PL370029A1 - Pochodne 2-amino-4-heteroaryloaminopirymidyny do stosowania w leczeniu raka - Google Patents
Pochodne 2-amino-4-heteroaryloaminopirymidyny do stosowania w leczeniu rakaInfo
- Publication number
- PL370029A1 PL370029A1 PL02370029A PL37002902A PL370029A1 PL 370029 A1 PL370029 A1 PL 370029A1 PL 02370029 A PL02370029 A PL 02370029A PL 37002902 A PL37002902 A PL 37002902A PL 370029 A1 PL370029 A1 PL 370029A1
- Authority
- PL
- Poland
- Prior art keywords
- heteroarylaminopyrimidine
- cancer
- derivatives
- amino
- treatment
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31428501P | 2001-08-22 | 2001-08-22 | |
| US10/225,819 US7115617B2 (en) | 2001-08-22 | 2002-08-21 | Amino-substituted pyrimidinyl derivatives and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL370029A1 true PL370029A1 (pl) | 2005-05-16 |
Family
ID=26919947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02370029A PL370029A1 (pl) | 2001-08-22 | 2002-08-22 | Pochodne 2-amino-4-heteroaryloaminopirymidyny do stosowania w leczeniu raka |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7115617B2 (pl) |
| EP (1) | EP1418916A1 (pl) |
| JP (1) | JP2005501860A (pl) |
| AU (1) | AU2002329826C1 (pl) |
| CA (1) | CA2458011A1 (pl) |
| MX (1) | MXPA04001622A (pl) |
| PL (1) | PL370029A1 (pl) |
| WO (1) | WO2003018022A1 (pl) |
Families Citing this family (82)
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| US20050075358A1 (en) * | 2003-10-06 | 2005-04-07 | Carboni Joan M. | Methods for treating IGF1R-inhibitor induced hyperglycemia |
| UA83509C2 (en) * | 2003-10-15 | 2008-07-25 | Оси Фармасьютикалз, Инк. | Imidazopyrazines as tyrosine kinase inhibitors |
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| CN107903256B (zh) * | 2017-11-29 | 2019-11-15 | 南方医科大学 | 一种含取代噻唑的2,4-二氨基嘧啶及其应用 |
| CN112469414A (zh) * | 2018-05-25 | 2021-03-09 | 昂科库博疗法有限责任公司 | 作为新型候选抗癌药物的高效力tacc3抑制剂 |
| EP3810132A4 (en) | 2018-06-25 | 2022-06-22 | Dana-Farber Cancer Institute, Inc. | TAIRE FAMILY KINASE INHIBITORS AND RELATED USES |
| US12281126B2 (en) | 2018-12-28 | 2025-04-22 | Dana-Farber Cancer Institute, Inc. | Inhibitors of cyclin-dependent kinase 7 and uses thereof |
| CN115279754A (zh) * | 2019-11-14 | 2022-11-01 | A2A制药有限公司 | 靶向tacc3的异恶唑衍生物作为抗癌剂 |
| KR102472103B1 (ko) * | 2019-12-03 | 2022-11-29 | 삼진제약주식회사 | 국소 부착 키나아제 저해제로서 신규한 아다만탄 유도체 |
| CN111518078B (zh) * | 2020-05-30 | 2021-02-26 | 南方医科大学 | 一种含氨基吡啶的嘧啶类化合物及其应用 |
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-
2002
- 2002-08-21 US US10/225,819 patent/US7115617B2/en not_active Expired - Fee Related
- 2002-08-22 PL PL02370029A patent/PL370029A1/pl not_active Application Discontinuation
- 2002-08-22 MX MXPA04001622A patent/MXPA04001622A/es active IP Right Grant
- 2002-08-22 CA CA002458011A patent/CA2458011A1/en not_active Abandoned
- 2002-08-22 JP JP2003522540A patent/JP2005501860A/ja active Pending
- 2002-08-22 EP EP02766079A patent/EP1418916A1/en not_active Withdrawn
- 2002-08-22 WO PCT/US2002/026926 patent/WO2003018022A1/en not_active Ceased
- 2002-08-22 AU AU2002329826A patent/AU2002329826C1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005501860A (ja) | 2005-01-20 |
| WO2003018022A1 (en) | 2003-03-06 |
| MXPA04001622A (es) | 2004-07-08 |
| US7115617B2 (en) | 2006-10-03 |
| EP1418916A1 (en) | 2004-05-19 |
| AU2002329826B2 (en) | 2005-06-09 |
| US20030125346A1 (en) | 2003-07-03 |
| AU2002329826C1 (en) | 2005-11-17 |
| CA2458011A1 (en) | 2003-03-06 |
| WO2003018022A8 (en) | 2003-10-02 |
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| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |