PL375067A1 - Sposób otrzymywania żywotnych komórek wątroby obejmujących komórki macierzyste/progenitorowe hepatocytów - Google Patents

Sposób otrzymywania żywotnych komórek wątroby obejmujących komórki macierzyste/progenitorowe hepatocytów

Info

Publication number
PL375067A1
PL375067A1 PL03375067A PL37506703A PL375067A1 PL 375067 A1 PL375067 A1 PL 375067A1 PL 03375067 A PL03375067 A PL 03375067A PL 37506703 A PL37506703 A PL 37506703A PL 375067 A1 PL375067 A1 PL 375067A1
Authority
PL
Poland
Prior art keywords
obtaining viable
progenitor cells
including hepatocyte
hepatocyte stem
viable liver
Prior art date
Application number
PL03375067A
Other languages
English (en)
Inventor
John W. Ludlow
Mark E. Furth
Andrew T. Bruce
Lola M. Reid
Robert L.Jr. Susick
Original Assignee
Vesta Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vesta Therapeutics, Inc. filed Critical Vesta Therapeutics, Inc.
Publication of PL375067A1 publication Critical patent/PL375067A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
PL03375067A 2002-07-19 2003-07-17 Sposób otrzymywania żywotnych komórek wątroby obejmujących komórki macierzyste/progenitorowe hepatocytów PL375067A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39662902P 2002-07-19 2002-07-19

Publications (1)

Publication Number Publication Date
PL375067A1 true PL375067A1 (pl) 2005-11-14

Family

ID=30770927

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03375067A PL375067A1 (pl) 2002-07-19 2003-07-17 Sposób otrzymywania żywotnych komórek wątroby obejmujących komórki macierzyste/progenitorowe hepatocytów

Country Status (12)

