PL3823623T3 - Podstawiony związek aminopirymidynowy do zastosowania w metodzie leczenia i zapobiegania stwardnieniu rozsianemu - Google Patents
Podstawiony związek aminopirymidynowy do zastosowania w metodzie leczenia i zapobiegania stwardnieniu rozsianemuInfo
- Publication number
- PL3823623T3 PL3823623T3 PL19768898.9T PL19768898T PL3823623T3 PL 3823623 T3 PL3823623 T3 PL 3823623T3 PL 19768898 T PL19768898 T PL 19768898T PL 3823623 T3 PL3823623 T3 PL 3823623T3
- Authority
- PL
- Poland
- Prior art keywords
- treatment
- multiple sclerosis
- preventing multiple
- aminopyrimidine compound
- substituted aminopyrimidine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862700977P | 2018-07-20 | 2018-07-20 | |
| US201862730184P | 2018-09-12 | 2018-09-12 | |
| US201962839273P | 2019-04-26 | 2019-04-26 | |
| PCT/IB2019/056198 WO2020016850A1 (en) | 2018-07-20 | 2019-07-19 | A substituted amino-pyrimidine compound for use in a method for treatment and prevention of multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3823623T3 true PL3823623T3 (pl) | 2025-03-24 |
Family
ID=67953828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL19768898.9T PL3823623T3 (pl) | 2018-07-20 | 2019-07-19 | Podstawiony związek aminopirymidynowy do zastosowania w metodzie leczenia i zapobiegania stwardnieniu rozsianemu |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US12251382B2 (pl) |
| EP (1) | EP3823623B1 (pl) |
| JP (1) | JP7724151B2 (pl) |
| KR (1) | KR102912872B1 (pl) |
| CN (1) | CN112437665A (pl) |
| AU (2) | AU2019306828A1 (pl) |
| BR (1) | BR112021000893A2 (pl) |
| CA (1) | CA3106772A1 (pl) |
| DK (1) | DK3823623T3 (pl) |
| ES (1) | ES3009670T3 (pl) |
| FI (1) | FI3823623T3 (pl) |
| HR (1) | HRP20241737T1 (pl) |
| HU (1) | HUE069840T2 (pl) |
| IL (1) | IL280197B2 (pl) |
| MX (1) | MX2021000094A (pl) |
| PL (1) | PL3823623T3 (pl) |
| PT (1) | PT3823623T (pl) |
| SG (1) | SG11202100518TA (pl) |
| TW (1) | TWI879737B (pl) |
| UA (1) | UA127744C2 (pl) |
| WO (1) | WO2020016850A1 (pl) |
| ZA (1) | ZA202101118B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3168146A1 (en) * | 2020-01-20 | 2021-07-29 | Genzyme Corporation | Therapeutic tyrosine kinase inhibitors for relapsing multiple sclerosis (rms) |
| TWI899163B (zh) * | 2020-02-28 | 2025-10-01 | 美商建南德克公司 | 使用布魯頓氏酪胺酸激酶之抑制劑來治療首發漸進型多發性硬化症之方法 |
| BR112023021235A2 (pt) | 2021-05-14 | 2023-12-12 | Loxo Oncology Inc | Formas cocristalinas de um inibidor da tirosina quinase de bruton |
| US20240327379A1 (en) * | 2021-07-15 | 2024-10-03 | Sandoz Ag | Mandelate form of 1-(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one |
| US20260000669A1 (en) | 2022-06-24 | 2026-01-01 | Merck Patent Gmbh | Treatment regimen for autoimmune diseases and inflammatory diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10060388A1 (de) * | 2000-12-05 | 2002-06-06 | Merck Patent Gmbh | Verwendung von Pyrazolo [4,3-d]pyrimidinen |
| WO2011156900A2 (en) * | 2010-06-17 | 2011-12-22 | Waratah Pharmaceuticals Inc. | Compounds, compositions and methods for treatment of multiple sclerosis |
