PL3781562T3 - Sposób wytwarzania modulatorów p300 i/albo cbp - Google Patents

Sposób wytwarzania modulatorów p300 i/albo cbp

Info

Publication number
PL3781562T3
PL3781562T3 PL19719605.8T PL19719605T PL3781562T3 PL 3781562 T3 PL3781562 T3 PL 3781562T3 PL 19719605 T PL19719605 T PL 19719605T PL 3781562 T3 PL3781562 T3 PL 3781562T3
Authority
PL
Poland
Prior art keywords
cbp
modulators
preparing
preparing modulators
Prior art date
Application number
PL19719605.8T
Other languages
English (en)
Inventor
Paul Baguley
Donald Alan GILBERT
Gareth HARBOTTLE
Colin Lindley
John Paul Madeley
James Vaughan Morey
David Michel Adrien Taddei
Jonathan TREVORROW
David Wood
Original Assignee
Cellcentric Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellcentric Ltd filed Critical Cellcentric Ltd
Publication of PL3781562T3 publication Critical patent/PL3781562T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Crushing And Grinding (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
PL19719605.8T 2018-04-18 2019-04-18 Sposób wytwarzania modulatorów p300 i/albo cbp PL3781562T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1806320.6A GB201806320D0 (en) 2018-04-18 2018-04-18 Process
PCT/GB2019/051110 WO2019202332A1 (en) 2018-04-18 2019-04-18 Process for preparing modulators of p300 and/or cbp

Publications (1)

Publication Number Publication Date
PL3781562T3 true PL3781562T3 (pl) 2025-03-17

Family

ID=62203477

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19719605.8T PL3781562T3 (pl) 2018-04-18 2019-04-18 Sposób wytwarzania modulatorów p300 i/albo cbp

Country Status (27)

Country Link
US (1) US11453662B2 (pl)
EP (1) EP3781562B1 (pl)
JP (1) JP7371006B2 (pl)
KR (1) KR102792479B1 (pl)
CN (2) CN112351982B (pl)
AU (1) AU2019256788B2 (pl)
BR (1) BR112020021224A2 (pl)
CA (3) CA3281595A1 (pl)
DK (1) DK3781562T3 (pl)
EA (1) EA202092113A1 (pl)
ES (1) ES3008927T3 (pl)
FI (1) FI3781562T3 (pl)
GB (1) GB201806320D0 (pl)
HR (1) HRP20241720T1 (pl)
HU (1) HUE069983T2 (pl)
IL (1) IL278015B2 (pl)
LT (1) LT3781562T (pl)
MX (1) MX2020010817A (pl)
NZ (1) NZ768679A (pl)
PL (1) PL3781562T3 (pl)
PT (1) PT3781562T (pl)
RS (1) RS66587B1 (pl)
SG (1) SG11202009919WA (pl)
SI (1) SI3781562T1 (pl)
SM (1) SMT202500039T1 (pl)
WO (1) WO2019202332A1 (pl)
ZA (1) ZA202006441B (pl)

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CN112574189B (zh) * 2019-09-27 2024-05-31 海创药业股份有限公司 一种ep300/cbp抑制剂
KR20230028798A (ko) 2020-06-25 2023-03-02 톨레모 테라퓨틱스 아게 암 치료를 위한 CBP/p300 브로모도메인 억제제 및 KRAS 억제제의 조합물
BR112022025911A2 (pt) 2020-06-25 2023-01-10 Tolremo Therapeutics Ag Combinação de um inibidor de bromodomínio de cbp/p300 e um inibidor de egfr para uso no tratamento de um cpcnp com egfr mutante
KR102892940B1 (ko) 2021-01-11 2025-11-27 주식회사 엘지에너지솔루션 전지 모듈 및 이를 포함하는 전지팩
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Also Published As

Publication number Publication date
WO2019202332A1 (en) 2019-10-24
KR102792479B1 (ko) 2025-04-08
EA202092113A1 (ru) 2021-03-30
CA3293782A1 (en) 2026-03-02
IL278015A (en) 2020-11-30
IL278015B2 (en) 2023-08-01
PT3781562T (pt) 2025-02-11
NZ768679A (en) 2026-03-27
DK3781562T3 (da) 2024-12-02
FI3781562T3 (fi) 2025-02-04
RS66587B1 (sr) 2025-04-30
CN112351982A (zh) 2021-02-09
MX2020010817A (es) 2020-10-28
IL278015B1 (en) 2023-04-01
JP7371006B2 (ja) 2023-10-30
CA3281595A1 (en) 2025-11-29
CN118388475A (zh) 2024-07-26
JP2021521237A (ja) 2021-08-26
EP3781562A1 (en) 2021-02-24
GB201806320D0 (en) 2018-05-30
HRP20241720T1 (hr) 2025-04-25
US20210163463A1 (en) 2021-06-03
SMT202500039T1 (it) 2025-03-12
KR20210003175A (ko) 2021-01-11
LT3781562T (lt) 2025-03-25
US11453662B2 (en) 2022-09-27
BR112020021224A2 (pt) 2021-02-23
HUE069983T2 (hu) 2025-04-28
SI3781562T1 (sl) 2025-04-30
CN112351982B (zh) 2024-10-18
EP3781562B1 (en) 2024-11-20
AU2019256788B2 (en) 2022-10-20
SG11202009919WA (en) 2020-11-27
CA3096441A1 (en) 2019-10-24
AU2019256788A1 (en) 2020-10-29
ZA202006441B (en) 2023-01-25
ES3008927T3 (en) 2025-03-25

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