PL367221A1 - Sposób wytwarzania stałych preparatów 3-hydroksy-3-metylomaślanu sodu - Google Patents

Sposób wytwarzania stałych preparatów 3-hydroksy-3-metylomaślanu sodu

Info

Publication number: PL367221A1
Authority: PL; Poland
Prior art keywords: methylbutyrate; hydroxy; sodium; solid formulations; production
Prior art date: 2001-05-18

Application number

PL02367221A

Other languages

English (en)

Inventor

Brigitta Heyl-Frank

Heike Irle

Daniel Pianzola

Uwe Zacher

Barry Jackson

Original Assignee

Lonza Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-18

Filing date

2002-05-17

Publication date

2005-02-21

2002-05-17 Application filed by Lonza Ag filed Critical Lonza Ag

2005-02-21 Publication of PL367221A1 publication Critical patent/PL367221A1/pl

Links

238000000034 method Methods 0.000 title abstract 3
CPRWZXWNQXUOOJ-UHFFFAOYSA-M sodium;3-hydroxy-3-methylbutanoate Chemical compound [Na+].CC(C)(O)CC([O-])=O CPRWZXWNQXUOOJ-UHFFFAOYSA-M 0.000 title abstract 3
238000009472 formulation Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
239000007787 solid Substances 0.000 title abstract 2
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
WHBGXDGQNOAWLX-UHFFFAOYSA-N 4,4-dimethyloxetan-2-one Chemical compound CC1(C)CC(=O)O1 WHBGXDGQNOAWLX-UHFFFAOYSA-N 0.000 abstract 1
239000000377 silicon dioxide Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Obesity (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Fats And Perfumes (AREA)
Fodder In General (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicinal Preparation (AREA)

PL02367221A 2001-05-18 2002-05-17 Sposób wytwarzania stałych preparatów 3-hydroksy-3-metylomaślanu sodu PL367221A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01112236		2001-05-18

Publications (1)

Publication Number	Publication Date
PL367221A1 true PL367221A1 (pl)	2005-02-21

Family

ID=8177477

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02367221A PL367221A1 (pl)	2001-05-18	2002-05-17	Sposób wytwarzania stałych preparatów 3-hydroksy-3-metylomaślanu sodu

Country Status (16)

Country	Link
US (1)	US7026507B2 (pl)
EP (1)	EP1399138B1 (pl)
JP (1)	JP4166580B2 (pl)
CN (1)	CN100542525C (pl)
AT (1)	ATE317259T1 (pl)
AU (1)	AU2002338953B2 (pl)
BR (1)	BR0209820A (pl)
CA (1)	CA2447417C (pl)
CZ (1)	CZ302823B6 (pl)
DE (1)	DE50205794D1 (pl)
DK (1)	DK1399138T3 (pl)
ES (1)	ES2257559T3 (pl)
HU (1)	HUP0400080A3 (pl)
MX (1)	MXPA03010610A (pl)
PL (1)	PL367221A1 (pl)
WO (1)	WO2002094255A1 (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0402118D0 (en)	2004-01-30	2004-03-03	Merck Sharp & Dohme	Polymorphic forms of a GABAA agonist
EP1848420A4 (en)	2005-01-28	2008-01-23	Merck & Co Inc	POLYMORPH SHAPES OF A GABAA AGONIST
MX2010011963A (es) *	2008-05-02	2010-12-06	Gilead Sciences Inc	Uso de particulas trasportadoras solidas para mejorar la capacidad de procesamiento de un agente farmaceutico.
EP2295593A1 (en)	2009-09-15	2011-03-16	Philippe Marliere	Method for the enymatic production of 3-hydroxy-3-methylbutyric acid from acetone and acetyl-CoA
WO2012140276A2 (en) *	2011-11-17	2012-10-18	Lonza Ltd	Process for the preparation of 3-hydroxy-3-methylbutyric acid or its calcium salts
CN108473411B (zh)	2015-11-19	2022-08-12	协和发酵生化株式会社	3-羟基异戊酸的一价阳离子盐的晶体及该晶体的制造方法
CA3028608A1 (en)	2016-06-24	2017-12-28	Otsuka Pharmaceutical Factory, Inc.	Crystal of amino acid salt of 3-hydroxyisovaleric acid and production method thereof
WO2019016883A1 (ja) *	2017-07-19	2019-01-24	小林香料株式会社	３－ヒドロキシ－３－メチルブタン酸又はその塩の製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2142353T3 (es)	1992-09-16	2000-04-16	Univ Iowa State Res Found Inc	Procedimiento para reducir los niveles de colesterol total y de colesterol asociado a lipoproteinas de baja densidad en sangre.
US5348979A (en)	1992-12-23	1994-09-20	Iowa State University Research Foundation Inc.	Method of promoting nitrogen retention in humans
US6090978A (en) *	1996-07-19	2000-07-18	Met-Rx Usa, Inc.	Process for manufacturing 3-hydroxy-3-methylbutanoic acid
AU6495298A (en) *	1997-02-10	1998-08-26	Lonza A.G.	Process for preparing 3-hydroxy-3-methylbutyric acid or its salts
WO2000014080A1 (en) *	1998-09-03	2000-03-16	Firmenich S.A.	Geranic acid derivatives

