PL3830084T3 - Sposoby oczyszczania siarczanu izawukonazonium - Google Patents

Sposoby oczyszczania siarczanu izawukonazonium

Info

Publication number
PL3830084T3
PL3830084T3 PL19755292.0T PL19755292T PL3830084T3 PL 3830084 T3 PL3830084 T3 PL 3830084T3 PL 19755292 T PL19755292 T PL 19755292T PL 3830084 T3 PL3830084 T3 PL 3830084T3
Authority
PL
Poland
Prior art keywords
purifying
methods
isavuconazonium sulfate
isavuconazonium
sulfate
Prior art date
Application number
PL19755292.0T
Other languages
English (en)
Inventor
Weipeng ZENG
Marco Mazzotti
Lars Vicum
Jeroen CORNEL
Markus Heubes
Michael Schleimer
Original Assignee
Basilea Pharmaceutica International Ag, Allschwil
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica International Ag, Allschwil filed Critical Basilea Pharmaceutica International Ag, Allschwil
Publication of PL3830084T3 publication Critical patent/PL3830084T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL19755292.0T 2018-08-01 2019-07-29 Sposoby oczyszczania siarczanu izawukonazonium PL3830084T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018097881 2018-08-01
CN2019090347 2019-06-06
PCT/EP2019/070385 WO2020025553A1 (en) 2018-08-01 2019-07-29 Methods for purifying isavuconazonium sulfate

Publications (1)

Publication Number Publication Date
PL3830084T3 true PL3830084T3 (pl) 2026-01-26

Family

ID=67660058

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19755292.0T PL3830084T3 (pl) 2018-08-01 2019-07-29 Sposoby oczyszczania siarczanu izawukonazonium

Country Status (17)

Country Link
US (1) US12428414B2 (pl)
EP (1) EP3830084B1 (pl)
JP (1) JP7433288B2 (pl)
KR (1) KR102835134B1 (pl)
CN (1) CN112469717B (pl)
AU (1) AU2019313525A1 (pl)
BR (1) BR112021000486A2 (pl)
CA (1) CA3103888A1 (pl)
ES (1) ES3050832T3 (pl)
HR (1) HRP20251022T1 (pl)
HU (1) HUE073470T2 (pl)
IL (1) IL279667A (pl)
MX (1) MX2021001116A (pl)
PL (1) PL3830084T3 (pl)
SG (1) SG11202100894XA (pl)
TW (1) TWI842726B (pl)
WO (1) WO2020025553A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240145001A (ko) * 2022-02-04 2024-10-04 글렌마크 라이프 사이언시즈 리미티드 이사부코나조늄 황산염의 결정질 형태 및 이의 제조 방법
WO2023238014A1 (en) * 2022-06-09 2023-12-14 Optimus Drugs Private Limited Crystalline form p of isavuconazonium sulfate
CN116768879B (zh) * 2023-06-15 2025-12-23 上海方予健康医药科技有限公司 一种抗真菌药物的合成方法
WO2025008993A1 (en) * 2023-07-04 2025-01-09 Msn Laboratories Private Limited, R&D Center Improved process for the preparation of Glycine, N-methyl-, [2-[[[1-[1-((2R,3R)-3-[4-(4-cyanophenyl)-2-thiazolyl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4H-1,2,4-triazolium-4-yl]ethoxy]carbonyl]methylamino]-3-pyridinyl]methyl ester, sulfate (1:1)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1185230C (zh) 1999-11-02 2005-01-19 巴斯利尔药物股份公司 N-取代的氨基甲酰氧基烷基-吡咯鎓衍生物
HRP20171459T1 (hr) * 2012-12-07 2017-11-03 F. Hoffmann - La Roche Ag Piridin-2-amidi korisni kao agonisti cb2
WO2015150947A1 (en) 2014-03-29 2015-10-08 Wockhardt Limited A process for the preparation of isavuconazole and its intermediates
WO2016016766A2 (en) * 2014-07-26 2016-02-04 Wockhardt Limited A process for the preparation of isavuconazonium or its salt thereof
WO2016055918A1 (en) 2014-10-08 2016-04-14 Wockhardt Limited Novel stable polymorphs of isavuconazole or its salt thereof
CN106467534B (zh) 2015-08-17 2019-10-11 江苏奥赛康药业有限公司 一种硫酸艾沙康唑鎓化合物及其药物组合物
CN106543165A (zh) 2015-09-21 2017-03-29 天津市汉康医药生物技术有限公司 艾沙康唑化合物
CN106565699B (zh) 2015-10-10 2019-07-26 江苏正大丰海制药有限公司 一种艾沙康唑硫酸盐晶体及其制备方法
CN107778306B (zh) 2016-08-30 2020-10-16 江苏奥赛康药业有限公司 一种艾沙康唑化合物及其制备方法
IN201621035182A (pl) 2016-10-14 2019-10-25
CN106619541A (zh) 2016-10-27 2017-05-10 南京师范大学 艾沙康唑鎓硫酸盐冻干粉针剂及制备方法
CN107982221A (zh) 2016-10-27 2018-05-04 江苏正大丰海制药有限公司 注射用硫酸艾沙康唑鎓冻干粉针剂及制备方法
CN106749221B (zh) 2016-12-15 2019-06-21 扬子江药业集团有限公司 艾沙康唑一水合物晶型及其制备方法
CN106749222B (zh) 2016-12-15 2019-06-11 重庆东得医药科技有限公司 艾沙康唑的晶型a及其制备方法、药物组合物和用途
CN106883226A (zh) * 2017-03-30 2017-06-23 成都绿林科技有限公司 艾莎康唑硫酸酯的制备方法
CN106916152B (zh) * 2017-04-27 2019-09-17 扬子江药业集团有限公司 氧化还原反应制备艾沙康唑鎓单硫酸盐的方法
CN109206421A (zh) 2017-07-03 2019-01-15 上海医药集团股份有限公司 一种艾沙康唑晶型及其制备方法
CN107445951A (zh) 2017-07-29 2017-12-08 上海键合医药科技有限公司 一种硫酸艾沙康唑鎓非对映异构体杂质的制备方法和用途
CN107661298B (zh) 2017-10-17 2022-05-27 上海键合医药科技有限公司 一种注射用硫酸艾沙康唑鎓及其冻干工艺

Also Published As

Publication number Publication date
ES3050832T3 (en) 2025-12-23
IL279667A (en) 2021-03-01
KR20210040034A (ko) 2021-04-12
TWI842726B (zh) 2024-05-21
AU2019313525A1 (en) 2021-01-07
HRP20251022T1 (hr) 2025-10-24
EP3830084C0 (en) 2025-08-06
BR112021000486A2 (pt) 2021-04-06
HUE073470T2 (hu) 2026-01-28
MX2021001116A (es) 2021-03-31
CN112469717B (zh) 2025-05-23
CA3103888A1 (en) 2020-02-06
TW202019920A (zh) 2020-06-01
US20210323959A1 (en) 2021-10-21
JP7433288B2 (ja) 2024-02-19
WO2020025553A1 (en) 2020-02-06
US12428414B2 (en) 2025-09-30
JP2021533116A (ja) 2021-12-02
CN112469717A (zh) 2021-03-09
KR102835134B1 (ko) 2025-07-16
EP3830084A1 (en) 2021-06-09
EP3830084B1 (en) 2025-08-06
SG11202100894XA (en) 2021-02-25

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