PL3686211T3 - Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej - Google Patents

Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej

Info

Publication number
PL3686211T3
PL3686211T3 PL20152200.0T PL20152200T PL3686211T3 PL 3686211 T3 PL3686211 T3 PL 3686211T3 PL 20152200 T PL20152200 T PL 20152200T PL 3686211 T3 PL3686211 T3 PL 3686211T3
Authority
PL
Poland
Prior art keywords
oligoscarides
hmos
human milk
effectively purifying
neutral human
Prior art date
Application number
PL20152200.0T
Other languages
English (en)
Inventor
Stefan Jennewein
Original Assignee
Chr. Hansen HMO GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49949589&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3686211(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chr. Hansen HMO GmbH filed Critical Chr. Hansen HMO GmbH
Publication of PL3686211T3 publication Critical patent/PL3686211T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Pediatric Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Husbandry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dairy Products (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL20152200.0T 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej PL3686211T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14151737.5A EP2896628B1 (en) 2014-01-20 2014-01-20 Process for efficient purification of neutral human milk oligosaccharides (HMOs) from microbial fermentation

Publications (1)

Publication Number Publication Date
PL3686211T3 true PL3686211T3 (pl) 2023-06-05

Family

ID=49949589

Family Applications (4)

Application Number Title Priority Date Filing Date
PL14151737T PL2896628T3 (pl) 2014-01-20 2014-01-20 Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
PL19215076.1T PL3680249T3 (pl) 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej
PL14827224T PL3131912T3 (pl) 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania z neutralnych oligosacharydów mleka ludzkiego (HMO) w mikrobiologicznej fermentacji
PL20152200.0T PL3686211T3 (pl) 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej

Family Applications Before (3)

Application Number Title Priority Date Filing Date
PL14151737T PL2896628T3 (pl) 2014-01-20 2014-01-20 Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
PL19215076.1T PL3680249T3 (pl) 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej
PL14827224T PL3131912T3 (pl) 2014-01-20 2014-12-23 Sposób skutecznego oczyszczania z neutralnych oligosacharydów mleka ludzkiego (HMO) w mikrobiologicznej fermentacji

Country Status (18)

