PL382769A1 - Kaseta ekspresyjna, cząsteczka T-DNA, roślinny wektor ekspresyjny, transgeniczna komórka roślinna oraz ich zastosowanie do wytwarzania szczepionki - Google Patents

Kaseta ekspresyjna, cząsteczka T-DNA, roślinny wektor ekspresyjny, transgeniczna komórka roślinna oraz ich zastosowanie do wytwarzania szczepionki

Info

Publication number
PL382769A1
PL382769A1 PL38276907A PL38276907A PL382769A1 PL 382769 A1 PL382769 A1 PL 382769A1 PL 38276907 A PL38276907 A PL 38276907A PL 38276907 A PL38276907 A PL 38276907A PL 382769 A1 PL382769 A1 PL 382769A1
Authority
PL
Poland
Prior art keywords
vaccine
production
application
expression vector
dna particle
Prior art date
Application number
PL38276907A
Other languages
English (en)
Other versions
PL213496B1 (pl
Inventor
Tomasz Pniewski
Józef Kapusta
Piotr Bociąg
Anna Kostrzak
Bogdan Wolko
Andrzej Płucienniczak
Grażyna Płucienniczak
Piotr Wójcik
Halina Otta
Jacek Wojciechowicz
Original Assignee
Instytut Genetyki Roślin Polskiej Akademii Nauk
Instytut Biotechnologii i Antybiotyków
Instytut Roślin i Przetworów Zielarskich
Medana Pharma Terpol Group Spółka Akcyjna
Jacek Wojciechowicz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Genetyki Roślin Polskiej Akademii Nauk, Instytut Biotechnologii i Antybiotyków, Instytut Roślin i Przetworów Zielarskich, Medana Pharma Terpol Group Spółka Akcyjna, Jacek Wojciechowicz filed Critical Instytut Genetyki Roślin Polskiej Akademii Nauk
Priority to PL382769A priority Critical patent/PL213496B1/pl
Priority to PCT/PL2008/000046 priority patent/WO2009002198A2/en
Priority to EP08779135.6A priority patent/EP2173885B1/en
Priority to US12/668,693 priority patent/US20100313298A1/en
Publication of PL382769A1 publication Critical patent/PL382769A1/pl
Publication of PL213496B1 publication Critical patent/PL213496B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517—Plant cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL382769A 2007-06-28 2007-06-28 Czasteczka T-DNA, wektor ekspresyjny, zawierajaca go komórka E.coli oraz Agrobacterium tumefaciens, transgeniczna komórka roslinna oraz ich zastosowanie PL213496B1 (pl)

Priority Applications (4)

Application Number Priority Date Filing Date Title
PL382769A PL213496B1 (pl) 2007-06-28 2007-06-28 Czasteczka T-DNA, wektor ekspresyjny, zawierajaca go komórka E.coli oraz Agrobacterium tumefaciens, transgeniczna komórka roslinna oraz ich zastosowanie
PCT/PL2008/000046 WO2009002198A2 (en) 2007-06-28 2008-06-26 Expression cassette, t-dna molecule, plant expression vector, transgenic plant cell as well as their use in the manufacturing of a vaccine
EP08779135.6A EP2173885B1 (en) 2007-06-28 2008-06-26 Expression cassette, t-dna molecule, plant expression vector, transgenic plant cell as well as their use in the manufacturing of a vaccine
US12/668,693 US20100313298A1 (en) 2007-06-28 2008-06-26 Expression cassette, t-dna molecule, plant expression vector, transgenic plant cell as well as their use in the manufacturing of a vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL382769A PL213496B1 (pl) 2007-06-28 2007-06-28 Czasteczka T-DNA, wektor ekspresyjny, zawierajaca go komórka E.coli oraz Agrobacterium tumefaciens, transgeniczna komórka roslinna oraz ich zastosowanie

Publications (2)

Publication Number Publication Date
PL382769A1 true PL382769A1 (pl) 2009-01-05
PL213496B1 PL213496B1 (pl) 2013-03-29

Family

ID=40019281

Family Applications (1)

Application Number Title Priority Date Filing Date
PL382769A PL213496B1 (pl) 2007-06-28 2007-06-28 Czasteczka T-DNA, wektor ekspresyjny, zawierajaca go komórka E.coli oraz Agrobacterium tumefaciens, transgeniczna komórka roslinna oraz ich zastosowanie

Country Status (4)

Country Link
US (1) US20100313298A1 (pl)
EP (1) EP2173885B1 (pl)
PL (1) PL213496B1 (pl)
WO (1) WO2009002198A2 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085162A2 (en) 2009-01-23 2010-07-29 Instytut Genetyki Roślin Polskiej Akademii Nauk Expression cassettes, T-DNA molecules, plant expression vectors, transgenic plant cells as well as the use thereof in the production of a vaccine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110229847A (zh) * 2019-06-24 2019-09-13 王跃驹 生菜作为宿主在表达乙肝疫苗中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612487A (en) * 1991-08-26 1997-03-18 Edible Vaccines, Inc. Anti-viral vaccines expressed in plants
EP1230257A4 (en) * 1998-12-23 2003-08-13 Thompson Boyce Plant Res EXPRESSION OF IMMUNOGENIC HEPATITIS B SURFACE ANTIGENS IN TRANSGENIC PLANTS
US7527810B1 (en) * 1999-10-13 2009-05-05 Health Research, Inc. Oral immunology using plant product containing hepatitis surface antigen
EP1423508B1 (en) * 2001-09-05 2012-01-18 BASF Plant Science GmbH Protein phosphatase stress-related polypeptides and methods of use in plants

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085162A2 (en) 2009-01-23 2010-07-29 Instytut Genetyki Roślin Polskiej Akademii Nauk Expression cassettes, T-DNA molecules, plant expression vectors, transgenic plant cells as well as the use thereof in the production of a vaccine

Also Published As

Publication number Publication date
PL213496B1 (pl) 2013-03-29
US20100313298A1 (en) 2010-12-09
WO2009002198A2 (en) 2008-12-31
WO2009002198A3 (en) 2009-02-19
EP2173885A2 (en) 2010-04-14
EP2173885B1 (en) 2017-05-03

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