PL376803A1 - Nowe pochodne tetracykliczne zawierające heteroatomy, jako selektywne modulatory receptora estrogenowego - Google Patents
Nowe pochodne tetracykliczne zawierające heteroatomy, jako selektywne modulatory receptora estrogenowegoInfo
- Publication number
- PL376803A1 PL376803A1 PL376803A PL37680303A PL376803A1 PL 376803 A1 PL376803 A1 PL 376803A1 PL 376803 A PL376803 A PL 376803A PL 37680303 A PL37680303 A PL 37680303A PL 376803 A1 PL376803 A1 PL 376803A1
- Authority
- PL
- Poland
- Prior art keywords
- estrogen receptor
- receptor modulators
- selective estrogen
- heteroatom containing
- tetracyclic derivatives
- Prior art date
Links
- 125000005842 heteroatom Chemical group 0.000 title 1
- 239000000333 selective estrogen receptor modulator Substances 0.000 title 1
- 229940095743 selective estrogen receptor modulator Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/307,735 US7329654B2 (en) | 2001-12-19 | 2002-12-02 | Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL376803A1 true PL376803A1 (pl) | 2006-01-09 |
Family
ID=32467796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL376803A PL376803A1 (pl) | 2002-12-02 | 2003-11-21 | Nowe pochodne tetracykliczne zawierające heteroatomy, jako selektywne modulatory receptora estrogenowego |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7329654B2 (pl) |
| EP (1) | EP1569939A1 (pl) |
| JP (1) | JP2006514941A (pl) |
| CN (2) | CN1745085A (pl) |
| AU (1) | AU2003295822A1 (pl) |
| BR (1) | BR0316843A (pl) |
| CA (1) | CA2505857A1 (pl) |
| MX (1) | MXPA05005897A (pl) |
| NZ (1) | NZ539914A (pl) |
| PL (1) | PL376803A1 (pl) |
| RU (1) | RU2331645C2 (pl) |
| WO (1) | WO2004050660A1 (pl) |
| ZA (1) | ZA200505324B (pl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2587669A1 (en) * | 2004-11-18 | 2006-05-26 | Janssen Pharmaceutica N.V. | Novel 2h-chromene derivatives as selective estrogen receptor modulators |
| EP1846386A2 (en) * | 2005-01-21 | 2007-10-24 | Janssen Pharmaceutica N.V. | Novel coumarin derivatives as ion channel openers |
| US8633178B2 (en) | 2011-11-23 | 2014-01-21 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| WO2015089810A1 (en) | 2013-12-20 | 2015-06-25 | Merck Sharp & Dohme Corp. | Fused tetracyclic heterocyclic compounds and methods of use thereof for the treatment of viral diseases |
| EP3145489A1 (en) | 2014-05-22 | 2017-03-29 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| CN112424205B (zh) * | 2018-07-12 | 2023-10-31 | 伊莱利利公司 | 选择性的雌激素受体降解剂 |
| TWI702219B (zh) * | 2018-07-12 | 2020-08-21 | 美商美國禮來大藥廠 | 選擇性雌激素受體降解劑 |
| CN111039910A (zh) * | 2019-12-31 | 2020-04-21 | 云南大学 | 一种光引发的合成3-芳基黄酮或香豆素类化合物的方法及应用 |
| AU2021206684B2 (en) | 2020-01-10 | 2024-01-18 | Immuneering Corporation | MEK inhibitors and therapeutic uses thereof |
| US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL124481C (pl) | 1964-11-04 | |||
| US5686465A (en) | 1988-10-31 | 1997-11-11 | Endorecherche Inc. | Sex steroid activity inhibitors |
| US5395842A (en) | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| IN173337B (pl) | 1989-11-08 | 1994-04-02 | Council Scient Ind Res | |
| EP0470310B1 (en) | 1990-08-09 | 1995-11-29 | Council of Scientific and Industrial Research | Novel benzopyrans and process for their production |
| US6060503A (en) | 1991-12-02 | 2000-05-09 | Endorecherche, Inc. | Benzopyran-containing compounds and method for their use |
| RU2084455C1 (ru) * | 1995-05-18 | 1997-07-20 | Научно-исследовательский институт физической и органической химии Ростовского государственного университета | Дибензо(в,е) пирано(3,2-в)-1-бензопирилиевые соли и способ их получения |
| US5726186A (en) * | 1995-09-08 | 1998-03-10 | Eli Lilly And Company | Pentacyclic compounds, intermediates, processes, compositions, and methods |
| CA2214196A1 (en) | 1996-09-26 | 1998-03-26 | Eli Lilly And Company | Benzo[b]indeno[2,1-d]thiophene compounds, intermediates, processes, compositions and methods |
| US6153768A (en) | 1996-12-13 | 2000-11-28 | C & C Research Laboratories | Benzopyran derivatives |
| EP1467998B1 (en) | 2001-12-19 | 2006-03-29 | Ortho-Mcneil Pharmaceutical, Inc. | Tetracyclic heterocompounds as estrogen receptor modulators |
-
2002
- 2002-12-02 US US10/307,735 patent/US7329654B2/en not_active Expired - Fee Related
-
2003
- 2003-11-21 WO PCT/US2003/037419 patent/WO2004050660A1/en not_active Ceased
- 2003-11-21 CA CA002505857A patent/CA2505857A1/en not_active Abandoned
- 2003-11-21 MX MXPA05005897A patent/MXPA05005897A/es active IP Right Grant
- 2003-11-21 JP JP2004557261A patent/JP2006514941A/ja not_active Withdrawn
- 2003-11-21 RU RU2005116845/04A patent/RU2331645C2/ru active
- 2003-11-21 EP EP03787032A patent/EP1569939A1/en not_active Ceased
- 2003-11-21 AU AU2003295822A patent/AU2003295822A1/en not_active Abandoned
- 2003-11-21 NZ NZ539914A patent/NZ539914A/en unknown
- 2003-11-21 PL PL376803A patent/PL376803A1/pl unknown
- 2003-11-21 CN CNA2003801093959A patent/CN1745085A/zh active Pending
- 2003-11-21 CN CNA2008101901315A patent/CN101450950A/zh active Pending
- 2003-11-21 BR BR0316843-3A patent/BR0316843A/pt not_active IP Right Cessation
-
2005
- 2005-06-30 ZA ZA200505324A patent/ZA200505324B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ539914A (en) | 2008-03-28 |
| JP2006514941A (ja) | 2006-05-18 |
| CN101450950A (zh) | 2009-06-10 |
| BR0316843A (pt) | 2005-11-01 |
| CN1745085A (zh) | 2006-03-08 |
| ZA200505324B (en) | 2006-09-27 |
| EP1569939A1 (en) | 2005-09-07 |
| RU2005116845A (ru) | 2006-01-20 |
| WO2004050660A1 (en) | 2004-06-17 |
| US7329654B2 (en) | 2008-02-12 |
| MXPA05005897A (es) | 2006-02-08 |
| AU2003295822A1 (en) | 2004-06-23 |
| CA2505857A1 (en) | 2004-06-17 |
| RU2331645C2 (ru) | 2008-08-20 |
| US20030216463A1 (en) | 2003-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DISC | Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications) |