PL363872A1 - Analogi witaminy D - Google Patents

Analogi witaminy D

Info

Publication number: PL363872A1
Authority: PL; Poland
Prior art keywords: bis; phenyl; trifluoro; carbon atoms; radical
Prior art date: 2001-05-22

Application number

PL02363872A

Other languages

English (en)

Other versions

PL215582B1 (pl

Inventor

Jean-Michel Bernardon

Original Assignee

Galderma Research & Development, S.N.C.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-22

Filing date

2002-05-22

Publication date

2004-11-29

2002-05-22 Application filed by Galderma Research & Development, S.N.C. filed Critical Galderma Research & Development, S.N.C.

2004-11-29 Publication of PL363872A1 publication Critical patent/PL363872A1/pl

2013-12-31 Publication of PL215582B1 publication Critical patent/PL215582B1/pl

Links

229940046008 vitamin d Drugs 0.000 title abstract 2
-1 alkyl radical Chemical class 0.000 abstract 4
125000004432 carbon atom Chemical group C* 0.000 abstract 4
150000005840 aryl radicals Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
GTLCUSKTPJNTRH-YNXPHOCQSA-N (3e,5e)-6-[3-[[3,4-bis(hydroxymethyl)phenyl]methoxy]phenyl]-1,1,1-trifluoro-2-(trifluoromethyl)octa-3,5-dien-2-ol Chemical compound FC(F)(F)C(O)(C(F)(F)F)\C=C\C=C(/CC)C1=CC=CC(OCC=2C=C(CO)C(CO)=CC=2)=C1 GTLCUSKTPJNTRH-YNXPHOCQSA-N 0.000 abstract 1
MQVQVTPMLKHAJK-HFWUGNDSSA-N (4e,6e)-7-[3-[2-[3,4-bis(hydroxymethyl)phenyl]ethyl]phenyl]-3-ethylnona-4,6-dien-3-ol Chemical compound CCC(O)(CC)\C=C\C=C(/CC)C1=CC=CC(CCC=2C=C(CO)C(CO)=CC=2)=C1 MQVQVTPMLKHAJK-HFWUGNDSSA-N 0.000 abstract 1
JRQYVUBDUOPEJR-FBCYGCLPSA-N (e)-6-[3-[2-[3,4-bis(hydroxymethyl)phenyl]ethyl]phenyl]-1,1,1-trifluoro-2-(trifluoromethyl)oct-5-en-3-yn-2-ol Chemical compound FC(F)(F)C(O)(C(F)(F)F)C#C\C=C(/CC)C1=CC=CC(CCC=2C=C(CO)C(CO)=CC=2)=C1 JRQYVUBDUOPEJR-FBCYGCLPSA-N 0.000 abstract 1
LJLDWEAGJAEIGO-UBKPWBPPSA-N (e)-6-[3-[[3,4-bis(hydroxymethyl)phenyl]methoxy]phenyl]-1,1,1-trifluoro-2-(trifluoromethyl)oct-5-en-3-yn-2-ol Chemical compound FC(F)(F)C(O)(C(F)(F)F)C#C\C=C(/CC)C1=CC=CC(OCC=2C=C(CO)C(CO)=CC=2)=C1 LJLDWEAGJAEIGO-UBKPWBPPSA-N 0.000 abstract 1
229930003316 Vitamin D Natural products 0.000 abstract 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
230000024245 cell differentiation Effects 0.000 abstract 1
230000004663 cell proliferation Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
235000019166 vitamin D Nutrition 0.000 abstract 1
239000011710 vitamin D Substances 0.000 abstract 1
150000003710 vitamin D derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/28—Alcohols containing only six-membered aromatic rings as cyclic part with unsaturation outside the aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
- C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
- C07C33/486—Polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Hematology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Oncology (AREA)
Obesity (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Ophthalmology & Optometry (AREA)
Neurosurgery (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

PL363872A 2001-05-22 2002-05-22 Biaromatyczne zwiazki stanowiace analogi witaminy D, kompozycje farmaceutyczne i/lub kosmetyczne zawierajace te zwiazki oraz zastosowania tych zwiazków PL215582B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0106731A FR2825087B1 (fr)	2001-05-22	2001-05-22	Analogues de la vitamine d
PCT/FR2002/001726 WO2002094754A1 (fr)	2001-05-22	2002-05-22	Analogues de la vitamine d

Publications (2)

Publication Number	Publication Date
PL363872A1 true PL363872A1 (pl)	2004-11-29
PL215582B1 PL215582B1 (pl)	2013-12-31

Family

ID=8863543

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL363872A PL215582B1 (pl)	2001-05-22	2002-05-22	Biaromatyczne zwiazki stanowiace analogi witaminy D, kompozycje farmaceutyczne i/lub kosmetyczne zawierajace te zwiazki oraz zastosowania tych zwiazków

Country Status (20)

Country	Link
US (1)	US7700657B2 (pl)
EP (1)	EP1395538B1 (pl)
JP (1)	JP4629309B2 (pl)
KR (1)	KR100878728B1 (pl)
CN (1)	CN1267394C (pl)
AT (1)	ATE453611T1 (pl)
AU (1)	AU2002310684B2 (pl)
BR (1)	BR0205517A (pl)
CA (1)	CA2446149C (pl)
CY (1)	CY1109843T1 (pl)
DE (1)	DE60234920D1 (pl)
DK (1)	DK1395538T3 (pl)
ES (1)	ES2338995T3 (pl)
FR (1)	FR2825087B1 (pl)
MX (1)	MXPA03010628A (pl)
PL (1)	PL215582B1 (pl)
PT (1)	PT1395538E (pl)
RU (1)	RU2266274C2 (pl)
WO (1)	WO2002094754A1 (pl)
ZA (1)	ZA200300668B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1592452B1 (en) *	2003-02-05	2008-10-08	Galderma Research & Development	Invert emulsion type composition containing at least one active agent sensitive to the presence of water, and its uses in cosmetics and in dermatology
US20050124591A1 (en) *	2003-07-29	2005-06-09	Jin Tian	Use of vitamin Ds to treat kidney disease
US20050148557A1 (en) *	2003-07-29	2005-07-07	Jin Tian	Use of Vitamin Ds to treat kidney disease
US20060171983A1 (en) *	2003-07-30	2006-08-03	Jin Tian	Use of Vitamin D receptor activators or Vitamin D analogs to treat cardiovascular disease
US20050192255A1 (en) *	2003-07-30	2005-09-01	Jin Tian	Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease
DE602004012440T2 (de)	2003-11-21	2009-03-26	Galderma Research & Development	Sprühbare zusammensetzung zur verabreichung von vitamin d derivaten
FR2892936A1 (fr) *	2005-11-10	2007-05-11	Galderma Res & Dev	Composition pharmaceutique ou cosmetique, et procede de solubilisation mixte pour preparer la composition.
US8470304B2 (en)	2009-08-04	2013-06-25	Avidas Pharmaceuticals Llc	Therapeutic vitamin D sun-protecting formulations and methods for their use
CN106265695B (zh) *	2009-08-14	2021-05-07	博格有限责任公司	用于治疗脱发的维生素d3及其类似物
JP6942920B2 (ja) *	2015-12-18	2021-09-29	ディーエスエムアイピーアセッツビー．ブイ．ＤｓｍＩｐＡｓｓｅｔｓＢ．Ｖ．	二芳香族ビタミンｄアナログ
EP3389606B1 (en)	2015-12-18	2020-07-15	DSM IP Assets B.V.	Biaromatic vitamin d analogs
US11168054B2 (en)	2015-12-18	2021-11-09	Dsm Ip Assets B.V.	Biaromatic compounds, which are vitamin D analogs
JP6632006B2 (ja) *	2015-12-18	2020-01-15	ディーエスエムアイピーアセッツビー．ブイ．ＤｓｍＩｐＡｓｓｅｔｓＢ．Ｖ．	新規化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2713635B1 (fr) *	1993-12-15	1996-01-05	Cird Galderma	Nouveaux composés propynyl bi-aromatiques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
US5650420A (en)	1994-12-15	1997-07-22	Pharmacia & Upjohn Company	Pramipexole as a neuroprotective agent
FR2741876B1 (fr) *	1995-12-01	1998-01-09	Cird Galderma	Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations
FR2757852B1 (fr)	1996-12-31	1999-02-19	Cird Galderma	Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations
FR2785284B1 (fr) *	1998-11-02	2000-12-01	Galderma Res & Dev	Analogues de la vitamine d
US6659922B1 (en)	2003-04-21	2003-12-09	Jao-Hsing Tsai	Resistance adjustment mechanism for easy pull exerciser

2001
- 2001-05-22 FR FR0106731A patent/FR2825087B1/fr not_active Expired - Fee Related
2002
- 2002-05-22 PL PL363872A patent/PL215582B1/pl unknown
- 2002-05-22 WO PCT/FR2002/001726 patent/WO2002094754A1/fr not_active Ceased
- 2002-05-22 BR BR0205517-1A patent/BR0205517A/pt not_active IP Right Cessation
- 2002-05-22 DE DE60234920T patent/DE60234920D1/de not_active Expired - Lifetime
- 2002-05-22 CN CNB028104579A patent/CN1267394C/zh not_active Expired - Fee Related
- 2002-05-22 KR KR1020037000956A patent/KR100878728B1/ko not_active Expired - Fee Related
- 2002-05-22 PT PT02735556T patent/PT1395538E/pt unknown
- 2002-05-22 MX MXPA03010628A patent/MXPA03010628A/es active IP Right Grant
- 2002-05-22 RU RU2003136744/04A patent/RU2266274C2/ru not_active IP Right Cessation
- 2002-05-22 AT AT02735556T patent/ATE453611T1/de active
- 2002-05-22 CA CA2446149A patent/CA2446149C/fr not_active Expired - Fee Related
- 2002-05-22 ES ES02735556T patent/ES2338995T3/es not_active Expired - Lifetime
- 2002-05-22 JP JP2002591429A patent/JP4629309B2/ja not_active Expired - Fee Related
- 2002-05-22 AU AU2002310684A patent/AU2002310684B2/en not_active Ceased
- 2002-05-22 DK DK02735556.9T patent/DK1395538T3/da active
- 2002-05-22 EP EP02735556A patent/EP1395538B1/fr not_active Expired - Lifetime
2003
- 2003-01-24 ZA ZA200300668A patent/ZA200300668B/en unknown
- 2003-11-24 US US10/718,538 patent/US7700657B2/en not_active Expired - Fee Related
2010
- 2010-02-25 CY CY20101100185T patent/CY1109843T1/el unknown

Also Published As

Publication number	Publication date
AU2002310684B2 (en)	2005-07-21
FR2825087B1 (fr)	2005-01-14
CN1267394C (zh)	2006-08-02
WO2002094754A1 (fr)	2002-11-28
CA2446149C (fr)	2010-07-06
EP1395538A1 (fr)	2004-03-10
JP2004534038A (ja)	2004-11-11
ZA200300668B (en)	2004-06-22
US20040224929A1 (en)	2004-11-11
DK1395538T3 (da)	2010-03-15
JP4629309B2 (ja)	2011-02-09
MXPA03010628A (es)	2004-04-02
PT1395538E (pt)	2010-02-12
KR100878728B1 (ko)	2009-01-14
US7700657B2 (en)	2010-04-20
BR0205517A (pt)	2003-07-01
CN1549803A (zh)	2004-11-24
FR2825087A1 (fr)	2002-11-29
KR20030019601A (ko)	2003-03-06
PL215582B1 (pl)	2013-12-31
CY1109843T1 (el)	2014-09-10
CA2446149A1 (fr)	2002-11-28
DE60234920D1 (de)	2010-02-11
RU2003136744A (ru)	2005-04-10
EP1395538B1 (fr)	2009-12-30
RU2266274C2 (ru)	2005-12-20
ATE453611T1 (de)	2010-01-15
ES2338995T3 (es)	2010-05-14

Legal Events

Date	Code	Title	Description
2015-08-31	RECP	Rectifications of patent specification

Publication	Publication Date	Title
PL363872A1 (pl)	2004-11-29	Analogi witaminy D
IL105481A0 (en)	1993-08-18	Phenyl sulfonamide derivatives and pharmaceutical compositions containing the same
IL114829A (en)	1999-11-30	Biphenyl isoxazole sulfonamide derivatives and pharmaceutical compositions containing the same
AU7194696A (en)	1997-05-29	Bis(resorcinyl)triazines
TW262471B (pl)	1995-11-11
TW224464B (pl)	1994-06-01
YU3902A (sh)	2006-01-16	Imidazoimidazoli i triazoli kao anti-inflamatorna sredstva
SV1993000080A (es)	1996-01-26	Derivados de n4-(oxicarbonil substituidos)-5'-desoxi-5-fluorocitidina ref. ran 4060/166
AU2212392A (en)	1993-03-25	Novel alkoxy substituted taxanes and pharmaceutical compositions containing them
PH12015501098A1 (en)	2015-12-07	Antituberculous composition comprising oxazole compounds
ATE156836T1 (de)	1997-08-15	11,21-bisphenyl-19-nor-pregnan derivate
HU9402615D0 (en)	1994-11-28	Fungicidal mixture
MY133299A (en)	2007-11-30	Skin moisturizing composition comprising a choline salt
WO2000027337A3 (fr)	2000-08-17	Procede de photostabilisation de derives de d,3,5-triazine
WO2000034261A3 (en)	2002-01-31	Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group
AU3083692A (en)	1993-07-19	5,5'-/(1,3-propanediyl) bis-/imino(2-oxo-2,1-ethanediyl)acetylimino/bis(2,4,6-triiod o-1,3-benzenedicarboxyamides), and contrast media containing them
AU2291483A (en)	1984-07-05	Carbamyloxybenzhyrol derivatives
NO994107L (no)	1999-08-25	Preparater for behandling eller forhindring av prostatakreft
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