| US9073947B2 (en) * | 2011-06-10 | 2015-07-07 | Merck Patent Gmbh | Compositions and methods for the production of pyrimidine and pyridine compounds with BTK inhibitory activity |
| TW201728592A (zh) * | 2012-01-10 | 2017-08-16 | 林伯士艾瑞斯公司 | Ｉｒａｋ抑制劑及其用途 |
| TW201804997A (zh) * | 2012-05-02 | 2018-02-16 | 以色列商泰瓦藥品工業有限公司 | 高劑量拉喹莫德(laquinimod)於治療多發性硬化症之用途 |
| KR102780243B1 (ko) | 2015-11-17 | 2025-03-14 | 메르크 파텐트 게엠베하 | Btk 억제 활성을 갖는 피리미딘 및 피리딘 화합물을 사용하여 다발성 경화증을 치료하는 방법 |
| US10464923B2 (en) * | 2017-02-27 | 2019-11-05 | Merck Patent Gmbh | Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone |
-
2019
- 2019-07-19 MX MX2021000094A patent/MX2021000094A/es unknown
- 2019-07-19 FI FIEP19768898.9T patent/FI3823623T3/fi active
- 2019-07-19 SG SG11202100518TA patent/SG11202100518TA/en unknown
- 2019-07-19 JP JP2021503059A patent/JP7724151B2/ja active Active
- 2019-07-19 HU HUE19768898A patent/HUE069840T2/hu unknown
- 2019-07-19 PT PT197688989T patent/PT3823623T/pt unknown
- 2019-07-19 ES ES19768898T patent/ES3009670T3/es active Active
- 2019-07-19 PL PL19768898.9T patent/PL3823623T3/pl unknown
- 2019-07-19 US US17/261,407 patent/US12251382B2/en active Active
- 2019-07-19 CN CN201980048404.9A patent/CN112437665A/zh active Pending
- 2019-07-19 CA CA3106772A patent/CA3106772A1/en active Pending
- 2019-07-19 EP EP19768898.9A patent/EP3823623B1/en active Active
- 2019-07-19 TW TW108125526A patent/TWI879737B/zh active
- 2019-07-19 WO PCT/IB2019/056198 patent/WO2020016850A1/en not_active Ceased
- 2019-07-19 KR KR1020217004655A patent/KR102912872B1/ko active Active
- 2019-07-19 BR BR112021000893-4A patent/BR112021000893A2/pt unknown
- 2019-07-19 DK DK19768898.9T patent/DK3823623T3/da active
- 2019-07-19 UA UAA202100604A patent/UA127744C2/uk unknown
- 2019-07-19 HR HRP20241737TT patent/HRP20241737T1/hr unknown
- 2019-07-19 AU AU2019306828A patent/AU2019306828A1/en not_active Abandoned
-
2021
- 2021-01-14 IL IL280197A patent/IL280197B2/en unknown
- 2021-02-18 ZA ZA2021/01118A patent/ZA202101118B/en unknown
-
2025
- 2025-05-05 AU AU2025203171A patent/AU2025203171A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW202019425A (zh) | 2020-06-01 |
| HUE069840T2 (hu) | 2025-04-28 |
| AU2025203171A1 (en) | 2025-05-22 |
| UA127744C2 (uk) | 2023-12-20 |
| MX2021000094A (es) | 2021-03-25 |
| JP7724151B2 (ja) | 2025-08-15 |
| EP3823623B1 (en) | 2024-10-09 |
| BR112021000893A2 (pt) | 2021-04-13 |
| ZA202101118B (en) | 2025-06-25 |
| TWI879737B (zh) | 2025-04-11 |
| US20210260060A1 (en) | 2021-08-26 |
| EP3823623A1 (en) | 2021-05-26 |
| DK3823623T3 (da) | 2025-01-02 |
| KR102912872B1 (ko) | 2026-01-15 |
| IL280197A (en) | 2021-03-01 |
| IL280197B1 (en) | 2026-03-01 |
| CN112437665A (zh) | 2021-03-02 |
| JP2021532104A (ja) | 2021-11-25 |
| KR20210034623A (ko) | 2021-03-30 |
| FI3823623T3 (fi) | 2025-01-09 |
| WO2020016850A1 (en) | 2020-01-23 |
| IL280197B2 (en) | 2026-07-01 |
| US12251382B2 (en) | 2025-03-18 |
| ES3009670T3 (en) | 2025-03-31 |
| PT3823623T (pt) | 2025-01-06 |
| AU2019306828A1 (en) | 2021-03-11 |
| HRP20241737T1 (hr) | 2025-02-28 |
| SG11202100518TA (en) | 2021-02-25 |
| CA3106772A1 (en) | 2020-01-23 |
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