PL372409A1 - Nowe pochodne alkoksypirydyny - Google Patents

Nowe pochodne alkoksypirydyny

Info

Publication number: PL372409A1
Authority: PL; Poland
Prior art keywords: alkoxypyridine; derivatives; novel; purin; imidazo
Prior art date: 2002-03-27

Application number

PL03372409A

Other languages

English (en)

Inventor

Wolf-Rüdiger Ulrich

Rainer Boer

Degenhard Marx

Manfrid Eltze

Thomas Klein

Rüdiger Nave

Ulrich Grädler

Thomas Fuchss

Johannes Barsig

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-27

Filing date

2003-03-25

Publication date

2005-07-25

2003-03-25 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2005-07-25 Publication of PL372409A1 publication Critical patent/PL372409A1/pl

Links

-1 3H-imidazo[4,5-b]pyridin-2-yl Chemical group 0.000 abstract 4
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
102100029438 Nitric oxide synthase, inducible Human genes 0.000 abstract 1
101710089543 Nitric oxide synthase, inducible Proteins 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Immunology (AREA)
Ophthalmology & Optometry (AREA)
Psychology (AREA)
Cardiology (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Vascular Medicine (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
Psychiatry (AREA)
Transplantation (AREA)
Pulmonology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)

PL03372409A 2002-03-27 2003-03-25 Nowe pochodne alkoksypirydyny PL372409A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02007049		2002-03-27

Publications (1)

Publication Number	Publication Date
PL372409A1 true PL372409A1 (pl)	2005-07-25

Family

ID=28051741

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL03372409A PL372409A1 (pl)	2002-03-27	2003-03-25	Nowe pochodne alkoksypirydyny

Country Status (18)

Country	Link
US (1)	US7138399B2 (pl)
EP (1)	EP1490366B1 (pl)
JP (1)	JP4448695B2 (pl)
KR (1)	KR20050002910A (pl)
CN (1)	CN1307176C (pl)
AT (1)	ATE384722T1 (pl)
AU (1)	AU2003226706A1 (pl)
BR (1)	BR0308785A (pl)
CA (1)	CA2480385A1 (pl)
DE (1)	DE60318826T2 (pl)
ES (1)	ES2300599T3 (pl)
IL (1)	IL163625A0 (pl)
MX (1)	MXPA04009283A (pl)
NO (1)	NO20044633L (pl)
NZ (1)	NZ535959A (pl)
PL (1)	PL372409A1 (pl)
WO (1)	WO2003080607A1 (pl)
ZA (1)	ZA200407766B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2540083A1 (en) *	2003-10-01	2005-04-07	Altana Pharma Ag	Imidazopyridine-derivatives as inductible no-synthase inhibitors
CN1856494A (zh) *	2003-10-01	2006-11-01	奥坦纳医药公司	作为诱导型no－合酶抑制剂的咪唑并吡啶类衍生物
JP2007507463A (ja) *	2003-10-01	2007-03-29	アルタナ　ファルマ　アクチエンゲゼルシャフト	誘導性ＮＯシンターゼ阻害剤としてのイミダゾ［４，５−ｂ］ピリジン誘導体
US7279488B2 (en)	2003-10-01	2007-10-09	Nycomed Gmbh	Imidazopyridine-derivatives as inducible no-synthase inhibitors
BRPI0415034A (pt) *	2003-10-01	2006-12-12	Altana Pharma Ag	derivados de aminopiridina como inibidores de não-sintase induzìveis
US8088935B2 (en)	2003-12-23	2012-01-03	Ironwood Pharmaceuticals, Inc.	Compounds and methods for the treatment of asthma
PL1753512T3 (pl)	2004-05-28	2009-03-31	4Sc Ag	Tetrahydropirydotiofeny
WO2005120642A2 (en)	2004-06-11	2005-12-22	Altana Pharma Ag	Tetrahydropyridothiophenes for treating hyperproliferative disorders
EP1851229A1 (en)	2005-02-09	2007-11-07	Nycomed GmbH	Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
WO2006084904A1 (en)	2005-02-11	2006-08-17	Nycomed Gmbh	Tetrahydropyridothiophenes as antripoliferative agents for the treatment of cancer
JP2008534555A (ja) *	2005-03-31	2008-08-28	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	ｉＮＯＳインヒビターとして有用なイミダゾピリジン誘導体
JP2008542243A (ja)	2005-05-25	2008-11-27	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	新規のテトラヒドロピリドチオフェン
JP2008542242A (ja)	2005-05-25	2008-11-27	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	新規のテトラヒドロピリドチオフェン
UY29825A1 (es) *	2005-10-03	2007-05-31	Astrazeneca Ab	Derivados sustituidos de 3h-imidazol-(4,5 b (beta))piridina-2-il benzoatos y benzamidas, composiciones farmacéuticas que los contienen y aplicaciones
UY29823A1 (es) *	2005-10-03	2007-05-31	Astrazeneca Ab	Derivados sustituidos de 7-cloro-3h-imidazol-(4,5-b) piridina, composiciones farmacéuticas que los contienen, procesos para la preparación de los mismos y aplicaciones
WO2008031788A1 (en) *	2006-09-12	2008-03-20	Nycomed Gmbh	Aminoazepine derivatives as highly efficient inhibitors of the inducible nitric oxide synthase
US20080139608A1 (en) *	2006-12-06	2008-06-12	Universiteit Leiden	2,6,8, Trisubstituted 1-deazapurines and their different uses
CA2826649C (en) *	2011-02-25	2016-07-26	Merck Sharp & Dohme Corp.	Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
EP3495366A1 (en) *	2011-07-15	2019-06-12	Shionogi & Co., Ltd	Azabenzimidazole derivative having ampk-activating activity
GB201512635D0 (en)	2015-07-17	2015-08-26	Ucl Business Plc	Uses of therapeutic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv) *	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
GB8307865D0 (en) *	1983-03-22	1983-04-27	Fujisawa Pharmaceutical Co	Benzimidazole derivatives
GB8515934D0 (en) *	1985-06-24	1985-07-24	Janssen Pharmaceutica Nv	(4-piperidinomethyl and-hetero)purines
SE512835C2 (sv) *	1996-01-08	2000-05-22	Astrazeneca Ab	Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare

2003
- 2003-03-25 JP JP2003578361A patent/JP4448695B2/ja not_active Expired - Fee Related
- 2003-03-25 ES ES03744851T patent/ES2300599T3/es not_active Expired - Lifetime
- 2003-03-25 AT AT03744851T patent/ATE384722T1/de not_active IP Right Cessation
- 2003-03-25 US US10/509,396 patent/US7138399B2/en not_active Expired - Fee Related
- 2003-03-25 IL IL16362503A patent/IL163625A0/xx unknown
- 2003-03-25 EP EP03744851A patent/EP1490366B1/en not_active Expired - Lifetime
- 2003-03-25 BR BR0308785-9A patent/BR0308785A/pt not_active IP Right Cessation
- 2003-03-25 NZ NZ535959A patent/NZ535959A/en not_active IP Right Cessation
- 2003-03-25 DE DE60318826T patent/DE60318826T2/de not_active Expired - Lifetime
- 2003-03-25 AU AU2003226706A patent/AU2003226706A1/en not_active Abandoned
- 2003-03-25 CA CA002480385A patent/CA2480385A1/en not_active Abandoned
- 2003-03-25 PL PL03372409A patent/PL372409A1/pl not_active Application Discontinuation
- 2003-03-25 KR KR10-2004-7015438A patent/KR20050002910A/ko not_active Ceased
- 2003-03-25 WO PCT/EP2003/003076 patent/WO2003080607A1/en not_active Ceased
- 2003-03-25 MX MXPA04009283A patent/MXPA04009283A/es active IP Right Grant
- 2003-03-25 CN CNB038069172A patent/CN1307176C/zh not_active Expired - Fee Related
2004
- 2004-09-27 ZA ZA200407766A patent/ZA200407766B/en unknown
- 2004-10-27 NO NO20044633A patent/NO20044633L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE60318826D1 (de)	2008-03-13
EP1490366A1 (en)	2004-12-29
HK1078850A1 (en)	2006-03-24
EP1490366B1 (en)	2008-01-23
WO2003080607A1 (en)	2003-10-02
ZA200407766B (en)	2006-06-28
US20050171125A1 (en)	2005-08-04
CN1307176C (zh)	2007-03-28
BR0308785A (pt)	2005-01-11
NZ535959A (en)	2006-05-26
ATE384722T1 (de)	2008-02-15
JP2005525388A (ja)	2005-08-25
CN1642955A (zh)	2005-07-20
CA2480385A1 (en)	2003-10-02
KR20050002910A (ko)	2005-01-10
IL163625A0 (en)	2005-12-18
ES2300599T3 (es)	2008-06-16
NO20044633L (no)	2004-12-23
US7138399B2 (en)	2006-11-21
AU2003226706A1 (en)	2003-10-08
DE60318826T2 (de)	2009-01-22
JP4448695B2 (ja)	2010-04-14
MXPA04009283A (es)	2005-01-25

Legal Events

Date	Code	Title	Description
2010-12-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL372409A1 (pl)	2005-07-25	Nowe pochodne alkoksypirydyny
AU2002246728A1 (en)	2002-08-28	Carboline derivatives
AU7779900A (en)	2001-04-30	Trifluoromethyl-substituted spirocyclic ketoenols
AU2002319814A1 (en)	2003-03-03	Substituted 1h-dihydropyrazoles, their preparation and use
TW200738672A (en)	2007-10-16	Intermediated for the preparation of 4,5-dihydro-pyrazolo [3,4-c] pyrid-2-ones
MXPA04001323A (es)	2004-05-20	Dihidro-3-halo-1h-pirazol-5-carboxilatos sustituidos, su preparacion y uso.
AU2002249890A1 (en)	2002-08-28	Carboline derivatives
MXPA02012076A (es)	2003-06-06	Compuestos quimicos.
MXPA02012659A (es)	2003-09-22	Derivados de pirazindiona condensados.
AR029214A1 (es)	2003-06-18	Compuestos inhibidores de fosfodiesterasa - 4: 8 - arilquinolinas sustituidas, composiciones farmaceuticas, metodo de tratamiento que las utiliza
MXPA03003923A (es)	2004-05-05	Compuestos de n-([1,2,4]triazoloazinil)tiofensulfonamida como herbicidas.
IL173810A0 (en)	2006-07-05	Imidazopyridine derivatives and pharmaceutical compositions containing the same
AU2001263278A1 (en)	2002-01-08	Cyclic gmp-specific phosphodiesterase inhibitors
MXPA05012951A (es)	2006-02-13	Triazolopirimidinas.
AU2002213419A1 (en)	2002-04-15	Condensed pyridoindole derivatives
MXPA03001356A (es)	2004-04-05	Nuevos agentes inhibidores de beta-amiloides, procedimientos para su preparacion y su uso como medicamentos.
ATE356131T1 (de)	2007-03-15	Tricyclische imidazopyridine
DE60008400D1 (de)	2004-03-25	Triazolopyrimidinderivate
CA2309474A1 (en)	2000-11-28	New 4-arylpiperidine derivatives for the treatment of pruritus
SI1377574T1 (pl)	2005-08-31
MXPA02012472A (es)	2004-01-26	Compuestos quimicos.
MXPA06003345A (es)	2006-06-08	Derivados de aminopiridina como inhibidores de la no-sintasa inducible.
MXPA06000372A (es)	2006-03-30	Compuestos de silicio y su uso.
IL173895A0 (en)	2006-07-05	Imidazopyridine derivatives and pharmaceutical compositions containing the same
BRPI0415038A (pt)	2006-12-12	derivados de imidazo (4,5-b) piridina como inibidores sem ser da sintase que podem ser induzidos