Country Link
US (2) US20040110289A1 (pl)
EP (1) EP1576117A4 (pl)
JP (1) JP2006506971A (pl)
CN (1) CN100441682C (pl)
AU (1) AU2003251954B2 (pl)
CA (1) CA2492905A1 (pl)
IL (1) IL166364A0 (pl)
MX (1) MXPA05000858A (pl)
PL (1) PL375067A1 (pl)
RU (1) RU2346981C2 (pl)
SG (1) SG155053A1 (pl)
WO (1) WO2004009766A2 (pl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR044743A1 (es) * 2002-09-26 2005-10-05 Nihon Nohyaku Co Ltd Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
US20060121512A1 (en) * 2004-12-02 2006-06-08 Organ Recovery Systems, Inc. Biological pathways in progenitor cells
US7604929B2 (en) 2005-04-21 2009-10-20 In Vitro Technologies, Inc. Cellular compositions and methods for their preparation
US20070148141A1 (en) * 2005-12-22 2007-06-28 Vesta Therapeutics Inc. Method of using hepatic progenitors in treating liver dysfunction
ITNA20060017A1 (it) * 2006-02-20 2007-08-21 Aquino Riccardo D Tecnica di prelievo e selezione di un una popolazione di cellule staminali di tipo embrionale da tessuti follicolari peridentari di uomo adulto.
US20070238137A1 (en) * 2006-04-07 2007-10-11 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Constitutively resistant cancer stem cells in diagnosis
GB2440908A (en) * 2006-05-25 2008-02-20 Intercytex Ltd Tissue Repair and Augmentation
WO2008137280A1 (en) * 2007-05-03 2008-11-13 Fox Chase Cancer Center Compositions and methods for altering pancreas or liver function
KR20240052847A (ko) * 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
GB0822246D0 (en) * 2008-12-05 2009-01-14 Reneuron Ltd Composition
US20100329986A1 (en) * 2009-01-06 2010-12-30 Greenbaum Linda E Adult Hepatic Progenitor Cells and Methods of Use Thereof
GB0902034D0 (en) 2009-02-06 2009-03-11 Reneuron Ltd Method
US20100272816A1 (en) 2009-04-27 2010-10-28 Wolfgang Rudinger Microcapsules comprising liver cells and erythropoietin, methods for preparing said microcapsules and methods for treating a patient comprising applying said microcapsules to the patient
WO2011123665A1 (en) * 2010-03-31 2011-10-06 Biolife Solutions, Inc. Methods and compositions for the treatment of burns and wounds
JP5841322B2 (ja) 2010-04-22 2016-01-13 オレゴン ヘルス アンド サイエンス ユニバーシティ フマリルアセト酢酸ヒドロラーゼ（ｆａｈ）欠損性ブタおよびその使用
JP5771917B2 (ja) * 2010-08-04 2015-09-02 公益財団法人ヒューマンサイエンス振興財団 単核球分離管及び単核球分離システム
DE102010034330B4 (de) * 2010-08-14 2013-10-31 Cytonet Gmbh & Co. Kg Verfahren zur Herstellung desinfizierter humaner Zellsuspensionen
EP2747551B1 (en) 2011-08-26 2020-02-12 Yecuris Corporation Fumarylacetoacetate hydrolase (fah)-deficient and immunodeficient rats and uses thereof
RU2477752C1 (ru) * 2012-02-17 2013-03-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт фармакологии" Сибирского отделения Российской академии медицинских наук ФГБУ "НИИ фармакологии" СО РАМН Способ стимуляции дифференцировки стволовых клеток печени in vitro в тканеспецифичном направлении
CN103361299B (zh) * 2012-04-01 2015-09-30 张文炜 分离干细胞的方法和试剂盒
CN102763642B (zh) * 2012-08-14 2014-04-02 郑州赛英科干细胞技术有限公司 一种冷冻保护液以及冷冻保存人胎盘羊膜和绒毛膜的方法
US20150218521A1 (en) * 2012-09-28 2015-08-06 Swiss Stem Cell Foundation High-safety process for the preparation of purified stem cell fractions
CN103210903B (zh) * 2013-05-03 2014-10-29 新乡医学院 一种用于保存cik细胞的冻存液及其应用
WO2016200980A1 (en) * 2015-06-08 2016-12-15 The Regents Of The University Of Colorado A Body Corporate Apparatus and methods for freezing, storing, and thawing biological materials
WO2017070007A2 (en) 2015-10-15 2017-04-27 Wake Forest University Health Sciences Methods of producing in vitro liver constructs and uses thereof
JP7174408B2 (ja) * 2016-02-10 2022-11-17 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ 肝線維症のモデル系ならびにその作製および使用方法
CN108300687A (zh) * 2017-12-29 2018-07-20 广西医科大学第附属医院 一种基于肾小管上皮细胞培养造影剂损伤模型的方法
CN108165521A (zh) * 2017-12-29 2018-06-15 广西医科大学第附属医院 一种接近cin患者血清hmgb-1含量的体外细胞培养方法
CN108360074B (zh) * 2018-02-11 2022-01-18 奥明（杭州）基因科技有限公司 一种组织淋巴细胞转座酶可接近性染色质分析的建库方法
IL324627A (en) 2019-04-11 2026-01-01 Univ Pittsburgh Commonwealth Sys Higher Education A minimally invasive cell transplantation procedure to induce the development of organ formation in an animal body.
CN111394391B (zh) * 2019-07-11 2022-12-06 上海赛立维生物科技有限公司 肝祖细胞样细胞库的构建方法及其制备的细胞株与应用
CN110643571B (zh) * 2019-10-22 2021-07-27 康妍葆(北京)干细胞科技有限公司 人角蛋白6a在干细胞培养中的应用及产品
JP2024515805A (ja) * 2021-04-27 2024-04-10 アヴィータ・メディカル・インコーポレイテッド 新たに脱凝集された組織に由来する再生生物活性懸濁液および臨床治療における使用方法
WO2023228873A1 (ja) * 2022-05-24 2023-11-30 国立研究開発法人国立成育医療研究センター 肝細胞の製造方法、肝細胞の接着性改善剤、および肝細胞
US12570949B2 (en) 2022-12-27 2026-03-10 AVITA Medical Americas, LLC Systems and devices for wound therapy and related methods of use
DE202023002794U1 (de) 2022-12-27 2024-07-15 AVITA Medical Americas, LLC Kassette zur Herstellung einer regenerativen epidermalen Suspension
CN116286605A (zh) * 2023-03-29 2023-06-23 复旦大学附属中山医院 一种制备纤维化肝脏单细胞悬液的试剂、试剂盒及方法
USD1112812S1 (en) 2023-12-22 2026-02-10 AVITA Medical Americas, LLC Tissue processing cartridge

