PL3840837T3 - Inhibitory arginazy i sposoby ich zastosowania - Google Patents

Inhibitory arginazy i sposoby ich zastosowania

Info

Publication number
PL3840837T3
PL3840837T3 PL19758683.7T PL19758683T PL3840837T3 PL 3840837 T3 PL3840837 T3 PL 3840837T3 PL 19758683 T PL19758683 T PL 19758683T PL 3840837 T3 PL3840837 T3 PL 3840837T3
Authority
PL
Poland
Prior art keywords
methods
arginase inhibitors
arginase
inhibitors
Prior art date
Application number
PL19758683.7T
Other languages
English (en)
Inventor
Dedong Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PL3840837T3 publication Critical patent/PL3840837T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/22Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL19758683.7T 2018-08-22 2019-08-21 Inhibitory arginazy i sposoby ich zastosowania PL3840837T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862721113P 2018-08-22 2018-08-22
PCT/EP2019/072341 WO2020038983A1 (en) 2018-08-22 2019-08-21 Arginase inhibitors and methods of use thereof

Publications (1)

Publication Number Publication Date
PL3840837T3 true PL3840837T3 (pl) 2024-08-19

Family

ID=67742403

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19758683.7T PL3840837T3 (pl) 2018-08-22 2019-08-21 Inhibitory arginazy i sposoby ich zastosowania

Country Status (25)

Country Link
US (1) US11952392B2 (pl)
EP (2) EP4371614A3 (pl)
JP (1) JP7441210B2 (pl)
KR (1) KR102668252B1 (pl)
CN (1) CN112584900B (pl)
AU (1) AU2019323663B2 (pl)
CA (1) CA3109100A1 (pl)
CL (1) CL2021000430A1 (pl)
DK (1) DK3840837T3 (pl)
EA (1) EA202190532A1 (pl)
ES (1) ES2980252T3 (pl)
FI (1) FI3840837T3 (pl)
HR (1) HRP20240694T1 (pl)
HU (1) HUE066903T2 (pl)
IL (1) IL280924B2 (pl)
LT (1) LT3840837T (pl)
MA (1) MA53427B1 (pl)
MX (1) MX2021002042A (pl)
PL (1) PL3840837T3 (pl)
PT (1) PT3840837T (pl)
RS (1) RS65608B1 (pl)
SG (1) SG11202101618PA (pl)
SI (1) SI3840837T1 (pl)
SM (1) SMT202400221T1 (pl)
WO (1) WO2020038983A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20211001A1 (es) 2018-02-27 2021-06-01 Incyte Corp Imidazopirimidinas y triazolopirimidinas como inhibidores de a2a / a2b
MA52940A (fr) 2018-05-18 2021-04-28 Incyte Corp Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
WO2020010197A1 (en) 2018-07-05 2020-01-09 Incyte Corporation Fused pyrazine derivatives as a2a / a2b inhibitors
TWI829857B (zh) 2019-01-29 2024-01-21 美商英塞特公司 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
SMT202300337T1 (it) * 2019-02-08 2023-11-13 Astrazeneca Ab Inibitori di arginasi e relativi metodi d'uso

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012027034B1 (pt) * 2010-04-22 2020-10-13 Mars, Incorporated compostos inibidores de arginase, composição farmacêutica compreendendo o referido composto, método in vitro para inibição de arginase i e ii e uso do referido composto
SG10202110144TA (en) * 2015-06-23 2021-10-28 Calithera Biosciences Inc Compositions and methods for inhibiting arginase activity
MX2019005402A (es) * 2016-11-08 2019-12-05 Calithera Biosciences Inc Terapias de combinacion del inhibidor de arginasa.
HRP20210848T1 (hr) 2016-12-22 2021-07-09 Calithera Biosciences, Inc. Sastavi i postupci za sprječavanje aktivnosti arginaze
JP7317841B2 (ja) 2018-02-17 2023-07-31 アストラゼネカ・アクチエボラーグ アルギナーゼインヒビタ及びその使用方法
EP3765006A4 (en) 2018-03-13 2022-02-23 Merck Sharp & Dohme Corp. ARGINASE INHIBITORS AND METHODS OF USE
CN111770756B (zh) 2018-04-27 2023-03-31 四川科伦博泰生物医药股份有限公司 非天然氨基酸类衍生物、包含其的药物组合物及其制备方法和用途

Also Published As

Publication number Publication date
MA53427B1 (fr) 2024-06-28
EP3840837B1 (en) 2024-03-20
RS65608B1 (sr) 2024-07-31
ES2980252T3 (es) 2024-09-30
WO2020038983A1 (en) 2020-02-27
AU2019323663A1 (en) 2021-04-08
MX2021002042A (es) 2021-04-28
HRP20240694T1 (hr) 2024-08-16
FI3840837T3 (fi) 2024-06-03
CN112584900B (zh) 2025-07-15
CA3109100A1 (en) 2020-02-27
MA53427A (fr) 2021-12-01
US20210332068A1 (en) 2021-10-28
EA202190532A1 (ru) 2021-07-08
IL280924B1 (en) 2024-06-01
SG11202101618PA (en) 2021-03-30
JP7441210B2 (ja) 2024-02-29
US11952392B2 (en) 2024-04-09
CN112584900A (zh) 2021-03-30
IL280924A (en) 2021-04-29
SMT202400221T1 (it) 2024-07-09
EP4371614A3 (en) 2025-09-24
PT3840837T (pt) 2024-06-14
EP4371614A2 (en) 2024-05-22
KR20210049120A (ko) 2021-05-04
DK3840837T3 (da) 2024-06-10
SI3840837T1 (sl) 2024-07-31
CL2021000430A1 (es) 2021-09-03
KR102668252B1 (ko) 2024-05-21
AU2019323663B2 (en) 2022-07-14
IL280924B2 (en) 2024-10-01
LT3840837T (lt) 2024-06-10
JP2021535111A (ja) 2021-12-16
EP3840837A1 (en) 2021-06-30
HUE066903T2 (hu) 2024-09-28

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