PL369010A1 - Sposoby, kompozycje i zestawy dotyczące chitynaz i chitynopodobnych cząsteczek oraz choroby zapalnej - Google Patents

Sposoby, kompozycje i zestawy dotyczące chitynaz i chitynopodobnych cząsteczek oraz choroby zapalnej

Info

Publication number
PL369010A1
PL369010A1 PL02369010A PL36901002A PL369010A1 PL 369010 A1 PL369010 A1 PL 369010A1 PL 02369010 A PL02369010 A PL 02369010A PL 36901002 A PL36901002 A PL 36901002A PL 369010 A1 PL369010 A1 PL 369010A1
Authority
PL
Poland
Prior art keywords
chitinases
chitinase
molecules
compositions
methods
Prior art date
Application number
PL02369010A
Other languages
English (en)
Inventor
Jack A. Elias
Zhou Zhu
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of PL369010A1 publication Critical patent/PL369010A1/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2434Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2442Chitinase (3.2.1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01014Chitinase (3.2.1.14)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/81Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
PL02369010A 2001-07-24 2002-07-23 Sposoby, kompozycje i zestawy dotyczące chitynaz i chitynopodobnych cząsteczek oraz choroby zapalnej PL369010A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30743201P 2001-07-24 2001-07-24

Publications (1)

Publication Number Publication Date
PL369010A1 true PL369010A1 (pl) 2005-04-18

Family

ID=23189747

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02369010A PL369010A1 (pl) 2001-07-24 2002-07-23 Sposoby, kompozycje i zestawy dotyczące chitynaz i chitynopodobnych cząsteczek oraz choroby zapalnej

Country Status (13)

Country Link
US (6) US7214373B2 (pl)
EP (1) EP1418813A4 (pl)
JP (1) JP2006508014A (pl)
KR (1) KR20040053100A (pl)
AU (1) AU2002319680B2 (pl)
BR (1) BR0211468A (pl)
CA (1) CA2454342A1 (pl)
HU (1) HUP0400659A3 (pl)
IL (2) IL160000A0 (pl)
MX (1) MXPA04000769A (pl)
NO (1) NO20040330L (pl)
PL (1) PL369010A1 (pl)
WO (1) WO2003009808A2 (pl)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1488233A4 (en) * 2001-10-09 2006-06-21 Genentech Inc NEW ACID MUDE PROTEINS AND THESE CODING POLYNUCLEOTIDES
US20040170621A1 (en) * 2002-08-30 2004-09-02 Roodman G. David Method of resisting osteoclast formation
US7364846B2 (en) * 2002-10-11 2008-04-29 Molecular Devices Corporation Gene expression profiling from FFPE samples
WO2004092404A2 (en) * 2003-04-11 2004-10-28 Wyeth Inhibitors of acidic mammalian chitinase as asthma therapeutics
EP1729805A4 (en) * 2004-02-25 2008-11-26 Medimmune Inc METHODS AND COMPOSITIONS RELATED TO CHITINASES AND CHITINASE-MOLECULARS AND MODULATION OF OSTEOCLASTS
KR20080025174A (ko) 2005-06-23 2008-03-19 메디뮨 인코포레이티드 응집 및 단편화 프로파일이 최적화된 항체 제제
WO2007027748A2 (en) * 2005-08-31 2007-03-08 Medimmune, Inc. C/clp antagonists and methods of use thereof
TW200813091A (en) 2006-04-10 2008-03-16 Amgen Fremont Inc Targeted binding agents directed to uPAR and uses thereof
WO2008144646A1 (en) * 2007-05-18 2008-11-27 Wyeth Novel primate chitinases and uses therefor
WO2009092382A1 (en) * 2008-01-23 2009-07-30 Rigshospitalet, Region Hovedstaden Classification of individuals suffering from cardiovascular diseases according to survival prognoses as found by measuring the levels of biomarker ykl-40
JP5346957B2 (ja) 2008-01-23 2013-11-20 ヘルレフ ホスピタル 不特定疾患の汎用マーカーとしてのykl−40
EP2321289A4 (en) * 2008-08-01 2011-11-16 Univ Fraser Simon SELECTIVE GLYCOSIDASE HEMMER AND ITS USE
NZ610356A (en) * 2008-08-28 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2735590A1 (en) * 2008-08-29 2010-03-04 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010028658A1 (en) 2008-09-15 2010-03-18 Herlev Hospital, Region Hovedstaden Ykl-40 as a marker for gastrointestinal cancers
WO2010048347A2 (en) * 2008-10-21 2010-04-29 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ607703A (en) 2008-10-21 2014-09-26 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN102264230B (zh) 2008-11-10 2014-12-10 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
MX2011005379A (es) * 2008-11-22 2011-06-09 Astute Medical Inc Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal.
US7851616B2 (en) * 2008-12-04 2010-12-14 Mingchi University Of Technology Development of asthma therapy with rAAV-mediated AMCase shRNA
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2770393A1 (en) 2009-08-07 2011-02-10 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2496942B1 (en) 2009-11-07 2017-03-22 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP5763098B2 (ja) 2009-12-20 2015-08-12 アスチュート メディカル,インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
PT2666872T (pt) 2010-02-05 2016-07-08 Astute Medical Inc Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal
EP3070474A3 (en) 2010-02-26 2016-12-07 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
IN2012MN02812A (pl) 2010-06-23 2015-05-22 Astute Medical Inc
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
DK2655388T3 (en) 2010-12-23 2016-09-19 Alectos Therapeutics Inc Selective glykosidaseinhibitorer and uses thereof
WO2012129651A1 (en) 2011-03-31 2012-10-04 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
WO2013000086A1 (en) 2011-06-27 2013-01-03 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
ES2734494T3 (es) 2011-12-08 2019-12-10 Astute Medical Inc Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal
EP2820419B1 (en) * 2012-02-27 2020-12-09 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP3563859B1 (en) 2012-08-13 2021-10-13 Cedars-Sinai Medical Center Cardiosphere-derived exosomes for tissue regeneration
WO2014032185A1 (en) 2012-08-31 2014-03-06 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
WO2014032188A1 (en) 2012-08-31 2014-03-06 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
WO2014067003A1 (en) 2012-10-31 2014-05-08 Alectos Therapeutics Inc. Glycosidase inhibitors and uses thereof
TR201807542T4 (tr) 2013-01-17 2018-06-21 Astute Medical Inc Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler.
GB2521675B (en) 2013-12-31 2015-11-11 Houman Taheri Amlashi Generating electricity
EP4494699A3 (en) 2014-10-03 2025-04-30 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
JP6209289B2 (ja) * 2014-10-22 2017-10-04 サントリーホールディングス株式会社 環状ジペプチドを有効成分とする皮膚保湿機能改善剤
US10473671B2 (en) 2014-12-18 2019-11-12 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JPWO2016136991A1 (ja) * 2015-02-27 2017-12-07 味の素株式会社 唾液中マーカータンパク質を用いた低栄養状態の判定方法、及びそれに使用する診断薬
EP3465201A4 (en) 2016-06-06 2020-08-26 Astute Medical, Inc. MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR
WO2019036566A1 (en) 2017-08-17 2019-02-21 Brown University METHODS AND COMPOSITIONS RELATING TO THE TREATMENT OF FIBROSIS
EP3749344A4 (en) 2018-02-05 2022-01-26 Cedars-Sinai Medical Center METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS
JP7267562B2 (ja) * 2018-05-21 2023-05-02 学校法人東京薬科大学 免疫調節作用を有する単球およびその使用方法
CN108926708A (zh) * 2018-07-31 2018-12-04 张家港市第人民医院 过敏性鼻炎小鼠模型复制方法及应用
WO2021203051A1 (en) * 2020-04-03 2021-10-07 Standard Of Care Corporation Aerosolized hyaluronidase and/or 4-methylumbelliferone compositions and methods of using same to treat respiratory diseases or disorders
JP2025534332A (ja) * 2022-09-30 2025-10-15 セダーズ-シナイ メディカル センター 治療用核酸及びその使用方法
WO2025048517A1 (ko) * 2023-08-31 2025-03-06 충북대학교 산학협력단 Chi3l1에 특이적인 인간 단일클론항체를 포함하는 아토피 피부염 예방 또는 치료용 조성물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69010388T2 (de) * 1989-04-27 1994-10-20 Ajinomoto Kk Demethylallosamidin und ein Verfahren zu seiner Herstellung.
JP3063930B2 (ja) * 1991-01-31 2000-07-12 味の素株式会社 アロサミジン化合物及びその製造法
AU7205894A (en) * 1993-06-08 1995-01-03 Neogenix, Inc. Purified natural and synthetic compounds for the treatment of osteoarthritis
CA2164498C (en) 1993-07-09 2007-09-11 Paul A. Price Assay for ykl-40 as a marker for degradation of mammalian connective tissue matrices
US7229770B1 (en) 1998-10-01 2007-06-12 The Regents Of The University Of California YKL-40 as a marker and prognostic indicator for cancers
IL115744A (en) * 1994-10-27 2000-07-16 Akzo Nobel Nv Peptides comprising a subsequence of human cartilage glycoprotein - 39
JP3634891B2 (ja) 1995-04-06 2005-03-30 株式会社海洋バイオテクノロジー研究所 キチナーゼ阻害物質
US5773259A (en) * 1996-03-20 1998-06-30 Smithkline Beecham Corporation Tissue remodeling proteins
US5843449A (en) 1996-03-25 1998-12-01 Akzo Nobel N.V. Proteins and novel peptides derived from autoantigen for use in immunotherapy of autoimmune diseases
EP0828752A4 (en) 1996-03-29 2000-07-26 Smithkline Beecham Corp CHITOTRIOSIDASE
EP0805206A3 (en) * 1996-05-03 1999-09-15 Smithkline Beecham Corporation Human cartilage glycoprotein
US5811535A (en) * 1996-08-09 1998-09-22 Smithkline Beecham Corporation Human cartilege gp39-like gene
IL122233A (en) * 1996-12-06 2001-04-30 Akzo Nobel Nv Method of generating monoclonal antibodies to cell wall and pharmaceutical preparations and diagnostic agents containing them
US6200951B1 (en) 1998-03-12 2001-03-13 Icos Corporation Chitinase chitin-binding fragments
US6060590A (en) * 1998-03-31 2000-05-09 The Regents Of The University Of California Chitinase related proteins and methods of use
BR9912378A (pt) 1998-07-23 2001-04-17 Akzo Nobel Nv Peptìdeo, composição farmacêutica, uso de um ou mais dos peptìdeos, e, composição para diagnóstico.
WO2000004917A2 (en) 1998-07-23 2000-02-03 Akzo Nobel N.V. USE OF HC gp-39 IN IMMUNE DISEASES
JP2000327575A (ja) 1999-05-26 2000-11-28 Teika Seiyaku Kk ジケトピペラジン誘導体含有炎症疾患治療剤および新規なジケトピペラジン誘導体
DE60028407T2 (de) * 1999-11-15 2006-11-02 Takeda Pharmaceutical Co. Ltd. Proteine und für diese kodierende dna
EP1319184B1 (en) 2000-08-14 2007-07-25 N.V. Organon Use of antibodies against specific mhc-peptide complexes
WO2002014341A1 (en) * 2000-08-14 2002-02-21 Human Genome Sciences, Inc. 8 human secreted proteins
DE10046267A1 (de) 2000-09-19 2002-03-28 Bayer Ag Verwendung von Riboflavin und Flavinderivaten als Inhibitoren von Chitinasen
US20030087414A1 (en) * 2001-11-02 2003-05-08 Aerts Johannes Maria Franciscus Gerardus Mammalian mucinase, its recombinant production, and its use in therapy or prophylaxis against diseases in which mucus is involved or infectious diseases
US20040170621A1 (en) * 2002-08-30 2004-09-02 Roodman G. David Method of resisting osteoclast formation
PL1856153T3 (pl) 2005-02-28 2011-06-30 Bio Y As Przeciwciała monoklonalne YKL-40

Also Published As

Publication number Publication date
NO20040330L (no) 2004-03-09
US20090149410A1 (en) 2009-06-11
BR0211468A (pt) 2004-11-23
CA2454342A1 (en) 2003-02-06
US20130136751A1 (en) 2013-05-30
KR20040053100A (ko) 2004-06-23
IL160000A (en) 2010-06-16
WO2003009808A3 (en) 2003-09-04
US8679503B2 (en) 2014-03-25
WO2003009808A2 (en) 2003-02-06
EP1418813A4 (en) 2009-03-04
HUP0400659A2 (hu) 2005-02-28
US20060063728A1 (en) 2006-03-23
JP2006508014A (ja) 2006-03-09
US7214373B2 (en) 2007-05-08
HUP0400659A3 (en) 2005-06-28
MXPA04000769A (es) 2005-09-21
IL160000A0 (en) 2004-06-20
US20030049261A1 (en) 2003-03-13
AU2002319680B2 (en) 2008-04-10
EP1418813A2 (en) 2004-05-19
US20090148539A1 (en) 2009-06-11
US20090162347A1 (en) 2009-06-25

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