PL366372A1 - Sposób i związki pośrednie do wytwarzania latanoprostu - Google Patents

Sposób i związki pośrednie do wytwarzania latanoprostu

Info

Publication number: PL366372A1
Authority: PL; Poland
Prior art keywords: intermediates; contacting; reaction mixture; latanoprost; prepare
Prior art date: 2001-07-17

Application number

PL02366372A

Other languages

English (en)

Inventor

Kevin E. Henegar

Original Assignee

Pharmacia & Upjohn Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-17

Filing date

2002-06-24

Publication date

2005-01-24

2002-06-24 Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company

2005-01-24 Publication of PL366372A1 publication Critical patent/PL366372A1/pl

Links

239000000543 intermediate Substances 0.000 title abstract 3
238000000034 method Methods 0.000 title abstract 2
GGXICVAJURFBLW-CEYXHVGTSA-N latanoprost Chemical compound CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 GGXICVAJURFBLW-CEYXHVGTSA-N 0.000 title 1
229960001160 latanoprost Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
239000011541 reaction mixture Substances 0.000 abstract 2
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
229910052796 boron Inorganic materials 0.000 abstract 1
PSEHHVRCDVOTID-NAVXHOJHSA-N chloro-bis[(1s,3s,4r,5s)-4,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl]borane Chemical compound C([C@@H]([C@H]1C)B(Cl)[C@@H]2[C@@H](C)[C@@]3(C[C@](C2)(C3(C)C)[H])[H])[C@]2([H])C(C)(C)[C@@]1([H])C2 PSEHHVRCDVOTID-NAVXHOJHSA-N 0.000 abstract 1
239000008139 complexing agent Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)

PL02366372A 2001-07-17 2002-06-24 Sposób i związki pośrednie do wytwarzania latanoprostu PL366372A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US30602601P	2001-07-17	2001-07-17
PCT/US2002/020188 WO2003008368A1 (en)	2001-07-17	2002-06-24	Process and intermediates to prepare latanoprost

Publications (1)

Publication Number	Publication Date
PL366372A1 true PL366372A1 (pl)	2005-01-24

Family

ID=23183414

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02366372A PL366372A1 (pl)	2001-07-17	2002-06-24	Sposób i związki pośrednie do wytwarzania latanoprostu

Country Status (15)

Country	Link
US (1)	US6689901B2 (pl)
EP (1)	EP1406854A1 (pl)
JP (2)	JP2004535465A (pl)
KR (2)	KR100581647B1 (pl)
CN (1)	CN1263726C (pl)
AR (1)	AR034797A1 (pl)
BR (1)	BR0211204A (pl)
CA (1)	CA2453631A1 (pl)
IL (1)	IL159632A0 (pl)
MX (1)	MXPA04000473A (pl)
PL (1)	PL366372A1 (pl)
RU (2)	RU2267480C2 (pl)
TW (1)	TWI242551B (pl)
WO (1)	WO2003008368A1 (pl)
ZA (1)	ZA200400163B (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL143477A (en) *	2001-05-31	2009-07-20	Finetech Pharmaceutical Ltd	Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives
IL134241A (en)	2000-01-27	2006-06-11	Finetech Pharmaceutical Ltd	Process for the preparation of latanoprost
KR100437873B1 (ko)	2001-05-08	2004-06-26	연성정밀화학(주)	프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
GB0112699D0 (en) *	2001-05-24	2001-07-18	Resolution Chemicals Ltd	Process for the preparation of prostglandins and analogues thereof
GB0329379D0 (en) *	2003-12-19	2004-01-21	Johnson Matthey Plc	Prostaglandin synthesis
US7109371B2 (en) *	2004-01-05	2006-09-19	Johnson Matthey Public Limited Company	Prostaglandin synthesis
EP2735566A1 (en) *	2006-02-07	2014-05-28	R-Tech Ueno, Ltd.	Method for preparing prostaglandin derivative
JP2008037782A (ja) *	2006-08-04	2008-02-21	Daiichi Fine Chemical Co Ltd	プロスタグランジン誘導体の製造方法
US7642370B2 (en)	2006-08-07	2010-01-05	Daiichi Fine Chemical Co., Ltd.	Method for preparing prostaglandin derivative
CN101555221B (zh) *	2008-04-09	2013-01-23	明德国际仓储贸易(上海)有限公司	一种前列腺素f型衍生物的制造方法
EP2143712A1 (en) *	2008-07-10	2010-01-13	Sandoz AG	Improved Process for the Production of Prostaglandins and Prostaglandin Analogs
IT1392492B1 (it)	2008-12-24	2012-03-09	Ind Chimica Srl	Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.
WO2011095990A2 (en)	2010-02-03	2011-08-11	Fdc Limited	Process for the purification of prostaglandins and analogues thereof
EP2495235B1 (en)	2011-03-04	2015-08-05	Newchem S.p.A.	Process for the synthesis of prostaglandins and intermediates thereof
JP6212485B2 (ja) *	2011-06-02	2017-10-11	キノイン・ゼー・エル・テー	プロスタグランジンアミドの新規製造方法
CA2846264A1 (en) *	2011-08-24	2013-02-28	Apotex Pharmachem Inc.	Dimethyl-(3,3-difluoro-2,2-dihydroxyheptyl)phosphonate and processes for its preparation
JP2012246301A (ja) *	2012-08-10	2012-12-13	Cayman Chemical Co Inc	Ｆ系プロスタグランジン類を調製する方法
EP3091985B1 (en)	2014-01-10	2024-05-08	Manistee Therapeutics, Inc.	Prostanglandins for topical use in the treatment of migraines.
HU231214B1 (hu) *	2014-03-13	2021-11-29	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Új eljárás nagytisztaságú prosztaglandinok előállítására
CN112142703A (zh) *	2020-09-30	2020-12-29	东北制药集团股份有限公司	一种卡前列素氨丁三醇相关杂质左旋丁基15-酮及其制备方法
CN112608294B (zh) *	2020-12-16	2021-10-26	西安国康瑞金制药有限公司	一种拉坦前列腺素的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3904648A (en) *	1973-06-28	1975-09-09	Upjohn Co	Cyclic ortho esters
DE2517773A1 (de) *	1975-04-18	1976-10-28	Schering Ag	Neue 11-oxo-prostaglandin-derivate und verfahren zu ihrer herstellung
FR2344285A1 (fr) *	1976-03-19	1977-10-14	Roussel Uclaf	Nouvelles lactones derivees du cyclopentanol, leur procede de preparation et leur application comme medicaments
US5296504A (en)	1988-09-06	1994-03-22	Kabi Pharmacia	Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
WO1990002553A1 (en)	1988-09-06	1990-03-22	Pharmacia Ab	Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
CA2050820A1 (en) *	1990-09-24	1992-03-25	Pamela M. Simpson	In-situ preparation of diisopinocamphenyl chloroborane
US5545758A (en) *	1994-08-11	1996-08-13	Merck & Co., Inc.	Process for the preparation of diisopinocampheylchloroborane
US5698733A (en) *	1994-09-30	1997-12-16	Alcon Laboratories, Inc.	Use of 9-deoxy prostaglandin derivatives to treat glaucoma
HU223345B1 (hu) *	1995-12-20	2004-08-30	Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt.	Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
US6710051B1 (en)	1997-01-06	2004-03-23	Klaus Trier Aps	Screening method
WO1999016756A1 (en) *	1997-09-29	1999-04-08	Nippon Kayaku Kabushiki Kaisha	Process for the preparation of carbocyclic nucleoside derivatives and intermediates
AU2001261019A1 (en) *	2000-05-15	2001-11-26	Pharmacia And Upjohn Company	Process and intermediates to prepare latanoprost

2002
- 2002-06-24 EP EP02746692A patent/EP1406854A1/en not_active Withdrawn
- 2002-06-24 MX MXPA04000473A patent/MXPA04000473A/es active IP Right Grant
- 2002-06-24 RU RU2004101053/04A patent/RU2267480C2/ru not_active IP Right Cessation
- 2002-06-24 CA CA002453631A patent/CA2453631A1/en not_active Abandoned
- 2002-06-24 KR KR1020047000521A patent/KR100581647B1/ko not_active Expired - Fee Related
- 2002-06-24 PL PL02366372A patent/PL366372A1/pl unknown
- 2002-06-24 BR BR0211204-3A patent/BR0211204A/pt not_active IP Right Cessation
- 2002-06-24 CN CNB028144368A patent/CN1263726C/zh not_active Expired - Fee Related
- 2002-06-24 WO PCT/US2002/020188 patent/WO2003008368A1/en not_active Ceased
- 2002-06-24 JP JP2003513929A patent/JP2004535465A/ja active Pending
- 2002-06-24 IL IL15963202A patent/IL159632A0/xx unknown
- 2002-06-24 KR KR1020057025320A patent/KR100602549B1/ko not_active Expired - Fee Related
- 2002-06-25 US US10/179,499 patent/US6689901B2/en not_active Expired - Fee Related
- 2002-07-09 TW TW091115177A patent/TWI242551B/zh not_active IP Right Cessation
- 2002-07-16 AR ARP020102665A patent/AR034797A1/es unknown
2004
- 2004-01-09 ZA ZA200400163A patent/ZA200400163B/en unknown
2005
- 2005-07-25 RU RU2005123682/04A patent/RU2005123682A/ru not_active Application Discontinuation
2006
- 2006-10-05 JP JP2006274261A patent/JP2007016050A/ja active Pending

