PL369999A1 - Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzoazepiny lub jej sól - Google Patents
Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzoazepiny lub jej sólInfo
- Publication number
- PL369999A1 PL369999A1 PL02369999A PL36999902A PL369999A1 PL 369999 A1 PL369999 A1 PL 369999A1 PL 02369999 A PL02369999 A PL 02369999A PL 36999902 A PL36999902 A PL 36999902A PL 369999 A1 PL369999 A1 PL 369999A1
- Authority
- PL
- Poland
- Prior art keywords
- difluoro
- tetrahydro
- salts
- benzazepine derivatives
- benzazepine
- Prior art date
Links
- DTSDJGNXLLPHFA-UHFFFAOYSA-N 4,4-difluoro-1,2,3,5-tetrahydro-1-benzazepine Chemical class C1C(F)(F)CCNC2=CC=CC=C21 DTSDJGNXLLPHFA-UHFFFAOYSA-N 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title 1
- 101800001144 Arg-vasopressin Proteins 0.000 abstract 1
- 208000003450 Neurogenic Diabetes Insipidus Diseases 0.000 abstract 1
- 102100026383 Vasopressin-neurophysin 2-copeptin Human genes 0.000 abstract 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 abstract 1
- 208000028235 central diabetes insipidus Diseases 0.000 abstract 1
- 201000010064 diabetes insipidus Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 201000005119 neurohypophyseal diabetes insipidus Diseases 0.000 abstract 1
- 206010029446 nocturia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001350909 | 2001-11-16 | ||
| JP2002252931 | 2002-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL369999A1 true PL369999A1 (pl) | 2005-05-16 |
Family
ID=26624548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02369999A PL369999A1 (pl) | 2001-11-16 | 2002-11-13 | Pochodna 4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzoazepiny lub jej sól |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7169772B2 (pl) |
| EP (1) | EP1445253B1 (pl) |
| JP (1) | JP4075064B2 (pl) |
| KR (1) | KR100632882B1 (pl) |
| CN (1) | CN1323076C (pl) |
| AT (1) | ATE438626T1 (pl) |
| AU (1) | AU2002349773B2 (pl) |
| BR (1) | BR0214224A (pl) |
| CA (1) | CA2464069A1 (pl) |
| DE (1) | DE60233251D1 (pl) |
| ES (1) | ES2327620T3 (pl) |
| HU (1) | HUP0402235A2 (pl) |
| MX (1) | MXPA04004501A (pl) |
| NO (1) | NO20042497L (pl) |
| PL (1) | PL369999A1 (pl) |
| RU (1) | RU2268882C1 (pl) |
| WO (1) | WO2003042181A1 (pl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| CA2497560A1 (en) | 2002-09-20 | 2004-04-01 | Promega Corporation | Luminescence-based methods and probes for measuring cytochrome p450 activity |
| WO2004047730A2 (en) * | 2002-11-21 | 2004-06-10 | New York Blood Center | Compounds for inhibition of hiv infection by blocking hiv entry |
| ATE512951T1 (de) | 2003-04-28 | 2011-07-15 | Astellas Pharma Inc | 4,4-difluor-1,2,3,4-tetrahydro-5h-1- benzazepinderivat oder salz davon |
| WO2005090282A1 (en) | 2004-03-12 | 2005-09-29 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| EP1885875B1 (en) | 2005-05-31 | 2019-05-22 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| EP1935986B1 (en) | 2005-05-31 | 2014-04-16 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| KR101136183B1 (ko) | 2005-07-22 | 2012-04-17 | 모찌다 세이야쿠 가부시끼가이샤 | 신규 헤테로시클리덴 아세트아미드 유도체 |
| JP5164510B2 (ja) * | 2006-10-06 | 2013-03-21 | 日本曹達株式会社 | 含窒素複素環化合物および有害生物防除剤 |
| JPWO2008078725A1 (ja) | 2006-12-26 | 2010-04-30 | 第一三共株式会社 | チアゼピン誘導体 |
| PE20081692A1 (es) | 2007-01-24 | 2008-12-18 | Mochida Pharm Co Ltd | Nuevo derivado de heterocicliden acetamida |
| US20100016285A1 (en) * | 2007-01-24 | 2010-01-21 | Mochida Pharmaceutical Co., Ltd. | Heterocyclidene-n-(aryl) acetamide derivative |
| EP2133331A4 (en) | 2007-04-11 | 2011-06-22 | Kissei Pharmaceutical | FIVE-GLASS HETEROCYCLIC DERIVATIVE AND ITS USE IN MEDICAL PURPOSES |
| KR20140143461A (ko) | 2007-08-06 | 2014-12-16 | 알레간 인코포레이티드 | 데스모프레신 약물 전달을 위한 방법 및 장치 |
| US20100286045A1 (en) | 2008-05-21 | 2010-11-11 | Bjarke Mirner Klein | Methods comprising desmopressin |
| US11963995B2 (en) | 2008-05-21 | 2024-04-23 | Ferring B.V. | Methods comprising desmopressin |
| ES2756706T3 (es) * | 2008-05-21 | 2020-04-27 | Ferring Bv | Desmopresina bucodispersable para aumentar el periodo inicial de sueño ininterrumpido por nocturia |
| UY32940A (es) | 2009-10-27 | 2011-05-31 | Bayer Cropscience Ag | Amidas sustituidas con halogenoalquilo como insecticidas y acaricidas |
| NO2860175T3 (pl) | 2012-06-11 | 2018-04-28 | ||
| MX362478B (es) * | 2012-12-26 | 2019-01-11 | Sanwa Kagaku Kenkyusho Co | Derivado de benzoazepina novedoso y uso medico del mismo. |
| EP3099683B1 (en) | 2014-01-29 | 2020-08-05 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| CN105310978A (zh) * | 2014-08-04 | 2016-02-10 | 李峰 | 一种含有活性成分盐酸考尼伐坦的药物组合物及其制剂 |
| MX2021012690A (es) | 2019-04-19 | 2022-01-31 | Ligand Pharm Inc | Formas cristalinas y metodos para producir formas cristalinas de un compuesto. |
| CN112079826B (zh) * | 2020-09-17 | 2022-07-29 | 广州中医药大学(广州中医药研究院) | 一类甾体合成酶抑制剂及其治疗应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1039999A (zh) * | 1988-07-30 | 1990-02-28 | 刘晓非 | 多层复合装饰板及制作方法 |
| TW270927B (pl) | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| HUT73526A (en) * | 1993-08-26 | 1996-08-28 | Yamanouchi Pharma Co Ltd | Benzazepine derivative, pharmaceutical composition containing the same, and intermediate for the same |
| TW359669B (en) * | 1995-12-15 | 1999-06-01 | Otsuka Pharma Co Ltd | Benzazepine derivatives |
| JPH09221475A (ja) * | 1996-02-13 | 1997-08-26 | Yamanouchi Pharmaceut Co Ltd | 新規なオキシム誘導体 |
| AR011913A1 (es) | 1997-03-06 | 2000-09-13 | Yamano Masaki | Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos. |
-
2002
- 2002-11-13 MX MXPA04004501A patent/MXPA04004501A/es active IP Right Grant
- 2002-11-13 PL PL02369999A patent/PL369999A1/pl not_active Application Discontinuation
- 2002-11-13 US US10/495,494 patent/US7169772B2/en not_active Expired - Fee Related
- 2002-11-13 DE DE60233251T patent/DE60233251D1/de not_active Expired - Lifetime
- 2002-11-13 KR KR1020047007126A patent/KR100632882B1/ko not_active Expired - Fee Related
- 2002-11-13 EP EP02781759A patent/EP1445253B1/en not_active Expired - Lifetime
- 2002-11-13 AT AT02781759T patent/ATE438626T1/de not_active IP Right Cessation
- 2002-11-13 WO PCT/JP2002/011842 patent/WO2003042181A1/ja not_active Ceased
- 2002-11-13 RU RU2004118063/04A patent/RU2268882C1/ru not_active IP Right Cessation
- 2002-11-13 JP JP2003544017A patent/JP4075064B2/ja not_active Expired - Fee Related
- 2002-11-13 BR BR0214224-4A patent/BR0214224A/pt not_active IP Right Cessation
- 2002-11-13 CA CA002464069A patent/CA2464069A1/en not_active Abandoned
- 2002-11-13 HU HU0402235A patent/HUP0402235A2/hu unknown
- 2002-11-13 CN CNB028226046A patent/CN1323076C/zh not_active Expired - Fee Related
- 2002-11-13 AU AU2002349773A patent/AU2002349773B2/en not_active Ceased
- 2002-11-13 ES ES02781759T patent/ES2327620T3/es not_active Expired - Lifetime
-
2004
- 2004-06-15 NO NO20042497A patent/NO20042497L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1445253A4 (en) | 2005-11-16 |
| JP4075064B2 (ja) | 2008-04-16 |
| WO2003042181A1 (en) | 2003-05-22 |
| US7169772B2 (en) | 2007-01-30 |
| US20050004103A1 (en) | 2005-01-06 |
| RU2268882C1 (ru) | 2006-01-27 |
| ATE438626T1 (de) | 2009-08-15 |
| RU2004118063A (ru) | 2006-01-10 |
| KR100632882B1 (ko) | 2006-10-13 |
| EP1445253B1 (en) | 2009-08-05 |
| ES2327620T3 (es) | 2009-11-02 |
| CN1323076C (zh) | 2007-06-27 |
| BR0214224A (pt) | 2004-09-21 |
| CA2464069A1 (en) | 2003-05-22 |
| MXPA04004501A (es) | 2004-08-11 |
| DE60233251D1 (de) | 2009-09-17 |
| EP1445253A1 (en) | 2004-08-11 |
| KR20050044401A (ko) | 2005-05-12 |
| AU2002349773B2 (en) | 2007-12-13 |
| HUP0402235A2 (hu) | 2005-02-28 |
| NO20042497L (no) | 2004-07-21 |
| JPWO2003042181A1 (ja) | 2005-03-10 |
| CN1585752A (zh) | 2005-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |