PL370426A1 - Wytłaczanie stopionych soli zawierających składniki czynne - Google Patents
Wytłaczanie stopionych soli zawierających składniki czynneInfo
- Publication number
- PL370426A1 PL370426A1 PL03370426A PL37042603A PL370426A1 PL 370426 A1 PL370426 A1 PL 370426A1 PL 03370426 A PL03370426 A PL 03370426A PL 37042603 A PL37042603 A PL 37042603A PL 370426 A1 PL370426 A1 PL 370426A1
- Authority
- PL
- Poland
- Prior art keywords
- active ingredient
- salts
- granule
- meth
- active ingredients
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000001125 extrusion Methods 0.000 title 1
- 239000008187 granular material Substances 0.000 abstract 3
- 239000000843 powder Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
- Seasonings (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10208344A DE10208344A1 (de) | 2002-02-27 | 2002-02-27 | Schmelzextrusion von Wirkstoffsalzen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL370426A1 true PL370426A1 (pl) | 2005-05-30 |
| PL204465B1 PL204465B1 (pl) | 2010-01-29 |
Family
ID=27675020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL370426A PL204465B1 (pl) | 2002-02-27 | 2003-01-30 | Sposób wytwarzania granulatów lub proszków zawierających substancje czynne, granulaty lub proszek wytwarzane tym sposobem oraz zastosowanie tych granulatów lub proszków |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8642089B2 (pl) |
| EP (1) | EP1478344B1 (pl) |
| JP (1) | JP5054278B2 (pl) |
| KR (1) | KR100707712B1 (pl) |
| AT (1) | ATE362754T1 (pl) |
| AU (1) | AU2003210196A1 (pl) |
| BR (1) | BRPI0307995B8 (pl) |
| CA (1) | CA2474691C (pl) |
| DE (2) | DE10208344A1 (pl) |
| ES (1) | ES2286447T3 (pl) |
| IL (2) | IL162082A0 (pl) |
| MX (1) | MXPA04008345A (pl) |
| PL (1) | PL204465B1 (pl) |
| WO (1) | WO2003072083A2 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10239999A1 (de) * | 2002-08-27 | 2004-03-04 | Röhm GmbH & Co. KG | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
| DE10304403A1 (de) * | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| JP2006028028A (ja) * | 2004-07-12 | 2006-02-02 | Teikoku Medix Kk | 経口医薬組成物 |
| MX2007007836A (es) | 2004-12-27 | 2007-08-20 | Eisai R&D Man Co Ltd | Metodo para estabilizar un farmaco anti-demencia. |
| PT1962808E (pt) * | 2005-12-14 | 2010-10-29 | Hoffmann La Roche | Formulação de precursor de fármaco para o hcv |
| US20100172989A1 (en) * | 2006-01-21 | 2010-07-08 | Abbott Laboratories | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US20090317355A1 (en) * | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| DE102007009242A1 (de) | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
| DE102007026550A1 (de) * | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
| WO2009087410A2 (en) * | 2008-01-11 | 2009-07-16 | Cipla Limited | Solid pharmaceutical dosage form |
| TW200950776A (en) * | 2008-01-24 | 2009-12-16 | Abbott Gmbh & Co Kg | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US9226907B2 (en) | 2008-02-01 | 2016-01-05 | Abbvie Inc. | Extended release hydrocodone acetaminophen and related methods and uses thereof |
| KR101753222B1 (ko) | 2014-12-12 | 2017-07-04 | 강원대학교산학협력단 | 용융압출하여 제조된 당귀-고체분산체 및 그 제조방법 |
| WO2018111459A1 (en) * | 2016-12-14 | 2018-06-21 | Dow Global Technologies Llc | Method for generating salts of pharmaceutical active ingredients |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
| KR20260007295A (ko) | 2018-05-24 | 2026-01-13 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH668553A5 (de) * | 1987-02-02 | 1989-01-13 | Mepha Ag | Arzneimittel mit verzoegerter wirkstofffreisetzung. |
| US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
| WO1993007859A1 (en) * | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| US5695781A (en) * | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
