PL369470A1 - Pochodne benzotiazolu jako ligandy receptora adenozynowego - Google Patents

Pochodne benzotiazolu jako ligandy receptora adenozynowego

Info

Publication number: PL369470A1
Authority: PL; Poland
Prior art keywords: receptor ligands; adenosine receptor; benzothiazole derivatives; benzothiazole; derivatives
Prior art date: 2001-11-19

Application number

PL02369470A

Other languages

English (en)

Inventor

Alexander Flohr

Roland Jakob-Roetne

Roger David Norcross

Claus Riemer

Original Assignee

F.Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-19

Filing date

2002-11-09

Publication date

2005-04-18

2002-11-09 Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag

2005-04-18 Publication of PL369470A1 publication Critical patent/PL369470A1/pl

Links

102000009346 Adenosine receptors Human genes 0.000 title 1
108050000203 Adenosine receptors Proteins 0.000 title 1
IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title 1
239000003446 ligand Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Psychology (AREA)
Immunology (AREA)
Anesthesiology (AREA)
Addiction (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PL02369470A 2001-11-19 2002-11-09 Pochodne benzotiazolu jako ligandy receptora adenozynowego PL369470A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01127313		2001-11-19

Publications (1)

Publication Number	Publication Date
PL369470A1 true PL369470A1 (pl)	2005-04-18

Family

ID=8179264

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02369470A PL369470A1 (pl)	2001-11-19	2002-11-09	Pochodne benzotiazolu jako ligandy receptora adenozynowego

Country Status (21)

Country	Link
US (1)	US6599901B1 (pl)
EP (1)	EP1448196B1 (pl)
JP (1)	JP4216192B2 (pl)
KR (1)	KR100577109B1 (pl)
CN (1)	CN100346792C (pl)
AR (1)	AR037528A1 (pl)
AT (1)	ATE306265T1 (pl)
AU (1)	AU2002366194B8 (pl)
BR (1)	BR0214221A (pl)
CA (1)	CA2467551A1 (pl)
DE (1)	DE60206652T2 (pl)
ES (1)	ES2249639T3 (pl)
GT (1)	GT200200233A (pl)
MX (1)	MXPA04004683A (pl)
PA (1)	PA8557901A1 (pl)
PE (1)	PE20030715A1 (pl)
PL (1)	PL369470A1 (pl)
RU (1)	RU2295523C2 (pl)
TW (1)	TW200407137A (pl)
UY (1)	UY27543A1 (pl)
WO (1)	WO2003043634A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE521512C2 (sv)	2001-06-25	2003-11-11	Niconovum Ab	Anordning för administrering av en substans till främre delen av en individs munhåla
US6727247B2 (en) *	2001-12-10	2004-04-27	Hoffman-La Roche Inc.	Substituted benzothiazole amide derivatives
PT1578422E (pt)	2002-12-20	2007-06-14	Niconovum Ab	Material particulado contendo nicotina fisicamente e quimicamente estável
RU2006112847A (ru)	2003-09-19	2007-11-10	Ф. Хоффманн-Ля Рош Аг (Ch)	Производные тиазолопиридина в качестве лигандов аденозинового рецептора
EP1677791A4 (en)	2003-10-31	2007-08-15	Takeda Pharmaceutical	NITROGENIC CONDENSED HETEROCYCLIC COMPOUNDS
CN1989117B (zh) *	2004-07-22	2011-01-19	弗·哈夫曼-拉罗切有限公司	取代的苯并噻唑
JP5202946B2 (ja) *	2004-07-22	2013-06-05	エフ．ホフマン−ラロシュアーゲー	ベンゾチアゾール誘導体
ES2273599B1 (es) *	2005-10-14	2008-06-01	Universidad De Barcelona	Compuestos para el tratamiento de la fibrilacion auricular.
AU2007224584A1 (en)	2006-03-16	2007-09-20	Niconovum Ab	Improved snuff composition
WO2008063301A2 (en) *	2006-10-11	2008-05-29	Alpharma, Inc.	Pharmaceutical compositions
CA2682494C (en) *	2007-04-04	2011-10-11	Merck & Co., Inc.	Hexahydro-1h-4,7-methanoisoindole-1,3-dione compounds for treating psychiatric disorders
US9549909B2 (en)	2013-05-03	2017-01-24	The Katholieke Universiteit Leuven	Method for the treatment of dravet syndrome
WO2017112701A1 (en)	2015-12-22	2017-06-29	Zogenix International Limited	Metabolism resistant fenfluramine analogs and methods of using the same
ES3024232T3 (en)	2015-12-22	2025-06-04	Zogenix International Ltd	Fenfluramine compositions and methods of preparing the same
SG11201900975XA (en)	2016-08-24	2019-03-28	Zogenix International Ltd	Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same
US10682317B2 (en)	2017-09-26	2020-06-16	Zogenix International Limited	Ketogenic diet compatible fenfluramine formulation
WO2019216919A1 (en)	2018-05-11	2019-11-14	Zogenix International Limited	Compositions and methods for treating seizure-induced sudden death
EP3806835A1 (en) *	2018-06-14	2021-04-21	Zogenix International Limited	Compositions and methods for treating respiratory depression with fenfluramine
EA202191079A1 (ru)	2018-11-19	2021-09-20	Зодженикс Интернэшнл Лимитед	Способы лечения синдрома ретта с применением фенфлурамина
DE102019110904B4 (de)	2019-04-26	2022-01-20	Helmholtz-Zentrum Dresden - Rossendorf E. V.	N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung
US11612574B2 (en)	2020-07-17	2023-03-28	Zogenix International Limited	Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3374550D1 (en)	1982-12-21	1987-12-23	Johnsen Jorgensen Plastics Ltd	Dispensing container
IL90337A0 (en) *	1988-05-24	1989-12-15	Pfizer	Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
AU2001281817B2 (en) *	2000-06-21	2005-11-24	F. Hoffmann-La Roche Ag	Benzothiazole derivatives

2002
- 2002-11-05 US US10/288,531 patent/US6599901B1/en not_active Expired - Fee Related
- 2002-11-09 EP EP02803360A patent/EP1448196B1/en not_active Expired - Lifetime
- 2002-11-09 MX MXPA04004683A patent/MXPA04004683A/es active IP Right Grant
- 2002-11-09 CN CNB028228901A patent/CN100346792C/zh not_active Expired - Fee Related
- 2002-11-09 DE DE60206652T patent/DE60206652T2/de not_active Expired - Fee Related
- 2002-11-09 JP JP2003545315A patent/JP4216192B2/ja not_active Expired - Fee Related
- 2002-11-09 BR BR0214221-0A patent/BR0214221A/pt not_active IP Right Cessation
- 2002-11-09 ES ES02803360T patent/ES2249639T3/es not_active Expired - Lifetime
- 2002-11-09 AT AT02803360T patent/ATE306265T1/de not_active IP Right Cessation
- 2002-11-09 RU RU2004118423/04A patent/RU2295523C2/ru not_active IP Right Cessation
- 2002-11-09 WO PCT/EP2002/012543 patent/WO2003043634A1/en not_active Ceased
- 2002-11-09 KR KR1020047007646A patent/KR100577109B1/ko not_active Expired - Fee Related
- 2002-11-09 PL PL02369470A patent/PL369470A1/pl not_active Application Discontinuation
- 2002-11-09 CA CA002467551A patent/CA2467551A1/en not_active Abandoned
- 2002-11-09 AU AU2002366194A patent/AU2002366194B8/en not_active Ceased
- 2002-11-14 PA PA20028557901A patent/PA8557901A1/es unknown
- 2002-11-14 TW TW091133382A patent/TW200407137A/zh unknown
- 2002-11-15 AR ARP020104398A patent/AR037528A1/es not_active Application Discontinuation
- 2002-11-15 PE PE2002001103A patent/PE20030715A1/es not_active Application Discontinuation
- 2002-11-18 UY UY27543A patent/UY27543A1/es not_active Application Discontinuation
- 2002-11-18 GT GT200200233A patent/GT200200233A/es unknown

Also Published As

Publication number	Publication date
BR0214221A (pt)	2004-09-21
PA8557901A1 (es)	2003-06-30
DE60206652T2 (de)	2006-06-22
ATE306265T1 (de)	2005-10-15
PE20030715A1 (es)	2003-08-29
AU2002366194B8 (en)	2006-11-16
KR20050044537A (ko)	2005-05-12
CA2467551A1 (en)	2003-05-30
JP4216192B2 (ja)	2009-01-28
EP1448196B1 (en)	2005-10-12
TW200407137A (en)	2004-05-16
CN1589146A (zh)	2005-03-02
EP1448196A1 (en)	2004-08-25
AU2002366194B2 (en)	2006-10-26
AU2002366194A1 (en)	2003-06-10
CN100346792C (zh)	2007-11-07
UY27543A1 (es)	2003-05-30
AR037528A1 (es)	2004-11-17
WO2003043634A1 (en)	2003-05-30
GT200200233A (es)	2003-06-17
MXPA04004683A (es)	2004-08-12
JP2005515980A (ja)	2005-06-02
RU2004118423A (ru)	2006-01-10
RU2295523C2 (ru)	2007-03-20
KR100577109B1 (ko)	2006-05-10
US6599901B1 (en)	2003-07-29
ES2249639T3 (es)	2006-04-01
DE60206652D1 (de)	2006-02-23

Legal Events

Date	Code	Title	Description
2010-01-29	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL369470A1 (pl)	2005-04-18	Pochodne benzotiazolu jako ligandy receptora adenozynowego
PL373953A1 (pl)	2005-09-19	Pochodne 7-aminobenzotiazolu jako ligandy receptora adenozynowego
IL161623A0 (en)	2004-09-27	Nicotin-or isonicotin benzothiazole derivatives
PL370978A1 (pl)	2005-06-13	Pochodne benzotiazolu
PL372123A1 (pl)	2005-07-11	Pochodne tiazolu
ZA200309522B (en)	2005-02-23	Substituted cyclohexane-1-4diamine derivatives
IL160701A0 (en)	2004-08-31	3-substituted-4-pyrimidone derivatives
IL162242A0 (en)	2005-11-20	Azaindolylalkylamine derivatives as5-hydroxytryptamine-6 ligands
HUP0303449A3 (en)	2005-02-28	Substituted benzofuran-2-carboxamides derivatives
IL162444A0 (en)	2005-11-20	Triazolo-quinolin derivatives useful as adenosine receptor ligands
PL375416A1 (pl)	2005-11-28	Pochodne tiazolu
HRP20050540A2 (en)	2005-08-31	Imidazoquinoline derivatives as adenosine a3 receptor ligands
HUP0401949A3 (en)	2009-07-28	4-imidazolin-2-one derivatives
HUP0500026A3 (en)	2008-02-28	N-heteroarylnicotinamide derivatives
HUP0303533A3 (en)	2005-02-28	Adenosine a1 agonist adenosine derivatives
AU3167402A (en)	2002-06-24	Aminotriazolopyridiine derivatives as adenosine receptor ligands
PL376897A1 (pl)	2006-01-09	Podstawione 6-(2-chlorowcofenylo) triazolopirymidyny
PL373947A1 (pl)	2005-09-19	Pochodne benzotiazolu
PL1636223T3 (pl)	2008-07-31	Pochodne benzotiazolu jako ligandy receptora adenozynowego
PL370713A1 (pl)	2005-05-30	Heteroarylo-podstawione pochodne aminocykloheksanu
GB0112802D0 (en)	2001-07-18	Pyrimidine derivatives
EP1364954A4 (en)	2009-10-28	Dicarba closo DODECARBORANDERIVATE
GB0112803D0 (en)	2001-07-18	Pyrimidine derivatives
HK1066000A (en)	2005-03-11	Triazolo-quinolin derivatives useful as adenosine receptor ligands
GB0119477D0 (en)	2001-10-03	Pyrimidine derivatives