Also Published As

Publication number	Publication date
CA2453631A1 (en)	2003-01-30
KR20040018457A (ko)	2004-03-03
KR20060006980A (ko)	2006-01-20
RU2267480C2 (ru)	2006-01-10
CN1263726C (zh)	2006-07-12
US20030045571A1 (en)	2003-03-06
WO2003008368A1 (en)	2003-01-30
KR100581647B1 (ko)	2006-05-22
CN1533372A (zh)	2004-09-29
KR100602549B1 (ko)	2006-07-20
IL159632A0 (en)	2004-06-01
RU2004101053A (ru)	2005-06-27
EP1406854A1 (en)	2004-04-14
ZA200400163B (en)	2005-01-10
JP2004535465A (ja)	2004-11-25
TWI242551B (en)	2005-11-01
HK1065781A1 (en)	2005-03-04
JP2007016050A (ja)	2007-01-25
US6689901B2 (en)	2004-02-10
RU2005123682A (ru)	2007-01-27
BR0211204A (pt)	2004-07-13
AR034797A1 (es)	2004-03-17
MXPA04000473A (es)	2004-12-06

Legal Events

Date	Code	Title	Description
2010-07-30	DISC	Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL366372A1 (pl)	2005-01-24	Sposób i związki pośrednie do wytwarzania latanoprostu
CA2105251A1 (en)	1994-03-02	Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor
MXPA03010721A (es)	2004-07-01	Sintesis de canabinoides.
PL367298A1 (pl)	2005-02-21	Sposób wytwarzania beraprostu i jego soli
HUP0300856A2 (hu)	2003-09-29	Eljárás szubsztituált fenil-acetonitrilek elżállítására
AU2001254998A1 (en)	2001-11-07	Process for the synthesis of a known tetrazol derivative
RU2150472C1 (ru)	2000-06-10	Способ получения диизопинокамфеилхлорборана в реакционной смеси, способ восстановления прохирального кетона
DK1045823T3 (da)	2006-02-13	Proces til fremstilling af visse benzoesyreforbindelser
AU8459401A (en)	2002-03-22	Process for preparing a substituted imidazopyridine compound
IL141394A0 (en)	2002-03-10	Process for the preparation of imidazodiazepine intermediates
JO2433B1 (en)	2008-04-17	Preparation of heterocyclic lindane landscapes
GB0222426D0 (en)	2002-11-06	Chemical process
WO2001083423A3 (en)	2002-02-21	2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof
HUT53586A (en)	1990-11-28	Process for producing glutaric acid derivatives
IL133815A (en)	2005-07-25	Process for the preparation of 2-alkylthiobenzonitrile derivatives
ZA985767B (en)	2000-02-08	Process for thiolating halobenzoic acid intermediates.
HUP9901985A2 (hu)	1999-09-28	Eljárás 3-fenil-1-[(metilén-dioxi)-fenil]-2-indánkarbonsav- és ciklopentapiridin-származékok, és intermedierjeik előállítására, valamint új intermedierjeik
JPS5711938A (en)	1982-01-21	Preparation of 1,1-dialkoxy-3-alkynes
AU2001284755A1 (en)	2002-02-18	Process for the preparation of alkyllithium compounds
NO20034438D0 (no)	2003-10-03	Fremgangsmåte for fremstilling av et 7-kinolyl-3,5- dihydroksyhept-6-enoeat
EP1270556A4 (en)	2005-01-12	VITAMIN D INTERMEDIATES AND METHODS OF MAKING THE SAME
HK1049145A1 (zh)	2003-05-02	4-氰基取代的环己酸的制备方法和中间体
JPS54119452A (en)	1979-09-17	Preparation of dihydrothiophene dioxide derivative