PL374852A1 - Topliwy na gorąco układ-TTS do aplikowania rotigotyny - Google Patents
Topliwy na gorąco układ-TTS do aplikowania rotigotynyInfo
- Publication number
- PL374852A1 PL374852A1 PL03374852A PL37485203A PL374852A1 PL 374852 A1 PL374852 A1 PL 374852A1 PL 03374852 A PL03374852 A PL 03374852A PL 37485203 A PL37485203 A PL 37485203A PL 374852 A1 PL374852 A1 PL 374852A1
- Authority
- PL
- Poland
- Prior art keywords
- hot melt
- tts
- rotigotine
- adhesive layer
- melt tts
- Prior art date
Links
- 239000012943 hotmelt Substances 0.000 title abstract 2
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 title abstract 2
- 229960003179 rotigotine Drugs 0.000 title abstract 2
- 239000012790 adhesive layer Substances 0.000 abstract 3
- 239000004831 Hot glue Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Medicines Containing Plant Substances (AREA)
- External Artificial Organs (AREA)
Abstract
Wynalazek dotyczy poprzezskórnego układu terapeutycznego (TTS) zawierającego rotigotynonośną warstwę klejową, znamiennego tym, że ta warstwa klejowa zawiera przylepcowy klej topliwy na gorąco. To zgłoszenie patentowe nadto dotyczy zastosowania rotigotyny przy wytwarzaniu klejowej warstwy układu TTS w sposobie stapiania na gorąco.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10234673A DE10234673B4 (de) | 2002-07-30 | 2002-07-30 | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL374852A1 true PL374852A1 (pl) | 2005-11-14 |
| PL221308B1 PL221308B1 (pl) | 2016-03-31 |
Family
ID=30469194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL374852A PL221308B1 (pl) | 2002-07-30 | 2003-07-29 | Transdermalny system terapeutyczny (TTS ), sposób jego wytwarzania oraz zastosowanie rotygotyny |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9186335B2 (pl) |
| EP (2) | EP1492517B1 (pl) |
| JP (1) | JP4514608B2 (pl) |
| KR (1) | KR101041512B1 (pl) |
| CN (1) | CN100574755C (pl) |
| AT (1) | ATE324875T1 (pl) |
| AU (1) | AU2003269859B2 (pl) |
| BR (1) | BR0311437A (pl) |
| CA (1) | CA2494361C (pl) |
| CY (1) | CY1105138T1 (pl) |
| DE (2) | DE10234673B4 (pl) |
| DK (1) | DK1492517T3 (pl) |
| ES (1) | ES2263999T3 (pl) |
| IL (1) | IL166070A0 (pl) |
| MX (1) | MXPA04012150A (pl) |
| NO (1) | NO20050835L (pl) |
| PL (1) | PL221308B1 (pl) |
| PT (1) | PT1492517E (pl) |
| RU (1) | RU2304434C2 (pl) |
| WO (1) | WO2004012721A2 (pl) |
| ZA (1) | ZA200500457B (pl) |
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| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
| US8211462B2 (en) * | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
| DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
| US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
| US8246979B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
| DE10261696A1 (de) * | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| DE10361258A1 (de) * | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
| DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| DE602005020393D1 (de) | 2004-06-01 | 2010-05-20 | Hisamitsu Pharmaceutical Co | Adhäsive Pflaster |
| JP4986411B2 (ja) * | 2004-06-01 | 2012-07-25 | 久光製薬株式会社 | 貼付剤 |
| EP1796610A4 (en) * | 2004-09-29 | 2012-12-05 | Schwarz Pharma Inc | TRANSDERMAL THERAPEUTIC SYSTEM FOR PARKINSON'S DISEASE |
| DE102006026578B4 (de) | 2006-06-08 | 2009-01-08 | Lts Lohmann Therapie-Systeme Ag | Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
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| CN101147739B (zh) * | 2007-07-06 | 2010-12-08 | 北京康倍得医药技术开发有限公司 | 含罗替戈汀的组合物及其制药用途以及含该组合物的透皮贴剂 |
| PT2215072E (pt) * | 2007-11-28 | 2015-10-14 | Ucb Pharma Gmbh | Forma polimórfica de rotigotina |
| KR20110082142A (ko) * | 2008-10-06 | 2011-07-18 | 밀란 테크놀로지즈 인코포레이티드 | 비정질 로티고틴 경피 시스템 |
