PL3810128T3 - Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek - Google Patents

Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek

Info

Publication number
PL3810128T3
PL3810128T3 PL19730826.5T PL19730826T PL3810128T3 PL 3810128 T3 PL3810128 T3 PL 3810128T3 PL 19730826 T PL19730826 T PL 19730826T PL 3810128 T3 PL3810128 T3 PL 3810128T3
Authority
PL
Poland
Prior art keywords
prevention
compositions
treatment
protein aggregation
aggregation diseases
Prior art date
Application number
PL19730826.5T
Other languages
English (en)
Inventor
Manuel J. MUÑOZ
Ángel M. CARRIÓN
Mercedes M. PÉREZ-JIMÉNEZ
Original Assignee
Universidad Pablo De Olavide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Pablo De Olavide filed Critical Universidad Pablo De Olavide
Publication of PL3810128T3 publication Critical patent/PL3810128T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
PL19730826.5T 2018-06-19 2019-06-19 Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek PL3810128T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18382439 2018-06-19
PCT/EP2019/066271 WO2019243453A1 (en) 2018-06-19 2019-06-19 Compositions for treating and/or preventing protein-aggregation diseases

Publications (1)

Publication Number Publication Date
PL3810128T3 true PL3810128T3 (pl) 2023-01-30

Family

ID=62716030

Family Applications (2)

Application Number Title Priority Date Filing Date
PL22186334.3T PL4094754T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom
PL19730826.5T PL3810128T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia i/lub zapobiegania chorobom związanym z agregacją białek

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL22186334.3T PL4094754T3 (pl) 2018-06-19 2019-06-19 Kompozycje do leczenia chorób związanych z agregacją białek i/lub zapobiegania takim chorobom

Country Status (17)

Country Link
US (2) US20210251953A1 (pl)
EP (2) EP4094754B1 (pl)
JP (2) JP2021528442A (pl)
CN (2) CN118845759A (pl)
AU (1) AU2019291061B2 (pl)
BR (1) BR112020026066A2 (pl)
CA (1) CA3103834A1 (pl)
DK (1) DK3810128T3 (pl)
ES (2) ES3044215T3 (pl)
HR (1) HRP20251214T1 (pl)
HU (1) HUE073261T2 (pl)
MX (1) MX2020014070A (pl)
PL (2) PL4094754T3 (pl)
PT (1) PT3810128T (pl)
RS (1) RS67299B1 (pl)
SM (1) SMT202500382T1 (pl)
WO (1) WO2019243453A1 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
WO2019243453A1 (en) * 2018-06-19 2019-12-26 Universidad Pablo De Olavide Compositions for treating and/or preventing protein-aggregation diseases
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
EP3988096A1 (en) * 2020-10-26 2022-04-27 Universidad Pablo de Olavide OTRI Sulfated c19 steroid hormones to treat and/or prevent proteotoxicity in protein-aggregation diseases
CN112552272B (zh) * 2020-12-22 2023-06-27 四川大学 香豆素类化合物及其制备方法和应用、药物组合物
EP4252748A1 (en) * 2022-03-31 2023-10-04 Otto-von-Guericke-University Magdeburg A sphingosine-1-phosphate receptor (s1pr) modulator for use in treating a patient suffering from alzheimer's dementia

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9603325D0 (en) 1996-02-16 1996-04-17 Imperial College A compound
US5556847A (en) * 1994-10-27 1996-09-17 Duquesne University Of The Holy Ghost Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors
JP4320089B2 (ja) * 1999-07-06 2009-08-26 あすか製薬株式会社 フェニルスルファメート誘導体
US20060183776A9 (en) * 2000-03-03 2006-08-17 Eisai Co., Ltd. Liquid dosage formulations of donepezil
EP2133078A1 (en) * 2000-03-03 2009-12-16 Eisai R&D Management Co., Ltd. Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments
GB0511190D0 (en) * 2005-06-01 2005-07-06 Sterix Ltd Use
ES2514140B1 (es) * 2013-03-26 2015-08-03 Universidad Pablo De Olavide Uso del inhibidor de sulfatasas esteroideas STX64 para el tratamiento del envejecimiento
US10155936B2 (en) * 2014-12-05 2018-12-18 An2H Discovery Limited Parkin ligase activation methods and compositions
WO2017075540A1 (en) 2015-10-30 2017-05-04 Ultragenyx Pharmaceutical Inc. Methods and compositions for the treatment of amyloidosis
US10780094B2 (en) * 2016-07-22 2020-09-22 New York University Use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders
WO2019243453A1 (en) * 2018-06-19 2019-12-26 Universidad Pablo De Olavide Compositions for treating and/or preventing protein-aggregation diseases

Also Published As

Publication number Publication date
CN118845759A (zh) 2024-10-29
DK3810128T3 (da) 2022-10-31
RS67299B1 (sr) 2025-11-28
CN112601521A (zh) 2021-04-02
PT3810128T (pt) 2022-11-09
SMT202500382T1 (it) 2025-11-10
JP2021528442A (ja) 2021-10-21
ES3044215T3 (en) 2025-11-26
US20260083700A1 (en) 2026-03-26
PL4094754T3 (pl) 2026-01-05
HUE073261T2 (hu) 2026-01-28
EP4094754C0 (en) 2025-08-06
EP3810128A1 (en) 2021-04-28
EP4094754B1 (en) 2025-08-06
WO2019243453A1 (en) 2019-12-26
CA3103834A1 (en) 2019-12-26
MX2020014070A (es) 2021-05-27
EP4094754A1 (en) 2022-11-30
JP2024059803A (ja) 2024-05-01
ES2931815T3 (es) 2023-01-02
BR112020026066A2 (pt) 2021-03-23
AU2019291061A1 (en) 2021-02-04
EP3810128B1 (en) 2022-08-03
AU2019291061B2 (en) 2025-04-10
HRP20251214T1 (hr) 2025-12-19
US20210251953A1 (en) 2021-08-19

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