Country Link
US (4) US10377787B2 (pl)
EP (5) EP2896628B1 (pl)
JP (2) JP6901857B2 (pl)
KR (1) KR102137027B1 (pl)
CN (1) CN106132977B (pl)
AT (2) AT17271U1 (pl)
AU (1) AU2014377374B2 (pl)
BR (1) BR112016016705A8 (pl)
CZ (2) CZ35289U1 (pl)
DE (2) DE202014011399U1 (pl)
DK (6) DK2896628T3 (pl)
ES (4) ES2701163T3 (pl)
FI (2) FI3686211T3 (pl)
MX (2) MX394692B (pl)
PH (2) PH12016501421B1 (pl)
PL (4) PL2896628T3 (pl)
RU (1) RU2682445C2 (pl)
WO (1) WO2015106943A1 (pl)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2896628T3 (pl) 2014-01-20 2019-03-29 Jennewein Biotechnologie Gmbh Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
US10500221B2 (en) 2014-12-05 2019-12-10 Glycom A/S Crystalline difucosyllactose
EP3141610A1 (en) 2015-09-12 2017-03-15 Jennewein Biotechnologie GmbH Production of human milk oligosaccharides in microbial hosts with engineered import / export
ES3011213T3 (en) 2015-12-18 2025-04-07 Glycom As Fermentative production of oligosaccharides
ES2991621T3 (es) 2016-03-07 2024-12-04 Glycom As Separación de oligosacáridos de caldo de fermentación
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
EP3645545A4 (en) * 2017-06-30 2021-05-05 Glycom A/S PURIFICATION OF OLIGOSACCHARIDES
CN119655445A (zh) 2017-07-12 2025-03-21 格礼卡姆股份公司 包含中性单糖或寡糖和酸性非碳水化合物组分的无定形混合物
EP3450443A1 (en) * 2017-08-29 2019-03-06 Jennewein Biotechnologie GmbH Process for purifying sialylated oligosaccharides
US11377462B2 (en) 2017-09-29 2022-07-05 Frieslandcampina Nederland B.V. Process for the purification of a neutral human milk oligosaccharide (HMO) from microbial fermentation
EP3486326A1 (en) * 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Method for the purification of n-acetylneuraminic acid from a fermentation broth
BR112020011242A2 (pt) * 2017-12-08 2020-11-17 Jennewein Biotechnologie Gmbh mistura seca por pulverização de oligossacarídeos de leite humano
ES3039971T3 (en) 2017-12-08 2025-10-28 Chr Hansen Hmo Gmbh Spray-dried 3-fucosyllactose
EP3494807A1 (en) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Spray-dried sialyllactose
PL3494806T3 (pl) 2017-12-08 2025-10-06 Chr. Hansen HMO GmbH Suszona rozpyłowo lakto-n-fukopentaoza
PL3494805T3 (pl) 2017-12-08 2025-10-06 Chr. Hansen HMO GmbH Suszone rozpyłowo tetrasacharydy
DK3524067T3 (da) * 2018-02-08 2025-05-19 Chr Hansen Hmo Gmbh Spraytørret blanding af modermælksoligosaccharider
EP3546060A1 (en) * 2018-03-27 2019-10-02 DuPont Nutrition Biosciences ApS Process for spray drying fucosyllactose solutions and related product compositions
CN112074196A (zh) * 2018-05-07 2020-12-11 詹尼温生物技术有限责任公司 从微生物发酵获得的碳水化合物中纯化乳-N-新四糖(LNnT)的简单方法
BR112020023639A2 (pt) * 2018-05-23 2021-02-17 Dsm Ip Assets B.V. produção de oligossacarídeos
MX2020012855A (es) * 2018-06-01 2021-02-17 Jennewein Biotechnologie Gmbh Proceso sencillo para la purificacion de una sialilactosa.
CN109111043B (zh) * 2018-09-16 2021-11-09 苏州渭中科技发展有限公司 一种高盐高cod废水的处理方法
SG11202106234SA (en) 2018-12-19 2021-07-29 Basf Se Method for separating biomass from a solution comprising biomass and at least one oligosaccaride
PT3897902T (pt) 2018-12-19 2023-12-06 Glycom As Separação de oligossacáridos
EP3914602A4 (en) * 2019-01-21 2022-12-07 DuPont Nutrition Biosciences ApS PROCESS FOR THE PRODUCTION OF L-FUCOSE
EP3686210A1 (en) * 2019-01-24 2020-07-29 DuPont Nutrition Biosciences ApS Process for purifying a human milk oligosaccharide and related compositions
BE1027078A9 (nl) * 2019-02-25 2020-09-28 Nutribam Bvba Samenstelling, voedingssupplement en werkwijze voor het ondersteunen en/of verbeteren van de darmgezondheid
