PL377227A1 - Postawione pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych - Google Patents

Postawione pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych

Info

Publication number: PL377227A1
Authority: PL; Poland
Prior art keywords: pyrimidin; medicaments; production; dion derivatives; hexahydropyrazino
Prior art date: 2003-02-13

Application number

PL377227A

Other languages

English (en)

Inventor

Stefanie Flohr

Siegfried Stengelin

Matthias Gossel

Thomas Klabunde

James Spoonamore

Pavel Safar

Martin Smrcina

Original Assignee

Sanofi-Aventis Deutschland Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-13

Filing date

2004-01-29

Publication date

2006-01-23

2003-02-13 Priority claimed from DE10305885A external-priority patent/DE10305885A1/de

2003-10-24 Priority claimed from DE10349672A external-priority patent/DE10349672A1/de

2004-01-29 Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh

2006-01-23 Publication of PL377227A1 publication Critical patent/PL377227A1/pl

Links

CYCRMTFRHLQFIV-UHFFFAOYSA-N 2,3,6,8,9,9a-hexahydro-1h-pyrazino[1,2-a]pyrimidine-4,7-dione Chemical class N1CCC(=O)N2C1CNC(=O)C2 CYCRMTFRHLQFIV-UHFFFAOYSA-N 0.000 title 1
239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Dermatology (AREA)
Hematology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Pregnancy & Childbirth (AREA)
Addiction (AREA)
Emergency Medicine (AREA)
Communicable Diseases (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Gynecology & Obstetrics (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)

PL377227A 2003-02-13 2004-01-29 Postawione pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych PL377227A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10305885A DE10305885A1 (de)	2003-02-13	2003-02-13	Substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE10349672A DE10349672A1 (de)	2003-10-24	2003-10-24	Substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number	Publication Date
PL377227A1 true PL377227A1 (pl)	2006-01-23

Family

ID=32870334

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL377227A PL377227A1 (pl)	2003-02-13	2004-01-29	Postawione pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych

Country Status (21)

Country	Link
EP (1)	EP1599480B1 (pl)
JP (1)	JP2006517550A (pl)
KR (1)	KR20050111588A (pl)
AR (1)	AR043155A1 (pl)
AT (1)	ATE472548T1 (pl)
AU (1)	AU2004212042A1 (pl)
BR (1)	BRPI0407507A (pl)
CA (1)	CA2515735A1 (pl)
CO (1)	CO5690597A2 (pl)
DE (1)	DE502004011328D1 (pl)
HR (1)	HRP20050712A2 (pl)
MA (1)	MA27654A1 (pl)
MX (1)	MXPA05007516A (pl)
MY (1)	MY135902A (pl)
NO (1)	NO20054085L (pl)
PE (1)	PE20050192A1 (pl)
PL (1)	PL377227A1 (pl)
RS (1)	RS20050564A (pl)
RU (1)	RU2005128497A (pl)
TW (1)	TW200508235A (pl)
WO (1)	WO2004072076A1 (pl)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040072831A1 (en) *	2001-10-12	2004-04-15	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
US7576084B2 (en)	2001-10-12	2009-08-18	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
US7671054B1 (en)	2001-10-12	2010-03-02	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
US7566711B2 (en)	2001-10-12	2009-07-28	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
US8080657B2 (en)	2001-10-12	2011-12-20	Choongwae Pharma Corporation	Compounds of reverse turn mimetics and the use thereof
US7232822B2 (en)	2001-10-12	2007-06-19	Choongwae Pharma Corporation	Reverse-turn mimetics and method relating thereto
WO2004072077A1 (de) *	2003-02-13	2004-08-26	Aventis Pharma Deutshland Gmbh	STICKSTOFF SUBSTITUIERTE HEXAHYDRO-PYRAZINO[1,2-a]PYRIMIDIN-4,7-DIONDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL
DE102004042441A1 (de) *	2004-08-31	2006-04-06	Sanofi-Aventis Deutschland Gmbh	Mit Aminosäuren substituierte Hexahydro-pyrazino(1,2-a)pyrimidin-4,7-dionderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
MX2007016508A (es)	2005-06-30	2008-03-04	Prosidion Ltd	Agonistas del receptor acoplado a la proteina g.
WO2007056593A2 (en) *	2005-11-08	2007-05-18	Choongwae Pharma Corporation	α-HELIX MIMETICS AND METHOD RELATING TO THE TREATMENT OF CANCER STEM CELLS
US20080009500A1 (en) *	2005-11-08	2008-01-10	Michael Kahn	Alpha-helix mimetics and methods relating to the treatment of fibrotic disorders
EP2061767B1 (de)	2006-08-08	2014-12-17	Sanofi	Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
US20100048632A1 (en)	2007-01-04	2010-02-25	Matthew Colin Thor Fyfe	Piperidine GPCR Agonists
PE20081849A1 (es)	2007-01-04	2009-01-26	Prosidion Ltd	Derivados de piperidin-4-il-propoxi-benzamida como agonistas de gpcr
GB0700122D0 (en)	2007-01-04	2007-02-14	Prosidion Ltd	GPCR agonists
PE20081659A1 (es)	2007-01-04	2008-10-24	Prosidion Ltd	Agonistas de gpcr
US20100048625A1 (en)	2007-01-04	2010-02-25	Matthew Colin Thor Fyfe	Piperidine gpcr agonists
EP2025674A1 (de)	2007-08-15	2009-02-18	sanofi-aventis	Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
GB0720390D0 (en)	2007-10-18	2007-11-28	Prosidion Ltd	G-Protein coupled receptor agonists
GB0720389D0 (en)	2007-10-18	2008-11-12	Prosidion Ltd	G-Protein Coupled Receptor Agonists
UY31968A (es)	2008-07-09	2010-01-29	Sanofi Aventis	Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
WO2010068601A1 (en)	2008-12-08	2010-06-17	Sanofi-Aventis	A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
KR20120060207A (ko)	2009-08-26	2012-06-11	사노피	신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도
EP2766349B1 (de)	2011-03-08	2016-06-01	Sanofi	Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8895547B2 (en)	2011-03-08	2014-11-25	Sanofi	Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
EP2683699B1 (de)	2011-03-08	2015-06-24	Sanofi	Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
WO2012120051A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
WO2012120058A1 (de)	2011-03-08	2012-09-13	Sanofi	Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683702B1 (de)	2011-03-08	2014-12-24	Sanofi	Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828994B2 (en)	2011-03-08	2014-09-09	Sanofi	Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120056A1 (de)	2011-03-08	2012-09-13	Sanofi	Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2683704B1 (de)	2011-03-08	2014-12-17	Sanofi	Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP4698551A1 (en) *	2023-04-21	2026-02-25	The University of Hong Kong	Novel small molecule agonists of insulin receptor (insr) as anti-diabetes drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6184223B1 (en) *	1995-10-27	2001-02-06	Molecumetics Ltd.	Reverse-turn mimetics and methods relating thereto
WO1998058947A1 (en) *	1997-06-25	1998-12-30	Pfizer Inc.	Dipeptide derivatives as growth hormone secretagogues
US6294525B1 (en) *	1999-09-01	2001-09-25	Molecumetics Ltd.	Reverse-turn mimetics and methods relating thereto
WO2004072077A1 (de) *	2003-02-13	2004-08-26	Aventis Pharma Deutshland Gmbh	STICKSTOFF SUBSTITUIERTE HEXAHYDRO-PYRAZINO[1,2-a]PYRIMIDIN-4,7-DIONDERIVATE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL

2004
- 2004-01-29 RU RU2005128497/04A patent/RU2005128497A/ru not_active Application Discontinuation
- 2004-01-29 RS YUP-2005/0564A patent/RS20050564A/sr unknown
- 2004-01-29 BR BRPI0407507-2A patent/BRPI0407507A/pt not_active IP Right Cessation
- 2004-01-29 PL PL377227A patent/PL377227A1/pl not_active Application Discontinuation
- 2004-01-29 CA CA002515735A patent/CA2515735A1/en not_active Abandoned
- 2004-01-29 MX MXPA05007516A patent/MXPA05007516A/es not_active Application Discontinuation
- 2004-01-29 EP EP04706170A patent/EP1599480B1/de not_active Expired - Lifetime
- 2004-01-29 DE DE502004011328T patent/DE502004011328D1/de not_active Expired - Lifetime
- 2004-01-29 HR HR20050712A patent/HRP20050712A2/xx not_active Application Discontinuation
- 2004-01-29 AT AT04706170T patent/ATE472548T1/de not_active IP Right Cessation
- 2004-01-29 KR KR1020057014859A patent/KR20050111588A/ko not_active Withdrawn
- 2004-01-29 WO PCT/EP2004/000769 patent/WO2004072076A1/de not_active Ceased
- 2004-01-29 JP JP2006501649A patent/JP2006517550A/ja active Pending
- 2004-01-29 AU AU2004212042A patent/AU2004212042A1/en not_active Abandoned
- 2004-02-09 PE PE2004000147A patent/PE20050192A1/es not_active Application Discontinuation
- 2004-02-11 AR ARP040100427A patent/AR043155A1/es unknown
- 2004-02-11 TW TW093103121A patent/TW200508235A/zh unknown
- 2004-02-12 MY MYPI20040456A patent/MY135902A/en unknown
2005
- 2005-08-11 CO CO05079789A patent/CO5690597A2/es not_active Application Discontinuation
- 2005-08-11 MA MA28428A patent/MA27654A1/fr unknown
- 2005-09-02 NO NO20054085A patent/NO20054085L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20050111588A (ko)	2005-11-25
MXPA05007516A (es)	2006-01-27
DE502004011328D1 (de)	2010-08-12
EP1599480B1 (de)	2010-06-30
EP1599480A1 (de)	2005-11-30
JP2006517550A (ja)	2006-07-27
WO2004072076A1 (de)	2004-08-26
PE20050192A1 (es)	2005-04-01
AU2004212042A1 (en)	2004-08-26
AR043155A1 (es)	2005-07-20
BRPI0407507A (pt)	2006-02-14
CO5690597A2 (es)	2006-10-31
MA27654A1 (fr)	2005-12-01
HRP20050712A2 (en)	2006-09-30
RU2005128497A (ru)	2006-01-27
ATE472548T1 (de)	2010-07-15
CA2515735A1 (en)	2004-08-26
MY135902A (en)	2008-07-31
TW200508235A (en)	2005-03-01
RS20050564A (sr)	2007-09-21
NO20054085L (no)	2005-09-02

Legal Events

Date	Code	Title	Description
2013-04-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL377227A1 (pl)	2006-01-23	Postawione pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych
PL377660A1 (pl)	2006-02-06	Podstawione przy azocie pochodne heksahydropirazyno [1,2-a] pirymidyno-4,7-dionu, sposób ich wytwarzania i ich zastosowanie jako środków leczniczych
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