PL367128A1 - Nowe związki i kompozycje jako inhibitory katepsyny - Google Patents

Nowe związki i kompozycje jako inhibitory katepsyny

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Publication number
PL367128A1
PL367128A1 PL02367128A PL36712802A PL367128A1 PL 367128 A1 PL367128 A1 PL 367128A1 PL 02367128 A PL02367128 A PL 02367128A PL 36712802 A PL36712802 A PL 36712802A PL 367128 A1 PL367128 A1 PL 367128A1
Authority
PL
Poland
Prior art keywords
cathepsin
inhibitors
pharmaceutical compositions
chemical compounds
compounds
Prior art date
Application number
PL02367128A
Other languages
English (en)
Inventor
Michael Graupe
Jiayao Li
John O. Link
Sheila Zipfel
Andreas P. Timm
David J. Aldous
Sukanthini Thurairatnam
Original Assignee
Axys Pharmaceuticals, Inc.
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axys Pharmaceuticals, Inc., Aventis Pharmaceuticals Inc. filed Critical Axys Pharmaceuticals, Inc.
Publication of PL367128A1 publication Critical patent/PL367128A1/pl

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered

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PL02367128A 2001-06-01 2002-06-03 Nowe związki i kompozycje jako inhibitory katepsyny PL367128A1 (pl)

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BRPI0410979A (pt) 2003-09-18 2006-07-04 Axys Pharm Inc composto, composição farmacêutica, e, métodos para tratar uma doença em um animal mediada pela catepsina s e para tratar um paciente submetido a uma terapia
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WO2002098850A3 (en) 2003-04-24
US20040142999A1 (en) 2004-07-22
ZA200308392B (en) 2005-01-28
KR20040015725A (ko) 2004-02-19
EP1397340A2 (en) 2004-03-17
AU2002305790B2 (en) 2008-01-31
CA2448418A1 (en) 2002-12-12
NZ528944A (en) 2007-09-28
EA200301203A1 (ru) 2004-04-29
EA007335B1 (ru) 2006-08-25
IL159125A0 (en) 2004-05-12
HRP20030995A2 (en) 2005-08-31
NO20035328D0 (no) 2003-11-28
JP2004535422A (ja) 2004-11-25
WO2002098850A2 (en) 2002-12-12
RS94603A (sr) 2007-02-05
CN1512983A (zh) 2004-07-14
MXPA03010766A (es) 2005-03-07
BR0210912A (pt) 2004-08-31

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