| AU3404997A (en) | 1996-05-31 | 1998-01-05 | Euro-Celtique S.A. | Sustained release oxycodone formulations with no fed/fast effect |
| US6673367B1 (en) * | 1998-12-17 | 2004-01-06 | Euro-Celtique, S.A. | Controlled/modified release oral methylphenidate formulations |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| JP4938204B2 (ja) | 2001-02-27 | 2012-05-23 | エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング | 貯蔵安定性を改良するための、医薬品配合物用被覆材料および結合材料 |
| DE10239999A1 (de) | 2002-08-27 | 2004-03-04 | Röhm GmbH & Co. KG | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
-
2002
- 2002-02-27 DE DE10208344A patent/DE10208344A1/de not_active Withdrawn
-
2003
- 2003-01-30 US US10/498,829 patent/US8642089B2/en active Active
- 2003-01-30 KR KR1020047013278A patent/KR100707712B1/ko not_active Expired - Lifetime
- 2003-01-30 JP JP2003570829A patent/JP5054278B2/ja not_active Expired - Lifetime
- 2003-01-30 AU AU2003210196A patent/AU2003210196A1/en not_active Abandoned
- 2003-01-30 PL PL370426A patent/PL204465B1/pl unknown
- 2003-01-30 MX MXPA04008345A patent/MXPA04008345A/es active IP Right Grant
- 2003-01-30 DE DE50307321T patent/DE50307321D1/de not_active Expired - Lifetime
- 2003-01-30 IL IL16208203A patent/IL162082A0/xx unknown
- 2003-01-30 ES ES03742925T patent/ES2286447T3/es not_active Expired - Lifetime
- 2003-01-30 EP EP03742925A patent/EP1478344B1/de not_active Expired - Lifetime
- 2003-01-30 CA CA2474691A patent/CA2474691C/en not_active Expired - Lifetime
- 2003-01-30 BR BRPI0307995A patent/BRPI0307995B8/pt not_active IP Right Cessation
- 2003-01-30 AT AT03742925T patent/ATE362754T1/de active
- 2003-01-30 WO PCT/EP2003/000935 patent/WO2003072083A2/de not_active Ceased
-
2004
- 2004-05-20 IL IL162082A patent/IL162082A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2474691A1 (en) | 2003-09-04 |
| AU2003210196A1 (en) | 2003-09-09 |
| JP5054278B2 (ja) | 2012-10-24 |
| EP1478344A2 (de) | 2004-11-24 |
| PL204465B1 (pl) | 2010-01-29 |
| US20040253314A1 (en) | 2004-12-16 |
| DE50307321D1 (de) | 2007-07-05 |
| KR100707712B1 (ko) | 2007-04-16 |
| ATE362754T1 (de) | 2007-06-15 |
| WO2003072083A2 (de) | 2003-09-04 |
| ES2286447T3 (es) | 2007-12-01 |
| WO2003072083A3 (de) | 2004-04-08 |
| CA2474691C (en) | 2011-04-19 |
| EP1478344B1 (de) | 2007-05-23 |
| MXPA04008345A (es) | 2004-11-26 |
| BR0307995A (pt) | 2004-12-07 |
| IL162082A0 (en) | 2005-11-20 |
| BRPI0307995B1 (pt) | 2019-02-26 |
| IL162082A (en) | 2009-11-18 |
| JP2005526731A (ja) | 2005-09-08 |
| US8642089B2 (en) | 2014-02-04 |
| KR20040084936A (ko) | 2004-10-06 |
| DE10208344A1 (de) | 2003-09-04 |
| BRPI0307995B8 (pt) | 2021-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL162082A0 (en) | Melt extrusion consisting of salts of active ingredients | |
| AU4781599A (en) | Coating and excipient agent for oral or dermal dosage forms | |
| KR101500769B1 (ko) | 위액 내성인 활성 물질 매트릭스를 포함하는 펠렛 | |
| AU2003218641A1 (en) | Pharmaceutical dosage form and method for the production thereof | |
| EP0381219B1 (en) | Modified release gemfibrozil composition | |
| CA2407072A1 (en) | Taste masking coating composition | |
| JP5416586B2 (ja) | コーティング製剤の製造方法 | |
| EP0381218B1 (en) | Extended release gemfibrozil composition | |
| AU2003266232A1 (en) | Granulate or powder for producing coating or binding agents for medicaments | |
| NZ505431A (en) | Solid thermoformable controlled-release pharmaceutical composition | |
| CA2339913A1 (en) | Pharmaceutical formulations and method for making | |
| DE69929439D1 (de) | Polyakrylsäure-granulate mit gesteuerter freigabe und verfahren zu dessen herstellung | |
| RU2004127237A (ru) | Твердая препаративная форма с замедленным/контролируемым высвобождением как новая система доставки лекарственного средства со сниженным риском демпинга дозы | |
| DE19753300A1 (de) | Verfahren zur Herstellung von festen Dosierungsformen |