US20220022515A1 (en) 2019-02-25 2022-01-27 Nutribam Bv Composition, Food Supplement and Method for Supporting and/or Improving Intestinal Health
EP3741770A1 (en) 2019-05-21 2020-11-25 Jennewein Biotechnologie GmbH Purification of oligosaccharides from a fermentation broth by using filtration
PL3979827T3 (pl) * 2019-06-04 2024-01-15 N.V. Nutricia Kompozycja żywieniowa zawierająca 2'fukozylolaktozę i 3'galaktozylolaktozę
EP3750902A1 (en) 2019-06-14 2020-12-16 Jennewein Biotechnologie GmbH Process for the purification of lacto-n-neotetraose
CN114615896A (zh) * 2019-09-04 2022-06-10 杜邦营养生物科学有限公司 从包含人乳寡糖和相关组合物的溶液中去除消泡剂的方法
EP3822282A1 (en) * 2019-11-18 2021-05-19 DuPont Nutrition Biosciences ApS Process for removing an antifoam agent from a solution comprising a human milk oligosaccharide and related compositions
AU2020354581A1 (en) 2019-09-24 2022-03-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
EP4097118A4 (en) * 2020-01-29 2024-02-28 DSM IP Assets B.V. METHOD FOR RECOVERY AND PURIFICATION OF HUMAN MILK OLIGOSACCHARIDES
CN111540125B (zh) * 2020-04-20 2021-01-05 中国人民解放军火箭军工程设计研究院 一种充电桩的充电管理方法、设备及计算机可读存储介质
US20230227487A1 (en) 2020-06-12 2023-07-20 Basf Se Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides
CA3188645A1 (en) 2020-08-14 2022-02-17 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
CN112568439A (zh) * 2020-12-21 2021-03-30 湖北福星生物科技有限公司 一种从微生物发酵液中分离纯化母乳低聚糖的方法及其应用
MX2023008227A (es) 2021-01-12 2023-07-20 Prolacta Bioscience Inc Regimenes de tratamiento simbiotico.
CN112920234B (zh) * 2021-01-27 2022-03-29 南开大学 一种2′-岩藻糖基乳糖的富集纯化方法
DE202022002944U1 (de) 2021-04-30 2024-01-31 DSM IP Assets B.V. Säuglingsnahrung mit niedrigem Arsengehalt
DK181242B1 (en) 2021-05-17 2023-05-30 Dsm Ip Assets Bv GENETICALLY ENGINEERED CELLS COMPRISING A RECOMBINANT NUCLEIC ACID SEQUNCE ENCODING AN α-1,2-FUCOSYLTRANSFERASE CAPABLE OF PRODUCING LNFP-I, NUCLEIC ACID SEQUENCES ENCODING SAME AND METHODS FOR USE OF SAME
BE1029434B1 (nl) 2021-06-15 2023-07-31 Dsm Ip Assets Bv Scheiding van moedermelkoligosachariden uit een fermentatiebouillon
BE1029436B1 (nl) 2021-06-15 2023-07-31 Dsm Ip Assets Bv Scheiding van moedermelkoligosachariden uit een fermentatiebouillon
EP4355465A1 (en) 2021-06-15 2024-04-24 DSM IP Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
WO2022263424A1 (en) 2021-06-15 2022-12-22 Dsm Ip Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
EP4418878A1 (en) 2021-10-18 2024-08-28 DSM IP Assets B.V. A method for providing an amorphous hmo product by drying
CN116200316B (zh) * 2021-11-30 2024-08-06 虹摹生物科技(上海)有限公司 一种基因工程菌及其在制备唾液酸乳糖中的应用
CN114539433B (zh) * 2021-12-29 2022-11-01 北京三元食品股份有限公司 一种乳低聚糖的制备方法及制备的低聚糖粉、食品
EP4502168A1 (en) * 2022-03-25 2025-02-05 Kirin Holdings Kabushiki Kaisha Production method for lactodifucotetraose (ldft)
CN117003803B (zh) * 2022-05-07 2026-05-26 恒睿（青岛）生物科技有限公司 一种三糖的晶型
CN115873051B (zh) 2022-05-17 2024-06-25 山东恒鲁生物科技有限公司 三糖的新晶型
US20250376707A1 (en) 2022-06-14 2025-12-11 Dsm Ip Assets B.V. Separation of human milk oligosaccharides from a fermentation broth
WO2024047096A1 (en) 2022-08-30 2024-03-07 Inbiose N.V. Process for purification of an oligosaccharide
WO2024130119A2 (en) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Synbiotic compositions for short chain fatty acid production
CN115651039A (zh) * 2022-12-27 2023-01-31 保龄宝生物股份有限公司 一种高密度2’-岩藻糖基乳糖的生产方法
CN116425810B (zh) * 2023-06-14 2023-08-11 山东合成远景生物科技有限公司 一种混合液中3-岩藻糖基乳糖的纯化方法
CN117089503B (zh) * 2023-10-17 2024-01-02 保龄宝生物股份有限公司 一种大肠杆菌k-12 mg1655 blbyzt6及其应用
WO2025114343A2 (en) * 2023-11-29 2025-06-05 Frieslandcampina Nederland B.V. Process for the production of human milk oligosaccharides

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61271296A (ja) 1985-05-28 1986-12-01 Kyogyo Kumiai N F I Ｎ−アセチルキトオリゴ糖の製造方法
JPH0614870B2 (ja) * 1986-12-15 1994-03-02 株式会社ヤクルト本社 ガラクトオリゴ糖の製造法
JP2001502005A (ja) 1996-10-10 2001-02-13 サイテル コーポレイション 限外濾過、逆浸透及びナノ濾過を利用する炭水化物の精製
US5945314A (en) 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
US6323008B1 (en) * 1997-08-14 2001-11-27 Neose Technologies, Inc. Methods for producing sialyloligosaccharides in a dairy source
US6017433A (en) 1997-11-12 2000-01-25 Archer Daniels Midland Company Desalting aqueous streams via filled cell electrodialysis
AU1234400A (en) 1998-10-27 2000-05-15 Cargill Incorporated Method for purifying a polyol product stream
DE19906865C2 (de) 1999-02-18 2003-03-13 Infineon Technologies Ag Verfahren und Einrichtung zur Entzerrung und Decodierung eines Datensignals
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
FR2799754A1 (fr) 1999-10-18 2001-04-20 Roquette Freres Procede de separation et de purification d'acide lactique a partir d'un milieu de fermentation
US6288222B1 (en) 2000-02-16 2001-09-11 Neose Technologies, Inc. Method of filtration of a dairy stream
US6618584B1 (en) 2000-08-30 2003-09-09 Telefonaktiebolaget Lm Ericsson (Publ) Terminal authentication procedure timing for data calls
JP2003047402A (ja) * 2001-08-06 2003-02-18 Meiji Milk Prod Co Ltd 中性オリゴ糖含有育児用調製乳
JP2003048901A (ja) 2001-08-09 2003-02-21 Oji Paper Co Ltd 長鎖キシロオリゴ糖組成物およびその製造方法
FR2844209B1 (fr) 2002-09-06 2007-10-19 Applexion Ste Nouvelle De Rech Procede de purification par nanofiltration d'une solution aqueuse sucree contenant des anions et cations monovalents et polyvalents
US7919658B2 (en) 2003-05-06 2011-04-05 E. I. Du Pont De Nemours And Company Purification of biologically-produced 1,3-propanediol
PL1644482T5 (pl) * 2003-06-30 2015-05-29 Clasado Inc Nowa kompozycja galaktooligosacharydów i jej wytwarzanie
US20080145899A1 (en) 2004-09-17 2008-06-19 Neose Technologies Inc Production of Oligosaccharides By Microorganisms
CA2580529A1 (en) * 2004-10-01 2006-04-13 Eisai R & D Management Co., Ltd. Fine particle-containing composition and manufacturing method therefor
CA2597499A1 (en) 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Recombinant microorganisms in fermentative production of vitamin c and a process thereof
US20070256936A1 (en) 2006-05-04 2007-11-08 Robert Jansen Method for Deashing Syrup by Electrodialysis
JPWO2009008362A1 (ja) 2007-07-12 2010-09-09 よつ葉乳業株式会社 シアル酸化合物含有組成物の製造方法
WO2010070104A1 (en) 2008-12-19 2010-06-24 Jennewein Biotechnologie Gmbh Synthesis of fucosylated compounds
GB0904562D0 (en) * 2009-03-17 2009-04-29 Separation Technologies Invest Isolation and purification of components of whey
EP2417144B1 (en) 2009-04-07 2017-08-23 Glycom A/S Synthesis of 2'-o-fucosyllactose
MX2011013231A (es) * 2009-06-08 2012-01-20 Jennewein Biotechnologie Gmbh Sintesis de hmo.
JP2012532195A (ja) * 2009-07-06 2012-12-13 チルドレンズ ホスピタル メディカル センター 乳オリゴ糖による炎症の阻害
IT1395068B1 (it) 2009-08-07 2012-09-05 Inalco Spa Processo per la produzione di galatto-oligosaccaridi ultrapuri
CN101691538B (zh) 2009-09-29 2012-05-09 保龄宝生物股份有限公司 一种米曲霉菌种及其制备高纯度低聚半乳糖的方法
CA2786710C (en) * 2010-01-19 2018-10-09 Abbott Laboratories Nutritional formulas containing synbiotics
EP2576578B1 (en) 2010-06-01 2018-09-19 Glycom A/S Polymorphs of 2'-o-fucosyllactose and producing thereof
EP2439264B1 (en) 2010-10-11 2015-06-03 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
EP2455387A1 (en) 2010-11-23 2012-05-23 Nestec S.A. Oligosaccharide mixture and food product comprising this mixture, especially infant formula
EP3338784B1 (en) 2010-12-31 2020-07-22 Abbott Laboratories Human milk oligosaccharides for modulating inflammation
TW201233340A (en) * 2010-12-31 2012-08-16 Abbott Lab Human milk oligosaccharides for modulating inflammation
BR112013016929A2 (pt) * 2010-12-31 2019-09-24 Abbott Lab oligossacarídeos de leite humano para promover o crescimento de bactérias benéficas
CN102154163A (zh) 2010-12-31 2011-08-17 朱莉 一种3′-唾液酸乳糖的制备方法
EP2479263B1 (en) 2011-01-20 2013-11-27 Jennewein Biotechnologie GmbH Novel Fucosyltransferases and their applications
EP2675899A4 (en) * 2011-02-16 2014-09-10 Glycosyn LLC BIOSYNTHESIS OF HUMAN MILK OLIGOSACCHARIDES IN MANIPULATED BACTERIA
CN102095181A (zh) 2011-03-16 2011-06-15 黎昌兴 Led强光源流体巡回散热装置
JP6129821B2 (ja) * 2011-05-13 2017-05-17 グリコシン リミテッド ライアビリティー カンパニー プレバイオティクスとしての、精製された２’−フコシルラクトース、３−フコシルラクトース、およびラクトジフコテトラオースの使用
EP2526784A1 (en) 2011-05-24 2012-11-28 Nestec S.A. Milk oligosaccharide-galactooligosaccharide composition for infant formula containing the soluble oligosaccharide fraction present in milk, and having a low level of monosaccharides, and a process to produce the composition
DK2722394T3 (en) * 2011-06-07 2018-06-18 Hero Ag OBJECTIVES OF OLIGOSACCHARIDES BY A BIOTECHNOLOGICAL PROCEDURE
NL2007268C2 (en) * 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
JP6017133B2 (ja) * 2011-12-12 2016-10-26 Ｍｃフードスペシャリティーズ株式会社 風味改良剤
CA3152828A1 (en) 2011-12-19 2013-06-27 The Coca-Cola Company Methods for purifying steviol glycosides and uses of the same
US20150065702A1 (en) 2012-03-20 2015-03-05 Glycom A/S Synthesis of the Trisaccharide 3-O-Fucosyllactose and Intermediates Thereof
EP2859112A4 (en) 2012-06-08 2015-10-28 Glycom As PROCESS FOR THE PREPARATION OF OLIGOSACCHARIDES AND OLIGOSACCHARIDE GLYCOSIDES BY FERMENTATION
DE202013012829U1 (de) 2012-06-14 2020-03-04 Glycom A/S Verbesserung der Stabilität und Reinheit sowie Erhöhung der Bioverfügbarkeit von menschlichen Milch-Oligosacchariden oder Vorläufern oder Mischungen davon
ITFI20120143A1 (it) * 2012-07-12 2014-01-13 Inalco S A S Di Giovanni Cipollett I & C Polimorfi idrati e anidri del 2'-o-fucosillattosio e loro metodi di produzione.
US9029136B2 (en) 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
WO2014086373A1 (en) 2012-12-07 2014-06-12 Glycom A/S Crystallisation of human milk oligosaccharides (hmo)
ES2875327T3 (es) 2013-09-10 2021-11-10 Chr Hansen Hmo Gmbh Producción de oligosacáridos
CN103468766B (zh) 2013-09-18 2015-07-01 恩施天天佳生物科技有限公司 一种高纯度甘露低聚糖的制备方法
EP2857410A1 (en) * 2013-10-04 2015-04-08 Jennewein Biotechnologie GmbH Process for purification of 2´-fucosyllactose using simulated moving bed chromatography
PL2896628T3 (pl) 2014-01-20 2019-03-29 Jennewein Biotechnologie Gmbh Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
DK2927316T3 (en) 2014-03-31 2019-03-04 Jennewein Biotechnologie Gmbh Total fermentation of oligosaccharides
US20170044538A1 (en) 2014-04-17 2017-02-16 Biogen Ma Inc. Compositions and Methods for Modulation of SMN2 Splicing in a Subject
ES2968677T3 (es) 2014-06-11 2024-05-13 Glycom As Separación de 2’-O-fucosil-lactosa de caldo de fermentación
EP3141610A1 (en) 2015-09-12 2017-03-15 Jennewein Biotechnologie GmbH Production of human milk oligosaccharides in microbial hosts with engineered import / export

