BRPI0417910A - composto ou um sal ou salvato farmaceuticamente aceitáveis do mesmo, e, uso de um composto - Google Patents
composto ou um sal ou salvato farmaceuticamente aceitáveis do mesmo, e, uso de um compostoInfo
- Publication number
- BRPI0417910A BRPI0417910A BRPI0417910-2A BRPI0417910A BRPI0417910A BR PI0417910 A BRPI0417910 A BR PI0417910A BR PI0417910 A BRPI0417910 A BR PI0417910A BR PI0417910 A BRPI0417910 A BR PI0417910A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- hydrogen
- solvate
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 150000003839 salts Chemical class 0.000 title abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- MTCFGRXMJLQNBG-UWTATZPHSA-N D-Serine Chemical compound OC[C@@H](N)C(O)=O MTCFGRXMJLQNBG-UWTATZPHSA-N 0.000 abstract 2
- 229930195711 D-Serine Natural products 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 239000012453 solvate Substances 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010003591 Ataxia Diseases 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical group [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical group [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical group [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical group [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical group [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 239000011575 calcium Chemical group 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 230000019771 cognition Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000011777 magnesium Chemical group 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Chemical group 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000003955 neuronal function Effects 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000011591 potassium Chemical group 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 239000011734 sodium Chemical group 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000011701 zinc Chemical group 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
"COMPOSTO OU UM SAL OU SOLVATO FARMACEUTICAMENTE ACEITáVEIS DO MESMO, E, USO DE UM COMPOSTO". Os métodos para aumentar a concentração de D-Serina e reduzir a concentração dos produtos tóxicos da oxidação de D-Serina, para intensificar a aprendizagem, memória e/ou cognição, ou para tratar a esquizofrenia, mal de Alzheimer, ataxia ou dor neuropática ou prevenir a perda na função neuronal característica de doenças neurodegenerativas envolvem administrar a um paciente em necessidade de tratamento uma quantidade terapêutica de um composto da fórmula I ou um sal ou solvato deste farmaceuticamente aceitáveis: em que Z¬ 1¬ é N ou CR3; Z¬ 2¬ é N ou CR4; Z¬ 3¬ é O ou S; A é hidrogênio, alquila ou M¬ +¬; M é alumínio, cálcio, lítio, magnésio, potássio, sódio, zinco ou uma mistura destes; R1, R2, R3 e R4 são independentemente selecionados de hidrogênio, alquila, hidróxi, alcóxi, arila, acila, halo, ciano, haloalquila, NHCOOR5 e SO~ 2~NH~ 2~; R5 é arila, arilalquila, heteroarila ou heteroarilalquila; pelo menos um de R1, R2, R3 e R4 é outro que não hidrogênio; e pelo menos um de Z¬ 1¬ e Z¬ 2¬ é outro que não N.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53297803P | 2003-12-29 | 2003-12-29 | |
| PCT/US2004/043547 WO2005066143A2 (en) | 2003-12-29 | 2004-12-28 | Benzo[d]isoxazol-3-ol daao inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0417910A true BRPI0417910A (pt) | 2007-04-10 |
Family
ID=34748836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0417910-2A BRPI0417910A (pt) | 2003-12-29 | 2004-12-28 | composto ou um sal ou salvato farmaceuticamente aceitáveis do mesmo, e, uso de um composto |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7166725B2 (pt) |
| EP (1) | EP1711478A2 (pt) |
| JP (1) | JP2007534657A (pt) |
| KR (1) | KR20060128978A (pt) |
| CN (3) | CN101798291A (pt) |
| AU (1) | AU2004312511A1 (pt) |
| BR (1) | BRPI0417910A (pt) |
| CA (1) | CA2552098A1 (pt) |
| CZ (1) | CZ2006426A3 (pt) |
| IL (1) | IL176607A0 (pt) |
| NZ (1) | NZ548213A (pt) |
| PL (1) | PL380766A1 (pt) |
| RU (1) | RU2384574C2 (pt) |
| WO (1) | WO2005066143A2 (pt) |
| ZA (1) | ZA200605384B (pt) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1922149A (zh) * | 2003-12-29 | 2007-02-28 | 塞普拉科公司 | 吡咯和吡唑daao抑制剂 |
| CA2472806A1 (en) | 2004-05-18 | 2005-11-18 | Petro-Canada | Compositions and methods for treating turf insect pests and diseases such as fungal infestations |
| CA2614282A1 (en) | 2005-07-06 | 2007-01-11 | Sepracor Inc. | Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders |
| KR101381768B1 (ko) | 2006-01-06 | 2014-04-07 | 선오비온 파마슈티컬스 인코포레이티드 | 테트랄론-기재 모노아민 재흡수 저해제 |
| EP1976513B1 (en) | 2006-01-06 | 2016-08-24 | Sunovion Pharmaceuticals Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| WO2007097279A1 (ja) | 2006-02-21 | 2007-08-30 | Toyama Chemical Co., Ltd. | 3-{5-[4-(シクロペンチルオキシ)-2-ヒドロキシベンゾイル]-2-[(3-オキソ-2-置換-2,3-ジヒドロ-1,2-ベンズイソオキサゾール-6-イル)メトキシ]フェニル}プロピオン酸エステルの製造法およびその中間体 |
| PT2816024T (pt) | 2006-03-31 | 2017-10-20 | Sunovion Pharmaceuticals Inc | Aminas quirais |
| US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
| US9357768B2 (en) | 2006-10-05 | 2016-06-07 | Suncor Energy Inc. | Herbicidal composition with increased herbicidal efficacy |
| US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| JP2010516697A (ja) * | 2007-01-18 | 2010-05-20 | セプラコール インク. | D−アミノ酸オキシダーゼ阻害剤 |
| WO2008151156A1 (en) | 2007-05-31 | 2008-12-11 | Sepracor Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
| CN102215692B (zh) | 2008-06-26 | 2014-10-22 | 森科能源公司 | 含有颜料的改良型草坪草杀真菌制剂 |
| US20100120740A1 (en) * | 2008-08-07 | 2010-05-13 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| ES2731228T3 (es) | 2009-01-20 | 2019-11-14 | Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct | Acido benzoico o sales del mismo para mejorar la actividad de un producto farmacéutico |
| US20110034434A1 (en) * | 2009-08-07 | 2011-02-10 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| WO2012031355A1 (en) | 2010-09-09 | 2012-03-15 | Suncor Energy Inc. | Synergistic paraffinic oil and boscalid fungicides |
| JP2015522554A (ja) | 2012-06-04 | 2015-08-06 | サンコー・エナジー・インコーポレーテッド | パラフィン油及び沈降防止剤を含む製剤 |
| WO2014025993A1 (en) | 2012-08-08 | 2014-02-13 | The Johns Hopkins University | Inhibitors of d-amino acid oxidase |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| CN103435561B (zh) * | 2013-08-19 | 2016-08-10 | 上海交通大学 | 一种新型d-氨基酸氧化酶抑制剂及其制备和应用 |
| WO2015147742A1 (en) * | 2014-03-24 | 2015-10-01 | Kaohsiung Chang Gung Memorial Hospital | Use of benzoic acid salt in the manufactue of a composition for preventing or treating dementia or mild cognitive impairment |
| CN105801511B (zh) * | 2016-04-22 | 2018-01-02 | 山西大学 | 一种1,2‑苯并异恶唑啉‑3‑酮的制备方法 |
| KR102403048B1 (ko) | 2016-06-13 | 2022-05-26 | 신유알엑스 인터내셔널 (타이완) 코포레이션 | 벤조산나트륨의 공-결정 및 그의 용도 |
| TWI736635B (zh) | 2016-06-13 | 2021-08-21 | 心悅生醫股份有限公司 | 苯甲酸鋰之共晶及其用途 |
| CA2938096C (en) | 2016-08-04 | 2019-02-26 | Suncor Energy Inc. | Stabilized emulsions |
| US11369579B2 (en) | 2016-10-24 | 2022-06-28 | Syneurx International (Taiwan) Corp. | Polymorphic forms of sodium benzoate and uses thereof |
| US10336679B2 (en) | 2016-10-24 | 2019-07-02 | Syneurx International (Taiwan) Corp. | Polymorphic forms of sodium benzoate and uses thereof |
| JP6550426B2 (ja) * | 2017-07-26 | 2019-07-24 | カオシュン・チャン・グン・メモリアル・ホスピタル | 認知症または軽度認知障害を予防または治療する組成物を製造するための安息香酸塩の使用 |
| WO2019043635A1 (en) | 2017-09-01 | 2019-03-07 | Richter Gedeon Nyrt. | COMPOUNDS INHIBITING THE ACTIVITY OF D-AMINO ACID OXIDASE |
| US10336724B2 (en) * | 2017-10-18 | 2019-07-02 | Syneurx International (Taiwan) Corp. | D-amino acid oxidase inhibitors and therapeutic uses thereof |
| US10098861B1 (en) | 2017-10-24 | 2018-10-16 | Syneurx International (Taiwan) Corp. | Pharmaceutical composition comprising sodium benzoate compound and clozapine, and uses thereof |
| MX2021008944A (es) | 2019-01-25 | 2021-08-24 | Suncor Energy Inc | Compuestos fotosensibilizadores, metodos de fabricacion y aplicacion a las plantas. |
| AU2020222515B2 (en) | 2019-02-15 | 2025-10-09 | Nutrien Ag Solutions (Canada) Inc. | The use of protoporphyrin IX derivatives to improve the health of plants |
| CN117362246B (zh) * | 2023-12-04 | 2024-03-12 | 烟台海川化学制品有限公司 | 一种3-苯基-1,4,2-二恶唑-5-酮的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58177915A (ja) * | 1982-04-12 | 1983-10-18 | Green Cross Corp:The | 抗血栓剤 |
| US4738709A (en) | 1985-01-10 | 1988-04-19 | Ppg Industries, Inc. | Herbicidally active substituted benzisoxazoles |
| JPH0477476A (ja) * | 1990-07-19 | 1992-03-11 | Sankyo Co Ltd | 抗潰瘍剤 |
| WO1994010158A1 (fr) | 1992-10-28 | 1994-05-11 | Toyama Chemical Co., Ltd. | Nouveaux derives de 1,2-benzisoxazole ou sel dudit derive, et agent de protection cerebrale contenant ce derive |
| AU688102B2 (en) * | 1994-08-30 | 1998-03-05 | Sankyo Company Limited | Isoxazoles |
| US5484763A (en) | 1995-02-10 | 1996-01-16 | American Cyanamid Company | Substituted benzisoxazole and benzisothiazole herbicidal agents |
| US5620997A (en) * | 1995-05-31 | 1997-04-15 | Warner-Lambert Company | Isothiazolones |
| DE19960917A1 (de) * | 1999-12-17 | 2001-06-21 | Bayer Ag | Neue 3-Oxo-2,1-benzisoxazol-1(3H)-carboxamide zur Behandlung von ZNS-Erkrankungen |
| JP2001247462A (ja) * | 2000-03-07 | 2001-09-11 | Otsuka Pharmaceut Co Ltd | ウレアーゼ阻害剤 |
| WO2005089753A2 (en) | 2004-03-16 | 2005-09-29 | Janssen Pharmaceutica N.V. | Daao inhibiting bξnzisoxazoles and their use for the treatment of mental disorders |
-
2004
- 2004-12-28 ZA ZA200605384A patent/ZA200605384B/en unknown
- 2004-12-28 AU AU2004312511A patent/AU2004312511A1/en not_active Abandoned
- 2004-12-28 PL PL380766A patent/PL380766A1/pl not_active Application Discontinuation
- 2004-12-28 US US11/024,151 patent/US7166725B2/en not_active Expired - Lifetime
- 2004-12-28 EP EP04815603A patent/EP1711478A2/en not_active Withdrawn
- 2004-12-28 WO PCT/US2004/043547 patent/WO2005066143A2/en not_active Ceased
- 2004-12-28 RU RU2006127436/04A patent/RU2384574C2/ru not_active IP Right Cessation
- 2004-12-28 CN CN201010150424A patent/CN101798291A/zh active Pending
- 2004-12-28 CA CA002552098A patent/CA2552098A1/en not_active Abandoned
- 2004-12-28 JP JP2006547443A patent/JP2007534657A/ja active Pending
- 2004-12-28 KR KR1020067015383A patent/KR20060128978A/ko not_active Ceased
- 2004-12-28 NZ NZ548213A patent/NZ548213A/en unknown
- 2004-12-28 CN CN2004800422050A patent/CN1922157B/zh not_active Expired - Fee Related
- 2004-12-28 BR BRPI0417910-2A patent/BRPI0417910A/pt not_active Application Discontinuation
- 2004-12-28 CZ CZ20060426A patent/CZ2006426A3/cs unknown
- 2004-12-28 CN CN2010105590539A patent/CN102010382A/zh active Pending
-
2006
- 2006-06-28 IL IL176607A patent/IL176607A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007534657A (ja) | 2007-11-29 |
| RU2384574C2 (ru) | 2010-03-20 |
| CZ2006426A3 (cs) | 2006-10-11 |
| WO2005066143A2 (en) | 2005-07-21 |
| CN1922157B (zh) | 2011-01-12 |
| US7166725B2 (en) | 2007-01-23 |
| CN102010382A (zh) | 2011-04-13 |
| CA2552098A1 (en) | 2005-07-21 |
| US20050143434A1 (en) | 2005-06-30 |
| AU2004312511A1 (en) | 2005-07-21 |
| EP1711478A2 (en) | 2006-10-18 |
| KR20060128978A (ko) | 2006-12-14 |
| CN101798291A (zh) | 2010-08-11 |
| PL380766A1 (pl) | 2007-03-19 |
| IL176607A0 (en) | 2006-10-31 |
| ZA200605384B (en) | 2007-10-31 |
| RU2006127436A (ru) | 2008-02-10 |
| CN1922157A (zh) | 2007-02-28 |
| NZ548213A (en) | 2010-05-28 |
| WO2005066143A3 (en) | 2005-10-20 |
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