PL3720442T3 - Hamowanie mutanta idh-1 - Google Patents
Hamowanie mutanta idh-1Info
- Publication number
- PL3720442T3 PL3720442T3 PL19728271.8T PL19728271T PL3720442T3 PL 3720442 T3 PL3720442 T3 PL 3720442T3 PL 19728271 T PL19728271 T PL 19728271T PL 3720442 T3 PL3720442 T3 PL 3720442T3
- Authority
- PL
- Poland
- Prior art keywords
- idh
- mutant
- inhibition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862672461P | 2018-05-16 | 2018-05-16 | |
| US201862672462P | 2018-05-16 | 2018-05-16 | |
| US201862680566P | 2018-06-04 | 2018-06-04 | |
| US201862680571P | 2018-06-04 | 2018-06-04 | |
| US201862680560P | 2018-06-04 | 2018-06-04 | |
| US201862680562P | 2018-06-04 | 2018-06-04 | |
| US201862692604P | 2018-06-29 | 2018-06-29 | |
| US201862692591P | 2018-06-29 | 2018-06-29 | |
| US201862692601P | 2018-06-29 | 2018-06-29 | |
| US201862692598P | 2018-06-29 | 2018-06-29 | |
| US201862692605P | 2018-06-29 | 2018-06-29 | |
| US201862773562P | 2018-11-30 | 2018-11-30 | |
| US201962798687P | 2019-01-30 | 2019-01-30 | |
| US201962798677P | 2019-01-30 | 2019-01-30 | |
| US201962798681P | 2019-01-30 | 2019-01-30 | |
| US201962798690P | 2019-01-30 | 2019-01-30 | |
| US201962798684P | 2019-01-30 | 2019-01-30 | |
| US201962812367P | 2019-03-01 | 2019-03-01 | |
| PCT/US2019/032747 WO2019222553A1 (en) | 2018-05-16 | 2019-05-16 | Inhibiting mutant idh-1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3720442T3 true PL3720442T3 (pl) | 2023-05-29 |
Family
ID=85705783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19728271.8T PL3720442T3 (pl) | 2018-05-16 | 2019-05-16 | Hamowanie mutanta idh-1 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20260060975A1 (pl) |
| EP (1) | EP4215197A1 (pl) |
| DK (1) | DK3720442T3 (pl) |
| ES (1) | ES2941079T3 (pl) |
| FI (1) | FI3720442T3 (pl) |
| HR (1) | HRP20230168T1 (pl) |
| LT (1) | LT3720442T (pl) |
| MD (1) | MD3720442T2 (pl) |
| PL (1) | PL3720442T3 (pl) |
| RS (1) | RS64069B1 (pl) |
| SI (1) | SI3720442T1 (pl) |
| SM (1) | SMT202300073T1 (pl) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX372964B (es) | 2014-09-19 | 2020-03-27 | Forma Therapeutics Inc | Derivados de fenil quinolinona como inhibidores de isocitrato deshidrogenasa mutante (mt-idh) |
| MA53352A (fr) | 2014-09-19 | 2021-09-15 | Forma Therapeutics Inc | Dérivés de pyridin-2-(1h)-one-quinolinone en tant qu'inhibiteurs d'isocitrate déshydrogénase |
| AU2015317327B9 (en) | 2014-09-19 | 2020-04-09 | Forma Therapeutics, Inc. | Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
| US9624175B2 (en) | 2015-04-21 | 2017-04-18 | Forma Therapeutics, Inc. | Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
| US10407419B2 (en) | 2015-04-21 | 2019-09-10 | Forma Therapeutics, Inc. | Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase inhibitors |
-
2019
- 2019-05-16 HR HRP20230168TT patent/HRP20230168T1/hr unknown
- 2019-05-16 ES ES19728271T patent/ES2941079T3/es active Active
- 2019-05-16 SM SM20230073T patent/SMT202300073T1/it unknown
- 2019-05-16 SI SI201930471T patent/SI3720442T1/sl unknown
- 2019-05-16 DK DK19728271.8T patent/DK3720442T3/da active
- 2019-05-16 RS RS20230221A patent/RS64069B1/sr unknown
- 2019-05-16 PL PL19728271.8T patent/PL3720442T3/pl unknown
- 2019-05-16 MD MDE20201055T patent/MD3720442T2/ro unknown
- 2019-05-16 EP EP22216450.1A patent/EP4215197A1/en active Pending
- 2019-05-16 LT LTEPPCT/US2019/032747T patent/LT3720442T/lt unknown
- 2019-05-16 FI FIEP19728271.8T patent/FI3720442T3/fi active
-
2025
- 2025-03-12 US US19/078,066 patent/US20260060975A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FI3720442T3 (fi) | 2023-03-17 |
| HRP20230168T1 (hr) | 2023-05-12 |
| LT3720442T (lt) | 2023-04-25 |
| EP4215197A1 (en) | 2023-07-26 |
| MD3720442T2 (ro) | 2023-09-30 |
| DK3720442T3 (da) | 2023-03-27 |
| SMT202300073T1 (it) | 2023-05-12 |
| US20260060975A1 (en) | 2026-03-05 |
| RS64069B1 (sr) | 2023-04-28 |
| ES2941079T3 (es) | 2023-05-16 |
| SI3720442T1 (sl) | 2023-06-30 |
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