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298002A (en) * 1979-09-10 1981-11-03 National Patent Development Corporation Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation
JPS59500340A (ja) * 1982-03-08 1984-03-01 モトロ−ラ・インコ−ポレ−テツド 集積回路のリ−ドフレ−ム
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5266480A (en) * 1986-04-18 1993-11-30 Advanced Tissue Sciences, Inc. Three-dimensional skin culture system
US5149543A (en) * 1990-10-05 1992-09-22 Massachusetts Institute Of Technology Ionically cross-linked polymeric microcapsules
ES2157225T3 (es) * 1992-10-09 2001-08-16 Advanced Tissue Sciences Inc Celulas hepaticas de reserva.
CA2146735C (en) * 1994-04-11 2007-02-20 Chise Tateno Liver parenchymal cells having clonal growth ability, method for obtaining same, method for subculturing same, and subculturing system of primary hepatocytes
US5785965A (en) * 1996-05-15 1998-07-28 The Board Of Trustees Of The Leland Stanford Junior Univ. VEGF gene transfer into endothelial cells for vascular prosthesis
US6544972B1 (en) * 1997-09-25 2003-04-08 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
US6140123A (en) * 1998-10-07 2000-10-31 Cedars-Sinai Medical Center Method for conditioning and cryopreserving cells
RU2153344C1 (ru) * 1999-09-13 2000-07-27 Тимербулатов Виль Мамилович Способ трансплантации эмбриональных печеночных клеток в эксперименте
WO2001053462A1 (en) * 2000-01-19 2001-07-26 University Of North Carolina At Chapel Hill Liver tissue source
US20020042335A1 (en) * 2000-04-18 2002-04-11 Anderson Norman G. Method and apparatus for making density gradients

Also Published As

Publication number Publication date
RU2005104557A (ru) 2005-09-10
IL166364A0 (en) 2006-01-16
MXPA05000858A (es) 2005-10-19
JP2006506971A (ja) 2006-03-02
US20040110289A1 (en) 2004-06-10
SG155053A1 (en) 2009-09-30
WO2004009766A2 (en) 2004-01-29
CA2492905A1 (en) 2004-01-29
AU2003251954B2 (en) 2008-06-26
US20100112689A1 (en) 2010-05-06
CN100441682C (zh) 2008-12-10
CN1728946A (zh) 2006-02-01
EP1576117A2 (en) 2005-09-21
RU2346981C2 (ru) 2009-02-20
AU2003251954A1 (en) 2004-02-09
WO2004009766A3 (en) 2005-08-11
EP1576117A4 (en) 2006-02-01

Similar Documents

Publication Publication Date Title
PL375067A1 (pl) Sposób otrzymywania żywotnych komórek wątroby obejmujących komórki macierzyste/progenitorowe hepatocytów
CY2019038I1 (el) Μεθοδοι για την κινητοποιηση κυτταρων προγεννητορων/βλαστοκυτταρων
EP1576117A3 (en) Method of obtaining viable human liver cells, including hepatic stem/progenitor cells
DK1918364T3 (da) Fremgangsmåde til rekloning af produktionsceller
DK1718675T3 (da) Fremgangsmåde til at tilvejebringe en oprenset virussikker antistoftilberedning
DK1838874T3 (da) Fremgangsmåder til regulering af stamceller
DK2959774T3 (da) Fremgangsmåde til kryokonservering af sædceller
DK2213724T3 (da) Medium frit for dyreprotein til dyrkning af celler
DK1748077T3 (da) Fremgangsmåde til fremstilling af protein
IL189882A0 (en) Method of deriving mesenchymal stem cells
DE602004010273D1 (de) Amplifikationsmethode
DK1856374T3 (da) Sammensætning og fremgangsmåde til fremstilling af et støttemiddel
DK1974017T4 (da) Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler
DK2479259T3 (da) Multi-kryokonserverede hepatocytter og fremgangsmåder til fremstillilng deraf
DK1745136T3 (da) Fremgangsmåde til enzymatisk fremstilling af (S)-3-cyano-5-methylhexansyre
DK1907628T3 (da) Kunstgræsstruktur og fremgangsmåde til fremstilling deraf
DK2573166T3 (da) Fremgangsmåder til fremstilling af T-celler til celleterapi
DE602005026148D1 (de) Doppelbündiger bördelzapfen
DK1542714T3 (da) Fremgangsmåder til forøgelse af produktion af blodplader og hæmatopoietiske stamceller
IS8646A (is) Aðferð til að framleiða spendýrafrumur
FR2873872B1 (fr) Amplificateur audio classe ad
EP1563058A4 (en) Haemangioblasts-Progenitor Cells
DK1795586T3 (da) Fremgangsmåde til svampedyrkning
DK1727792T3 (da) Fremgangsmåde til fremstilling af semicarbazoner
AT7072U3 (de) Umbauverfahren

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)