PL378918A1 - Związki typu eterów aminocykloheksylowych i ich zastosowania - Google Patents

Związki typu eterów aminocykloheksylowych i ich zastosowania

Info

Publication number
PL378918A1
PL378918A1 PL378918A PL37891803A PL378918A1 PL 378918 A1 PL378918 A1 PL 378918A1 PL 378918 A PL378918 A PL 378918A PL 37891803 A PL37891803 A PL 37891803A PL 378918 A1 PL378918 A1 PL 378918A1
Authority
PL
Poland
Prior art keywords
ether compounds
aminocyclohexyl ether
compounds
compositions
present
Prior art date
Application number
PL378918A
Other languages
English (en)
Other versions
PL227937B1 (pl
Inventor
Gregory N. Beatch
Lewis Siu Leung Choi
Grace Jung
Yuzhong Liu
Bertrand Plouvier
Richard Wall
Jeff Zhu
Alexander Zolotoy
Anthony G.M. Barrett
Doug Ta Hung Chou
Tao Sheng
Michael J.A. Walker
Sandro L. Yong
Original Assignee
Cardiome Pharma Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiome Pharma Corp. filed Critical Cardiome Pharma Corp.
Publication of PL378918A1 publication Critical patent/PL378918A1/pl
Publication of PL227937B1 publication Critical patent/PL227937B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
PL378918A 2003-05-02 2003-10-31 Sposób wytwarzania związku typu eteru aminocykloheksylowego, związek typu eteru aminocykloheksylowego, jego kompozycja, sposób modulowania aktywności kanałów jonowych, oraz zastosowanie związku typu eteru aminocykloheksylowego do wytwarzania leku PL227937B1 (pl)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US46715903P 2003-05-02 2003-05-02
US60/467,159 2003-05-02
US47608303P 2003-06-04 2003-06-04
US60/476,083 2003-06-04
US47591203P 2003-06-05 2003-06-05
US47588403P 2003-06-05 2003-06-05
US47644703P 2003-06-05 2003-06-05
US60/476,447 2003-06-05
US60/475,912 2003-06-05
US60/475,884 2003-06-05
US48965903P 2003-07-23 2003-07-23
US60/489,659 2003-07-23
US49339203P 2003-08-07 2003-08-07
US60/493,392 2003-08-07
PCT/US2003/034655 WO2004099137A1 (en) 2003-05-02 2003-10-31 Aminocyclohexyl ether compounds and uses thereof

Publications (2)

Publication Number Publication Date
PL378918A1 true PL378918A1 (pl) 2006-06-12
PL227937B1 PL227937B1 (pl) 2018-01-31

Family

ID=33437310

Family Applications (1)

Application Number Title Priority Date Filing Date
PL378918A PL227937B1 (pl) 2003-05-02 2003-10-31 Sposób wytwarzania związku typu eteru aminocykloheksylowego, związek typu eteru aminocykloheksylowego, jego kompozycja, sposób modulowania aktywności kanałów jonowych, oraz zastosowanie związku typu eteru aminocykloheksylowego do wytwarzania leku

Country Status (21)

Country Link
US (3) US20070099983A1 (pl)
EP (3) EP1560812B1 (pl)
JP (2) JP4919661B2 (pl)
KR (1) KR101059379B1 (pl)
AT (2) ATE325789T1 (pl)
AU (2) AU2003287378B2 (pl)
BR (2) BR122018009866B8 (pl)
CA (1) CA2524323C (pl)
CY (1) CY1105137T1 (pl)
DE (1) DE60305200T2 (pl)
DK (1) DK1560812T3 (pl)
ES (2) ES2264776T3 (pl)
IL (2) IL171653A (pl)
NO (1) NO334094B1 (pl)
NZ (1) NZ543921A (pl)
PL (1) PL227937B1 (pl)
PT (1) PT1560812E (pl)
RU (1) RU2478617C2 (pl)
SG (2) SG167670A1 (pl)
SI (1) SI1560812T1 (pl)
WO (1) WO2004099137A1 (pl)

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US7345086B2 (en) 2003-05-02 2008-03-18 Cardiome Pharma Corp. Uses of ion channel modulating compounds
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Also Published As

Publication number Publication date
KR101059379B1 (ko) 2011-08-26
SI1560812T1 (sl) 2006-10-31
BRPI0318278B8 (pt) 2024-01-09
RU2008104198A (ru) 2009-08-10
JP4919661B2 (ja) 2012-04-18
RU2478617C2 (ru) 2013-04-10
BRPI0318278B1 (pt) 2018-11-06
IL216579A0 (en) 2012-01-31
CA2524323A1 (en) 2004-11-18
IL171653A (en) 2013-06-27
SG2010079697A (en) 2016-09-29
WO2004099137A1 (en) 2004-11-18
EP1666459B1 (en) 2011-10-19
AU2011201015B2 (en) 2012-02-02
US7767830B2 (en) 2010-08-03
CY1105137T1 (el) 2010-03-03
NO20055130L (no) 2005-12-01
BR0318278A (pt) 2006-05-23
NZ543921A (en) 2008-11-28
NO334094B1 (no) 2013-12-09
SG167670A1 (en) 2011-01-28
JP2007077162A (ja) 2007-03-29
AU2003287378B2 (en) 2010-12-16
BR122018009866B1 (pt) 2018-12-18
AU2003287378A1 (en) 2004-11-26
DK1560812T3 (da) 2006-09-04
DE60305200T2 (de) 2007-05-10
PL227937B1 (pl) 2018-01-31
KR20060057531A (ko) 2006-05-26
DE60305200D1 (de) 2006-06-14
BR122018009866B8 (pt) 2021-07-27
ES2375820T3 (es) 2012-03-06
ATE529401T1 (de) 2011-11-15
EP2298735A1 (en) 2011-03-23
AU2011201015A1 (en) 2011-03-31
PT1560812E (pt) 2006-09-29
ATE325789T1 (de) 2006-06-15
HK1091814A1 (zh) 2007-01-26
CA2524323C (en) 2012-05-15
US8163938B2 (en) 2012-04-24
EP1666459A2 (en) 2006-06-07
US20070254945A1 (en) 2007-11-01
ES2264776T3 (es) 2007-01-16
IL216579A (en) 2015-02-26
EP1560812B1 (en) 2006-05-10
EP1666459A3 (en) 2006-09-20
NO20055130D0 (no) 2005-11-02
EP1560812A1 (en) 2005-08-10
JP2006525227A (ja) 2006-11-09
US20070099983A1 (en) 2007-05-03
US20110004006A1 (en) 2011-01-06

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