PL374484A1 - Sposoby wytwarzania immunoefektorów fosforanów aminoalkiloglukozaminidowych i disacharydów oraz półprodukty do tego sposobu - Google Patents
Sposoby wytwarzania immunoefektorów fosforanów aminoalkiloglukozaminidowych i disacharydów oraz półprodukty do tego sposobuInfo
- Publication number
- PL374484A1 PL374484A1 PL03374484A PL37448403A PL374484A1 PL 374484 A1 PL374484 A1 PL 374484A1 PL 03374484 A PL03374484 A PL 03374484A PL 37448403 A PL37448403 A PL 37448403A PL 374484 A1 PL374484 A1 PL 374484A1
- Authority
- PL
- Poland
- Prior art keywords
- immunoeffectors
- disaccharide
- processes
- production
- intermediates therefor
- Prior art date
Links
- 229910019142 PO4 Inorganic materials 0.000 title 1
- 125000004103 aminoalkyl group Chemical group 0.000 title 1
- 150000002016 disaccharides Chemical class 0.000 title 1
- 150000008271 glucosaminides Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title 1
- 239000010452 phosphate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39448702P | 2002-07-08 | 2002-07-08 | |
| US43858503P | 2003-01-06 | 2003-01-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL374484A1 true PL374484A1 (pl) | 2005-10-31 |
| PL220778B1 PL220778B1 (pl) | 2016-01-29 |
Family
ID=30118421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL374484A PL220778B1 (pl) | 2002-07-08 | 2003-07-08 | Sposoby wytwarzania 4-fosforanu aminoalkiloglukozaminidu oraz związki pośrednie |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7232900B2 (pl) |
| EP (1) | EP1521762B1 (pl) |
| JP (2) | JP2005536493A (pl) |
| KR (2) | KR20050037460A (pl) |
| CN (1) | CN100497364C (pl) |
| AU (1) | AU2003251824B8 (pl) |
| BR (1) | BR0312656A (pl) |
| CA (1) | CA2492446A1 (pl) |
| ES (1) | ES2456066T3 (pl) |
| IL (2) | IL166178A0 (pl) |
| MX (1) | MXPA05000407A (pl) |
| NZ (1) | NZ537655A (pl) |
| PL (1) | PL220778B1 (pl) |
| RU (1) | RU2340621C2 (pl) |
| WO (1) | WO2004005308A2 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2456066T3 (es) | 2002-07-08 | 2014-04-21 | Corixa Corporation | Procesos para la producción de fosfato de aminoalquil glucosaminida e inmunoefectores disacáridos, e intermedios para ello |
| US7288640B2 (en) | 2002-07-08 | 2007-10-30 | Corixa Corporation | Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor |
| AU2002950657A0 (en) * | 2002-08-08 | 2002-09-12 | Alchemia Limited | Derivatives of monosaccharides for drug discovery |
| AU2002951995A0 (en) * | 2002-10-11 | 2002-10-31 | Alchemia Limited | Classes of compounds that interact with gpcrs |
| US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
| CN101863930A (zh) * | 2003-01-06 | 2010-10-20 | 科里克萨有限公司 | 一些氨烷基氨基葡糖苷磷酸酯化合物和它们的用途 |
| KR101168053B1 (ko) | 2009-11-06 | 2012-07-24 | 연세대학교 산학협력단 | 효율적이고 보편적인 전분화능 줄기세포의 신경세포 분화 유도방법 |
| JP6326825B2 (ja) * | 2013-02-18 | 2018-05-23 | 住友化学株式会社 | 塩、レジスト組成物及びレジストパターンの製造方法 |
| CN105188710A (zh) | 2013-03-15 | 2015-12-23 | 葛兰素史密丝克莱恩生物有限公司 | 包含缓冲的氨基烷基氨基葡糖苷磷酸酯衍生物的组合物及其用于增强免疫应答的用途 |
| WO2014205115A2 (en) | 2013-06-19 | 2014-12-24 | The Regents Of The University Of California | Regioselective silyl exchange of per-silylated oligosaccharides |
| JP7362667B2 (ja) | 2018-02-12 | 2023-10-17 | イニミューン・コーポレーション | Ｔｏｌｌ様受容体リガンド |
| CN114685277A (zh) * | 2020-12-31 | 2022-07-01 | 苏州瑞博生物技术股份有限公司 | 化合物及羟基丙酸盐类化合物的纯化方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4436728A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4436727A (en) | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
| US4987237A (en) | 1983-08-26 | 1991-01-22 | Ribi Immunochem Research, Inc. | Derivatives of monophosphoryl lipid A |
| JPS6153295A (ja) | 1984-08-24 | 1986-03-17 | Dai Ichi Seiyaku Co Ltd | ジサツカライド誘導体 |
| US4613590A (en) | 1985-08-19 | 1986-09-23 | Abbott Laboratories | Amino D-manno-2-octulopyranosidonate containing compounds, pharmaceutical compositions and method of use |
| US4746742A (en) * | 1985-11-28 | 1988-05-24 | Toho Yakuhin Kogyo Kabushiki Kaisha | Analogs of nonreducing monosaccharide moiety of lipid A |
| JPH0757762B2 (ja) * | 1987-09-10 | 1995-06-21 | 理化学研究所 | オリゴガラクチュロン酸およびその製造法 |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5597573A (en) * | 1989-05-04 | 1997-01-28 | Igen, Inc. | Lipid-A analogs: new monosaccharide and disaccharide intermediates for eliciting therapeutic antibodies and for antitumor and antiviral activities |
| JP2933359B2 (ja) * | 1990-07-18 | 1999-08-09 | 理化学研究所 | ＮｅｕＡｃα２→６Ｇａ１ＮＡｃα１→３Ｓｅｒ構造を含むオリゴペプチドの合成法 |
| US5843463A (en) * | 1990-12-21 | 1998-12-01 | Antexbiologics, Inc. | Adhesin-oligosaccharide conjugate vaccine for Haemophilus influenzae |
| JPH06293790A (ja) * | 1993-04-08 | 1994-10-21 | Kyowa Hakko Kogyo Co Ltd | 生理活性物質イノシトールグリカン |
| PL181241B1 (pl) * | 1993-11-17 | 2001-06-29 | Deutsche Om Arzneimittel Gmbh | Disacharydy beta(1 6)glukozoaminowe, sposób wytwarzania disacharydu beta(1 6) glukozoaminowego, zawierająca je kompozycja farmaceutyczna i środek immunomodulujący i/lub przeciwnowotworowy oraz szczepionka |
| JPH0851998A (ja) * | 1994-08-10 | 1996-02-27 | Otsuka Pharmaceut Co Ltd | 糖転移酵素の活性測定法 |
| JPH08245681A (ja) * | 1995-03-03 | 1996-09-24 | Sumitomo Pharmaceut Co Ltd | グルコサミン誘導体及びその製造方法 |
| CA2247115C (en) | 1996-03-01 | 2008-11-18 | The Regents Of The University Of California | Inhibition of selectin binding |
| US6355257B1 (en) * | 1997-05-08 | 2002-03-12 | Corixa Corporation | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6113918A (en) * | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6303347B1 (en) * | 1997-05-08 | 2001-10-16 | Corixa Corporation | Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors |
| US6103640A (en) | 1997-09-12 | 2000-08-15 | Bridgestone Corporation | Electromagnetic-wave shielding and light transmitting plate |
| US6107492A (en) * | 1998-05-08 | 2000-08-22 | Ucb, S.A. | Process for the preparation of levetiracetam |
| US6013640A (en) * | 1998-08-21 | 2000-01-11 | Ribi Immunochem Research, Inc. | Phosphoglycolipid and methods for its use |
| JP4913272B2 (ja) * | 1999-01-07 | 2012-04-11 | 生化学工業株式会社 | オリゴ糖の製造方法ならびに新規オリゴ糖およびそれを含む医薬組成物 |
| JP2001151790A (ja) * | 1999-11-25 | 2001-06-05 | Sankyo Co Ltd | セラミド脂質部位を有する新規なｇｌａ−６０類縁体 |
| HU230847B1 (en) | 2000-05-19 | 2018-08-28 | Corixa Corp | Prophylactic and therapeutic treatment of infectious and other diseases with mono and disaccharide-based compounds |
| CA2417806C (en) | 2000-08-04 | 2011-05-10 | Corixa Corporation | New immunoeffector compounds |
| US6525028B1 (en) * | 2002-02-04 | 2003-02-25 | Corixa Corporation | Immunoeffector compounds |
| ES2456066T3 (es) | 2002-07-08 | 2014-04-21 | Corixa Corporation | Procesos para la producción de fosfato de aminoalquil glucosaminida e inmunoefectores disacáridos, e intermedios para ello |
-
2003
- 2003-07-08 ES ES03763418.5T patent/ES2456066T3/es not_active Expired - Lifetime
- 2003-07-08 RU RU2005102938/04A patent/RU2340621C2/ru active
- 2003-07-08 JP JP2004520086A patent/JP2005536493A/ja active Pending
- 2003-07-08 EP EP03763418.5A patent/EP1521762B1/en not_active Expired - Lifetime
- 2003-07-08 CN CNB038198002A patent/CN100497364C/zh not_active Expired - Lifetime
- 2003-07-08 BR BR0312656-0A patent/BR0312656A/pt not_active Application Discontinuation
- 2003-07-08 CA CA002492446A patent/CA2492446A1/en not_active Abandoned
- 2003-07-08 IL IL16617803A patent/IL166178A0/xx active IP Right Grant
- 2003-07-08 MX MXPA05000407A patent/MXPA05000407A/es active IP Right Grant
- 2003-07-08 US US10/472,991 patent/US7232900B2/en not_active Expired - Lifetime
- 2003-07-08 NZ NZ537655A patent/NZ537655A/en not_active IP Right Cessation
- 2003-07-08 WO PCT/US2003/021504 patent/WO2004005308A2/en not_active Ceased
- 2003-07-08 KR KR1020057000298A patent/KR20050037460A/ko not_active Ceased
- 2003-07-08 AU AU2003251824A patent/AU2003251824B8/en not_active Expired
- 2003-07-08 PL PL374484A patent/PL220778B1/pl unknown
- 2003-07-08 KR KR1020117019614A patent/KR20110099808A/ko not_active Ceased
-
2005
- 2005-01-06 IL IL166178A patent/IL166178A/en unknown
-
2010
- 2010-08-02 JP JP2010173257A patent/JP2010285446A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1521762A2 (en) | 2005-04-13 |
| PL220778B1 (pl) | 2016-01-29 |
| WO2004005308A3 (en) | 2004-04-22 |
| AU2003251824A1 (en) | 2004-01-23 |
| AU2003251824B8 (en) | 2010-08-05 |
| CA2492446A1 (en) | 2004-01-15 |
| US20040267007A1 (en) | 2004-12-30 |
| RU2340621C2 (ru) | 2008-12-10 |
| EP1521762B1 (en) | 2014-03-12 |
| AU2003251824A2 (en) | 2004-01-23 |
| CN100497364C (zh) | 2009-06-10 |
| KR20050037460A (ko) | 2005-04-21 |
| CN1675231A (zh) | 2005-09-28 |
| BR0312656A (pt) | 2005-06-07 |
| IL166178A (en) | 2011-01-31 |
| MXPA05000407A (es) | 2005-04-19 |
| IL166178A0 (en) | 2006-01-15 |
| ES2456066T3 (es) | 2014-04-21 |
| US7232900B2 (en) | 2007-06-19 |
| JP2005536493A (ja) | 2005-12-02 |
| WO2004005308A2 (en) | 2004-01-15 |
| KR20110099808A (ko) | 2011-09-08 |
| AU2003251824B2 (en) | 2010-07-15 |
| JP2010285446A (ja) | 2010-12-24 |
| NZ537655A (en) | 2006-12-22 |
| RU2005102938A (ru) | 2005-08-10 |
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