PL3719013T3 - Pochodna sulfamidowa pirymidyny oraz sposób jej wytwarzania i zastosowanie medyczne - Google Patents

Pochodna sulfamidowa pirymidyny oraz sposób jej wytwarzania i zastosowanie medyczne

Info

Publication number
PL3719013T3
PL3719013T3 PL18881280.4T PL18881280T PL3719013T3 PL 3719013 T3 PL3719013 T3 PL 3719013T3 PL 18881280 T PL18881280 T PL 18881280T PL 3719013 T3 PL3719013 T3 PL 3719013T3
Authority
PL
Poland
Prior art keywords
preparation
medical application
sulfamide derivative
pyrimidine
pyrimidine sulfamide
Prior art date
Application number
PL18881280.4T
Other languages
English (en)
Inventor
Yunfu Luo
Maoyi LEI
Junmiao LI
Yu Xu
Ran Wei
Shuhui Chen
Original Assignee
Wuxi Biocity Biopharmaceutics Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuxi Biocity Biopharmaceutics Co., Ltd. filed Critical Wuxi Biocity Biopharmaceutics Co., Ltd.
Publication of PL3719013T3 publication Critical patent/PL3719013T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL18881280.4T 2017-11-21 2018-11-19 Pochodna sulfamidowa pirymidyny oraz sposób jej wytwarzania i zastosowanie medyczne PL3719013T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201711168111 2017-11-21
PCT/CN2018/116196 WO2019101039A1 (zh) 2017-11-21 2018-11-19 嘧啶磺酰胺类衍生物、其制备方法及其在医药上的应用

Publications (1)

Publication Number Publication Date
PL3719013T3 true PL3719013T3 (pl) 2023-05-08

Family

ID=66630436

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18881280.4T PL3719013T3 (pl) 2017-11-21 2018-11-19 Pochodna sulfamidowa pirymidyny oraz sposób jej wytwarzania i zastosowanie medyczne

Country Status (18)

Country Link
US (1) US11319305B2 (pl)
EP (1) EP3719013B1 (pl)
JP (1) JP7245832B2 (pl)
CN (1) CN111479808B (pl)
AU (1) AU2018372752B2 (pl)
DK (1) DK3719013T3 (pl)
ES (1) ES2936864T3 (pl)
FI (1) FI3719013T3 (pl)
HR (1) HRP20230318T1 (pl)
HU (1) HUE061515T2 (pl)
IL (1) IL274773B2 (pl)
LT (1) LT3719013T (pl)
PL (1) PL3719013T3 (pl)
PT (1) PT3719013T (pl)
RS (1) RS64040B1 (pl)
SI (1) SI3719013T1 (pl)
SM (1) SMT202300100T1 (pl)
WO (1) WO2019101039A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109232546B (zh) * 2018-09-25 2020-09-04 中国人民解放军总医院 一种嘧啶磺酰胺类衍生物的医药用途
PL3974421T3 (pl) 2019-05-22 2024-11-04 Wuxi Biocity Biopharmaceutics Co., Ltd. Krystaliczna postać związku sulfonamidu pirymidyny i sposób jego otrzymywania
CN120271660B (zh) * 2025-06-09 2025-08-19 杭州肽佳生物科技有限公司 一种高效选择性拮抗剂bq-788的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2315614C (en) * 1999-07-29 2004-11-02 Pfizer Inc. Pyrazoles
EP1160248A1 (en) * 2000-05-31 2001-12-05 Pfizer Inc. N-(Isoxazol-5-yl)-sulfonamide derivatives and their use as endothelin antagonists
JP3490959B2 (ja) 2000-07-11 2004-01-26 三洋電機株式会社 受光素子及び受光モジュール
EP1693372A1 (en) 2000-12-18 2006-08-23 Actelion Pharmaceuticals Ltd. Novel Sulfamides and their use as endothelin receptor antagonists
NZ540937A (en) 2002-12-02 2008-06-30 Actelion Pharmaceuticals Ltd Pyrimidine-sulfamides and their use as endothelian receptor antagonist
TW200628467A (en) * 2004-11-11 2006-08-16 Actelion Pharmaceuticals Ltd Novel sulfamides

Also Published As

Publication number Publication date
US11319305B2 (en) 2022-05-03
JP7245832B2 (ja) 2023-03-24
CA3083019A1 (en) 2019-05-31
EP3719013A4 (en) 2021-04-21
EP3719013A1 (en) 2020-10-07
IL274773B2 (en) 2023-08-01
AU2018372752A1 (en) 2020-07-02
IL274773A (en) 2020-07-30
AU2018372752B2 (en) 2023-02-02
DK3719013T3 (da) 2023-04-03
EP3719013B1 (en) 2023-01-04
RU2020119900A (ru) 2021-12-23
HRP20230318T1 (hr) 2023-05-12
JP2021504330A (ja) 2021-02-15
SI3719013T1 (sl) 2023-05-31
SMT202300100T1 (it) 2023-05-12
CN111479808B (zh) 2023-02-24
WO2019101039A1 (zh) 2019-05-31
US20200283425A1 (en) 2020-09-10
HUE061515T2 (hu) 2023-07-28
CN111479808A (zh) 2020-07-31
PT3719013T (pt) 2023-02-01
BR112020010149A8 (pt) 2023-01-17
RS64040B1 (sr) 2023-04-28
IL274773B1 (en) 2023-04-01
BR112020010149A2 (pt) 2020-11-10
RU2020119900A3 (pl) 2021-12-23
FI3719013T3 (fi) 2023-04-03
ES2936864T3 (es) 2023-03-22
LT3719013T (lt) 2023-05-10

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