2002
- 2002-05-17 BR BR0209820-2A patent/BR0209820A/pt not_active IP Right Cessation
- 2002-05-17 DE DE50205794T patent/DE50205794D1/de not_active Expired - Lifetime
- 2002-05-17 CA CA2447417A patent/CA2447417C/en not_active Expired - Fee Related
- 2002-05-17 EP EP02743039A patent/EP1399138B1/de not_active Expired - Lifetime
- 2002-05-17 CN CNB028135997A patent/CN100542525C/zh not_active Expired - Fee Related
- 2002-05-17 DK DK02743039T patent/DK1399138T3/da active
- 2002-05-17 AT AT02743039T patent/ATE317259T1/de active
- 2002-05-17 AU AU2002338953A patent/AU2002338953B2/en not_active Ceased
- 2002-05-17 MX MXPA03010610A patent/MXPA03010610A/es active IP Right Grant
- 2002-05-17 HU HU0400080A patent/HUP0400080A3/hu unknown
- 2002-05-17 WO PCT/EP2002/005435 patent/WO2002094255A1/de not_active Ceased
- 2002-05-17 CZ CZ20032965A patent/CZ302823B6/cs not_active IP Right Cessation
- 2002-05-17 US US10/478,054 patent/US7026507B2/en not_active Expired - Fee Related
- 2002-05-17 PL PL02367221A patent/PL367221A1/pl not_active Application Discontinuation
- 2002-05-17 JP JP2002590973A patent/JP4166580B2/ja not_active Expired - Fee Related
- 2002-05-17 ES ES02743039T patent/ES2257559T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CZ20032965A3 (cs)	2004-02-18
AU2002338953C1 (en)	2002-12-03
JP2004536065A (ja)	2004-12-02
WO2002094255A1 (de)	2002-11-28
CA2447417C (en)	2011-10-04
AU2002338953B2 (en)	2006-06-29
CN100542525C (zh)	2009-09-23
ATE317259T1 (de)	2006-02-15
DE50205794D1 (de)	2006-04-20
EP1399138A1 (de)	2004-03-24
ES2257559T3 (es)	2006-08-01
BR0209820A (pt)	2004-06-01
HUP0400080A3 (en)	2004-10-28
HUP0400080A2 (hu)	2004-05-28
HK1068813A1 (en)	2005-05-06
MXPA03010610A (es)	2004-04-02
US7026507B2 (en)	2006-04-11
CA2447417A1 (en)	2002-11-28
EP1399138B1 (de)	2006-02-08
JP4166580B2 (ja)	2008-10-15
US20040143136A1 (en)	2004-07-22
CN1523983A (zh)	2004-08-25
CZ302823B6 (cs)	2011-11-30
DK1399138T3 (da)	2006-04-24

Similar Documents

Publication	Publication Date	Title
BR0013885A (pt)	2002-05-07	Comprimidos aperfeiçoados
PL367221A1 (pl)	2005-02-21	Sposób wytwarzania stałych preparatów 3-hydroksy-3-metylomaślanu sodu
AU2001290245A1 (en)	2002-04-08	Aqueous solution of aminated silanol compound, use thereof, and process for producing the same
WO2002030870A3 (de)	2003-10-02	Substituierte c-cyclohexylmethylamin-derivate
CA2412049A1 (en)	2001-12-20	Process for the preparation of 5-aminosalicyclic acid
IL158998A0 (en)	2004-05-12	Process for the production of 4-amino-2, 5-bisheterocyclylquinazolines
AU2001223714A1 (en)	2001-07-24	Method for producing n-methyl-n'-nitroguanidine
WO2001049651A3 (de)	2002-05-23	Aminomethyl-phenyl-cyclohexanonderivate
AU2002219127A1 (en)	2002-06-03	Process for the production of ceftifur sodium salt
ATE259772T1 (de)	2004-03-15	Verfahren zum herstellen von trimethylhydroquinondiacetat und trimethylhydroquinon
CA2402364A1 (en)	2001-09-27	Process for producing camptothecin
ATE446952T1 (de)	2009-11-15	Herstellungsverfahren von 2-cyanopyridinen
PL353291A1 (en)	2002-10-21	Novel compounds, method of obtaining them, their application as pigments and composition containing them
AU4291901A (en)	2001-09-24	Process for the production of 2-hydroxyethylmaleimide and the product obtained by the process
MY120868A (en)	2005-11-30	Novel process.
BG108151A (en)	2004-09-30	Caloporoside derivatives, methods for the production thereof and their use
EP1300391A4 (en)	2006-01-04	PROCESS FOR PREPARING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES
MXPA03003466A (es)	2004-09-10	Derivados de piranosido.
MY127737A (en)	2006-12-29	Novel process for the preparation of pyrazolopyrimidinones
AU2002358317A1 (en)	2003-07-30	Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives
IL145017A0 (en)	2002-06-30	METHOD FOR PRODUCING 4,4-DIMETHYL-3β-HYDROXYPREGNA-8,14-DIENE-21 -CARBOXYLIC ACID ESTERS AND INTERMEDIATE PRODUCTS OBTAINED BY SAID METHOD
CA2364862A1 (en)	2000-09-08	Process for preparing derivatives of biphenyl-2-carboxylic acid
FR2791682B1 (fr)	2001-06-22	Procede de preparation du 4'-demethyl-4'-phosphate-2", 3"-bis pentafluorophenoxyacetyl-4",6"-ethyldidene-beta-d- glucoside d'epipodophyllotoxine, et de ses sels
TW346487B (en)	1998-12-01	Preparation of (S)-aminopropandiol derivatives
RU98112901A (ru)	2000-03-27	СПОСОБ ПОЛУЧЕНИЯ α-ИЗОМЕРА 2,5-ДИМЕТИЛПИПЕРИДО 4-ГИДРОКСИПИПЕРИДИНА-ПОЛУПРОДУКТА В ПРОИЗВОДСТВЕ МЕСТНООБЕЗБОЛИВАЮЩЕГО ПРЕПАРАТА РИХЛОКАИН

Legal Events

Date	Code	Title	Description
2014-05-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)