PL366053A1 - Sposób mierzenia aktywności syntaz NO - Google Patents

Sposób mierzenia aktywności syntaz NO

Info

Publication number
PL366053A1
PL366053A1 PL01366053A PL36605301A PL366053A1 PL 366053 A1 PL366053 A1 PL 366053A1 PL 01366053 A PL01366053 A PL 01366053A PL 36605301 A PL36605301 A PL 36605301A PL 366053 A1 PL366053 A1 PL 366053A1
Authority
PL
Poland
Prior art keywords
synthase
activity
measurement
hts
identification
Prior art date
Application number
PL01366053A
Other languages
English (en)
Other versions
PL204925B1 (pl
Inventor
Hagen-Heinrich Hennies
Bernd Sundermann
Original Assignee
Grunenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grunenthal Gmbh filed Critical Grunenthal Gmbh
Publication of PL366053A1 publication Critical patent/PL366053A1/pl
Publication of PL204925B1 publication Critical patent/PL204925B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90245—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL366053A 2000-09-06 2001-09-04 Sposób mierzenia aktywności syntaz NO, sposób identyfikowania modulatorów syntazy tlenku azotu(II) oraz zastosowanie kationowymiennych membran stanowiących płytki filtracyjne PL204925B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10043845A DE10043845A1 (de) 2000-09-06 2000-09-06 Verfahren zur Messung der Aktivität der NO-Synthase
PCT/EP2001/010151 WO2002020831A2 (de) 2000-09-06 2001-09-04 Verfahren zur messung der aktivität der no-synthase

Publications (2)

Publication Number Publication Date
PL366053A1 true PL366053A1 (pl) 2005-01-24
PL204925B1 PL204925B1 (pl) 2010-02-26

Family

ID=7655147

Family Applications (1)

Application Number Title Priority Date Filing Date
PL366053A PL204925B1 (pl) 2000-09-06 2001-09-04 Sposób mierzenia aktywności syntaz NO, sposób identyfikowania modulatorów syntazy tlenku azotu(II) oraz zastosowanie kationowymiennych membran stanowiących płytki filtracyjne

Country Status (14)

Country Link
US (1) US7045307B2 (pl)
EP (1) EP1315832B1 (pl)
JP (1) JP2004522417A (pl)
AT (1) ATE297472T1 (pl)
AU (2) AU8771101A (pl)
CA (1) CA2417076C (pl)
DE (2) DE10043845A1 (pl)
ES (1) ES2240513T3 (pl)
HU (1) HUP0303657A3 (pl)
MX (1) MXPA03001767A (pl)
NZ (1) NZ525058A (pl)
PL (1) PL204925B1 (pl)
PT (1) PT1315832E (pl)
WO (1) WO2002020831A2 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3138566T (pt) 2003-11-17 2022-02-02 Biomarin Pharm Inc Tratamento de fenilcetonúria com bh4
WO2005052185A1 (en) * 2003-11-26 2005-06-09 Boehringer Ingelheim International Gmbh Detection of no by using guanylyl cyclase and cgmp production as a readout system
US7422845B2 (en) 2003-11-26 2008-09-09 Boehringer Ingelheim International Gmbh Detection of NO by using guanylyl cyclase and cGMP production as a readout system
CN100576687C (zh) * 2003-12-17 2009-12-30 皇家飞利浦电子股份有限公司 应急照明设备
CN101132776A (zh) * 2004-11-17 2008-02-27 生物马林药物股份有限公司 稳定的四氢生物喋呤片剂制剂
US20100278751A1 (en) * 2009-04-30 2010-11-04 Washington University Radiolabeled 2-amino-4-alkyl-6-(haloalkyl)pyridine compounds and their use in diagnostic imaging
GB201101664D0 (en) * 2011-01-31 2011-03-16 Isis Innovation Assay
US9216178B2 (en) 2011-11-02 2015-12-22 Biomarin Pharmaceutical Inc. Dry blend formulation of tetrahydrobiopterin

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574014A (en) * 1976-12-24 1980-09-03 Whatman Reeve Angel Ltd Filter tubes
US4594158A (en) * 1981-09-03 1986-06-10 Rohm And Haas Filter aid materials bearing anion exchange resins
AU559409B2 (en) * 1981-09-22 1987-03-12 Ronald Samson Remotely controlled toy golfer
US5629322A (en) * 1994-11-15 1997-05-13 Merck & Co., Inc. Cyclic amidine analogs as inhibitors of nitric oxide synthase
US5972975A (en) * 1995-12-08 1999-10-26 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
DE19902387A1 (de) * 1999-01-22 2000-07-27 Karl Winkler Verfahren zur in vivo Messung der NO-Synthase Aktivität
HUP0203140A3 (en) * 1999-10-08 2004-06-28 Gruenenthal Gmbh Bicyclic imidazo-5-yl-amine derivatives, process for their preparation and pharmaceutical compositions containing them
KR100756592B1 (ko) * 1999-10-08 2007-09-10 그뤼넨탈 게엠베하 비사이클릭 이미다조-3-일-아민 유도체, 이의 제조방법 및 이를 포함하는 진통제
DE50004817D1 (de) * 1999-10-08 2004-01-29 Gruenenthal Gmbh Am sechsring substituierte, bicyclische imidazo-3-yl-aminderivate
DE19948434A1 (de) * 1999-10-08 2001-06-07 Gruenenthal Gmbh Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine

Also Published As

Publication number Publication date
CA2417076C (en) 2011-07-12
EP1315832A2 (de) 2003-06-04
JP2004522417A (ja) 2004-07-29
HUP0303657A2 (hu) 2004-03-01
NZ525058A (en) 2005-04-29
US7045307B2 (en) 2006-05-16
DE10043845A1 (de) 2002-03-14
MXPA03001767A (es) 2003-06-04
WO2002020831A2 (de) 2002-03-14
ES2240513T3 (es) 2005-10-16
WO2002020831A3 (de) 2002-11-28
HUP0303657A3 (en) 2010-03-29
EP1315832B1 (de) 2005-06-08
AU8771101A (en) 2002-03-22
PL204925B1 (pl) 2010-02-26
CA2417076A1 (en) 2002-03-14
US20040002129A1 (en) 2004-01-01
ATE297472T1 (de) 2005-06-15
PT1315832E (pt) 2005-10-31
AU2001287711B2 (en) 2006-03-30
DE50106468D1 (de) 2005-07-14

Similar Documents

Publication Publication Date Title
AU3487501A (en) Systems, apparatuses and methods for diamond color measurement and analysis
EP0652436A3 (en) Biosensor for measuring alcohol concentration, method for manufacturing the biosensor, and drunkness meter using the biosensor.
EP0985143A4 (en) PHOTOMETER AND TEST SAMPLE HOLDER FOR USE IN SUCH A PHOTOMETER, CORRESPONDING METHOD AND SYSTEM
SG87767A1 (en) Test and burn-in apparatus, in-line system using the apparatus, and test method using the system
BR9807000B1 (pt) transportador de entrada para sistemas de teste de pneu.
AU5994194A (en) Method, test article, and system for performing assays
AU4957699A (en) Fluid sample testing system
DE60037293D1 (de) Fühlerprobe mit Vorrichtung für konstanten Druck
GB0207813D0 (en) Electrochemical detector systems
DE68924615D1 (de) Überwachungssystem für Funkkommunikationsapparate.
DE59203973D1 (de) Zweikomponenten-Druckdose, insbesondere für 2K-Schäume.
BR9404315A (pt) Catalisador, processo para sua preparação e processo para hidroconversão de hidrocarboneto.
DE69836252D1 (de) Tragende Mittel für NMR-Kryostatsystemen
ZA966614B (en) Direct-reading reagent test strip.
AU8771101A (en) Method for measurement of the activity of no-synthase
ZA983792B (en) New cysteine derivatives, processes for their production, and pharmaceuticals containing them.
DE59707122D1 (de) Tragrahmen, insbesondere für zugmittelbetriebene Hebezeuge
BR9917198B1 (pt) dispositivo de teste para detecção ou enumeração de microorganismos, e, processo para utilizar um dispositivo de teste.
GB2379743B (en) A method, a measuring cell and a system for measuring very small heat changes in a sample
AU4943496A (en) Process and compounds for detection of analytes using remanence measurement, and use thereof
DE69803724D1 (de) Fehlerbeseitigungs- und Überwachungsverfahren für eine Analysevorrichtung
ES2153580T3 (es) Complejos quimicos.
FI945850A7 (fi) Puristusnauha tai -hihna, johon kuuluu avoin alustakantaja käytettäväksi pitkän nipin puristimissa ja menetelmä sen valmistamiseksi
DE59511077D1 (de) Analysegerät, insbesondere für Abwasser
AU2001281631A1 (en) Method for carrying out a chemical reaction

Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20130904