PL370426A1 - Wytłaczanie stopionych soli zawierających składniki czynne - Google Patents
Wytłaczanie stopionych soli zawierających składniki czynneInfo
- Publication number
- PL370426A1 PL370426A1 PL03370426A PL37042603A PL370426A1 PL 370426 A1 PL370426 A1 PL 370426A1 PL 03370426 A PL03370426 A PL 03370426A PL 37042603 A PL37042603 A PL 37042603A PL 370426 A1 PL370426 A1 PL 370426A1
- Authority
- PL
- Poland
- Prior art keywords
- active ingredient
- salts
- granule
- meth
- active ingredients
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 2
- 238000001125 extrusion Methods 0.000 title 1
- 239000008187 granular material Substances 0.000 abstract 3
- 239000000843 powder Substances 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 abstract 1
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 239000000178 monomer Substances 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
- Seasonings (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10208344A DE10208344A1 (de) | 2002-02-27 | 2002-02-27 | Schmelzextrusion von Wirkstoffsalzen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL370426A1 true PL370426A1 (pl) | 2005-05-30 |
| PL204465B1 PL204465B1 (pl) | 2010-01-29 |
Family
ID=27675020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL370426A PL204465B1 (pl) | 2002-02-27 | 2003-01-30 | Sposób wytwarzania granulatów lub proszków zawierających substancje czynne, granulaty lub proszek wytwarzane tym sposobem oraz zastosowanie tych granulatów lub proszków |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8642089B2 (pl) |
| EP (1) | EP1478344B1 (pl) |
| JP (1) | JP5054278B2 (pl) |
| KR (1) | KR100707712B1 (pl) |
| AT (1) | ATE362754T1 (pl) |
| AU (1) | AU2003210196A1 (pl) |
| BR (1) | BRPI0307995B8 (pl) |
| CA (1) | CA2474691C (pl) |
| DE (2) | DE10208344A1 (pl) |
| ES (1) | ES2286447T3 (pl) |
| IL (2) | IL162082A0 (pl) |
| MX (1) | MXPA04008345A (pl) |
| PL (1) | PL204465B1 (pl) |
| WO (1) | WO2003072083A2 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10239999A1 (de) * | 2002-08-27 | 2004-03-04 | Röhm GmbH & Co. KG | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
| DE10304403A1 (de) | 2003-01-28 | 2004-08-05 | Röhm GmbH & Co. KG | Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung |
| US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
| US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
| JP2006028028A (ja) * | 2004-07-12 | 2006-02-02 | Teikoku Medix Kk | 経口医薬組成物 |
| US8481565B2 (en) | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| ATE482690T1 (de) * | 2005-12-14 | 2010-10-15 | Hoffmann La Roche | Hcv-prodrug-formulierung |
| US20090317355A1 (en) * | 2006-01-21 | 2009-12-24 | Abbott Gmbh & Co. Kg, | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| US20100172989A1 (en) * | 2006-01-21 | 2010-07-08 | Abbott Laboratories | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| DE102007009242A1 (de) * | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
| DE102007026550A1 (de) | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
| CA2712010A1 (en) * | 2008-01-11 | 2009-07-12 | Cipla Limited | Solid pharmaceutical dosage form |
| TW200950776A (en) * | 2008-01-24 | 2009-12-16 | Abbott Gmbh & Co Kg | Abuse resistant melt extruded formulation having reduced alcohol interaction |
| JP2011511782A (ja) | 2008-02-12 | 2011-04-14 | アボット・ラボラトリーズ | 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途 |
| KR101753222B1 (ko) | 2014-12-12 | 2017-07-04 | 강원대학교산학협력단 | 용융압출하여 제조된 당귀-고체분산체 및 그 제조방법 |