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| FI3257504T3 (fi) * | 2009-12-22 | 2024-07-31 | UCB Biopharma SRL | Polyvinyylipyrrolidoni ei-kidemäisessä muodossa olevan rotigotiinin kiinteän dispersion stabiloimiseksi |
| EP2544667B1 (en) * | 2010-03-09 | 2018-11-14 | Alkermes Pharma Ireland Limited | Alcohol resistant enteric pharmaceutical compositions |
| MY165003A (en) * | 2010-11-25 | 2018-02-28 | Shan Dong Luye Pharm Co Ltd | Compositions of rotigotine, derivatives thereof, or pharmaceutically acceptable salts of rotigotine or its derivative |
| WO2012084969A1 (en) | 2010-12-22 | 2012-06-28 | Hexal Ag | Adhesive composition containing rotigotine and transdermal therapeutic system comprising the adhesive composition |
| EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
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| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| DE102011119043A1 (de) | 2011-11-22 | 2013-05-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TDS) mit Rotigotin |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| WO2013075823A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising rotigotine and crystallization inhibitor |
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| WO2014007597A1 (ko) * | 2012-07-06 | 2014-01-09 | 에스케이케미칼(주) | 로티고틴 함유 경피흡수제제 |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
| KR101686987B1 (ko) * | 2013-05-30 | 2016-12-15 | 에스케이케미칼주식회사 | 로티고틴과 지방산 및 스티렌 점착제를 함유한 경피치료시스템 |
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| ES2694662T3 (es) | 2013-07-03 | 2018-12-26 | Lts Lohmann Therapie-Systeme Ag | Sistema terapéutico transdérmico con componente electrónico |
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| CN106456568B (zh) | 2014-05-20 | 2020-03-27 | Lts勒曼治疗系统股份公司 | 包含界面调节剂的经皮递送系统 |
| KR102364378B1 (ko) * | 2014-05-21 | 2022-02-16 | 에스케이케미칼 주식회사 | 안정성을 향상시킨 로티고틴 함유 경피흡수제제 |
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-
2002
- 2002-07-30 DE DE10234673A patent/DE10234673B4/de not_active Expired - Fee Related
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2003
- 2003-07-29 CA CA2494361A patent/CA2494361C/en not_active Expired - Fee Related
- 2003-07-29 CN CN03818378A patent/CN100574755C/zh not_active Expired - Fee Related
- 2003-07-29 DK DK03750403T patent/DK1492517T3/da active
- 2003-07-29 ES ES03750403T patent/ES2263999T3/es not_active Expired - Lifetime
- 2003-07-29 PT PT03750403T patent/PT1492517E/pt unknown
- 2003-07-29 MX MXPA04012150A patent/MXPA04012150A/es active IP Right Grant
- 2003-07-29 JP JP2004525355A patent/JP4514608B2/ja not_active Expired - Fee Related
- 2003-07-29 BR BR0311437-6A patent/BR0311437A/pt not_active Application Discontinuation
- 2003-07-29 US US10/523,908 patent/US9186335B2/en not_active Expired - Fee Related
- 2003-07-29 AT AT03750403T patent/ATE324875T1/de active
- 2003-07-29 EP EP03750403A patent/EP1492517B1/de not_active Expired - Lifetime
- 2003-07-29 EP EP06005770A patent/EP1669063A1/de not_active Withdrawn
- 2003-07-29 PL PL374852A patent/PL221308B1/pl unknown
- 2003-07-29 WO PCT/EP2003/008348 patent/WO2004012721A2/de not_active Ceased
- 2003-07-29 KR KR1020057001416A patent/KR101041512B1/ko not_active Expired - Fee Related
- 2003-07-29 AU AU2003269859A patent/AU2003269859B2/en not_active Ceased
- 2003-07-29 RU RU2005105684/15A patent/RU2304434C2/ru active
- 2003-07-29 DE DE50303201T patent/DE50303201D1/de not_active Expired - Lifetime
- 2003-07-29 IL IL16607003A patent/IL166070A0/xx unknown
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2005
- 2005-01-18 ZA ZA2005/00457A patent/ZA200500457B/en unknown
- 2005-02-16 NO NO20050835A patent/NO20050835L/no not_active Application Discontinuation
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2006
- 2006-07-28 CY CY20061101048T patent/CY1105138T1/el unknown
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