PL368228A1 - Pochodne kwasu hydroksamowego - Google Patents

Pochodne kwasu hydroksamowego

Info

Publication number: PL368228A1
Authority: PL; Poland
Prior art keywords: sub; sup; compounds; acid derivatives; hydroxamic acid
Prior art date: 2001-08-09

Application number

PL02368228A

Other languages

English (en)

Inventor

Hazel Joan Dyke

Robert John Watson

Original Assignee

Celltech R & D Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-09

Filing date

2002-08-07

Publication date

2005-03-21

2002-08-07 Application filed by Celltech R & D Limited filed Critical Celltech R & D Limited

2005-03-21 Publication of PL368228A1 publication Critical patent/PL368228A1/pl

Links

NEAQRZUHTPSBBM-UHFFFAOYSA-N 2-hydroxy-3,3-dimethyl-7-nitro-4h-isoquinolin-1-one Chemical compound C1=C([N+]([O-])=O)C=C2C(=O)N(O)C(C)(C)CC2=C1 NEAQRZUHTPSBBM-UHFFFAOYSA-N 0.000 title 1
239000002253 acid Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
208000006820 Arthralgia Diseases 0.000 abstract 1
229940124761 MMP inhibitor Drugs 0.000 abstract 1
208000000491 Tendinopathy Diseases 0.000 abstract 1
206010043255 Tendonitis Diseases 0.000 abstract 1
238000010171 animal model Methods 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
201000004415 tendinitis Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Immunology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

PL02368228A 2001-08-09 2002-08-07 Pochodne kwasu hydroksamowego PL368228A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0119396.0A GB0119396D0 (en)	2001-08-09	2001-08-09	Hydroxamic acid derivatives
PCT/GB2002/003656 WO2003014101A1 (en)	2001-08-09	2002-08-07	Hydroxamic acid derivatives

Publications (1)

Publication Number	Publication Date
PL368228A1 true PL368228A1 (pl)	2005-03-21

Family

ID=9920067

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02368228A PL368228A1 (pl)	2001-08-09	2002-08-07	Pochodne kwasu hydroksamowego

Country Status (21)

Country	Link
US (1)	US7015234B2 (pl)
EP (1)	EP1414812B1 (pl)
JP (1)	JP2005501090A (pl)
KR (1)	KR20040035725A (pl)
CN (1)	CN1275954C (pl)
AT (1)	ATE318263T1 (pl)
BR (1)	BR0211780A (pl)
CA (1)	CA2456291A1 (pl)
DE (1)	DE60209354T2 (pl)
EA (1)	EA006877B1 (pl)
ES (1)	ES2257561T3 (pl)
GB (1)	GB0119396D0 (pl)
HU (1)	HUP0401187A2 (pl)
IL (1)	IL160266A0 (pl)
MX (1)	MXPA04001212A (pl)
NO (1)	NO20040551L (pl)
NZ (1)	NZ531521A (pl)
PL (1)	PL368228A1 (pl)
PT (1)	PT1414812E (pl)
WO (1)	WO2003014101A1 (pl)
ZA (1)	ZA200401873B (pl)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4166452A (en)	1976-05-03	1979-09-04	Generales Constantine D J Jr	Apparatus for testing human responses to stimuli
US4256108A (en)	1977-04-07	1981-03-17	Alza Corporation	Microporous-semipermeable laminated osmotic system
US4265874A (en)	1980-04-25	1981-05-05	Alza Corporation	Method of delivering drug with aid of effervescent activity generated in environment of use
US6187924B1 (en) *	1997-11-12	2001-02-13	Darwin Discovery, Ltd.	Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity
WO1999024399A1 (en) *	1997-11-12	1999-05-20	Darwin Discovery Limited	Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
GEP20043238B (en) *	1999-02-08	2004-05-25	Searle & Co	Sulfamato Hydroxamic Acid Metalloprotease Inhibitor, its Use in Preparation of Pharmaceutical Composition for Treatment of Conditions Associated with Pathological Matrix Metalloprotease Activity

2001
- 2001-08-09 GB GBGB0119396.0A patent/GB0119396D0/en not_active Ceased
2002
- 2002-08-07 NZ NZ531521A patent/NZ531521A/en unknown
- 2002-08-07 MX MXPA04001212A patent/MXPA04001212A/es unknown
- 2002-08-07 EA EA200400287A patent/EA006877B1/ru unknown
- 2002-08-07 ES ES02747621T patent/ES2257561T3/es not_active Expired - Lifetime
- 2002-08-07 PT PT02747621T patent/PT1414812E/pt unknown
- 2002-08-07 JP JP2003519051A patent/JP2005501090A/ja active Pending
- 2002-08-07 CN CNB028200225A patent/CN1275954C/zh not_active Expired - Fee Related
- 2002-08-07 AT AT02747621T patent/ATE318263T1/de not_active IP Right Cessation
- 2002-08-07 US US10/485,905 patent/US7015234B2/en not_active Expired - Fee Related
- 2002-08-07 PL PL02368228A patent/PL368228A1/pl not_active Application Discontinuation
- 2002-08-07 KR KR10-2004-7001959A patent/KR20040035725A/ko not_active Withdrawn
- 2002-08-07 CA CA002456291A patent/CA2456291A1/en not_active Abandoned
- 2002-08-07 HU HU0401187A patent/HUP0401187A2/hu unknown
- 2002-08-07 EP EP02747621A patent/EP1414812B1/en not_active Expired - Lifetime
- 2002-08-07 DE DE60209354T patent/DE60209354T2/de not_active Expired - Fee Related
- 2002-08-07 IL IL16026602A patent/IL160266A0/xx unknown
- 2002-08-07 WO PCT/GB2002/003656 patent/WO2003014101A1/en not_active Ceased
- 2002-08-07 BR BR0211780-0A patent/BR0211780A/pt not_active IP Right Cessation
2004
- 2004-02-06 NO NO20040551A patent/NO20040551L/no not_active Application Discontinuation
- 2004-03-08 ZA ZA200401873A patent/ZA200401873B/en unknown

Also Published As

Publication number	Publication date
NO20040551L (no)	2004-05-10
CN1568320A (zh)	2005-01-19
IL160266A0 (en)	2004-07-25
NZ531521A (en)	2005-06-24
US20040192733A1 (en)	2004-09-30
PT1414812E (pt)	2006-05-31
US7015234B2 (en)	2006-03-21
EA200400287A1 (ru)	2004-06-24
BR0211780A (pt)	2004-07-27
CA2456291A1 (en)	2003-02-20
MXPA04001212A (es)	2004-07-08
DE60209354T2 (de)	2006-10-19
CN1275954C (zh)	2006-09-20
EA006877B1 (ru)	2006-04-28
EP1414812A1 (en)	2004-05-06
ES2257561T3 (es)	2006-08-01
JP2005501090A (ja)	2005-01-13
WO2003014101A1 (en)	2003-02-20
GB0119396D0 (en)	2001-10-03
HUP0401187A2 (hu)	2004-12-28
ATE318263T1 (de)	2006-03-15
ZA200401873B (en)	2005-03-08
KR20040035725A (ko)	2004-04-29
EP1414812B1 (en)	2006-02-22
DE60209354D1 (de)	2006-04-27

Legal Events

Date	Code	Title	Description
2010-12-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
GB0124933D0 (en)	2001-12-05	Chemical compounds
MXPA05011411A (es)	2006-05-31	1,4-diazepinas sustituidas y usos de las mismas.
IL165262A (en)	2011-10-31	Kinase inhibitors and pharmaceutical compositions containing them
SE0202483D0 (sv)	2002-08-21	Chemical compounds
SE9903760D0 (sv)	1999-10-18	New compounds
PL369108A1 (pl)	2005-04-18	Inhibitory dehydrogenazy 17 beta-hydroksysteroidowej typu 3 do leczenia chorób zależnych od androgenu
FI964815A0 (fi)	1996-12-02	Piperatsiinijohdoksia 5-HT1A antagonisteina
EP1340755A4 (en)	2004-03-17	AGENT WITH EFFECT AGAINST HELICOBACTER
MXPA03009750A (es)	2004-06-30	Compuestos quimicos.
PL378555A1 (pl)	2006-05-02	Sulfonoamido-podstawione pochodne ksantyny do stosowania jako inhibitory PEPCK
IL149586A0 (en)	2002-11-10	Pyrimidine derivatives as selective inhibitors of cox-2
AU2001266575A1 (en)	2002-01-08	Chemical compounds
ZA200404752B (en)	2005-04-26	6-aminomorphinane derivatives method for the production and use thereof
AU2001263278A1 (en)	2002-01-08	Cyclic gmp-specific phosphodiesterase inhibitors
SE9803773D0 (sv)	1998-11-05	Compounds
MXPA02004441A (es)	2004-09-10	Derivados de isoxazol como inhibidores de la fosfodiesterasa.
GB0112810D0 (en)	2001-07-18	Pyrimidine derivatives
AU2001296699A1 (en)	2002-05-21	Condensed pyrazindione derivatives as pde inhibitors
TW200505906A (en)	2005-02-16	Selective mmp-13 inhibitors
PL335012A1 (en)	2000-02-28	Novel derivatives of indan-1-ole, method of obtaining and composition containing them
GB0119396D0 (en)	2001-10-03	Hydroxamic acid derivatives
AU2001244999A1 (en)	2001-10-23	Naphthamide neurokinin antagonists for use as medicaments
PT1049670E (pt)	2002-12-31	Derivados de azetidinocarboxamida para o tratamento de perturbacoes do snc
MXPA04004685A (es)	2004-08-12	Procedimientos para preparar inhibidores de tipo-1 de intercambiador sodio-hidrogeno.
SE9901530D0 (sv)	1999-04-28	Novel compounds