| WO2018111459A1 (en) * | 2016-12-14 | 2018-06-21 | Dow Global Technologies Llc | Method for generating salts of pharmaceutical active ingredients |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| AU2019275406B2 (en) | 2018-05-24 | 2024-11-14 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| WO2019226519A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
| WO2022231930A1 (en) | 2021-04-26 | 2022-11-03 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH668553A5 (de) * | 1987-02-02 | 1989-01-13 | Mepha Ag | Arzneimittel mit verzoegerter wirkstofffreisetzung. |
| US5084278A (en) * | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
| WO1993007859A1 (en) * | 1991-10-23 | 1993-04-29 | Warner-Lambert Company | Novel pharmaceutical pellets and process for their production |
| US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| US5695781A (en) * | 1995-03-01 | 1997-12-09 | Hallmark Pharmaceuticals, Inc. | Sustained release formulation containing three different types of polymers |
| AU3404997A (en) * | 1996-05-31 | 1998-01-05 | Euro-Celtique S.A. | Sustained release oxycodone formulations with no fed/fast effect |
| US6673367B1 (en) | 1998-12-17 | 2004-01-06 | Euro-Celtique, S.A. | Controlled/modified release oral methylphenidate formulations |
| DE19958007A1 (de) | 1999-12-02 | 2001-06-07 | Roehm Gmbh | Spritzgußverfahren für (Meth)acrylat-Copolymere mit teritiären Ammoniumgruppen |
| HU229344B1 (en) | 2001-02-27 | 2013-11-28 | Evonik Roehm Gmbh | Coating and binding agent for pharmaceutical formulations with improved storage stability |
| DE10239999A1 (de) | 2002-08-27 | 2004-03-04 | Röhm GmbH & Co. KG | Granulat oder Pulver zur Herstellung von Überzugs- und Bindemitteln für Arzneiformen |
-
2002
- 2002-02-27 DE DE10208344A patent/DE10208344A1/de not_active Withdrawn
-
2003
- 2003-01-30 PL PL370426A patent/PL204465B1/pl unknown
- 2003-01-30 AT AT03742925T patent/ATE362754T1/de active
- 2003-01-30 WO PCT/EP2003/000935 patent/WO2003072083A2/de not_active Ceased
- 2003-01-30 JP JP2003570829A patent/JP5054278B2/ja not_active Expired - Lifetime
- 2003-01-30 KR KR1020047013278A patent/KR100707712B1/ko not_active Expired - Lifetime
- 2003-01-30 IL IL16208203A patent/IL162082A0/xx unknown
- 2003-01-30 US US10/498,829 patent/US8642089B2/en active Active
- 2003-01-30 MX MXPA04008345A patent/MXPA04008345A/es active IP Right Grant
- 2003-01-30 BR BRPI0307995A patent/BRPI0307995B8/pt not_active IP Right Cessation
- 2003-01-30 AU AU2003210196A patent/AU2003210196A1/en not_active Abandoned
- 2003-01-30 EP EP03742925A patent/EP1478344B1/de not_active Expired - Lifetime
- 2003-01-30 DE DE50307321T patent/DE50307321D1/de not_active Expired - Lifetime
- 2003-01-30 ES ES03742925T patent/ES2286447T3/es not_active Expired - Lifetime
- 2003-01-30 CA CA2474691A patent/CA2474691C/en not_active Expired - Lifetime
-
2004
- 2004-05-20 IL IL162082A patent/IL162082A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ATE362754T1 (de) | 2007-06-15 |
| IL162082A0 (en) | 2005-11-20 |
| CA2474691A1 (en) | 2003-09-04 |
| CA2474691C (en) | 2011-04-19 |
| WO2003072083A2 (de) | 2003-09-04 |
| DE50307321D1 (de) | 2007-07-05 |
| PL204465B1 (pl) | 2010-01-29 |
| EP1478344A2 (de) | 2004-11-24 |
| ES2286447T3 (es) | 2007-12-01 |
| IL162082A (en) | 2009-11-18 |
| KR100707712B1 (ko) | 2007-04-16 |
| US8642089B2 (en) | 2014-02-04 |
| BR0307995A (pt) | 2004-12-07 |
| US20040253314A1 (en) | 2004-12-16 |
| WO2003072083A3 (de) | 2004-04-08 |
| JP2005526731A (ja) | 2005-09-08 |
| DE10208344A1 (de) | 2003-09-04 |
| BRPI0307995B1 (pt) | 2019-02-26 |
| BRPI0307995B8 (pt) | 2021-05-25 |
| JP5054278B2 (ja) | 2012-10-24 |
| AU2003210196A1 (en) | 2003-09-09 |
| MXPA04008345A (es) | 2004-11-26 |
| KR20040084936A (ko) | 2004-10-06 |
| EP1478344B1 (de) | 2007-05-23 |
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