PL366401A1 - Nowe pochodne kwasu winylokarboksylowego i ich zastosowanie jako środków przeciwcukrzycowych, itd. - Google Patents
Nowe pochodne kwasu winylokarboksylowego i ich zastosowanie jako środków przeciwcukrzycowych, itd.Info
- Publication number
- PL366401A1 PL366401A1 PL02366401A PL36640102A PL366401A1 PL 366401 A1 PL366401 A1 PL 366401A1 PL 02366401 A PL02366401 A PL 02366401A PL 36640102 A PL36640102 A PL 36640102A PL 366401 A1 PL366401 A1 PL 366401A1
- Authority
- PL
- Poland
- Prior art keywords
- antidiabetics
- carboxylic acid
- acid derivatives
- vinyl carboxylic
- novel vinyl
- Prior art date
Links
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical class OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 title 1
- 230000003178 anti-diabetic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/42—Singly bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200101154 | 2001-07-30 | ||
| PCT/DK2002/000471 WO2003011807A1 (en) | 2001-07-30 | 2002-07-05 | Novel vinyl carboxylic acid derivatives and their use as antidiabetics etc. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL366401A1 true PL366401A1 (pl) | 2005-01-24 |
Family
ID=8160643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02366401A PL366401A1 (pl) | 2001-07-30 | 2002-07-05 | Nowe pochodne kwasu winylokarboksylowego i ich zastosowanie jako środków przeciwcukrzycowych, itd. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1414778A1 (pl) |
| JP (1) | JP2004536150A (pl) |
| KR (1) | KR20040019087A (pl) |
| CN (1) | CN1537093A (pl) |
| BR (1) | BR0211414A (pl) |
| CA (1) | CA2452665A1 (pl) |
| CZ (1) | CZ2004133A3 (pl) |
| HU (1) | HUP0401575A2 (pl) |
| IL (1) | IL159547A0 (pl) |
| MX (1) | MXPA04000891A (pl) |
| NO (1) | NO20040389L (pl) |
| PL (1) | PL366401A1 (pl) |
| RU (1) | RU2004105956A (pl) |
| WO (1) | WO2003011807A1 (pl) |
| ZA (1) | ZA200400161B (pl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2499380A1 (en) * | 2002-09-05 | 2004-03-18 | Novo Nordisk A/S | Novel vinyl carboxylic acid derivatives and their therapeutical use |
| DE60332860D1 (de) * | 2002-10-28 | 2010-07-15 | High Point Pharmaceuticals Llc | Neue verbindungen, die sich f r die behandlung von durch ppar vermittelten krankheiten eignen |
| KR20050061562A (ko) * | 2002-10-28 | 2005-06-22 | 노보 노르디스크 에이/에스 | 신규 화합물, 그들의 제제 및 사용 |
| US20040242568A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| JP2007511467A (ja) | 2003-05-14 | 2007-05-10 | タケダ サン ディエゴ インコーポレイテッド | ジペプチジルペプチダーゼインヒビター |
| ITRM20030305A1 (it) * | 2003-06-20 | 2004-12-21 | Sigma Tau Ind Farmaceuti | Preparazione di nuovi derivati di acidi fenil o fenossialchil mono e dicarbossilici utili nel trattamento dell'iperglicemia e dell'ipertrigliceridemia tipiche del diabete del tipo ii. |
| MXPA06001601A (es) | 2003-08-13 | 2006-08-25 | Takeda Pharmaceutical | Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa. |
| CA2539403C (en) * | 2003-09-19 | 2013-11-19 | Janssen Pharmaceutica N.V. | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs |
| UA87467C2 (xx) * | 2003-09-19 | 2009-07-27 | Янссен Фармацевтика Н.В | 4-((феноксіалкіл)тіо)феноксіоцтова кислота та її аналоги$4-((феноксиалкил)тио)феноксиуксусная кислота и ее аналоги |
| WO2005105736A1 (en) * | 2004-05-05 | 2005-11-10 | Novo Nordisk A/S | Novel compounds, their preparation and use |
| ES2372617T3 (es) * | 2005-06-30 | 2012-01-24 | High Point Pharmaceuticals, Llc | Ácidos fenoxiacéticos como activadores de ppar-delta. |
| NZ566799A (en) | 2005-09-14 | 2011-04-29 | Takeda Pharmaceutical | Dipeptidyl peptidase inhibitors for treating diabetes |
| JO3006B1 (ar) | 2005-09-14 | 2016-09-05 | Janssen Pharmaceutica Nv | املاح ليسين مبتكرة من مشتقات حامض 4-((فينوكسي الكيل)ثيو) فينوكسي الخليك |
| WO2007035629A2 (en) | 2005-09-16 | 2007-03-29 | Takeda Pharmaceutical Company Limited | Process for the preparation of pyrimidinedione derivatives |
| EA201101085A1 (ru) * | 2005-12-22 | 2012-05-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Феноксиуксусные кислоты в качестве активаторов ppar дельта |
| PE20080188A1 (es) | 2006-04-18 | 2008-03-10 | Janssen Pharmaceutica Nv | Derivados del acido benzoazepin-oxi-acetico como agonistas de ppar-delta usados para aumentar hdl-c, reducir ldl-c y reducir colesterol |
| KR100693132B1 (ko) * | 2006-06-23 | 2007-03-14 | 동해전장 주식회사 | 정션박스내에 삽입된 릴레이의 동작 검사 장치 |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| US20120168303A1 (en) * | 2011-01-05 | 2012-07-05 | Sueng-Nien Kao | Salt water activated emergency lighting device |
| CN103467407B (zh) * | 2013-09-03 | 2015-04-22 | 浙江医药高等专科学校 | 四氮唑羧酸类化合物及其用途 |
| CN103467406B (zh) * | 2013-09-03 | 2014-12-17 | 浙江医药高等专科学校 | 卤素取代的四氮唑羧酸类化合物、其制备方法和用途 |
| CN103467408B (zh) * | 2013-09-03 | 2015-01-21 | 浙江医药高等专科学校 | 一类四氮唑羧酸类化合物及其用途 |
| CN103467409B (zh) * | 2013-09-03 | 2015-01-07 | 浙江医药高等专科学校 | 取代的四氮唑羧酸类化合物及其用途 |
| CN103467405B (zh) * | 2013-09-03 | 2015-01-07 | 浙江医药高等专科学校 | 一类四氮唑羧酸类化合物、其制备方法和用途 |
| CA3185909A1 (en) | 2020-07-22 | 2022-01-27 | Reneo Pharmaceuticals, Inc. | Crystalline ppar-delta agonist |
| WO2023147309A1 (en) | 2022-01-25 | 2023-08-03 | Reneo Pharmaceuticals, Inc. | Use of ppar-delta agonists in the treatment of disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3373467D1 (en) * | 1982-06-14 | 1987-10-15 | Takeda Chemical Industries Ltd | Vinyl carboxylic acid derivatives, their production and use |
| WO1997043241A1 (en) * | 1996-05-13 | 1997-11-20 | Nippon Shinyaku Co., Ltd. | Substituted ethylene compounds and drugs |
| HUP0200807A3 (en) * | 1999-04-20 | 2003-03-28 | Novo Nordisk As | Substituted propionic acid derivatives, process for their preparation, pharmaceutical compositions containing them and their use |
| KR20020070508A (ko) * | 2000-01-28 | 2002-09-09 | 노보 노르디스크 에이/에스 | 프로피온산 유도체 및 당뇨병 및 비만의 치료에 그것의 사용 |
-
2002
- 2002-07-05 EP EP02745186A patent/EP1414778A1/en not_active Withdrawn
- 2002-07-05 CA CA002452665A patent/CA2452665A1/en not_active Abandoned
- 2002-07-05 PL PL02366401A patent/PL366401A1/pl not_active Application Discontinuation
- 2002-07-05 KR KR10-2004-7001417A patent/KR20040019087A/ko not_active Withdrawn
- 2002-07-05 HU HU0401575A patent/HUP0401575A2/hu unknown
- 2002-07-05 JP JP2003517001A patent/JP2004536150A/ja active Pending
- 2002-07-05 RU RU2004105956/04A patent/RU2004105956A/ru not_active Application Discontinuation
- 2002-07-05 MX MXPA04000891A patent/MXPA04000891A/es unknown
- 2002-07-05 CN CNA028150996A patent/CN1537093A/zh active Pending
- 2002-07-05 CZ CZ2004133A patent/CZ2004133A3/cs unknown
- 2002-07-05 BR BR0211414-3A patent/BR0211414A/pt not_active IP Right Cessation
- 2002-07-05 WO PCT/DK2002/000471 patent/WO2003011807A1/en not_active Ceased
- 2002-07-05 IL IL15954702A patent/IL159547A0/xx unknown
-
2004
- 2004-01-09 ZA ZA200400161A patent/ZA200400161B/en unknown
- 2004-01-29 NO NO20040389A patent/NO20040389L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040019087A (ko) | 2004-03-04 |
| CN1537093A (zh) | 2004-10-13 |
| IL159547A0 (en) | 2004-06-01 |
| ZA200400161B (en) | 2004-08-18 |
| MXPA04000891A (es) | 2004-05-21 |
| HUP0401575A2 (hu) | 2004-11-29 |
| EP1414778A1 (en) | 2004-05-06 |
| CZ2004133A3 (cs) | 2004-06-16 |
| BR0211414A (pt) | 2004-08-17 |
| CA2452665A1 (en) | 2003-02-13 |
| NO20040389L (no) | 2004-01-29 |
| JP2004536150A (ja) | 2004-12-02 |
| WO2003011807A1 (en) | 2003-02-13 |
| RU2004105956A (ru) | 2005-03-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL159547A0 (en) | Novel vinyl carboxylic acid derivatives and their use as antidiabetics | |
| MXPA03009565A (es) | Derivado de acido carboxilico y una sal del mismo. | |
| IL160707A0 (en) | 1, 8-naphthyridine derivatives as antidiabetics | |
| AU2001287898A1 (en) | Pyrazolopyridines and pyrazolopyridazines as antidiabetics | |
| ZA200210411B (en) | Novel heteroaryl derivatives and the use thereof as pharmaceuticals. | |
| ZA200210180B (en) | Novel heteroaryl derivatives and the use thereof as pharmaceuticals. | |
| ZA200406362B (en) | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives and their use as antibacterials. | |
| ZA200200695B (en) | Mutilin derivatives and their use as antibacterials. | |
| ZA200410054B (en) | Propionic acid derivatives and their use as hPPARsactivators. | |
| AU2001289675A1 (en) | Novel Heteroaryl Derivatives and the Use Thereof as Pharmaceuticals | |
| AU2001279757A1 (en) | Novel heteroaryl derivatives and the use thereof as pharmaceuticals | |
| PL375700A1 (pl) | Nowe pochodne kwasu winylokarboksylowego i ich zastosowanie terapeutyczne | |
| AU2001275677A1 (en) | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | |
| AU2001267583A1 (en) | Biphenylcarboxylic acid amides, production thereof and use thereof as medicaments | |
| IL166821A0 (en) | Novel 1,4-diazabicycloalkane derivatives their preparation and use | |
| AU2001235437A1 (en) | Isothiazolecarboxylic acid derivatives and their use as microbicides | |
| MXPA03008186A (es) | Amidas de acidos carboxilicos antitromboticas, su preparacion y su uso como medicamentos. | |
| HUP0300222A3 (en) | Novel lhrh-antagonists, production and use thereof as medicament | |
| AU2002212176A1 (en) | Substituted phenylcyclohexane carboxylic acid amides and the use thereof | |
| AU2001291235A1 (en) | 22108 and 47916, novel human thioredoxin family members and uses thereof | |
| MXPA03006580A (es) | Amidas de acido carboxilico, su produccion y su uso como medicamentos. | |
| AU2001252254A1 (en) | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparationthereof and use thereof | |
| AP2004003005A0 (en) | Novel alpha-oxygenated or alpha-thiolated carboxylic acid penethylamide derivatives. | |
| AU2002331114A1 (en) | Tetrahydroisochinolines, their production and the use thereof as analgesics | |
| PL372089A1 (pl) | Podstawione pochodne propano-1,3-diaminy i ich farmaceutyczne zastosowanie |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |