic compounds
GB0329778D0 (en) *	2003-12-23	2004-01-28	Astrazeneca Ab	Chemical compounds
ATE485267T1 (de)	2003-12-23	2010-11-15	Astrazeneca Ab	Diphenylazetidinonderivate mit die cholesterinabsorption hemmender wirkung
EP1807070A1 (en) *	2004-09-29	2007-07-18	Schering Corporation	Combinations of substituted azetidinones and cb1 antagonists
US7737155B2 (en)	2005-05-17	2010-06-15	Schering Corporation	Nitrogen-containing heterocyclic compounds and methods of use thereof
SA06270191B1 (ar) *	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
AR054482A1 (es) *	2005-06-22	2007-06-27	Astrazeneca Ab	Derivados de azetidinona para el tratamiento de hiperlipidemias
MX2008011418A (es) *	2006-03-06	2008-09-22	Teva Pharma	Composiciones de ezetimibe.
TW200811098A (en)	2006-04-27	2008-03-01	Astrazeneca Ab	Chemical compounds
JP5583003B2 (ja) *	2007-04-02	2014-09-03	セラコス・インコーポレイテッド	ベンジルグルコシド誘導体およびその用途
EP2379547A1 (en)	2008-12-16	2011-10-26	Schering Corporation	Pyridopyrimidine derivatives and methods of use thereof
US20110243940A1 (en)	2008-12-16	2011-10-06	Schering Corporation	Bicyclic pyranone derivatives and methods of use thereof
AU2010213749B2 (en) *	2009-02-11	2015-01-22	Dow Agrosciences Llc	Pesticidal compositions
EP2403848A1 (en)	2009-03-06	2012-01-11	Lipideon Biotechnology AG	Pharmaceutical hypocholesterolemic compositions
WO2010113175A2 (en)	2009-04-01	2010-10-07	Matrix Laboratories Ltd	Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN101993403B (zh)	2009-08-11	2012-07-11	浙江海正药业股份有限公司	氮杂环丁酮类化合物及医药应用
KR101102749B1 (ko) *	2009-11-30	2012-01-05	최길용	곱셈 학습기
KR20150079373A (ko)	2013-12-30	2015-07-08	한미약품 주식회사	에제티미브 및 로수바스타틴을 포함하는 경구용 복합제제
CN105055404B (zh) *	2015-08-19	2017-07-18	四川大学	Hmgcs2抑制剂在制备治疗可卡因成瘾的药物中的用途

Family Cites Families (7)

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Publication number	Priority date	Publication date	Assignee	Title
LT3595B (en) *	1993-01-21	1995-12-27	Schering Corp	Spirocycloalkyl-substituted azetidinones useful as hypocholesterolemic agents
US5631365A (en) *	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5627176A (en) *	1994-03-25	1997-05-06	Schering Corporation	Substituted azetidinone compounds useful as hypocholesterolemic agents
US5633246A (en) *	1994-11-18	1997-05-27	Schering Corporation	Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
EP0877750B1 (en) *	1995-10-31	2002-06-19	Schering Corporation	Sugar-substituted 2-azetidinones useful as hypocholesterolemic a gents
US5756470A (en) *	1996-10-29	1998-05-26	Schering Corporation	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
AUPQ342599A0 (en) *	1999-10-14	1999-11-04	University Of Melbourne, The	Conjugates and uses thereof

2001
- 2001-12-17 ES ES05004699T patent/ES2287826T3/es not_active Expired - Lifetime
- 2001-12-17 JP JP2002551983A patent/JP4351842B2/ja not_active Expired - Fee Related
- 2001-12-17 MX MXPA03005671A patent/MXPA03005671A/es active IP Right Grant
- 2001-12-17 DK DK01991315T patent/DK1347987T3/da active
- 2001-12-17 CA CA002432798A patent/CA2432798C/en not_active Expired - Fee Related
- 2001-12-17 ES ES01991315T patent/ES2230385T3/es not_active Expired - Lifetime
- 2001-12-17 EP EP01991315A patent/EP1347987B1/en not_active Expired - Lifetime
- 2001-12-17 DE DE60129863T patent/DE60129863T2/de not_active Expired - Lifetime
- 2001-12-17 CN CNB01821133XA patent/CN100475829C/zh not_active Expired - Fee Related
- 2001-12-17 PT PT05004699T patent/PT1593670E/pt unknown
- 2001-12-17 KR KR1020037007778A patent/KR100883461B1/ko not_active Expired - Fee Related
- 2001-12-17 WO PCT/US2001/049127 patent/WO2002050090A1/en not_active Ceased
- 2001-12-17 PT PT01991315T patent/PT1347987E/pt unknown
- 2001-12-17 CZ CZ20031674A patent/CZ302193B6/cs not_active IP Right Cessation
- 2001-12-17 PE PE2001001260A patent/PE20020718A1/es not_active Application Discontinuation
- 2001-12-17 DE DE60106489T patent/DE60106489T2/de not_active Expired - Lifetime
- 2001-12-17 SK SK770-2003A patent/SK286703B6/sk not_active IP Right Cessation
- 2001-12-17 HU HU0302269A patent/HUP0302269A3/hu unknown
- 2001-12-17 AU AU2002231049A patent/AU2002231049B2/en not_active Ceased
- 2001-12-17 AR ARP010105837A patent/AR035611A1/es not_active Application Discontinuation
- 2001-12-17 NZ NZ525722A patent/NZ525722A/en not_active IP Right Cessation
- 2001-12-17 PL PL363237A patent/PL208242B1/pl not_active IP Right Cessation
- 2001-12-17 IL IL15577101A patent/IL155771A0/xx not_active IP Right Cessation
- 2001-12-17 SI SI200130760T patent/SI1593670T1/sl unknown
- 2001-12-17 RU RU2003122520/04A patent/RU2297422C2/ru not_active IP Right Cessation
- 2001-12-17 BR BR0116212-8A patent/BR0116212A/pt active Search and Examination
- 2001-12-17 TR TR2004/02758T patent/TR200402758T4/xx unknown
- 2001-12-17 SI SI200130228T patent/SI1347987T1/xx unknown
- 2001-12-17 DK DK05004699T patent/DK1593670T3/da active
- 2001-12-17 AU AU3104902A patent/AU3104902A/xx active Pending
- 2001-12-17 US US10/023,295 patent/US20020137690A1/en not_active Abandoned
- 2001-12-17 AT AT05004699T patent/ATE369334T1/de active
- 2001-12-17 AT AT01991315T patent/ATE279425T1/de active
- 2001-12-18 TW TW090131349A patent/TWI316942B/zh not_active IP Right Cessation
- 2001-12-19 MY MYPI20015742A patent/MY129148A/en unknown
2003
- 2003-05-13 ZA ZA200303694A patent/ZA200303694B/en unknown
- 2003-06-19 MA MA27205A patent/MA26975A1/fr unknown
- 2003-06-19 EC EC2003004659A patent/ECSP034659A/es unknown
- 2003-06-19 NO NO20032806A patent/NO326981B1/no not_active IP Right Cessation
2004
- 2004-11-19 GE GEAP8505A patent/GEP20053548B/en unknown
2007
- 2007-10-08 CY CY20071101279T patent/CY1106912T1/el unknown
2008
- 2008-08-29 NO NO20083737A patent/NO20083737L/no not_active Application Discontinuation
2009
- 2009-03-25 JP JP2009075266A patent/JP2009132745A/ja active Pending

Also Published As

Publication number	Publication date
ZA200303694B (en)	2004-08-13
BR0116212A (pt)	2003-12-30
ATE279425T1 (de)	2004-10-15
SK286703B6 (sk)	2009-03-05
CZ20031674A3 (cs)	2003-10-15
PT1593670E (pt)	2007-11-08
DE60129863T2 (de)	2008-04-30
DE60106489T2 (de)	2005-10-13
CN100475829C (zh)	2009-04-08
ES2287826T3 (es)	2007-12-16
DK1347987T3 (da)	2005-01-31
ATE369334T1 (de)	2007-08-15
NO20032806D0 (no)	2003-06-19
NO20083737L (no)	2003-08-19
RU2003122520A (ru)	2005-02-27
JP2009132745A (ja)	2009-06-18
HK1084945A1 (en)	2006-08-11
JP4351842B2 (ja)	2009-10-28
DE60129863D1 (de)	2007-09-20
WO2002050090A8 (en)	2004-04-15
EP1347987B1 (en)	2004-10-13
KR20030063414A (ko)	2003-07-28
DE60106489D1 (de)	2004-11-18
HUP0302269A3 (en)	2009-08-28
CZ302193B6 (cs)	2010-12-08
DK1593670T3 (da)	2007-11-05
SK7702003A3 (en)	2003-10-07
TWI316942B (en)	2009-11-11
NO20032806L (no)	2003-08-19
PT1347987E (pt)	2005-01-31
MXPA03005671A (es)	2003-10-06
MA26975A1 (fr)	2004-12-20
CA2432798C (en)	2007-02-27
CA2432798A1 (en)	2002-06-27
NZ525722A (en)	2004-11-26
IL155771A0 (en)	2003-12-23
CY1106912T1 (el)	2012-09-26
SI1593670T1 (sl)	2007-12-31
NO326981B1 (no)	2009-03-30
AR035611A1 (es)	2004-06-16
TR200402758T4 (tr)	2004-11-22
PE20020718A1 (es)	2002-08-09
MY129148A (en)	2007-03-30
HUP0302269A2 (hu)	2003-10-28
AU2002231049B2 (en)	2006-07-20
JP2004516299A (ja)	2004-06-03
PL208242B1 (pl)	2011-04-29
AU3104902A (en)	2002-07-01
ECSP034659A (es)	2003-07-25
HK1056735A1 (en)	2004-02-27
SI1347987T1 (en)	2005-02-28
RU2297422C2 (ru)	2007-04-20
WO2002050090A1 (en)	2002-06-27
US20020137690A1 (en)	2002-09-26
CN1483039A (zh)	2004-03-17
KR100883461B1 (ko)	2009-02-16
GEP20053548B (en)	2005-06-27
EP1347987A1 (en)	2003-10-01
ES2230385T3 (es)	2005-05-01

Legal Events

Date	Code	Title	Description
2015-02-27	LAPS	Decisions on the lapse of the protection rights	Effective date: 20131217

Publication	Publication Date	Title
PL363237A1 (pl)	2004-11-15	Podstawione cukrem 2-azetydynony użyteczne jako środki hipocholesterolemiczne
MY114803A (en)	2003-01-31	Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
WO2001081310A8 (en)	2002-02-07	1-aroyl-piperidinyl benzamidines
PL374732A1 (pl)	2005-10-31	Kompozycje farmaceutyczne jako inhibitory peptydazy dipeptydylowej IV (DPP-IV)
MXPA04002167A (es)	2004-06-29	Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
MXPA05009501A (es)	2005-10-18	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
HUP0303876A3 (en)	2005-06-28	Preparation of pharmaceutical compositions for treatment of type 2 diabetes using piperidine or tiazolidine, inhibitors of dipeptidyl peptidase iv
WO2004037181A3 (en)	2004-10-21	Glycinenitrile-based inhibitors of dipeptidyl peptidase iv and methods
WO2003059898A3 (en)	2004-02-26	Eponemycin and epoxomicin analogs and uses thereof
HUP0303526A2 (hu)	2004-01-28	Azetidinon-intermedier vegyületek enantioszelektiv szintézise
YU47803A (sh)	2006-05-25	Derivati difenil-azetidinona, postupak za njihovu proizvodnju, lekovi koji sadrže ova jedinjenja i njihova primena
MXPA05009503A (es)	2005-10-18	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
TW200509949A (en)	2005-03-16	Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions using various agents
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