PL3697209T3 - Kompozycje do regulacji hemolizy i krzepnięcia oraz stabilizacji pęcherzyków zewnątrzkomórkowych - Google Patents

Kompozycje do regulacji hemolizy i krzepnięcia oraz stabilizacji pęcherzyków zewnątrzkomórkowych

Info

Publication number
PL3697209T3
PL3697209T3 PL18867969.0T PL18867969T PL3697209T3 PL 3697209 T3 PL3697209 T3 PL 3697209T3 PL 18867969 T PL18867969 T PL 18867969T PL 3697209 T3 PL3697209 T3 PL 3697209T3
Authority
PL
Poland
Prior art keywords
hemolysis
stabilization
compositions
extracellular vesicles
coagulation regulation
Prior art date
Application number
PL18867969.0T
Other languages
English (en)
Inventor
Nicholas Michael George
Bradford A. Hunsley
Original Assignee
Streck Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Streck Llc filed Critical Streck Llc
Publication of PL3697209T3 publication Critical patent/PL3697209T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/124—Disinfecting agents, e.g. antimicrobials
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Physiology (AREA)
PL18867969.0T 2017-10-19 2018-10-19 Kompozycje do regulacji hemolizy i krzepnięcia oraz stabilizacji pęcherzyków zewnątrzkomórkowych PL3697209T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762574515P 2017-10-19 2017-10-19
PCT/US2018/056747 WO2019079743A1 (en) 2017-10-19 2018-10-19 COMPOSITIONS FOR HEMOLYSIS AND REGULATION OF COAGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES

Publications (1)

Publication Number Publication Date
PL3697209T3 true PL3697209T3 (pl) 2024-11-25

Family

ID=66174254

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18867969.0T PL3697209T3 (pl) 2017-10-19 2018-10-19 Kompozycje do regulacji hemolizy i krzepnięcia oraz stabilizacji pęcherzyków zewnątrzkomórkowych

Country Status (9)

Country Link
US (1) US12378543B2 (pl)
EP (2) EP4427588A3 (pl)
JP (2) JP7293244B2 (pl)
CN (2) CN111372451B (pl)
CA (1) CA3079415A1 (pl)
ES (1) ES2991437T3 (pl)
HU (1) HUE068517T2 (pl)
PL (1) PL3697209T3 (pl)
WO (1) WO2019079743A1 (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
EP3491381B1 (en) 2016-07-29 2025-09-24 Streck LLC Suspension composition for hematology analysis control
JP7293244B2 (ja) 2017-10-19 2023-06-19 ストレック, インコーポレイテッド 溶血、凝固調節および細胞外小胞の安定化のための組成物
CN108865976B (zh) * 2018-07-19 2022-06-28 复旦大学附属中山医院 一种离散汲取收集外泌体(exosome)的方法及试剂
WO2020140035A1 (en) * 2018-12-27 2020-07-02 Streck, Inc. Methods of preparing samples for proteomic analysis
JP7581193B2 (ja) * 2019-05-21 2024-11-12 合同会社H.U.グループ中央研究所 細胞外小胞の洗浄方法
US20220251627A1 (en) * 2019-06-28 2022-08-11 Zymo Research Corporation Compositions for the stabilization of cell-free nucleic acids and methods thereof
CN114450402A (zh) * 2019-09-24 2022-05-06 恰根有限公司 稳定化的含细胞体液样品的多模式分析
WO2021177344A1 (ja) * 2020-03-05 2021-09-10 積水メディカル株式会社 細胞含有液用保存容器及び保存液
EP4139450A1 (en) * 2020-04-20 2023-03-01 SiO2 Medical Products, Inc. Nucleic acid and cell preservative compositions and methods of use
CA3184070A1 (en) * 2020-07-01 2022-01-06 Matthew R. Sobansky Methods of preparing samples for proteomic analysis
CN111961636B (zh) * 2020-07-06 2021-11-26 江苏凯基生物技术股份有限公司 一种外泌体的提取试剂及其应用
EP4196276A1 (en) 2020-08-13 2023-06-21 Streck LLC Sample collection containers, processes and collected samples
CN112575063A (zh) * 2020-12-30 2021-03-30 华南理工大学 一种全血基因组dna保存剂及其制备方法与应用
CN113391060B (zh) * 2021-05-15 2023-08-08 北京北方生物技术研究所有限公司 一种血液样本处理剂及其应用
KR20240013088A (ko) * 2021-05-28 2024-01-30 세키스이 메디칼 가부시키가이샤 혈액 채취 용기, 혈장의 분리 방법, 세포외 유리 핵산의 분리 방법 및 세포외 소포의 분리 방법
WO2023026725A1 (ja) * 2021-08-25 2023-03-02 積水メディカル株式会社 細胞含有液用保存液及び細胞含有液用保存容器
CN118284808A (zh) 2022-03-25 2024-07-02 积水医疗株式会社 循环肿瘤细胞分离试剂盒、循环肿瘤细胞分离容器及循环肿瘤细胞的分离方法
CN115281180A (zh) * 2022-07-04 2022-11-04 四川大学华西医院 一种mRNA-血小板复合物冻存液及其制备方法
EP4356731A1 (en) * 2022-10-19 2024-04-24 Olga Alekseevna Gra Medium and device for collecting, storing and transporting biological samples, as well as their use for the stabilization of extracellular nucleic acids
WO2024192232A1 (en) * 2023-03-14 2024-09-19 Streck Llc Compositions and uses thereof for stabilization of blood sample components
CN121555319B (zh) * 2026-01-21 2026-06-02 宁波大学 一种小球藻外泌体及其mRNA复合纳米颗粒的制备方法和应用

Family Cites Families (266)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1432249A (en) 1922-02-06 1922-10-17 Howard S Borden Article of manufacture
US1922799A (en) 1932-12-16 1933-08-15 George E Gaus Method for affixing identification tags
US2250666A (en) 1938-10-31 1941-07-29 Godefroy Mfg Company Combined label, cap loosener, and auxiliary container
US2690624A (en) 1949-09-15 1954-10-05 Ollie W Phillips Sign
US2930570A (en) 1959-01-30 1960-03-29 Herbert R Leedy Pinch clamp
US3867521A (en) 1970-08-26 1975-02-18 Scherer Corp R P Method for absorption of drugs
US3781120A (en) 1970-09-14 1973-12-25 Technicon Instr Self-locating sample receptacle having integral identification label
US3874384A (en) 1971-11-01 1975-04-01 American Hospital Supply Corp Improved blood storage unit and method of storing blood
US3872730A (en) 1972-03-10 1975-03-25 Becton Dickinson Co Sampling apparatus
US3879295A (en) 1973-08-17 1975-04-22 Eastman Kodak Co Vacutainer with positive separation barrier
US3973913A (en) 1976-01-29 1976-08-10 Louderback Allan Lee Blood control standard
US3994085A (en) 1976-03-29 1976-11-30 Groselak Robert E Baggage tag
US4043453A (en) 1976-05-11 1977-08-23 The Wright Tool & Forge Company Holder and display device for wrench sockets
US4318090A (en) 1980-10-27 1982-03-02 Sensormatic Electronics Corporation Apparatus for deactivating a surveillance tag
US4436821A (en) 1982-04-12 1984-03-13 Streck Laboratories, Inc. Simulated human platelets from red blood cells
US4513522A (en) 1982-09-16 1985-04-30 Selenke William M Label with particular application to laboratory specimen container identification
US4515890A (en) 1982-11-08 1985-05-07 Abbott Laboratories Immunoassay of terminal deoxynucleotidyl transferase
DE8407967U1 (de) 1984-03-15 1984-06-07 Idento - Gesellschaft für industrielle Kennzeichnung mbH, 6074 Rödermark Beschriftbarer Kabelmarkierungsstreifen
US4584219A (en) 1984-11-09 1986-04-22 Baartmans Hans R Web of labels
US4675159A (en) 1985-09-29 1987-06-23 Al Sioufi Habib Method and device for disinfecting biological fluids and container for same
US4818700A (en) 1985-10-25 1989-04-04 Phillips Petroleum Company Pichia pastoris argininosuccinate lyase gene and uses thereof
US5110908A (en) 1986-12-31 1992-05-05 Praxis Biologics, Inc. Haemophilus influenzae peptides and proteins
US4884827A (en) 1988-01-22 1989-12-05 Norfolk Scientific Inc. Partially transparent label
US4921277A (en) 1988-10-24 1990-05-01 Academy Of Applied Science, Inc. Method of labeling needle syringes and medication vials and novel labels therefor
EP0462221A1 (en) 1989-03-07 1991-12-27 Syngene, Inc. In-situ hybridization in suspension for detection or separation of cells
HU201865B (en) 1989-04-28 1991-01-28 Pecsi Dohanygyar Tobacco-smoke filter of high efficiency
US5000484A (en) 1989-08-30 1991-03-19 Phelan James C Identification and monitoring system for surgical specimens
US5153117A (en) 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
JP2540649B2 (ja) 1990-04-27 1996-10-09 テルモ株式会社 採血管
US5250438A (en) 1990-05-09 1993-10-05 Streck Laboratories, Inc. Method for differential determination of white blood cells using diazolidinyl urea to stabilize white blood cells
US5741638A (en) 1990-06-28 1998-04-21 Wakunaga Seiyaku Kabushiki Kaisha Microtiter well for detecting nucleic acid
US5135125A (en) 1991-02-15 1992-08-04 Tapecon, Inc. Hanging label
US5459073A (en) 1991-05-08 1995-10-17 Streck Laboratories, Inc. Method and composition for preserving antigens and process for utilizing cytological material produced by same
US5196182A (en) 1991-05-08 1993-03-23 Streck Laboratories, Inc. Tissue fixative
US5849517A (en) 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5460797A (en) 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
US5260048A (en) 1991-05-08 1993-11-09 Streck Laboratories, Inc. Tissue fixative solution and method
US5270208A (en) 1991-05-09 1993-12-14 Streck Laboratories, Inc. White blood cell hematology control
US5459253A (en) 1991-07-19 1995-10-17 Pharmacia P-L Biochemicals Inc. M-RNA purification
AU645915B2 (en) 1991-07-23 1994-01-27 F. Hoffmann-La Roche Ag Improvements in the in situ PCR
US5343647A (en) 1991-09-03 1994-09-06 Moore Business Forms, Inc. Pressure sensitive pricing tag/label
CA2119554C (en) 1991-09-20 2003-05-06 Gerald W. Camiener Method and compositions with aldehyde stabilizing solution
US5998483A (en) 1991-09-20 1999-12-07 Camiener; Gerald W. Glyoxal-containing preservative compositions
DE4134231A1 (de) 1991-10-16 1993-04-22 Fix Gmbh Gepaeckstreifenanhaenger fuer einzelbeschriftung
US5257633A (en) 1992-06-23 1993-11-02 Becton, Dickinson And Company Surface modified blood collection tubes
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
WO1994002646A1 (en) 1992-07-17 1994-02-03 Aprogenex Inc. Enriching and identyfying fetal cells in maternal blood for in situ hybridization
EP0590327B1 (en) 1992-09-11 2003-04-09 F. Hoffmann-La Roche Ag Detection of nucleic acids in blood
GB9223035D0 (en) 1992-11-03 1992-12-16 Kiessling Cooper Ann A Preservation of peripheral blood & semen in fixatives that inactivate human pathogens
US5688516A (en) 1992-11-12 1997-11-18 Board Of Regents, The University Of Texas System Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices
AU669754B2 (en) 1992-12-18 1996-06-20 Becton Dickinson & Company Barrier coating
US5457024A (en) 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
AU6230594A (en) 1993-02-01 1994-08-29 University Of Iowa Research Foundation, The Quartenary amine surfactants and methods of using same in isolation of rna
EP0708649B1 (en) 1993-07-05 2003-05-28 Sheffield Teaching Hospitals National Health Service Trust Preparation and stabilisation of cells
US6043032A (en) 1993-09-22 2000-03-28 Tosoh Corporation Method of extracting nucleic acids and method of detecting specified nucleic acid sequences
US5429797A (en) 1993-11-10 1995-07-04 Camiener; Gerald W. Safe dialdehydes useful as decontaminants, fixatives, preservatives and embalming agents
AU2274595A (en) 1994-03-29 1995-10-17 Genzyme Corporation Culture and isolation of fetal cells from maternal peripheral blood
EP0754301B1 (en) 1994-04-05 1998-09-09 Northern General Hospital N.H.S. Trust Preparation and stabilisation of cell suspensions
US5501954A (en) 1994-06-13 1996-03-26 Genzyme Corporation Method of detecting cellular material
US5468022A (en) 1994-06-14 1995-11-21 Massachusetts Institute Of Technology Sample tube identification flag
FR2722506B1 (fr) 1994-07-13 1996-08-14 Rhone Poulenc Rorer Sa Composition contenant des acides nucleiques, preparation et utilisations
US5512343A (en) 1994-08-01 1996-04-30 Diagraph Corporation Label assembly
US5540358A (en) 1994-12-19 1996-07-30 The Procter And Gamble Company Flexible planar gusseted package for dispensing a product through a fitment
US5490658A (en) 1995-03-02 1996-02-13 Avery Dennison Corporation Label hangers for intravenous bottles
US5560657A (en) 1995-03-08 1996-10-01 Morgan; Brian R. Tamper-indicating label
USD382343S (en) 1995-06-06 1997-08-12 Home Access Health Corporation Filmstrip for enhancing blood flow
US6527957B1 (en) 1995-08-09 2003-03-04 Baxter International Inc. Methods for separating, collecting and storing red blood cells
US5888822A (en) 1995-10-04 1999-03-30 Hycor Biomedical Inc. Erythrocyte sedimentation rate control
US5817519A (en) 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
EP0929694A4 (en) 1996-03-15 2002-05-02 Penn State Res Found DETECTION OF TUMOR-RELATED EXTRACELLULAR NUCLEIC ACID USING PLASMA OR BLOOD SERUM USING NUCLEIC ACID AMPLIFICATION TESTS
US6630301B1 (en) 1997-03-14 2003-10-07 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum
US6759217B2 (en) 1996-03-26 2004-07-06 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
CA2250118C (en) 1996-03-26 2009-09-29 Michael S. Kopreski Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer
US6072086A (en) 1996-04-12 2000-06-06 Intergen Company Method and composition for controlling formaldehyde fixation by delayed quenching
GB2313288B (en) 1996-05-24 2000-07-12 North Gen Hospital Nhs Trust Specimen collection fluid
IT1294964B1 (it) 1996-07-12 1999-04-23 Domenico Valerio Isolamento e cultura di cellule fetali dal sangue periferico materno
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US5731156A (en) 1996-10-21 1998-03-24 Applied Imaging, Inc. Use of anti-embryonic hemoglobin antibodies to identify fetal cells
US6190609B1 (en) 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US5783093A (en) 1997-01-02 1998-07-21 Haemonetics Corporation Blood cell concentrates using a single solution for anticoagulation and preservation
WO1998031219A1 (en) 1997-01-21 1998-07-23 The American National Red Cross Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light
US6125563A (en) 1997-02-14 2000-10-03 Girerd; Philippe H. Container label with handle flap
GB9704444D0 (en) 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US20010051341A1 (en) 1997-03-04 2001-12-13 Isis Innovation Limited Non-invasive prenatal diagnosis
ATE251306T1 (de) 1997-03-25 2003-10-15 Immunivest Corp Gerät und methoden zum einfnag und zur analyse von partikel-einheiten
CA2285384C (en) 1997-03-28 2012-10-16 Epitope, Inc. Simultaneous collection of dna and non-nucleic analytes from oral fluids
SE514350C2 (sv) 1997-04-07 2001-02-12 Resemino System Ab Metod för affischering samt för metoden anpassat system för affischering
US5939259A (en) 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis
US5906744A (en) 1997-04-30 1999-05-25 Becton Dickinson And Company Tube for preparing a plasma specimen for diagnostic assays and method of making thereof
US5976014A (en) 1997-05-28 1999-11-02 Moore U.S.A., Inc. Integrity seal form/label combination
PT2216416E (pt) 1997-05-30 2012-08-16 Trovagene Inc Métodos para detecção de sequências de ácido nucleico na urina
US6083731A (en) 1997-06-24 2000-07-04 Washington State University Research Foundation Recombinant materials and methods for the production of limonene hydroxylases
JP2002507121A (ja) 1997-06-25 2002-03-05 プロメガ コーポレイション Rnaの単離方法
US6074825A (en) 1997-07-31 2000-06-13 Maine Medical Center Stable encapsulated reference nucleic acid and method of making
US5994078A (en) 1997-07-31 1999-11-30 Maine Medical Center Stable encapsulated reference nucleic acid and method of making
US5962234A (en) 1997-10-20 1999-10-05 Applied Imaging Corporation Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells
CA2260402C (en) 1998-01-22 2001-10-23 Pierre Boisvert Display card
US6210889B1 (en) 1998-01-28 2001-04-03 The Universite Laval Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities
WO1999041613A1 (en) 1998-02-12 1999-08-19 Immunivest Methods and reagents for the rapid and efficient isolation of circulating cancer cells
US20010018192A1 (en) 1998-02-12 2001-08-30 Terstappen Leon W.M.M. Labeled cells for use as an internal functional control in rare cell detection assays
US6177163B1 (en) 1998-06-22 2001-01-23 Tricor Direct, Inc. Markable repositionable adhesive sheet dispensing roll for use in an industrial setting
AU740441B2 (en) 1998-06-30 2001-11-01 La Mina Ltd Cytological and histological fixative composition and methods of use
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US20080261292A1 (en) 1998-09-22 2008-10-23 Oncomedx, Inc. Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions
US7683035B1 (en) 1999-02-23 2010-03-23 Qiagen, Gmbh Method of stabilizing and/or isolating nucleic acids
US6077235A (en) 1999-02-23 2000-06-20 Becton, Dickinson And Company Blood collection assembly and method therefor
WO2000075647A1 (en) 1999-06-04 2000-12-14 Bioseparations, Inc. System and method for prenatal diagnostic screening
WO2000077235A1 (en) 1999-06-16 2000-12-21 University Of Cincinnati Agent and process for isolation of extra-chromosomal nucleic acids
DE19928820A1 (de) 1999-06-17 2000-12-21 Ulrich Groth Fixiermittel für Zellen und Gewebe von Lebewesen
AU6498600A (en) 1999-07-29 2001-02-19 Baxter International Inc. Sampling tube holder for blood sampling system
US6221668B1 (en) 1999-08-20 2001-04-24 Streck Laboratories, Inc. Hematology control and system for multi-parameter hematology measurements
US6200500B1 (en) 1999-08-20 2001-03-13 Streck Laboratories, Inc. Hematology control and system for multi-parameter hematology measurements
WO2001021830A1 (en) 1999-09-24 2001-03-29 Ambion, Inc. Nuclease inhibitor cocktail
US20010049895A1 (en) 2000-01-06 2001-12-13 Burke Doyle G. Promotional hanger
US6337189B1 (en) 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
DE10006662A1 (de) 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
GB0009179D0 (en) 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
US7129326B2 (en) 2000-04-14 2006-10-31 Genencor International, Inc. Methods for selective targeting
GB0009784D0 (en) 2000-04-20 2000-06-07 Simeg Limited Methods for clinical diagnosis
US20020045196A1 (en) 2000-05-12 2002-04-18 Walt Mahoney Methods of isolating trophoblast cells from maternal blood
AU2001265396A1 (en) 2000-06-08 2001-12-17 Stacy R. Kaufman Verification of prescription information and warning label
AU1548802A (en) 2000-06-21 2002-01-02 Digene Corp Universal collection medium
DE60131986T2 (de) 2000-08-10 2008-08-28 Baxa Corp., Englewood Artikel zum handhaben, etikettieren, füllen und verschliessen von spritzen
US6664056B2 (en) 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring
WO2002033129A2 (en) 2000-10-17 2002-04-25 Impath, Inc. Nucleic acid amplification controls
US6551267B1 (en) 2000-10-18 2003-04-22 Becton, Dickinson And Company Medical article having blood-contacting surface
GB0026459D0 (en) 2000-10-28 2000-12-13 Imp College Innovations Ltd Screening assays
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
EP1356302B1 (en) 2000-11-08 2008-01-23 Becton Dickinson and Company Method and device for collecting and stabilizing a biological sample
CA2428757A1 (en) 2000-11-15 2002-07-18 Roche Diagnostics Corporation Methods and reagents for identifying rare fetal cells in the maternal circulation
US7029840B2 (en) 2000-11-15 2006-04-18 Becton, Dickinson And Company Method for preservation of cells and nucleic acid targets
EP1207208A3 (en) 2000-11-15 2003-12-10 Becton Dickinson and Company Method for preservation of cells and nucleic acid targets
US20020066216A1 (en) 2000-12-01 2002-06-06 Delacruz Cedric G. Baby birth announcement
US6794152B2 (en) 2000-12-22 2004-09-21 Streck Laboratories Inc. Flow cytometry reagent and system
JP4453999B2 (ja) 2001-02-14 2010-04-21 栄研化学株式会社 尿中蛋白及びペプチドの安定化方法
US6581973B2 (en) 2001-03-30 2003-06-24 Cheringal Associates, Inc. Double blind study label
US6617180B1 (en) 2001-04-16 2003-09-09 Taiwan Semiconductor Manufacturing Company Test structure for detecting bridging of DRAM capacitors
FR2824144B1 (fr) 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
ES2367280T3 (es) 2001-07-25 2011-11-02 Oncomedx Inc. Métodos para evaluar estados patológicos usando arn extracelular.
WO2008111981A1 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation of macromolecules
US7863012B2 (en) 2004-02-17 2011-01-04 Veridex, Llc Analysis of circulating tumor cells, fragments, and debris
WO2003019141A2 (en) 2001-08-23 2003-03-06 Immunivest Corporation Analysis of circulating tumor cells, fragments, and debris
WO2003020116A2 (en) 2001-08-31 2003-03-13 University Of North Carolina At Chapel Hill Fixed-dried red blood cells
US6527242B1 (en) 2001-10-01 2003-03-04 Netta Kennedy Brace for a picture frame
IL161357A0 (en) 2001-10-26 2004-09-27 Immunivest Corp Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
ATE357138T1 (de) * 2001-11-21 2007-04-15 Altachem Pharma Ltd Antipathogenische zusammensetzung verwendbar in der konservierung von blut
US6994790B2 (en) 2002-02-01 2006-02-07 Gambro, Inc. Whole blood collection and processing method
GB0203280D0 (en) 2002-02-12 2002-03-27 Ic Innovations Ltd Anti-glycolytic composition
WO2003070283A2 (en) 2002-02-22 2003-08-28 Klaus Strebhardt Agent for inhibiting development or progress of proliferative diseases and especially cancer diseases and pharmaceutical composition containing said agent
GB2386038A (en) 2002-02-27 2003-09-03 Motorola Inc Channel estimation in a radio receiver
BR0308161A (pt) 2002-03-01 2006-06-06 Ravgen Inc métodos para a detecção de distúrbios genéticos
US6977162B2 (en) 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
DK1342794T3 (da) 2002-03-05 2006-04-24 Epigenomics Ag Fremgangsmåde og anordning til at bestemme vævsspecificitet af fritflydende DNA i legemsvæsker
US20040043505A1 (en) 2002-05-07 2004-03-04 Matthew Walenciak Collection assembly
US7727720B2 (en) 2002-05-08 2010-06-01 Ravgen, Inc. Methods for detection of genetic disorders
US20070178478A1 (en) 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US7442506B2 (en) 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
EP1501565B1 (de) 2002-05-09 2006-11-02 Hemoteq GmbH Verbindungen und verfahren zur hemokompatiblen beschichtung von oberflächen
US7022478B2 (en) 2002-05-14 2006-04-04 The Chinese University Of Hong Kong Methods for evaluating stroke or cardiac ischemia by nucleic acid detection
AU2003239543A1 (en) 2002-05-22 2003-12-12 Duke University Rnp immunoprecipitation assay
JP2003344389A (ja) 2002-05-29 2003-12-03 Sysmex Corp 抗凝固剤
AU2003243475A1 (en) 2002-06-13 2003-12-31 New York University Early noninvasive prenatal test for aneuploidies and heritable conditions
US20060008807A1 (en) 2002-08-23 2006-01-12 O'hara Shawn M Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
US6913932B2 (en) 2002-08-23 2005-07-05 Beckman Coulter, Inc. Formaldehyde-ammonium salt complexes for the stabilization of blood cells
EP1816461B1 (en) 2002-10-16 2020-01-08 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
KR100471183B1 (ko) 2002-10-29 2005-03-10 삼성전자주식회사 오프 세트 트랜지스터를 갖는 반도체 기억소자 및 그제조방법
EP1599608A4 (en) 2003-03-05 2007-07-18 Genetic Technologies Ltd Identification of fetal DNA and fetal cell marker in maternal plasma or serum
US7267980B1 (en) 2003-04-04 2007-09-11 Research & Diagnostic Systems, Inc. Stabilizing solution for cells and tissues
US20050277204A1 (en) 2003-08-12 2005-12-15 Massachusetts Institute Of Technology Sample preparation methods and devices
US7318293B2 (en) 2003-09-19 2008-01-15 Ardern Ii William B Binder clip sleeve
DE60328193D1 (de) 2003-10-16 2009-08-13 Sequenom Inc Nicht invasiver Nachweis fötaler genetischer Merkmale
BRPI0415850A (pt) * 2003-10-23 2007-01-02 Alza Corp composição de dna estabilizado para o revestimento de micro projeções
US20070111233A1 (en) 2003-10-30 2007-05-17 Bianchi Diana W Prenatal diagnosis using cell-free fetal DNA in amniotic fluid
US20050181353A1 (en) 2004-02-17 2005-08-18 Rao Galla C. Stabilization of cells and biological specimens for analysis
US20100216153A1 (en) 2004-02-27 2010-08-26 Helicos Biosciences Corporation Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities
US20080119645A1 (en) 2004-05-05 2008-05-22 Isis Pharmaceuticals, Inc. Amidites and Methods of Rna Synthesis
US8497134B2 (en) 2004-08-19 2013-07-30 Blood Cell Storage, Inc. Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices
ES2251307B2 (es) 2004-10-05 2006-12-16 Universidad Complutense De Madrid Solucion para el mantenimiento indefinido de los acidos nucleicos en su celula de origen.
US20060105372A1 (en) 2004-11-05 2006-05-18 Bair Robert J Compositions and methods for purifying nucleic acids from stabilization reagents
US20090215036A1 (en) 2004-12-10 2009-08-27 Bayer Healthcare Ag Genetic Alterations Useful For The Response Prediction of Malignant Neoplasia to Taxane-Based Medical Treatments
US7390663B2 (en) 2005-02-23 2008-06-24 Streck, Inc. Process, composition and kit for providing a stable whole blood calibrator/control
US7419832B2 (en) 2005-03-10 2008-09-02 Streck, Inc. Blood collection tube with surfactant
DE102005013261A1 (de) 2005-03-22 2006-09-28 Adnagen Ag Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen
US20080280290A1 (en) 2005-08-19 2008-11-13 Dawson Elliott P Method and Device for the Collection and Isolation of Nucleic Acid
WO2007053491A2 (en) 2005-10-28 2007-05-10 The Trustees Of Columbia University In The City Of New York Method and kit for evaluating rna quality
WO2007092473A2 (en) 2006-02-02 2007-08-16 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive fetal genetic screening by digital analysis
SI1996728T1 (sl) 2006-02-28 2011-10-28 Univ Louisville Res Found Prepoznavanje kromosomskih nenormalnosti pri zarodku s pomočjo dvojnih mononukleotidnih polimorfizmov
JP2009528059A (ja) 2006-02-28 2009-08-06 メタボロン インコーポレイテッド 筋萎縮性側索硬化症に関するバイオマーカー及びそれらを使用する方法
US20070243548A1 (en) 2006-03-28 2007-10-18 Elias Georges Calumenin-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance
WO2007121276A2 (en) 2006-04-12 2007-10-25 Biocept, Inc. Enrichment of circulating fetal dna
ES2264403B1 (es) 2006-06-22 2007-11-01 Grifols S.A. Medio de suspension de hematies.
WO2008006086A2 (en) 2006-07-07 2008-01-10 Atlantic City Coin & Slot Service Company, Inc. Gaming device and method of use
CN101528763B (zh) 2006-08-30 2012-06-27 生物风险公司 分离和检测小多核苷酸的方法和物质
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US20080108071A1 (en) 2006-10-10 2008-05-08 Katherine Thompson Methods and Systems to Determine Fetal Sex and Detect Fetal Abnormalities
US9316633B2 (en) 2006-11-16 2016-04-19 The Regents Of The University Of California Methods for identifying inhibitors of solute transporters
GB0704488D0 (en) 2007-03-08 2007-04-18 Univ Nottingham Platelet viability kit
US20090011043A1 (en) 2007-07-03 2009-01-08 Hua Xie Tissue sealant made from whole blood
US8537789B2 (en) 2007-08-01 2013-09-17 Harris Corporation Mobile ad-hoc network providing communication latency reduction features and related methods
CN101148658A (zh) 2007-09-06 2008-03-26 四川省食品发酵工业研究设计院 动物血双水相提取超氧化物歧化酶方法
WO2009042457A1 (en) 2007-09-21 2009-04-02 Streck, Inc. Nucleic acid isolation in preserved whole blood
US20090197275A1 (en) 2008-02-06 2009-08-06 Acrometrix Corporation Controls For Detecting Methicillin Resistant Staphylococcus Aureus (MRSA)
WO2009105499A1 (en) 2008-02-20 2009-08-27 Termaat Joel R Thermocycler and sample vessel for rapid amplification of dna
US20090308303A1 (en) 2008-06-13 2009-12-17 Burlando Albert A Identification marker
PE20141398A1 (es) 2008-07-16 2014-10-18 Inst Research In Biomedicine Anticuerpos neutralizantes de citomegalovirus humano
US20100167271A1 (en) 2008-12-30 2010-07-01 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
AU2010209763B2 (en) 2009-01-30 2016-05-12 Mycartis N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
US8304187B2 (en) 2009-02-18 2012-11-06 Streck, Inc. Preservation of cell-free RNA in blood samples
JP5923035B2 (ja) 2009-03-24 2016-05-24 バイオセプト インコーポレイティッド 細胞の捕捉および解析のデバイスおよび方法
WO2010132756A2 (en) 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
US8715920B2 (en) 2010-07-27 2014-05-06 Biovec Transfusion, Llc Composition for preserving platelets during photosensitization
WO2011014741A1 (en) 2009-07-31 2011-02-03 Artemis Health, Inc. Methods and compositions for cell stabilization
US20110053208A1 (en) 2009-08-31 2011-03-03 Streck, Inc. Biological sample identification system
US20110110975A1 (en) 2009-11-06 2011-05-12 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
US20110111410A1 (en) 2009-11-09 2011-05-12 Streck, Inc. Stabilization of rna in intact cells within a blood sample
US8722328B2 (en) 2010-01-04 2014-05-13 Qiagen Gaithersburg, Inc. Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples
US8900864B2 (en) 2010-09-21 2014-12-02 Nordrhein-Wesfalen Krankenhausbetriebsgesellschaft Bad Oeynhausen mbH Stabilized leukocytes and their use
WO2012040603A2 (en) 2010-09-23 2012-03-29 Biocept, Inc. Use of diazolidinyl urea for anti-clumping of biological samples
US8546144B2 (en) 2010-11-17 2013-10-01 Streck, Inc. Method of preparing controls for glycated hemoglobin S-A1c derived from healthy blood cells
US8551784B2 (en) 2010-11-17 2013-10-08 Streck, Inc. Cis di-ahl modified controls for glycated hemoglobin S-A1c derived from healthy blood cells
US8889086B2 (en) 2011-04-21 2014-11-18 Streck, Inc. Sample tube having particular utility for nucleic acid amplification
US20120308985A1 (en) 2011-04-21 2012-12-06 Streck, Inc. Immature Reticulocyte Fraction Reference Control and Related Methods
EP2704740B1 (en) 2011-05-04 2016-10-05 Streck, Inc. Inactivated swine flu virus and methods of preparing it
CA2835654A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
CA2858689A1 (en) 2011-12-09 2013-06-13 The Scripps Research Institute Apparatus, system and method for identifying circulating tumor cells
CA2862544A1 (en) 2012-02-02 2013-08-08 Randal Alan Hoke Sample collection devices with blood stabilizing agents
EP3225699B1 (en) 2012-02-13 2020-09-30 Streck, Inc. Blood collection device for improved nucleic acid regulation
JP5889220B2 (ja) 2012-03-30 2016-03-22 富士フイルム株式会社 水性分散組成物
EP2888363B1 (en) 2012-08-21 2018-06-06 Qiagen GmbH Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
JP6608280B2 (ja) 2012-09-25 2019-11-20 キアゲン ゲーエムベーハー 生物学的試料の安定化
US20140199681A1 (en) 2013-01-14 2014-07-17 Streck, Inc. Blood collection device for stabilizing cell-free rna in blood during sample shipping and storage
WO2014145078A1 (en) 2013-03-15 2014-09-18 Verinata Health, Inc. Generating cell-free dna libraries directly from blood
WO2014210593A1 (en) 2013-06-28 2014-12-31 Streck, Inc. Devices for real-time polymerase chain reaction
US20150030578A1 (en) 2013-07-23 2015-01-29 Bill J. Releford, JR. Method for producing activated autologous platelet rich and platelet poor plasma and methods of use
EP3024323B1 (en) 2013-07-24 2022-10-19 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
AU2014385192A1 (en) 2014-03-04 2016-09-22 Streck, Inc. Improved sample tube with transparent tip having particular utility for nucleic acid amplification
JP6302772B2 (ja) 2014-06-30 2018-03-28 日立建機株式会社 建設機械の油圧システム
CN104070871B (zh) 2014-07-05 2016-08-24 安徽索亚装饰材料有限公司 一种无磷润版液及其制备方法
CN104381245B (zh) 2014-10-13 2016-05-11 广东佛山国盛医学科技有限公司 一种稳定血液样品细胞的试剂
CN104634628B (zh) 2014-12-16 2017-03-29 广东腾飞基因科技有限公司 一种血液稳定剂及其应用
CN105985904A (zh) 2015-02-26 2016-10-05 付士明 循环游离dna真空采集管
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
JP6382156B2 (ja) * 2015-06-08 2018-08-29 パラマウントベッド株式会社 ケーブル用支持具
US20170097361A1 (en) 2015-07-15 2017-04-06 Streck, Inc. Method and device for stabilizing of proteins
CN108138316A (zh) 2015-08-18 2018-06-08 Sio2医药产品公司 具有低氧气传输速率的药物和其他包装
US20170052173A1 (en) 2015-08-19 2017-02-23 Streck, Inc. Sperm count quality controls
JP6617495B2 (ja) 2015-09-18 2019-12-11 東ソー株式会社 腫瘍細胞の検出方法
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
AU2017269608C1 (en) 2016-05-27 2023-12-07 Norgen Biotek Corp. Preservation of cell-free nucleic acids in biological samples
CA3024996A1 (en) 2016-06-08 2017-12-14 Cf Genome, Llc A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof
WO2017218789A1 (en) 2016-06-15 2017-12-21 Streck, Inc. Assays and methods for determining microbial resistance
EP3491381B1 (en) 2016-07-29 2025-09-24 Streck LLC Suspension composition for hematology analysis control
WO2018031903A1 (en) 2016-08-12 2018-02-15 Streck, Inc. Molecular reference controls
EP3845665A1 (en) 2016-08-17 2021-07-07 The Regents Of The University Of California A novel immunoprobe-based method to assess organ injury status through a biofluid-based cell-free dna (cfdna) assay
CN106244535B (zh) * 2016-08-30 2019-09-20 成都瑞琦科技实业股份有限公司 孕妇外周血中胎儿游离dna的保存剂及其构成的真空采血管
WO2018145005A1 (en) 2017-02-03 2018-08-09 Streck, Inc. Sample collection tube with preservative
CN106872338A (zh) * 2017-02-28 2017-06-20 珠海丽珠圣美医疗诊断技术有限公司 一种血液细胞稳定剂及其应用
CN106900692A (zh) * 2017-03-06 2017-06-30 上海迅伯生物科技有限公司 一种血液dna的保存剂组合物
WO2019025387A1 (de) 2017-08-02 2019-02-07 Sarstedt Ag & Co. Kg Verfahren und zusammensetzung zur stabilisierung zellfreier nukleinsäuren und zellen
CN107525818A (zh) 2017-09-29 2017-12-29 上海华盈生物医药科技有限公司 一种从尿液中提取外泌体的方法及试剂
JP7293244B2 (ja) 2017-10-19 2023-06-19 ストレック, インコーポレイテッド 溶血、凝固調節および細胞外小胞の安定化のための組成物
WO2019090126A1 (en) 2017-11-03 2019-05-09 Streck, Inc. Linearity control materials
WO2019147824A1 (en) 2018-01-26 2019-08-01 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor
WO2020140035A1 (en) 2018-12-27 2020-07-02 Streck, Inc. Methods of preparing samples for proteomic analysis

Also Published As

Publication number Publication date
EP3697209A4 (en) 2021-07-28
WO2019079743A8 (en) 2019-09-19
JP7293244B2 (ja) 2023-06-19
EP4427588A2 (en) 2024-09-11
CN115119829A (zh) 2022-09-30
JP2023116615A (ja) 2023-08-22
EP4427588A3 (en) 2024-10-16
EP3697209B1 (en) 2024-07-24
US20210371848A1 (en) 2021-12-02
CA3079415A1 (en) 2019-04-25
CN111372451A (zh) 2020-07-03
ES2991437T3 (es) 2024-12-03
WO2019079743A1 (en) 2019-04-25
EP3697209A1 (en) 2020-08-26
JP7606566B2 (ja) 2024-12-25
JP2021500585A (ja) 2021-01-07
US12378543B2 (en) 2025-08-05
HUE068517T2 (hu) 2024-12-28
CN115119829B (zh) 2024-07-12
CN111372451B (zh) 2022-08-12

Similar Documents

Publication Publication Date Title
HUE068517T2 (hu) A hemolízis és a véralvadás szabályozására, valamint az extracelluláris vezikulák stabilizálására szolgáló készítmények
IL268999A (en) Compounds and preparations for intracellular administration of medicinal agents
PT3350157T (pt) Compostos e composições para administração intracelular de agentes terapêuticos
SMT202200252T1 (it) Composti e composizioni per il rilascio intracellulare di agenti
SI3386484T1 (sl) Sestave in metode za dovajanje terapevtskih sredstev
IL258584A (en) Spoilage inhibiting preparations for crop treatment
EP3673899C0 (en) NASAL POWDER FORMULATION FOR THE TREATMENT OF HYPOGLYCEMIA
IL258032A (en) Compounds and preparations for the treatment of ocular disorders
SI3102555T1 (sl) Sestavki spojin in njihove uporabe
EP3271015B8 (en) Nk-3 receptor antagonists for therapeutic or cosmetic treatment of excess body fat
SG11202011723XA (en) Stabilization of collagen scaffolds
GB2574740B (en) Characterisation of emulsion stability
IL282504A (en) Ocular formulations for drug administration and protection of the front part of the eye
PL3277287T3 (pl) Mieszaniny oligosacharydów mleka ludzkiego zawierające 3'-O-sialilolaktozę
PL3544420T3 (pl) Zastosowanie kompozycji do konserwowania narządów/tkanek
ZA201800175B (en) Methods and compositions for selective regulation of protein expression
EP3334388A4 (en) INTERSPINAL STABILIZATION IMPLANT
PL3185891T3 (pl) Rekombinowane białka fuzyjne do zapobiegania lub leczenia adhezji w tkankach lub narządach
AU2015900728A0 (en) Therapeutic extracellular vesicles and methods of use thereof
HUP1400494A2 (en) Stabilizing strip of improved properties for treating bone fractures
GB201405162D0 (en) Theory of cosmetic surgeries, procedures and enhancements
GB201413543D0 (en) The Game of 'Tum Tac Toe'