PL380766A1 - Benzo[d]izooksazol-3- olowe inhibitory DAAO - Google Patents

Benzo[d]izooksazol-3- olowe inhibitory DAAO

Info

Publication number
PL380766A1
PL380766A1 PL380766A PL38076604A PL380766A1 PL 380766 A1 PL380766 A1 PL 380766A1 PL 380766 A PL380766 A PL 380766A PL 38076604 A PL38076604 A PL 38076604A PL 380766 A1 PL380766 A1 PL 380766A1
Authority
PL
Poland
Prior art keywords
benzisoxazole
daao inhibitors
daao
inhibitors
Prior art date
Application number
PL380766A
Other languages
English (en)
Inventor
Kevin Q. Fang
Seth Hopkins
Steven Jones
Michele Heffernan
Milan Chytil
Original Assignee
Sepracor Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc. filed Critical Sepracor Inc.
Publication of PL380766A1 publication Critical patent/PL380766A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL380766A 2003-12-29 2004-12-28 Benzo[d]izooksazol-3- olowe inhibitory DAAO PL380766A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53297803P 2003-12-29 2003-12-29

Publications (1)

Publication Number Publication Date
PL380766A1 true PL380766A1 (pl) 2007-03-19

Family

ID=34748836

Family Applications (1)

Application Number Title Priority Date Filing Date
PL380766A PL380766A1 (pl) 2003-12-29 2004-12-28 Benzo[d]izooksazol-3- olowe inhibitory DAAO

Country Status (15)

Country Link
US (1) US7166725B2 (pl)
EP (1) EP1711478A2 (pl)
JP (1) JP2007534657A (pl)
KR (1) KR20060128978A (pl)
CN (3) CN102010382A (pl)
AU (1) AU2004312511A1 (pl)
BR (1) BRPI0417910A (pl)
CA (1) CA2552098A1 (pl)
CZ (1) CZ2006426A3 (pl)
IL (1) IL176607A0 (pl)
NZ (1) NZ548213A (pl)
PL (1) PL380766A1 (pl)
RU (1) RU2384574C2 (pl)
WO (1) WO2005066143A2 (pl)
ZA (1) ZA200605384B (pl)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2551952A1 (en) * 2003-12-29 2005-07-21 Sepracor Inc. Pyrrole and pyrazole daao inhibitors
CA2472806A1 (en) 2004-05-18 2005-11-18 Petro-Canada Compositions and methods for treating turf insect pests and diseases such as fungal infestations
WO2007006003A2 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
CN104276955A (zh) 2006-01-06 2015-01-14 赛诺维信制药公司 基于四氢萘酮的单胺再摄取抑制剂
AU2007205114B2 (en) 2006-01-06 2012-11-08 Sunovion Pharmaceuticals Inc. Cycloalkylamines as monoamine reuptake inhibitors
CA2643052C (en) 2006-02-21 2014-02-11 Toyama Chemical Co., Ltd. Process for production of 3-[5-[4-(cyclopentyloxy)-2-hydroxybenzoyl]-2-[(3-oxo-2-substituted-2,3-dihydro-1,2-benzisoxazol-6-yl)methoxy]phenyl]propionate ester and intermediate forthe process
CA2648121C (en) 2006-03-31 2013-08-06 Sepracor Inc. Preparation of chiral amides and amines
US7884124B2 (en) * 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
US9357768B2 (en) 2006-10-05 2016-06-07 Suncor Energy Inc. Herbicidal composition with increased herbicidal efficacy
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
ZA200904686B (en) 2007-01-18 2010-09-29 Sepracor Inc Inhibitiors of D-amino acid oxidase
EP2617704B1 (en) 2007-05-31 2017-06-28 Sunovion Pharmaceuticals Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
NZ590318A (en) 2008-06-26 2012-11-30 Suncor Energy Inc Oil-in-water emulsion fungicide formulation with a phthalocyanine pigment for application to turfgrass
US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
DK3006024T3 (da) 2009-01-20 2019-06-03 Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct Benzoesyre eller salte deraf til forstærkning af aktiviteten af et neurofarmaceutisk lægemiddel
WO2011017634A2 (en) * 2009-08-07 2011-02-10 Sepracore Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
US9226504B2 (en) 2010-09-09 2016-01-05 Suncor Energy Inc. Synergistic paraffinic oil and boscalid fungicides
IN2014KN02990A (pl) 2012-06-04 2015-05-08 Suncor Energy Inc
US9505753B2 (en) 2012-08-08 2016-11-29 The Johns Hopkins University Inhibitors of D-amino acid oxidase
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
CN103435561B (zh) * 2013-08-19 2016-08-10 上海交通大学 一种新型d-氨基酸氧化酶抑制剂及其制备和应用
AU2014386718B8 (en) * 2014-03-24 2017-12-07 China Medical University Use of benzoic acid salt in the manufactue of a composition for preventing or treating dementia or mild cognitive impairment
CN105801511B (zh) * 2016-04-22 2018-01-02 山西大学 一种1,2‑苯并异恶唑啉‑3‑酮的制备方法
MX2018015397A (es) 2016-06-13 2019-08-16 Syneurx Int Taiwan Corp Co-cristales de benzoato de sodio y sus usos.
EP3468946A4 (en) 2016-06-13 2020-02-12 Syneurx International (Taiwan) Corp. CO CRYSTALS OF LITHIUM BENZOATE AND USES THEREOF
CA2938096C (en) 2016-08-04 2019-02-26 Suncor Energy Inc. Stabilized emulsions
US10336679B2 (en) 2016-10-24 2019-07-02 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
US11369579B2 (en) 2016-10-24 2022-06-28 Syneurx International (Taiwan) Corp. Polymorphic forms of sodium benzoate and uses thereof
JP6550426B2 (ja) * 2017-07-26 2019-07-24 カオシュン・チャン・グン・メモリアル・ホスピタル 認知症または軽度認知障害を予防または治療する組成物を製造するための安息香酸塩の使用
WO2019043635A1 (en) 2017-09-01 2019-03-07 Richter Gedeon Nyrt. COMPOUNDS INHIBITING THE ACTIVITY OF D-AMINO ACID OXIDASE
US10336724B2 (en) * 2017-10-18 2019-07-02 Syneurx International (Taiwan) Corp. D-amino acid oxidase inhibitors and therapeutic uses thereof
US10098861B1 (en) 2017-10-24 2018-10-16 Syneurx International (Taiwan) Corp. Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof
AU2020211650B2 (en) 2019-01-25 2025-01-30 Nutrien Ag Solutions (Canada) Inc. Photosensitizer compounds, methods of manufacture and application to plants
MX2021009781A (es) 2019-02-15 2021-09-08 Suncor Energy Inc Derivados de protoporfirina ix y uso de los mismos para mejorar la salud de las plantas.
CN117362246B (zh) * 2023-12-04 2024-03-12 烟台海川化学制品有限公司 一种3-苯基-1,4,2-二恶唑-5-酮的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58177915A (ja) 1982-04-12 1983-10-18 Green Cross Corp:The 抗血栓剤
US4738709A (en) * 1985-01-10 1988-04-19 Ppg Industries, Inc. Herbicidally active substituted benzisoxazoles
JPH0477476A (ja) * 1990-07-19 1992-03-11 Sankyo Co Ltd 抗潰瘍剤
EP0665226A1 (en) * 1992-10-28 1995-08-02 Toyama Chemical Co., Ltd. Novel 1,2-benzisoxazole derivative or salt thereof, and brain protective agent comprising the same
DE69532039T2 (de) * 1994-08-30 2004-07-08 Sankyo Co., Ltd. Isoxazole
US5484763A (en) * 1995-02-10 1996-01-16 American Cyanamid Company Substituted benzisoxazole and benzisothiazole herbicidal agents
US5620997A (en) * 1995-05-31 1997-04-15 Warner-Lambert Company Isothiazolones
DE19960917A1 (de) * 1999-12-17 2001-06-21 Bayer Ag Neue 3-Oxo-2,1-benzisoxazol-1(3H)-carboxamide zur Behandlung von ZNS-Erkrankungen
JP2001247462A (ja) * 2000-03-07 2001-09-11 Otsuka Pharmaceut Co Ltd ウレアーゼ阻害剤
US20070197610A1 (en) 2004-03-16 2007-08-23 Janssen Pharmaceutica N.V. Benzisoxazoles

Also Published As

Publication number Publication date
CN1922157B (zh) 2011-01-12
ZA200605384B (en) 2007-10-31
CN101798291A (zh) 2010-08-11
US7166725B2 (en) 2007-01-23
US20050143434A1 (en) 2005-06-30
NZ548213A (en) 2010-05-28
AU2004312511A1 (en) 2005-07-21
KR20060128978A (ko) 2006-12-14
JP2007534657A (ja) 2007-11-29
RU2384574C2 (ru) 2010-03-20
WO2005066143A3 (en) 2005-10-20
CA2552098A1 (en) 2005-07-21
CN1922157A (zh) 2007-02-28
WO2005066143A2 (en) 2005-07-21
BRPI0417910A (pt) 2007-04-10
IL176607A0 (en) 2006-10-31
RU2006127436A (ru) 2008-02-10
CN102010382A (zh) 2011-04-13
EP1711478A2 (en) 2006-10-18
CZ2006426A3 (cs) 2006-10-11

Similar Documents

Publication Publication Date Title
PL380766A1 (pl) Benzo[d]izooksazol-3- olowe inhibitory DAAO
EG25482A (en) Inhibitors
IL200842A0 (en) Pyrrole daao inhibitors
IL160213A0 (en) Alkyne-aryl phosphodiesterase-4 inhibitors
EP1551801A4 (en) NOVEL GAMMA-LACTAMES AS INHIBITORS OF BETA-SECRETASE
IL173356A0 (en) Improved ratchetable open-ended wrench
GB0329667D0 (en) Core 2 GlcNAc-T inhibitor
EP1532133A4 (en) NF-: B INHIBITORS
IL175220A0 (en) Novel 17?? hydroxysteroid dehydrogenase type i inhibitors
EP1589815A4 (en) POLYCOSANOLS FROM ERICERUS PELA WAX
ZA200505418B (en) Cathepsin S inhibitors
IL164898A0 (en) Heterotricyclyl 6-alkylidene-penems as beta-lactamase inhibitors
EP1622615A4 (en) INHIBITORS OF THE INTEGRASE OF NAPHTHYRIDINE
AP2004003190A0 (en) Broaspectrum substituted benzisoxazole sulfonamideHIV protease inhibitors.
GB0202187D0 (en) "Inhibitors"
GB0311195D0 (en) Glyoxalase inhibitors
AU2003242559A8 (en) Alkylaminosiloxanes as corrosion inhibitors
AU2003232362A8 (en) 4-pyrazol-phenylalanine derivatives as ace-nep inhibitors
PL376540A1 (pl) Pochodne diazepanów stosowane jako inhibitory LFA
GB0312619D0 (en) Complement inhibitors
GB0329869D0 (en) Inhibitors
GB0300607D0 (en) Inhibitors
GB0217330D0 (en) Inhibitors
GB0208094D0 (en) Inhibitors
GB0224102D0 (en) Inhibitors

Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)