PL369684A1 - Nowe zastosowanie podstawionych aminometylochromanów - Google Patents

Nowe zastosowanie podstawionych aminometylochromanów

Info

Publication number
PL369684A1
PL369684A1 PL02369684A PL36968402A PL369684A1 PL 369684 A1 PL369684 A1 PL 369684A1 PL 02369684 A PL02369684 A PL 02369684A PL 36968402 A PL36968402 A PL 36968402A PL 369684 A1 PL369684 A1 PL 369684A1
Authority
PL
Poland
Prior art keywords
novel use
substituted aminomethyl
aminomethyl chromans
chromans
substituted
Prior art date
Application number
PL02369684A
Other languages
English (en)
Other versions
PL208787B1 (pl
Inventor
Henning Böttcher
Ralf Devant
Gerd Bartoszyk
Hermann Russ
Frank Weber
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL369684A1 publication Critical patent/PL369684A1/pl
Publication of PL208787B1 publication Critical patent/PL208787B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
PL369684A 2001-09-19 2002-08-12 (2R, 4R/S)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol i (2R, 4R)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol, sposoby ich otrzymywania i zastosowanie do wytwarzania preparatów medycznych oraz zawierająca je kompozycja farmaceutyczna PL208787B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01122377 2001-09-19

Publications (2)

Publication Number Publication Date
PL369684A1 true PL369684A1 (pl) 2005-05-02
PL208787B1 PL208787B1 (pl) 2011-06-30

Family

ID=8178662

Family Applications (1)

Application Number Title Priority Date Filing Date
PL369684A PL208787B1 (pl) 2001-09-19 2002-08-12 (2R, 4R/S)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol i (2R, 4R)-2-({[5-(4-fluorofenylo)-pirydyn-3ylmetylo)]-amino}-metylo)-chroman-4-ol, sposoby ich otrzymywania i zastosowanie do wytwarzania preparatów medycznych oraz zawierająca je kompozycja farmaceutyczna

Country Status (25)

Country Link
US (1) US7618988B2 (pl)
EP (1) EP1427724B1 (pl)
JP (1) JP4615857B2 (pl)
KR (1) KR100912911B1 (pl)
CN (1) CN100338060C (pl)
AR (1) AR036677A1 (pl)
AT (1) ATE325120T1 (pl)
AU (1) AU2002331229B2 (pl)
BR (1) BR0212555A (pl)
CA (1) CA2460696C (pl)
CY (1) CY1105118T1 (pl)
DE (1) DE60211186T2 (pl)
DK (1) DK1427724T3 (pl)
ES (1) ES2262840T3 (pl)
HU (1) HUP0401910A3 (pl)
MX (1) MXPA04002492A (pl)
MY (1) MY128882A (pl)
PE (1) PE20030428A1 (pl)
PL (1) PL208787B1 (pl)
PT (1) PT1427724E (pl)
RU (1) RU2322443C2 (pl)
SI (1) SI1427724T1 (pl)
TW (1) TWI244391B (pl)
WO (1) WO2003024960A1 (pl)
ZA (1) ZA200402855B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10318690B3 (de) * 2003-04-24 2004-11-11 Merck Patent Gmbh Verfahren zur Herstellung von Nicotinaldehyden
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
EP1896021B1 (de) * 2005-06-21 2009-04-15 Merck Patent GmbH Feste pharmazeutische zubereitung enthaltend (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chroman
FR2978916B1 (fr) 2011-08-10 2013-07-26 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
MY169068A (en) * 2012-04-18 2019-02-12 Contera Pharma Aps Orally available pharmaceutical formulation suitable for improved management of movement disorders
FR3001894A1 (fr) 2013-02-08 2014-08-15 Servier Lab Composition pharmaceutique solide pour administration buccale d'agomelatine
CN109689036B (zh) 2016-07-11 2026-06-19 康特拉医药股份有限公司 用于治疗早晨运动不能的脉冲药物输送系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5767132A (en) * 1980-10-07 1982-04-23 Nippon Steel Corp Vertical type continuous annealing furnace having independently moving middle partition plate
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
ATE256130T1 (de) * 1993-08-19 2003-12-15 Janssen Pharmaceutica Nv Gefässverengende dihydrobenzopyranderivate
ES2169102T3 (es) * 1994-10-14 2002-07-01 Merck Patent Gmbh (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central.
US5585388A (en) * 1995-04-07 1996-12-17 Sibia Neurosciences, Inc. Substituted pyridines useful as modulators of acetylcholine receptors
JP3204456B2 (ja) * 1995-12-21 2001-09-04 ファイザー・インコーポレーテッド ２，７―置換オクタヒドロ―ピロロ［１，２―ａ］ピラジン誘導体
US5756521A (en) * 1996-04-03 1998-05-26 American Home Products Corporation Chroman-2-ylmethylamino derivatives
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit

Also Published As

Publication number Publication date
US7618988B2 (en) 2009-11-17
CY1105118T1 (el) 2009-11-04
RU2322443C2 (ru) 2008-04-20
KR20040044461A (ko) 2004-05-28
EP1427724A1 (en) 2004-06-16
SI1427724T1 (sl) 2006-10-31
MXPA04002492A (es) 2004-05-31
BR0212555A (pt) 2004-10-19
CA2460696A1 (en) 2003-03-27
HUP0401910A2 (hu) 2005-01-28
AU2002331229B2 (en) 2008-05-15
ATE325120T1 (de) 2006-06-15
CN1714089A (zh) 2005-12-28
PE20030428A1 (es) 2003-05-24
WO2003024960A1 (en) 2003-03-27
DE60211186D1 (de) 2006-06-08
CA2460696C (en) 2011-01-11
EP1427724B1 (en) 2006-05-03
AR036677A1 (es) 2004-09-29
TWI244391B (en) 2005-12-01
DE60211186T2 (de) 2007-01-18
DK1427724T3 (da) 2006-08-21
ZA200402855B (en) 2005-01-14
CN100338060C (zh) 2007-09-19
ES2262840T3 (es) 2006-12-01
KR100912911B1 (ko) 2009-08-20
RU2004112190A (ru) 2005-05-10
US20060229339A1 (en) 2006-10-12
HUP0401910A3 (en) 2011-02-28
PT1427724E (pt) 2006-09-29
PL208787B1 (pl) 2011-06-30
MY128882A (en) 2007-02-28
JP4615857B2 (ja) 2011-01-19
JP2005527476A (ja) 2005-09-15

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20110812