Also Published As

Publication number Publication date
PH12016501421A1 (en) 2016-08-22
ES2942630T3 (es) 2023-06-05
FI3686211T3 (fi) 2023-04-26
AT17418U1 (de) 2022-03-15
DE202014011358U1 (de) 2019-09-26
ES2942586T3 (es) 2023-06-02
US20160333042A1 (en) 2016-11-17
DK3686211T3 (da) 2023-04-24
EP3680249B1 (en) 2023-03-01
PH12020500199A1 (en) 2021-03-15
DK3131912T3 (da) 2020-02-10
DK201900054Y4 (da) 2019-09-26
PL3131912T3 (pl) 2020-06-15
EP3686211A2 (en) 2020-07-29
US20190177352A1 (en) 2019-06-13
EP3686211A3 (en) 2021-01-20
CZ35288U1 (cs) 2021-08-03
DK201900054U1 (en) 2019-07-02
ES2779414T3 (es) 2020-08-17
DK201900072U1 (en) 2019-09-27
MX369375B (es) 2019-11-07
JP2020014482A (ja) 2020-01-30
KR20160132009A (ko) 2016-11-16
RU2016128955A3 (pl) 2018-05-21
CN106132977A (zh) 2016-11-16
KR102137027B1 (ko) 2020-07-23
CZ35289U1 (cs) 2021-08-03
US20200231618A1 (en) 2020-07-23
EP3680249A2 (en) 2020-07-15
WO2015106943A1 (en) 2015-07-23
DK3680249T3 (da) 2023-04-24
US20210061836A1 (en) 2021-03-04
US10377787B2 (en) 2019-08-13
JP7000396B2 (ja) 2022-02-10
MX2016009394A (es) 2017-02-08
EP2896628B1 (en) 2018-09-19
EP3680249A3 (en) 2021-01-20
EP3375786A1 (en) 2018-09-19
JP6901857B2 (ja) 2021-07-14
RU2016128955A (ru) 2018-02-26
MX2019013267A (es) 2020-01-13
EP3131912A1 (en) 2017-02-22
EP3131912B1 (en) 2020-01-22
DK2896628T3 (en) 2019-01-14
US10882880B2 (en) 2021-01-05
PH12016501421B1 (en) 2016-08-22
JP2017506065A (ja) 2017-03-02
MX394692B (es) 2025-03-24
AU2014377374A1 (en) 2016-08-04
ES2701163T3 (es) 2019-02-21
BR112016016705A2 (pl) 2017-08-08
BR112016016705A8 (pt) 2022-10-11
PL2896628T3 (pl) 2019-03-29
EP3686211B1 (en) 2023-03-01
AT17271U1 (de) 2021-10-15
EP2896628A1 (en) 2015-07-22
DE202014011399U1 (de) 2020-02-12
CN106132977B (zh) 2020-05-12
AU2014377374B2 (en) 2019-07-04
PL3680249T3 (pl) 2023-05-15
US11597740B2 (en) 2023-03-07
FI3680249T3 (fi) 2023-04-25
RU2682445C2 (ru) 2019-03-19
US11661435B2 (en) 2023-05-30

Similar Documents

Publication Publication Date Title
PL3680249T3 (pl) Sposób skutecznego oczyszczania neutralnych oligosacharydów mleka ludzkiego (hmos) z fermentacji mikrobiologicznej
IL285965A (en) Ex vivo organ care system
PL3102314T3 (pl) Membrana do oczyszczania krwi
IL243115A0 (en) A system and method for growing crops and components therefor
PT3427814T (pt) Hemodialisador para purificação de sangue
LT3174394T (lt) Augalo inokuliavimo būdas
EP3087036A4 (en) Method for biological purification of water
EP3238761A4 (en) Blood treatment system
EP3248629A4 (en) Blood purification device
EP3162392A4 (en) Blood purification device
EP3287159A4 (en) Blood purification apparatus
EP3128932C0 (en) CANNULA FOR CONNECTING MEDICAL DEVICES TO BIOLOGICAL SYSTEMS
DK3094640T3 (da) Fremgangsmåder til steril kromatografi og fremstilling
EP3144022A4 (en) Blood purification device
IL254883A0 (en) A method for protein purification
EP3238754A4 (en) Blood purification system
EP3269408A4 (en) Blood purification device
EP3192542A4 (en) Blood purification device
EP3149471C0 (en) USE OF BLOOD CULTURE PLATFORMS FOR MILK STERILITY TESTING
EP3269407A4 (en) Blood purification device
PL3160913T3 (pl) Sposób oczyszczania osadu biologicznego
PL4159692T3 (pl) Sposób biologicznego oczyszczania ścieków
DK3342853T3 (da) Tarmbakterier butyribacter intestini
EP3144021A4 (en) Blood purification device
PL3146044T3 (pl) Sposób immobilizacji lipazy